男，1982.1月生，江苏省****, 江苏省“双创团队”领军人才，江苏省生物信息学专业委员会委员。曾在美国威斯康辛大学麦迪逊分校开展研究工作，先后任实习研究员，博士后等职。目前，主要从事生物信息学、表观遗传学及基因组学的研究工作。主在《PNAS》《Genome Biology》《Plant Cell》《Nucleic Acids Research》等期刊上，共发表SCI论文40余篇，总影响因子超过200，ESI高被引论文2篇，google scholar总引用超过1100次。
研究方向简介：
真核生物基因表达调控是顺式调控元件(cis-regulatory element)与反式作用因子(trans-acting factor) 相互作用的结果并受到表观遗传的影响。通过开展顺式调控元件的鉴定、功能分析及表观遗传学调控机制的研究，不仅可以深入理解基因表达的分子机制，而且可以确定具有重要农艺形状、抗逆特性的调控元件，为利用基因组编辑技术对现有优良品种进行改良提供理论依据。通过结合植物功能基因组、表观遗传学，运用生物大数据分析等方法可以对水稻等植物的调控元件进行高通量挖掘，并同时利用基因编辑技术及转基因技术等对调控元件进行有效验证。实验室网站：http://zhangtaolab.org.
近年发表论文：
2019
Xin HY?, Zhang T?, Wu YF, Zhang WL, Zhang PD, Xi ML*, Jiang JM. An extraordinarily stable karyotype of the woody Populus species revealed by chromosome painting. The Plant Journal DOI:10.1111/tpj.14536
Alvarez J.M, Moyano T.C, Zhang T, Gras D.E, Herrea F.J, Araus V. O’Brien J.A, Carrillo L, Medina J, Vicente-Carbajosa J, Jiang JM, Gutierrez R.A* Local changes in chromatin accessibility and transcriptional networks underlying the nitrate response in Arabidopsis roots Molecular Plant DOI:10.1016/j.molp.2019.09.002
Ren QR, Zhong ZH, Wang Y, You Q, Li Q, Yuan MZ, He Y, Qi CY, Tang X, Zheng XL, Zhang T*, Qi YP*, Zhang Y*. Bidirectional promoter based CRISPR-Cas9 systems for plant genome editing Frontiers in Plant Science DOI:10.3389/fpls.2019.01173
Liu XY?, Sun S?, Wu Y, Zhou Y, Gu SW, Yu HX, Yi CD, Gu MH, Jiang JM, Liu B, Zhang T*, Gong ZY*. Dual‐color oligo‐FISH can reveal chromosomal variations and evolution in Oryza species The Plant Journal DOI:10.1111/tpj.14522
Zhong ZH?, Sretenovic S?, Ren QR?, Yang LJ, Bao Y, Qi CY, Yuan MZ, He Y, Liu SS, Wang JH, Huang L, Wang Y, Baby DB, Wang D, Zhang T, Qi YP*, Zhang Y*. Improving plant genome editing with high-fidelity xCas9 and non-canonical PAM-targeting Cas9-NG Molecular Plant 2019, 12(7):1027-1036
Albert P.S?, Zhang T?, Semrau K, Rouillard JM, Kao YH, Wang CJ, Danilova T.V, Jiang JM, and Birchler J*. Whole-chromosome paints in maize reveal rearrangements, nuclear domains, and chromosomal relationships Proceedings of the National Academy of Sciences of the United States of America 2019, 16(5):1679-1685
Malzahn AA?, Tang X?, Lee K, Ren QR, Sretenovic S, Zhang YX, Chen HQ, Kang MJ, Bao Y, Zheng XL, Deng KJ, Zhang T, Salcedo V, Wang K, Zhang Y*, Qi YP*. Application of CRISPR-Cas12a temperature sensitivity for improved genome editing in rice, maize, and Arabidopsis. BMC Biology 2019, 17(1):9
Tang X?, Ren QR?, Yang LJ, Bao Y, Zhong ZH, He Y, Liu SS, Qi CY, Liu BL, Wang Y, Sretenovic S, Zhang YX, Zheng XL, Zhang T*, Qi YP*, Zhang Y*. Single transcript unit CRISPR 2.0 systems for robust Cas9 and Cas12a mediated plant genome editing. Plant Biotechnology Journal 2019, 17(7):1431-1445
2018
