姓名：刘缠民 学位：博士学位
职称：教授、硕士生导师 Email：lcm9090@jsnu.edu.cn

【教育背景】
学士学位：陕西师范大学，生物教育专业硕士学位：陕西师范大学，动物学专业 博士学位：中国矿业大学，化学工艺专业

【工作经历】
2000 年至今：在江苏师范大学工作

【研究方向】
1.天然产物药物开发及药理学研究
2.环境污染物防治及毒理学研究

【工作业绩】
讲授《动物学》、《动物学实验》、《动物生物学》、《动物生物学实验》、《制药工艺学》、
《制药工艺学实验》、《制药工程学》、《化工原理》、《野外实习》等课程。参与主持了国家自然科学基金等项目 8 项。发表学术论文 60 多篇，SCI 文章近 30 篇。主要成果发表在 Journal
of Agricultural and Food Chemistry、Food and Chemical Toxicology、 Toxicology and Applied
Pharmacology、BBA—General Subjects、Free Radical Research 等 SCI
期刊上。曾获工作先进个人、教书育人先进个人、本科毕业设计优秀指导教师、最受毕业生喜爱教师等奖励。


【承担主要科研项目】
1．A 型柿原花青素络合排铅作用及对铅诱导高血脂的肝脏脂质代谢营养干预机制：江苏省科技厅自然科学科技计划面上项目，2014.7-2017.6
2．萜类保护重金属诱导的组织损伤机理及其应用胶囊的研制：徐州市科技创新重点项目，2011.6-2012.12
3．京杭大运河苏北段污染动物分子生态监测及修复体系的构建：江苏省教育厅自然科学基础研究面上项目，2007.12-2009.12

【代表性论文】
1．Chanmin Liu*, Jieqiong Ma, Sisi Liu, Zhaojun Feng, Aimin Wang. Puerarin protects mouse liver
against nickel-induced oxidative stress and in?ammation associated with the TLR4/p38/CREB pathway.
Chemico-Biological Interactions 2016, 243: 29-34.
2．Chanmin Liu*, Jieqiong Ma, Wanru Xie, Sisi Liu, Zhaojun Feng, Guihong Zheng, Aimin Wang.
Quercetin protects mouse liver against nickel-induced DNA methylation and inflammation
associated with the Nrf2/HO-1 and p38/STAT1/NF-κ B pathway. Food and Chemical Toxicology. 2015,82:
19–26.
3．Chanmin Liu*， Jieqiong Ma, Sisi Liu, Guigong Zheng, Zhaojun Feng, Jianmei Sun. Proanthocyanidins
improves lead-induced cognitive impairments by blocking endoplasmic reticulum stress and
nuclear factor-jB-mediated inflammatory pathways in rats. Food and Chemical Toxicology, 2014, 72:
295–302.
4．Chanmin Liu*, Guihong Zheng, Qinglei Ming, Chao Cheng, Jianmei Sun. Sesamin protects mouse liver
against nickel-induced oxidative DNA damage and apoptosis by the PI3K-Akt pathway. Journal of
Agricultural and Food Chemistry 2013, 61(5):1146?1154..

5 ． Chanmin Liu *, Guihong Zheng, Qinglei Ming, Jianmei Sun, Chao Cheng. Protective effect of
quercetin on lead-induced oxidative stress and endoplasmic reticulum stress in rat liver via the
IRE1/JNK and PI3K/Akt pathway. Free Radical Research. 2013, 47(3): 192-201.
6、Chanmin Liu *, Guihong Zheng, Chao Cheng, Jianmei Sun. Quercetin Protects Mouse Brain against
Lead-Induced Neurotoxicity. J Agric Food Chem. 2013, 61, 7630?7635.
7 ． Chanmin Liu *, Guihong Zheng, Qinglei Ming, Jianmei Sun, Chao Cheng. Protective effect of
puerarin on lead-induced mouse cognitive impairment via altering activities of acetyl
cholinesterase, monoamine oxidase and nitric oxide synthase. Environmental Toxicology and
Pharmacology 2013, 33(4): 464-470.
8．Chanmin Liu *, Yunzhi Sun, Jianmei Sun, Jieqiong Ma, Chao Cheng. Protective role of quercetin
against lead-induced in flammatory response in rat kidney through the ROS-mediated MAPKs and NF-κ
B pathway. Biochimica et Biophysica Acta-General Subjects 2012, 1820(10): 1693-1703.
9．Chanmin Liu *, Jieqiong Ma, Yunzhi Sun. Puerarin protects rat kidney from lead-induced apoptosis
by modulating the PI3K/Akt/eNOS pathway. Toxicology and Applied Pharmacology 2012, 258(3):
330-342.
10．Chanmin Liu *, Jieqiong Ma, Yunzhi Sun. Puerarin protects the rat liver against oxidative
stress-mediated DNA damage and apoptosis induced by lead. Experimental and Toxicologic Pathology
2012, 64(6): 575-582.
11．Chanmin Liu *, Jieqiong Ma, Yunzhi Sun. Protective role of puerarin on lead-induced alterations
of the hepatic glutathione antioxidant system and hyperlipidemia in rats. Food and Chemical
Toxicology. 2011, 49(12): 3119-3127. 12．Chanmin Liu *, Jieqiong Ma, Yunzhi Sun. Chronic
administration of troxerutin protects mouse kidney against D-galactose-induced oxidative DNA
damage. Food and Chemical Toxicology 2010, 48(10): 2809-2817.
13．Chanmin Liu, Yuanlin Zheng *, Jun Lu, Zifeng Zhang, Shaohua Fan, Dongmei Wu, Jieqiong Ma.
Quercetin protects rat liver against lead-induced oxidative stress and apoptosis. Environmental
Toxicology and Pharmacology 2010, 29(2): 158–166.
14．Chanmin Liu*, Jieqiong Ma, Yunzhi Sun. Quercetin protects the rat kidney against oxidative
stress-mediated DNA damage and apoptosis induced by lead.

Environmental Toxicology and Pharmacology, 2010, 30(3): 264-271. 15．Jieqiong Ma, Chanmin Liu*,
Zhihong Qin, Jihong Jiang. Cellular and molecular mechanisms of the ganoderma applanatum extracts
induces apoptosis on SGC-7901 Gastric canaer cells. Cell Biochemistry & Function., 2011,29(2):
175-182.
16．Jieqiong Ma, Chanmin Liu *, Zhihong Qin, Jihong Jiang, Yunzhi Sun. Ganoderma applanatum
terpenes protect mouse liver against benzo(α )pyren-induced oxidative stress and inflammation.
Environmental Toxicology and Pharmacology. 2011, 31(2): 460–468.
17 ． Guihong Zheng, Chanmin Liu *, Jianmei Sun, Zhaojun Feng, Chao Cheng. Nickel-induced oxidative
stress and apoptosis in Carassius auratus liver by JNK pathway. Aquatic Toxicology 2014, 147,105–
111.
18．Jieqiong Ma *, Jie Ding, Li Zhang, Chanmin Liu. Hepatoprotective properties of sesamin against
CCl4-induced oxidative stress-mediated apoptosis in mice via JNK pathway. Food and Chemical
Toxicology2014, 64,41–48.