张义全 简介


张义全,男，1985年生，副教授，硕士生导师，江苏大学优秀青年骨干教师。主要从事病原菌致病机制研究。作为负责人，承担国家自然科学基金青年科学基金和江苏省自然科学基金青年科学基金，各1项。公开发表学术论文60余篇，其中第一作者或通讯作者SCI论文30余篇，代表性杂志包括Journal of Bacteriology、Environmental Microbiology, BMC Microbiology、Future Microbiology、Frontiers in Microbiology、Frontiers in Cellular and Infection Microbiology等。参编中文专著3部，英文专著1部。

联系方式：
E-mail：zhangyiquanq@163.com

主持的科研项目：
1. 江苏省自然科学基金青年基金，BK**，CalR调控副溶血弧菌VI型分泌系统的分子机制研究，2016/07-2019/06，19万元，在研，主持；
2. 国家自然科学基金青年基金，**，副溶血弧菌ToxR对III分泌系统和耐热性直接溶血素的表达调控研究，2017/01-2019/12，18万元，在研，主持；
3. 国家自然科学基金面上项目（合作申报），**，副溶血弧菌毒力基因表达的密度感应调控机制，2017/01-2020/12，21万元，在研，共同主持；
4. 病原微生物生物安全国家重点实验室开放课题，SKLPBS1438，密度感应系统调控副溶血弧菌III型分泌系统的分子机制研究，2015/01-2016/12，20万元，已结题，主持；
5. 江苏大学科研启动基金资助项目，，H-NS调控副溶血弧菌生物膜形成的分子机制研究，2015/01-2016/12，5万元，已结题，主持。
近5年代表性论著：
1. Renfei Lu*, Hao Tang*, Yue Qiu, Wenhui Yang, Huiying Yang, Dongsheng Zhou, Xinxiang Huang, Lingfei Hu^#, Yiquan Zhang^#. Quorum sensing regulates the transcription of lateral flagellar genes in Vibrio parahaemolyticus. Future Microbiology, 2019, accepted.
2. Yiquan Zhang, Lingfei Hu, Yue Qiu, George Osei-Adjei, Hao Tang, Ying Zhang, Rui Zhang, Xiumei Sheng, Shungao Sheng, Wenhui Yang, Huiying Yang, Zhe Yin, Ruifu Yang, Xinxiang Huang, Dongsheng Zhou^#. QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulence. Environmental Microbiology, 2019, 21(3):1054-1067. (doi: 10.1111/1462-2920.14524)
3. Yiquan Zhang, Lingfei Hu, George Osei-Adjei, Ying Zhang, Wenhui Yang, Zhe Yin, Renyun Lu, Xiumei Sheng, Ruifu Yang, Xinxiang Huang^#, Dongsheng Zhou^#. Autoregulation of ToxR and its regulatory actions on major virulence gene loci in Vibrio parahaemolyticus. Frontiers in Cellular and Infection Microbiology, 2018, 8: 291. (doi: 10.3389/fcimb.2018.00291)
4. Yiquan Zhang. 2018. Genetic Regulation Analysis of Yersinia pestis. Springer book: Yersinia pestis Protocols, Chapter 22, pages 183-202.
5. He Gao*, Jialiang Xu*, Xin Lu, Jie Li, Jing Lou, Hongqun Zhao, Baowei Diao, Qiannan Shi, Yiquan Zhang^#, Biao Kan^#. Expression of hemolysin is regulated under the collective actions of HapR, Fur, and HlyU in Vibrio cholerae El Tor serogroup O1. Frontiers in Microbiology, 2018, 9: 1310. (doi: 10.3389/fmicb.2018.01310)
6. Lei Liu, Haihong Fang, Yinjuan Ding, Yaqiong Zheng, Liping Cai, Shangen Zheng^#, Yiquan Zhang^#. Transcriptional regulation between the two global regulators RovA and CRP in Yersinia pestis biovar Microtus. Current Microbiology, 2018, 8: 374. (doi: 10.3389/fcimb.2018.00347)
7. Long Chen, Yue Qiu, Hao Tang, Lingfei Hu, Wenhui Yang, Xiaojue Zhu, Xinxiang Huang, Tang Wang^#, Yiquan Zhang^#. ToxR is required for biofilm formation and motility of Vibrio parahaemolyticus. Biomedical and Environmental Sciences, 2018, 31 (11): 848-850. (doi: 10.3967/bes2018.112)
8. Renfei Lu, George Osei-Adjei, Xinxiang Huang, Yiquan Zhang^#. Role and regulation of the orphan AphA protein of quorum sensing in pathogenic Vibrios. Future Microbiology, 2018, 13: 383-391. (doi: 10.2217/fmb-2017-0165)
9. Linlin Zhang, Yiwei Weng, Yu Wu, Xueying Wang, Zhe Yin, Huiying Yang, Wenhui Yang^#, Yiquan Zhang^#. H-NS is an activator of exopolysaccharide biosynthesis genes transcription in Vibrio parahaemolyticus. Microbial Pathogenesis, 2018,116: 164-167. (doi: 10.1016/j.micpath.2018.01.025)