Wu ZG?, Fang DM?, Yang R?, Gao F, An XY, Zhou XX, Li YF, Yi CD, Zhang T, Liang CZ, Cui P*, Cheng ZK*, Luo Q*. De novo genome assembly of Oryza granulata reveals rapid genome expansion and adaptive evolution. Communications Biology 2018, 1: 84
Tang X?, Liu GQ?, Zhou JP?, Ren QR, You Q, Tian L, Xin XH, Zhong ZH, Liu BL, Zheng XL, Zhang DW, Malzahn A, Gong ZY, Qi YP*, Zhang, T*, and Zhang Y*. (2018). A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1(Cas12a) nucleases in rice. Genome Biology 2018, 19:84
You Q, Zhong ZH, Ren QR, Hassan F, Zhang Y*, Zhang T*. CRISPRMatch: An Automatic Calculation And Visualization Tool For High-throughput CRISPR Genome-editing Data Analysis. International Journal of Biological Sciences 2018, 14(8): 858-862.
Yang XM?, Zhao HN?, Zhang T, Zeng ZX, Zhang PD, Zhu B, Han YH, Braz GT, Casler MD, Schmutz J, and Jiang JM*. Amplification and adaptation of centromeric repeats in polyploid switchgrass species. New Phytologist 2018, 218:1645-1657
Hou LL?, Xu M?, Zhang T?, Xu ZH, Wang WY, Zhang JX, Yu MM, Ji W, Zhu CW, Gong ZY, Gu MH, Jiang JM and Yu HX*. Chromosome painting and its applications in cultivated and wild rice. BMC Plant Biology 2018, 18: 110.
Dong ZB?, Yu J?, Li H, Huang W, Xu L, Zhao Y, Zhang T, Xu W, Jiang JM, Su Z*, and Jin WW*. Transcriptional and epigenetic adaptation of maize chromosomes in Oat-Maize addition lines. Nucleic Acids Research 2018, 46(10): 5012-5028.
Zhong ZH?, Zhang YX?, You Q?, Tang X, Ren QR, Liu SS, Yang LJ, Wang Y, Liu XP, Liu BL, Zhang T, Zheng XL, Le Y, Zhang Y*, and Qi YP*. Plant genome editing using FnCpf1 and LbCpf1 nucleases at redefined and altered PAM sites. Molecular Plant 2018, 11: 999-1002.
Xin H?, Zhang T?, Han YH, Wu YF, Shi JS, Xi ML*, and Jiang JM. (2018) Chromosome painting and comparative physical mapping of the sex chromosomes in Populus tomentosa and Populus deltoides. Chromosoma 2018, 127(3): 313-321.
Braz GT?, He L?, Zhao HN?, Zhang T?, Semrau K, Rouillard JM, Torres GA, Jiang JM*. Comparative oligo-FISH mapping: an efficient and powerful methodology to reveal karyotypic and chromosomal evolution. Genetics 2018, 208(2): 513-523.
2017
Zhang R, Xue C, Liu GQ, Liu XY, Zhang ML, Wang X, Zhang T*, and Gong ZY*. Segmental Duplication of Chromosome 11 and its Implications for Cell Division and Genome-wide Expression in Rice. Scientific Reports 2017, 1(7): 2689.
Tang X?, Lowder LG?, Zhang T, Maizahn AA, Zheng XL, Voytas DF, Zhong ZH, Chen YY, Ren QR, Li Q, Kirkland ER, Zhang Y*, and Qi YP*. A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants. Nature Plants 2017, 3: 17018.
Marand AP, Zhang T, Zhu B, and Jiang JM*: Towards genome-wide prediction and characterization of enhancers in plants. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms 2017, 1860(1): 131-139.
