基本信息
姓名：
李褒曼导师类别：
硕导
性别：
女出生年月：
198012
学术职称：
副教授业务职称：
无
最后学位：
医学博士学位

院系：
代谢病分子机制与药物研究所
科室：
代谢病所
办公电话：
**-5130
电子邮箱：
baomanli1226@163.com

研究方向

硕士研究方向为：神经药理学/学术学位
硕士研究方向为：神经药理学/专业学位



教育经历

时间就读院校所获学位专业名称
199909-200407大连医科大学医学学士学位临床医学
200409-200907中国医科大学医学博士学位临床药理学


工作经历

时间工作单位承担职务从事工作
201107-至今中国医科大学副教授教师
201301-201410美国罗彻斯特大学博士后科研


承担课题

时间课题名称下达部门课题经费
201101-201312氟西汀调节星形胶质细胞Ca2+ 库作用机制的研究国家自然基金委20万元
201101-201312氟西汀调节星形胶质细胞Ca2+ 库作用机制的研究国家自然科学基金委员会20万元
201506-201806去甲肾上腺素对神经元和星形胶质细胞体积及钠钾泵活性相反作用的机制研究教育部留学回国人员科研启动基金3万元


学术论文

文章题目杂志名称发表年卷期页
Down-regulation of gene expression of the kainate receptor GluK2 (GluR6) by chronic treatment with anti-bipolar drugs in cultured astrocytes and brain.Neuropharmacology200957():375-385
Chronic treatment of astrocytes with fluoxetine enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation.Psychopharmacology**():1-12
Serotonin increases ERK(1/2) phosphorylation in astrocytes by stimulation of 5-HT(2B) and 5-HT(2C) receptors.Neurochem. Int.201057():432-439
Signaling pathways of isoproterenol-induced ERK1/2 phophorylation in primary cultures of astrocytes are concentration-dependent.J Neuochemistry**():1007-1023
Effects of chronic treatment with fluoxetine on receptor-stimulated increase of [Ca2+]i in astrocytes mimic those of acute inhibition of TRPC1 channel activity.Cell Calcium201150():42-53
Fluoxetine affects GluK2 editing, glutamate-evoked Ca(2+) influx and extracellular signal-regulated kinase phosphorylation in mouse astrocytes.J. Psychiatry Neurosci201136():322-338
Cell type-specific gene expression and editing responses to chronic fluoxetine treatment in the in vivo mouse brain and their relevance for stress-induced anhedonia.Neurochem Res201237():2480-2495
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.Neurochem Int201261():1325-1332
Cell-specific mRNA alterations in Na+, K+-ATPase α and β isoforms and FXYD in mice treated chronically with carbamazepine, an anti-bipolar drug.Neurochem Res201338():834-841
Expression of nucleoside transporter in freshly isolated neurons and astrocytes from mouse brain.Neurochem Res201338():2351-2358
Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism.Nature Communications20140():0
Cell type-specific in vivo expression of genes encoding signalling molecules in the brain in response to chronic mild stress and chronic treatment with fluoxetine.Psychopharmacology20140():0


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