个人信息
陈坚，博士
Email: jianchen@ujs.edu.cn

教育背景
2003.9-2007.7 浙江工业大学， 生物与环境工程学院，学士
2007.9-2010.7 南京农业大学， 生命科学学院，生物化学与分子生物学，硕士
2010.10-2014.10 意大利维罗纳大学，生物技术系，博士

工作经历
2014.11-2019.9 美国南卡罗莱纳大学，江苏省农业科学院，博士后
2020.4-现在 江苏大学，PI

以第一作者或者共同第一作者发表的文章:
1、Chen J, Clinton M, Qi G, Wang D, Liu F, and Fu ZQ. Reprogramming and remodeling: transcriptional and epigenetic regulation of salicylic acid-mediated plant defense. Journal of Experimental Botany. 2020 Feb 15 ;eraa072.(IF=5.9)
2、Chen J, Mohan R, Zhang Y, Li M, Chen H, Palmer IA, Chang M, Qi Guang, Spoel, SH, Mengiste T, Wang D, Liu F, Fu ZQ. NPR1 promotes its own and target gene expression in plant defense by recruiting CDK8. Plant Physiology. 2019 Sep;181(1):289-304. (IF=6.9) (被同刊杂志推荐：Plant Physiol. Sep 2019, 181 (1) 6-7) (中科院生物学一区)
3、Qi G, Chen J, Chang M, Chen H, Hall K, Korin J, Liu F, Wang D, Fu ZQ. Pandemonium Breaks Out: Disruption of Salicylic Acid-Mediated Defense by Plant Pathogens. Molecular Plant. 2018 Dec 3;11(12):1427-1439. (共同第一作者) (IF=10.8) (中科院生物学一区)
4、Chen J, Bellin D, Vandelle E. Measurement of Cyclic GMP During Plant Hypersensitive Disease Resistance Response. Methods Mol Biol. 2018;1743:143-151
5、Hussain J, Chen J, Locato V, Sabetta W, Behera S, Cimini S, Griggio F, Martínez-Jaime S, Graf A, Bouneb M, Pachaiappan R, Fincato P, Blanco E, Costa A, De Gara L, Bellin D, de Pinto MC, Vandelle E. Constitutive cyclic GMP accumulation in Arabidopsis thaliana compromises systemic acquired resistance induced by an avirulent pathogen by modulating local signals. Sci Rep. 2016 Nov; 4;6:36423 (共同第一作者) (IF=4.2)
6、Chen J, Vandelle E, Bellin D, Delledonne M. Detection/Function of NO during the hypersensitive response in Arabidopsis thaliana: where there’s a will there’s a way. Nitric Oxide. 2014 Dec; 43:81-88 (IF=3.5)
7、陈坚, 耿贝贝, 沈文飚, 黄丽琴 (2009) 一氧化碳在植物体内的信号转导作用。 生命的化学 29: 283-286

参与发表的文章：
1、Palmer IA, Chen H, Chen J, Chang M, Li M, Liu F, Fu ZQ. Novel Salicylic Acid Analogs Induce a Potent Defense Response in Arabidopsis. Int J Mol Sci. 2019 Jul 8;20(13).
2、Chang M, Zhao J, Chen H, Li G, Chen J, Li M, Palmer IA, Song J, Alfano JR, Liu F, Fu ZQ. PBS3 Protects EDS1 from Proteasome-Mediated Degradation in Plant Immunity. Mol Plant. 2019 Feb 11. (IF=10.8) (中科院生物学一区)
3、Li M, Chen H, Chen J, Chang M, Palmer IA, Gassmann W, Liu F, Fu ZQ. TCP Transcription Factors Interact With NPR1 and Contribute Redundantly to Systemic Acquired Resistance. Front Plant Sci. 2018 Aug 14;9:1153.
4、Chen H, Palmer IA, Chen J, Chang M, Thompson SL, Liu F, Fu ZQ. Specific and Accurate Detection of the Citrus Greening Pathogen Candidatus liberibacter spp. Using Conventional PCR on Citrus Leaf Tissue Samples. J Vis Exp. 2018 Jun 29;(136).
5、Chen H, Chen J, Li M, Chang M, Xu KM, Shang ZH, Zhao Y, Palmer I, Zhang YQ, McGrill J, Alfano JR, Nishimura MT, Liu FQ, and Fu ZQ. A Bacterial Type III Effector Targets the Master Regulator of Salicylic Acid Signaling NPR1 to Subvert Plant Immunity. Cell Host Microbe. 2017 Dec 13;22(6):777-788 (F1000Prime) (IF=17.9) (中科院生物学一区)
6、Kumar N, Astegno A, Chen J, Giorgetti A, Dominici P. Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity. Int. J. Mol. Sci. 2016, 17(5), 640
7、Chen XY, Ding X, Xu S, Wang R, Xuan W, Cao ZY, Chen J, Wu HH, Ye MB, Shen WB (2009) Endogenous hydrogen peroxide plays a positive role in the upregulation of heme oxygenase and acclimation to oxidative stress in wheat seedling leaves. J Integr Plant Biol 51: 951–960

科研项目
1、南卡罗莱纳大学博士后基金Aspire I track II B，Unravel the function of NPR1 interacting La-related proteins in plant defense response, 13010-17-44719，2017.7-2018.9，主持。
2、国家自然科学青年基金，新型植物免疫复合体PBS3-EDS1促进植物抗病性机制研究，**，2018.1-2020.12，参与
3、美国国家自然科学基金，Targeting of salicylic acid-activated NPR1 by a bacterial type III effector，**，2018.8.1-2021.7.31，49.3万美元，参与
4、美国国家自然科学基金，Salicylic acid signaling in plant pathogen interactions，13010-FC43，2015.8.1-2016.7.3，14.8万美元，参与
5、国家自然科学基金，水稻白叶枯病菌中一个新致病因子受寄主诱导及其调控致病性的机制研究，**，2016.1-2019.12，65万元，参与

研究方向：
1、水杨酸及其受体在植物免疫中的信号转导
2、丁香假单胞三型效应因子与植物免疫蛋白的互作
3、NPR1互作蛋白在植物免疫中的作用

本课题组长期招聘博士后，同时欢迎硕士生及博士生的加入







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