Zhou JP?, Deng KJ?, Cheng Y, Zhong ZH, Tian L, Tang X, Tang AT, Zheng XL, Zhang T, Qi YP*, and Zhang Y*: CRISPR-Cas9 Based Genome Editing Reveals New Insights into MicroRNA Function and Regulation in Rice. Frontiers in Plant Science 2017, 8:1598.
2016
Zhang T, Marand A, Jiang JM*: PlantDHS: A Database for DNase I Hypertensive Sites in Plants. Nucleic Acids Research 2016, 44(D1): D1148-D1153.
2015
Zhang T?, Zhang WL?, and Jiang JM*: Genome-wide nucleosome occupancy and positioning and their impact on gene expression and evolution in plants. Plant Physiology 2015, 168(4): 1406-1416.
Han YH?, Zhang T?, Thammapichai P, Weng YQ, and Jiang JM*: Chromosome-specific painting in Cucumis species using bulked oligonucleotides. Genetics 2015, 200(3):771-779.
Zhu B?, Zhang WL?, Zhang T?, Liu B, Jiang JM*: Genome-wide prediction and validation of intergenic enhancers in Arabidopsis thaliana using open chromatin signature. The Plant Cell 2015, 27(9):2415-2426.
2014
Zhang T, Li GR, Yang ZJ, Nevo E: Adaptive evolution of duplicated hsp17 genes in wild barley from microclimatically divergent sites of Israel. Genetics and Molecular Research 2014, 13(1): 1220-1232.
Zhang WL, Zhang T, Wu YF, Jiang JM: Open Chromatin in Plant Genomes. Cytogenetic and Genome Research 2014(1-3), 143:18-27.
Yang LM?, Koo, DH?, Li D, Zhang T, Jiang JM, Luan FS, Renner SS, Henaff E, Sanseverino W, Garcia-Mas J, Casacuberta J, Senalik DA, Simon PW, Chen JF, and Weng YQ: Next-generation sequencing, FISH mapping and synteny-based modeling reveal mechanisms of decreasing dysploidy in Cucumis. The Plant Journal 2014, 77(1): 16-30.
2013
Zhang T?, Talbert PB?, Zhang WL?, Wu YF, Yang ZJ, Henikoff JG, Henikoff S, Jiang JM: The CentO satellite confers translational and rotational phasing on cenH3 nucleosomes in rice centromeres. Proceedings of the National Academy of Sciences of the United States of America 2013, 110(50): E4875–E4883.
Commentary: Heslop-Harrison, J.S. and Schwarzacher, T. Nucleosomes and centromeric DNA packaging. Proceedings of the National Academy of Sciences of the United States of America 2013, 110(50): 19974-19975.
Iovene M, Zhang T, Lou Q, Buell CR, Jiang JM: Copy number variation in potato - an asexually propagated autotetraploid species. The Plant Journal 2013, 75(1):80-89.
Wei W, Zhang T, Lin D, Yang ZJ, Guo FB: Transcriptional abundance is not the single force driving the evolution of bacterial proteins. BMC Evolutionary Biology 2013, 13(1):162.
Yang ZJ, Zhang T, Lang T, Li G, Chen G, Nevo E: Transcriptome Comparative Profiling of Barley eibi1 Mutant Reveals Pleiotropic Effects of HvABCG31 Gene on Cuticle Biogenesis and Stress Responsive Pathways. International Journal of Molecular Sciences 2013, 14(10):20478-20491.
Dong ZB, Jiang C, Chen X, Zhang T, Ding L, Song W, Luo H, Lai J, Chen H, Liu R, Jin WW: Maize LAZY1 Mediates Shoot Gravitropism and Inflorescence Development through Regulating Auxin Transport, Auxin Signaling, and Light Response. Plant Physiology 2013, 163(3):1306-1322.
2012
Zhang WL?, Zhang T?, Wu YF?, Jiang JM: Genome-Wide Identification of Regulatory DNA Elements and Protein-Binding Footprints Using Signatures of Open Chromatin in Arabidopsis. The Plant Cell 2012, 24(7):2719-2731.
招生专业：作物遗传育种、植物生物技术、生物信息学
研究方向：表观遗传学、基因组学、生物信息学
实验室网站：http://zhangtaolab.org