基本信息
姓名：
徐惠绵导师类别：
博导
性别：
男出生年月：
195209
学术职称：
教授业务职称：
主任医师
最后学位：
医学博士学位

院系：
第一临床学院
科室：
肿瘤外科
办公电话：
**
电子邮箱：
xuhuimian@126.com

研究方向

博士研究方向为：胃癌亚临床转移早诊与阻断治疗研究
硕士研究方向为：胃癌亚临床转移早诊与阻断治疗研究/专业学位
硕士研究方向为：胃癌亚临床转移早诊与阻断治疗研究/学术学位



教育经历

时间就读院校所获学位专业名称


工作经历

时间工作单位承担职务从事工作


社会任职

中华医学会肿瘤学分会候任主任委员兼胃肠肿瘤学组组长 中国抗癌协会胃癌专业委员会候任主任委员 辽宁省肿瘤学会主任委员 辽宁抗癌协会副理事长兼秘书长
荣誉称号

辽宁名医辽宁攀登学者辽宁省首届“十大健康卫士”


承担课题

时间课题名称下达部门课题经费
201101-201312TGF-β诱导间皮细胞成纤维转化与胃癌细胞粘附侵袭关系的研究国家自然科学基金委33万元
201301-201612M2型肿瘤相关巨噬细胞诱导腹膜微环境改变促进胃癌腹膜转移机制研究国家自然基金委员会80万元


