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江苏师范大学生命科学学院导师教师师资介绍简介-刘曼

/2021-03-28





























姓名:刘曼
学位:博士学位 职称:校聘副教授
E-mail: liuman861214@163.com

【主要工作业绩】教学:
主要承担本科生仪器分析、生物工程设备理论课程。指导的本科生毕业论文曾获得院级优秀毕业论文。指导多名学生参加全国大学生生命科学竞赛,并取得江苏省二等奖的好成绩。
科研:
主要从事食品安全和营养方面相关研究,具体包括第一个方面:食品功能组分的分析及其功能性细胞分子机制;第二个方面:食品有效成分的分离鉴定及其防腐保鲜作用。目前主持江苏省自然科学基金(青年基金),徐州市科技
计划项目,校级博士学位教师科研支持项目,以及参与多项国家自然科学基金。在国际著名 SCI 期刊上发表论文 20 多篇,包括 Journal of Agricultural and Food
Chemistry, Food Chemistry, Food and Chemical Toxicology, Toxicological Sciences, Frontiers in
Microbiology, Journal of Chromatography
A, Journal of the Science of Food and Agriculture 等,多次参加国际会议并做大会报告和墙报展示,获得国际学术界和企业界的广泛关注。

【教育背景】
2015.1-2016.2,联合培养博士,营养和食品科学系,美国农业部人类营养研究中心,马里兰大学帕克分校,马里兰州,美国
2011.9-2016.6,博士,生物医学工程,上海交通大学,上海,中国
2009.9-2011.8,硕士,生物医学工程,上海交通大学,上海,中国
2005.9-2009.6,学士,制药工程,常州大学,常州,江苏,中国

【工作经历】
2016.8-至今,江苏师范大学生命科学学院

【研究方向】
1. 食品有效成分的分离鉴定及其防腐保鲜作用
2. 食品功能组分的分析及其功能性细胞分子机制

【承担的主要科研项目】
1. 江苏省科技厅自然科学基金青年基金,BK20181006,木犀草素激活 Nrf2/ARE 信号通路抑制赭曲霉毒素 A 肾毒性的作用及机制研究,2018/07-2021/06,19
万元,在研,主持
2. 徐州市科技局重点研发计划,保健食品肾毒性预警细胞模型的构建与评价, 2018/08-2020/07,10 万元,在研,主持
3. 北京食品营养与人类健康高精尖创新中心开放基金,20171017,基于 NFAT/IL-2 信号转导通路的米糠油三萜烯醇阿魏酸酯增强免疫力的作用及机制研究,
2017/09-2020/09,20 万元,在研,主持
4. 江苏师范大学自然科学研究项目,16XLR044,紫薯总黄酮对免疫系统的调节作用及机理,2016/12-2021/12,20 万元,在研,主持

【代表性论文】
1. Zhang M1, Liu M1, Pan SY, Pan C, Li YX, Tian J. Perillaldehyde controls postharvest black rot
caused by ceratocystis fimbriata in sweet potatoes. Frontiers in Microbiology 2018, 9, 1102.
doi.org/10.3389/fmicb.2018.01102. (IF 4.30)
2. Liu M, Yasmeen R, Fukagawa NK, Yu L, Kim YS, Wang TTY*. Dose-Dependent Responses of I3C and
DIM on T-Cell Activation in the Human T Lymphocyte Jurkat Cell Line. International Journal of
Molecular Sciences 2017 18(7): 1409; doi: 10.3390/ijms18071409. (IF 4.32)
3. Gao BY, Liu M, Huang GR, Zhang ZF, Zhao Y, Wang TTY, Zhang YQ, Liu J, Yu LL. Absorption,
distribution, metabolism and excretion of 3-MCPD 1-monopalmitate after oral administration in rats.
Journal of Agriculture and Food Chemistry 2017, 65(12): 2609-2614. ( IF 3.80)
4. Liu M1, Liu J1, Wu YZ, Gao BY, Wu PP, Shi HM, Sun XJ, Huang HQ, Wang T, Yu LL.

