基本信息
姓名：
阮强导师类别：
博导
性别：
男出生年月：
196309
学术职称：
教授业务职称：
无
最后学位：
医学硕士学位

院系：
第二临床学院
科室：
病毒研究室
办公电话：
024-96615-13421
电子邮箱：
ruanq@sj-hospital.org

研究方向

博士研究方向为：人巨细胞病毒致病机理的分子基础研究
博士研究方向为：人巨细胞病毒致病机理的分子基础研究
硕士研究方向为：人巨细胞病毒致病机理的分子基础研究/学术学位
硕士研究方向为：人巨细胞病毒致病机理的分子基础研究/学术学位



教育经历

时间就读院校所获学位专业名称
198109-198507武汉大学理学学士学位病毒学及分子生物学系
199409-199607中国医科大学医学硕士学位微生物学专业


工作经历

时间工作单位承担职务从事工作
198507-198611武汉大学团委团委副书记主持工作
198611-200110中国医科大学附属盛京医院病毒研究室助理研究员、副研究员临床检测；教学，科研
200110-今中国医科大学附属盛京医院病毒研究室教授、研究员研究生教学，科学研究


社会任职

中华医学会医学病毒学分会，第六届委员会常务委员、第七届委员会副主任委员(2010-2013)、第八届委员会副主任委员（2013-2016)； 中华医学会辽宁省分会微生物学与免疫学委员会副主任委员
承担课题

时间课题名称下达部门课题经费
201201-201412人巨细胞病毒miR-US25-2-3p对病毒复制和DNA合成影响机制研究教育部12万元
201201-201512人巨细胞病毒microRNA对宿主细胞mRNA转录后调控的生物学功能研究国家自然科学基金委员会58万元
201401-201712人巨细胞病毒潜伏感染相关基因UL138 及LUNA 转录调控机制研究国家自然科学基金委员会70万元


学术论文

文章题目杂志名称发表年卷期页
Diagnostic value of HCMV pp65 antigen detecting by FCA for symptomatic and asymptomatic infection: compared to quantification of HCMV DNA and detection of IgM antibody in infants.Med. Microbiol. Immunol.**():107
Structure characterization of human cytomegalovirus UL131A, UL130 and UL128 genes in clinical strains in China.Gen. Mol. Res.20098(3):1191
Characteristics of HPV prevalence among women in Liaoning province, China.Int. J. Gynecol. Obst.**():105
Transcription pattern of UL131A-128 mRNA in clinical strains of human cytomegalovirus.J. Biosci.201033(3):365
A rapid method to screen putative mRNA targets of any known microRNAVirol. J.20118():8
Characterization of 3’ termini of human cytomegalovirus UL138Microbiol Immunol.201155():95
Sequence analysis of human cytomegalovirus US28 gene in lowpassage clinical isolates from children and AIDS patientsActa Biochimica Polonica201158(2):231
Characterization of the Transcripts of Human Cytomegalovirus UL144Virol. J.20118():299
Novel transcripts of human cytomegalovirus clinical strain found by cDNA library screening.Gen. Mol. Res.201110(2):566
Genetic Diversity of HPV-16 E6, E7, and L1 Genes in Women With Cervical Lesions in Liaoning Province, ChinaInt J Gynecol Cancer201121():551
Interaction between human cytomegalovirus UL136 protein and ATP1B1 protein.Brazilian J. Med. Biol.Res.201144(12):1251
Transcriptional Features and Transcript Structure of UL145 in Different Strains of Human Cytomegalovirus.J. Med. Virol.201183(12):2151
Human cytomegalovirus RL13 gene transcripts in a clinical strain.Virus Genes201143(3):327
Human CMV: an overview.Future Microbiol.20127(5):577
Variant Lineages of Human Papillomavirus Type 18 in Northeast China Populations Characterized by Sequence Analysis of E6, E7, and L1 Regions.Int J Gynecol Cancer201222(6):930
Variations of human papillomavirus type 58 E6, E7, L1 genes and long control region in strains from women with cervical lesions in Liaoning province, China.Infection, Genetics and Evolution201212():1466
An antisense transcript in the human cytomegalovirus UL87 gene region.Virol. J.20128():515
Characterization of human cytomegalovirus UL146 transcriptsVirus Research**():223
Genomic Polymorphism of Human Papillomavirus Type 52 in Women from Northeast China.Int. J. Mol. Sci.201213():14962
Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, ChinaBMC Cancer201313():459
Identification of immediate early gene X-1 as a cellular target gene of hcmv-mir-UL148D.Int J Mol Med.201331():959
Transcription characteristics of the human cytomegalovirus UL13 gene.Arch Virol.**(2):473
The expression of interleukin-32 is activated by human cytomegalovirus infection and down regulated by hcmv-miR-UL112-1.Virol. J.201310(1):51
Overlapping transcription structure of human cytomegalovirus UL140 and UL141 genes.J Biosci.201338(1):35
Down-regulation of human cytomegalovirus UL138, a novel latency-associated determinant, by hcmv-miR-UL36.J. Biosci.201338(3):479
Over-expression of human cytomegalovirus miR-US25-2-3p downregulates eIF4A1 and inhibits HCMV replicationFEBS Letters**():2266
Analysis and mapping of a 3’ coterminal transcription unit derived from human cytomegalovirus open reading frames UL30--UL32Virol. J201310():65
Characterization of a novel group of antisense transcripts in human cytomegalovirus UL83 gene region.J Med Virol.201486(12):2033
Validation of three splice donor and three splice acceptor sites for regulating four novel low-abundance spliced transcripts of human cytomegalovirusUL21.5 gene locusInt J Mol Med201535(1):253
Interaction between the human cytomegalovirusencoded UL142 and cellular Snapin proteinsMol Med Rep201511(2):1069
Newly identified transcripts of UL4 and UL5 genes of human cytomegalovirus.Acta Biochim Pol. 201562(1):97
Human cytomegalovirus miR-US33-5p inhibits viral DNA synthesis and viral replication by down-regulating expression of the host Syntaxin3 FEBS Lett.**(4):440


研究生就业

毕业博士研究生8人，硕士4人；毕业的研究生，均在国内外的儿科学、内科学、临床检验、微生物学、遗传学等专业就职。在毕业的博士研究生中，现具有正高级技术职称1人、副高职技术职称4人；在毕业的硕士研究生中具有副高职技术职称1人，在美国就任临床医生1人。