学术论文

文章题目杂志名称发表年卷期页
Clinical analysis of superficial spreading early gastric cancer:a report of 62 casesZhonghua Wei Chang Wai Ke Za Zhi200912(2):113-6
The progress in early diagnosis and treatment of gastric cancerZhonghua Wai Ke Za Zhi200947(17):1294-7
Prognostic significance of microscopic positive margins for gastric cancer patients with potentially curative resectionAnn Surg Oncol200916(11):3028-37
A novel subclassification of pT2 gastric cancers according to the depth of muscularis propria invasion: superficial muscularis propria versus deep muscularis propria/subserosaAnn Surg**(5):768-75
Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by anti-apoptosisWorld J Gastroenterol200915(5):570-7
Improved quality of life in patients with gastric cancer after esophagogastrostomy reconstructionWorld J Gastroenterol200915(25):3183-90
Identifying the minimum number of lymph nodes required to ensure adequate pN staging: Kaplan-Meier survival analysis versus Cox regression modelAnn Surg**(2):410-1
Induction of gastric cancer cell adhesion through transforming growth factor-beta1-mediated peritoneal fibrosisJ Exp Clin Cancer Res201029(29):139
Clinicopathologic characteristics and prognosis of gastric cancer invading the subserosaJ Surg Oncol**(7):737-41
Cimetidine induces apoptosis in gastric cancer cells in vitro and inhibits tumor growth in vivoOncol Rep201023(3):693-700
Advanced gastric cancer with early cancer macroscopic appearance: is it worthy of D2 lymphadenectomy?Ann Surg Oncol201017(5):1278-90
Transforming growth factor beta1 produced in autocrine/paracrine manner affects the morphology and function of mesothelial cells and promotes peritoneal carcinomatosisInt J Mol Med201026(3):325-32
RhoC expression level is correlated with the clinicopathological characteristics of ovarian cancer and the expression levels of ROCK-I, VEGF, and MMP9Gynecol Oncol**(3):563-71
Stage and microscopic positive margins in the treatment of patients with gastric cancerAnn Surg Oncol201017(3):943-5
Early gastric cancer with signet-ring cell histologic type: risk factors of lymph node metastasis and indications of endoscopic surgerySurgery**(3):356-63
Comparison in pathological behaviours & prognosis of gastric cancers from general hospitals between China & JapanIndian J Med Res**():295-302
Log odds of positive lymph nodes: a novel prognostic indicator superior to the number-based and the ratio-based N category for gastric cancer patients with R0 resectionCancer**(11):2571-80
Human peritoneal mesothelial cell transformation into myofibroblasts in response to TGF-ß1 in vitroInt J Mol Med201127(2):187-93
Clinicopathological analysis and prognostic significance of peritoneal cytology in Chinese patients with advanced gastric cancer.ANZ J Surg201181(9):608-13
Macroscopic serosal classification predicts peritoneal recurrence for patients with gastric cancer underwent potentially curative surgeryAnn Surg Oncol201118(4):1068-80
Clinicopathologic characteristics and prognosis of signet ring cell carcinoma of the stomach: results from a Chinese mono-institutional studyJ Surg Oncol**(7):700-3
The antitumor activity of exogenous and endogenous canstatin on colorectal cancer cellsAsian Pac J Cancer Prev201112(10):2713-6
Downregulation of connective tissue growth factor inhibits the growth and invasion of gastric cancer cells and attenuates peritoneal disseminationMol Cancer201128(10):122
βig-h3 supports gastric cancer cell adhesion, migration and proliferation in peritoneal carcinomatosisMol Med Rep20126(3):558-64
Prognostic significance of tumor deposits in gastric cancer patients who underwent radical surgerySurgery**(6):871-81
Prognostic significance of lymph node station 7 for patients with gastric cancers underwent radical surgeryJ Surg Oncol**(8):805-12
Evaluation of the seventh edition of American Joint Committee on Cancer TNM staging system for gastric cancer: results from a Chinese monoinstitutional studyAnn Surg Oncol201219(6):1918-27
Gastric cancer cell supernatant causes apoptosis and fibrosis in the peritoneal tissues and results in an environment favorable to peritoneal metastases, in vitro and in vivoGastric cancer cell supernatant causes a201220(12):34
Splenic hilar lymph node metastasis independently predicts poor survival for patients with gastric cancers in the upper and/or the middle third of the stomachJ Surg Oncol**(8):786-92
Comparison different methods of intraoperative and intraperitoneal chemotherapy for patients with gastric cancer: a meta-analysisAsian Pac J Cancer Prev201213(9):4379-85
Hepatitis B virus X protein plays an important role in gastric ulcersOncol Rep201228(5):1653-8
PDCD4 functions as a suppressor for pT2a and pT2b stage gastric cancerOncol Rep201329(3):1007-12
Milky spot macrophages remodeled by gastric cancer cells promote peritoneal mesothelial cell injuryBiochem Biophys Res Commun**(3):378-83
The prognostic impact of occult lymph node metastasis in node-negative gastric cancer: a systematic review and meta-analysisAnn Surg Oncol201320(12):3927-34
Connective tissue growth factor is a positive regulator of epithelial-mesenchymal transition and promotes the adhesion with gastric cancer cells in human peritoneal mesothelial celCytokine201361(1):173-80
Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancerJ Surg Res**(2):494-502
The mannose-sensitive hemagglutination pilus strain of Pseudomonas aeruginosa shift peritoneal milky spot macrophages towards an M1 phenotype to dampen peritoneal disseminationTumour Biol201435(5):4285-93
Induction of apoptosis in human peritoneal mesothelial cells by gastric cancer cell supernatant promotes peritoneal carcinomatosisTumour Biol201435(8):8301-7
Transforming growth factor-beta1 signaling blockade attenuates gastric cancer cell-induced peritoneal mesothelial cell fibrosis and alleviates peritoneal dissemination both in vitrTumour Biol201435(4):3575-83
Tumor-associated mesothelial cells are negative prognostic factors in gastric cancer and promote peritoneal dissemination of adherent gastric cancer cells by chemotaxisTumour Biol201435(6):6105-11
Influence of different hypoxia models on metastatic potential of SGC-7901 gastric cancer cellsTumour Biol201435(7):6801-8
Peritoneal milky spots serve as a hypoxic niche and favor gastric cancer stem/progenitor cell peritoneal dissemination through hypoxia-inducible factor 1αStem Cells201432(12):3062-74
Lung cancer cells induce senescence and apoptosis of pleural mesothelial cells via transforming growth factor-beta1Tumour Biol201536(4):2657-65
TRIM24 is upregulated in human gastric cancer and promotes gastric cancer cell growth and chemoresistanceVirchows Arch**(5):525-32


著作/专利

专著名称出版社出版年承担职务
食道胃外科复杂手术-操作要领与技巧人民卫生出版社主译2011
食道胃外科常规手术-操作要领与技巧人民卫生出版社主译2011


科研奖励

奖励名称奖励级别获奖年负责人排序
胃癌转移规律及亚临床转移诊治的系列研究辽宁省科技进步一等奖20091
胃癌转移规律及亚临床转移诊治的系列研究教育部科技进步二等奖20091


研究生论文
研究生获奖
研究生就业