Preparation of five 3-MCPD fatty acid esters, and the effects of their chemical structures on acute
oral toxicity in Swiss mice, 2016. Journal of the Science of Food and Agriculture. 97(3),
841-848. (IF 2.75)
5. Liu M1, Huang GR1, Wang TT, Sun XJ, Yu LL. 3-MCPD 1-palmitate induced renal tubular cell
apoptosis in vivo by JNK/p53 pathway. 2016. Toxicological Sciences. 151, 181-192. (IF 3.854)
6. Shi HM1, Liu M1, Wang R, Gao BY, Zhang ZF, Niu YG, Yu LL. Separating four diastereomer pairs
of the dihydroflavonol glycosides from Engelhardia roxburghiana using high performance
counter-current chromatography, 2014. Journal of Chromatography A 1383, 79-87. (IF 4.169)
7. Liu M, Yang F, Shi HM, Akoh CC, Yu LL. Preparative separation of triterpene alcohol ferulates
from rice bran oil using a high performance counter-current chromatography, 2013. Food Chemistry
139, 919–924. (IF 3.391)
8. Liu M, Gao BY, Qin F, Wu PP, Shi HM, Luo W, Ma AN, Jiang YR, Xu XB, Yu LL. Acute oral toxicity
of 3-MCPD mono- and di-palmitic esters in Swiss mice and their cytotoxicity in NRK-52E rat kidney
cells, 2012. Food and Chemical Toxicology 50, 3785–3791. (IF 2.895)
9. Wang HX1, Liu M1, Weng SY, Li JJ, Xie C, He HL, Guan W, Yuan YS, Gao J. Immune mechanisms of
Concanavalin A model of autoimmune hepatitis, 2012. World Journal of Gastroenterology 18 (2):
119-125. (IF 2.369)
10. Zhang Y, Ma CH, Yu YX, Liu M, Yi CQ. Are CXCL13/CXCR5/FAK critical regulators of MSCs migration
and differentiation?, 2015. Medical Hypotheses 84 (3), 213-215. (IF 1.074)

会议论文
1. Li XZ, Liu M*, Tian J. Impact of dietary fiber from sweet potato fermented in vitro on the
diversity of gut microbiota. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 75,
2018.8.19.
2. Liu M, Huang GR, Liu J, Gao BY, Yu LL. Acute oral toxicity and nephrotoxicity mechanism(s) of
selected fatty acid esters of 3-MCPD. 249th ACS meeting, March 22-26, 2015, Denver, CO, USA, Oral.
3. Huang GR, Liu M, Shi HM, Sun XJ, Yu LL. 3-MCPD 1-monopalmitate induces apoptosis in NRK-52E
cells via activation of p53-JNK pathway. 250th ACS meeting, August 16-20, 2015, Boston, MA, USA.
Oral.
4. Liu M, Yang F, Shi HM, Akoh CC, Yu LL. High Performance Counter Current Chromatography: A
two-step preparative separation of triterpene alcohol ferulates from rice bran oil. 246th ACS
meeting, September 8-12, 2013, Indianapolis, IN, USA. Oral.
5. Liu M, Shi HM, Gao BY, Zhang XW, Yu LL. 3-MCPD 1-mono- and di-palmitate: Acute Oral Toxicity
in Swiss mice and Cytotoxicity in NRK-52E rat kidney cells. 104th AOCS Annual Meeting & Expo,
April 28-May 1, 2013, Palais des Congrès in Montréal, Québec, Canada. Poster.
6. Zhang XW, Liu M, Shi HM, Gao BY, Yu LL. 3-MCPD 1-palmitate-2-linoleate and 3-MCPD
1-linoleate-2-palmitate: Acute Oral Toxicity in Swiss mice and cytotoxicity in NRK-52E rat kidney
cells. 104th AOCS Annual Meeting & Expo, April 28-May 1, 2013, Palais des Congrès in Montréal,
Québec, Canada. Poster.
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