10. Ying Zhang, Lin Xia, Liping Lin, Hao Tang, George Osei-Adjei, Shungao Xu, Yiquan Zhang^#, Xinxiang Huang^#. Reciprocal regulation of OmpR and Hfq and their regulatory actions on the Vi polysaccharide capsular antigen in Salmonella enterica Serovar Typhi. Current Microbiology, 2018, 75 (6): 773-778. (doi: 10.1007/s00284-018-1447-7)
11. George Osei-Adjei, Xinxiang Huang, Yiquan Zhang^#. The extracellular proteases produced by Vibrio parahaemolyticus. World Journal of Microbiology & Biotechnology, 2018, 24 (5): 68. (doi: 10.1007/s11274-018-2453-4)
12. Qin Cai, Yiquan Zhang^#. Structure, function and regulation of the thermostable direct hemolysin (TDH) in pandemic Vibrio parahaemolyticus. Microbial Pathogenesis, 2018,123: 242-245. (doi: 10.1016/j.micpath.2018.07.021)
13. Yiquan Zhang, He Gao, George Osei-Adjei, Ying Zhang, Wenhui Yang, Huiying Yang, Zhe Yin, Xinxiang Huang^#, Dongsheng Zhou^#. Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus. Frontiers in Microbiology, 2017, 8. (doi: 10.3389/fmicb.2017.02005)
14. George Osei-Adjei*, He Gao*, Ying Zhang, Lingyu Zhang, Wenhui Yang, Huiying Yang, Zhe Yin, Xinxiang Huang^#, Yiquan Zhang^#, Dongsheng Zhou^#. Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus. Oncotarget, 2017, 8(39): 65809-65822. (doi: 10.18632/oncotarget.19498)
15. He Gao, Lingyu Zhang, George Osei-Adjei, Wenhui Yang, Dongsheng Zhou, Xinxiang Huang, Huiying Yang, Zhe Yin^#, Yiquan Zhang^#. Transcriptional regulation of cpsQ-mfpABC and mfpABC by CalR in Vibrio parahaemolyticus. MicrobiologyOpen, 2017, 6(4): e470. (doi: 10.1002/mbo3.470)
16. Lingyu Zhang, George Osei-Adjei, Ying Zhang, He Gao, Wenhui Yang, Dongsheng Zhou, Xinxiang Huang^#, Huiying Yang^#, Yiquan Zhang^#. CalR is required for the expression of T6SS2 and the adhesion of Vibrio parahaemolyticus to HeLa cells. Archives of Microbiology, 2017, 199(6):931-938. (doi: 10.1007/s00203-017-1361-6)
17. Yiquan Zhang, Ying Zhang, He Gao, Lingyu Zhang, Zhe Yin, Xinxiang Huang, Dongsheng Zhou, Huiying Yang, Wenhui Yang^#, Li Wang^#. Vibrio parahaemolyticus CalR down regulates the thermostable direct hemolysin (TDH) gene transcription and thereby inhibits hemolytic activity. Gene, 2017, 613: 39-44. ( doi: 10.1016/j.gene.2017.03.001)
18. Yiquan Zhang, George Osei-Adjei, Bin Ni, Haihong Fang, Lingyu Zhang, Xin Zhao, Xinxiang Huang, Huiying Yang, Wenhui Yang^#, Fengjun Sun^#. Transcription of exsD is repressed directly by H-NS in Vibrio parahaemolyticus. Microbial Pathogenesis, 2016, 97: 221-5. (doi: 10.1016/j.micpath)
19. Yiquan Zhang, Lingyu Zhang, Shuning Hou, Xinxiang Huang, Fengjun Sun, He Gao^#. The master quorum-sensing regulator OpaR is activated indirectly by H-NS in Vibrio parahaemolyticus. Current Microbiology, 2016, 73 (1): 71-6. (doi:10.1007/s00284-016-1018-8)
20. Yiquan Zhang, Fengjun Sun, Huiying Yang, Lei Liu, Bin Ni, Xinxiang Huang, Ruifu Yang, Dongsheng Zhou^#. Current Microbiology, 2015, 70 (3): 398-403. (doi: 10.1007/s00284-014-0736-z)
* 表示第一作者；# 表示通讯作者。




返回列表

---