博士，副研究员，硕士生导师
niuxiangheng@126.com

牛湘衡，博士，副研究员，硕士生导师。2010年本科毕业于华东理工大学，随后保送硕博连读，于2015年3月获得博士学位，同年7月加入江苏大学工作。先后受到国家自然科学基金、江苏省自然科学基金等资助，主要从事新型纳米酶的开发及其环境检测和生化分析应用研究。近年来在Trends in Analytical Chemistry、Analytical Chemistry、Chemical Communications、Biosensors and Bioelectronics、Journal of Materials Chemistry B、Analytica Chimica Acta、Sensors and Actuator B: Chemical、Analyst等期刊上发表学术论文80余篇，被引1700余次，授权国家发明专利4项。科研成果先后获得吉林省科技进步二等奖等。


研究方向
新型纳米酶的开发及其在环境检测和生化分析中的应用


近期主要研究成果
[1] Xiangheng Niu, Qiurong Shi, et al. Unprecedented peroxidase-mimicking activity of single-atom nanozyme with atomically dispersed Fe–N_x moieties hosted by MOF derived porous carbon. Biosensors and Bioelectronics, 2019, 142, 111495.
[2] Xin Li, Xiangheng Niu*, et al. Emerging applications of nanozymes in environmental analysis: opportunities and trends. Trends in Analytical Chemistry, 2019, 120, 115653.
[3] Xiangheng Niu, Nan Cheng, et al. Nanozyme-based immunosensors and immunoassays: recent developments and future trends. Journal of The Electrochemical Society, 2019, in press.
[4] Hongwei Song, Xiangheng Niu*, et al. Facile colorimetric detection of alkaline phosphatase activity based on the target-induced valence state regulation of oxidase-mimicking Ce-based nanorods. Journal of Materials Chemistry B, 2019, 7, 5834-5841.
[5] Xiangheng Niu*, Yanfang He, et al. A peroxidase-mimicking nanosensor with Hg²⁺-triggered enzymatic activity of cysteine-decorated ferromagnetic particles for ultrasensitive Hg²⁺ detection in environmental and biological fluids. Sensors and Actuators B: Chemical, 2019, 281, 445-452.
[6] Xuechao Xu, Xiangheng Niu*, et al. In situ formation of fluorescent polydopamine catalyzed by peroxidase-mimicking FeCo-LDH for pyrophosphate ion and pyrophosphatase activity detection. Analytica Chimica Acta, 2019, 1053, 89-97.
[7] Xin Li, Xiangheng Niu*, et al. Highly sensitive and specific colorimetric detection of phosphate by using Zr(Ⅳ) to synergistically suppress the peroxidase-mimicking activity of hydrophilic Fe₃O₄ nanocubes. Sensors and Actuators B: Chemical, 2019, 297, 126822.
[8] Kun Ye, Xiangheng Niu*, et al. Bifunctional MIL-53(Fe) with pyrophosphate-mediated peroxidase-like activity and oxidation-stimulated fluorescence switching for alkaline phosphatase detection. Journal of Materials Chemistry B, 2019, 7, 4794-4800.
[9] Xiangheng Niu*, Kun Ye, et al. Pyrophosphate-mediated on-off-on oxidase-like activity switching of nanosized MnFe₂O₄ for alkaline phosphatase sensing. Journal of Analysis and Testing, 2019, 3, 228-237.
[10] Xiangheng Niu*, Kun Ye, et al. A review on emerging principles and strategies for colorimetric and fluorescent detection of alkaline phosphatase activity. Analytica Chimica Acta, 2019, 1086, 29-45.
[11] Wenchi Zhang, Xiangheng Niu*, et al. Pd nanoparticle-decorated graphitic C₃N₄ nanosheets with bifunctional peroxidase mimicking and on-off fluorescence enable naked-eye and fluorescent dual-readout sensing of glucose. Journal of Materials Chemistry B, 2019, 7, 233-239.
[12] Shuwen Wu, Xiangheng Niu*, et al. Colorimetric quantification and discrimination of phenolic pollutants based on peroxidase-like Fe₃O₄ nanoparticles. Sensors and Actuators B: Chemical, 2019, in press.
[13] Hongwei Song, Xiangheng Niu*, et al. Colorimetric evaluation of the hydroxyl radical scavenging ability of antioxidants using carbon-confined CoO_x as a highly active peroxidase mimic. Microchimica Acta, 2019, 186, 354.
[14] Xuechao Xu, Xiangheng Niu*, et al. Colorimetric determination of As(III) based on 3-mercaptopropionic acid assisted active site and interlayer channel dual-masking of Fe-Co-layered double hydroxides with oxidase-like activity. Microchimica Acta, 2019, in press.
[15] Hongwei Song, Xiangheng Niu*, et al. Enzyme-triggered in situ formation of Ag nanoparticles with oxidase-mimicking activity for amplified detection of alkaline phosphatase activity. Journal of Materials Chemistry B, 2019, 7, 233-239.
[16] Xuechao Xu, Xiangheng Niu*, et al. Highly sensitive colorimetric detection of arsenite based on reassembly-induced oxidase-mimicking activity inhibition of dithiothreitol-capped Pd nanozyme. Sensors and Actuators B: Chemical, 2019, 298, 126876.
[17] Linjie Wang, Xiangheng Niu*, et al. A novel alkaline phosphatase assay based on the specific chromogenic interaction between Fe³⁺ and ascorbic acid 2-phosphate. Analytical Methods, 2019, 11, 2374-2377.
[18] Linjie Wang, Xiangheng Niu*, et al. A catalytic reaction-based colorimetric assay of alkaline phosphatase activity based on oxidase-like MnO₂ microspheres. Analytical Methods, 2019, in press.
[19] Xiangheng Niu, et al. Smartphone-based sensors for on-site rapid water quality monitoring. Advanced Water Monitoring, 2019.
[20] Xiangheng Niu, et al. Nanozymes: an emerging tool to detect toxic ions. Nanozymes for Environmental Engineering, 2019.


联系方式
地址：江苏省镇江市学府路301号江苏大学化学化工学院528室
E-mail: niuxiangheng@126.com