个人简介
姓名 张海晖
性别 男
出生日期 1975年4月
职称 教授
电话 ——
传真
Email zhanghh@ujs.edu.cn
详细介绍
【学术简介】
学习经历：
1998年毕业于吉林农业大学，获畜牧学专业学士学位； 2001年毕业于吉林农业大学，获动物营养专业硕士学位；2005年毕业于江南大学，获粮食、油脂与植物蛋白工程专业博士学位。
教学及研究经历
2005年7月于江苏大学食品与生物工程学院从事教学和科研工作，2010年江苏大学食品科学与工程博士后流动站出站。2015年美国马萨诸塞大学阿默斯特分校食品科学系访问。
学术及社会兼职：
国家自然科学基金项目网评专家，中国食品科技学会会员，江苏省生物化学学会会员， Food Chemistry，Food and Chemical Toxicology，Food & Function，Analytical Methods，《食品科学》等杂志审稿人。

【主讲课程】
硕士研究生：食品酶工程、食品毒理学
本 科 生：食品营养学、食品毒理学


【指导硕士研究方向】
1. 食品/农产品物理加工过程对营养组分的营养与安全特性研究
2. 农产品及其副产物的高附加值产品的开发与利用
3. 药食同源植物活性成分的绿色萃取新技术研究及功能评价


【研究领域】
食品营养与安全；食品化学

【主要论著】
近年发表学术论文50余篇，其中SCI收录和EI收录20篇。部分英文文章如下：
(1) Xiaoping Luo, Yuqing Duan, Wenya Yang, Haihui Zhang*, Changzheng Li, Jixian Zhang. Structural elucidation and immunostimulatory activity of polysaccharide isolated by subcritical water extraction from Cordyceps militaris. Carbohydrate Polymers. 2017, 157:794-802
(2) Haihui Zhang,Yanxiang Cheng, Yuqing Duan,Yuanqing He, Di Zhang, Protective effect of procyanidins extracted from the lotus seedpod on immune function injury induced by extremely low frequency electromagnetic field [J]. Biomedicine & Pharmacotherapy. 2016, 5:364-372.
(3) Haihui Zhang,Xiaoping Luo,Jiajia Ke, Y. Duan,Yuanqing He, Di Zhang,Procyanidins, from Castanea mollissima Bl. shell, induces autophagy following apoptosis associated with PI3K/AKT/mTOR inhibition in HepG2 cells[J]. Biomedicine & Pharmacotherapy. 2016, 81:15-24.
(4) Haihui Zhang,Yuanyuan Dai,Yanxiang Cheng, Yuqing Duan,Yuanqing He, Di Zhang, Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with Ca2+ signaling and double messenger system in mice hippocampus: reversal by procyanidin- s extracted from the lotus seedpod. Bioelectromagnetics[J]. 2016,29 :234-238.
(5) Yuqing Duan, Hui Xu, Haihui Zhang*,Xiaoping Luo,Guibo Sun,Xiaobo Sun. Procyanidins from Nelumbo nucifera Gaertn. seedpod induce autophagy mediated by reactive oxygen species generation in human hepatoma G2 cells. Biomedicine & Pharmacotherapy, 2016, 79 :135-152
(6) Xiaoping Luo, Yuqing Duan, Haihui Zhang*,Chemoprotective action of lotus seedpod procyanidins on oxidative stress in mice induced by extremely low-frequency electromagnetic field exposure. Biomedicine & Pharmacotherapy, 2016: 82:640-648
(7) Xiaoping Luo, Changzheng Li, Yuqing Duan, Haihui Zhang*, Di zhang, Can Zhang, Guibo Sun, Xiaobo Sun. Molecularly imprinted polymer prepared by Pickering emulsion polymerization for removal of acephate residues from contaminated waters. Journal of Applied Polymer Science, 2016, 133(15) :43126-43131
(8) Chunchun Yin, Yuqing Duan, Haihui Zhang*,Neuroprotective effects of lotus seedpod procyanidins on extremely low frequency electromagnetic field-induced neurotoxicity in primary cultured hippocampal neurons[J]. Biomedicine & Pharmacotherapy. 2016, 82:628-639.
(9) Yuqing Duan, Zhigao Wang, Haihui Zhang*, Yuanqing He, Rong Fan, Yan xiang Cheng, Guibo Sun, Xiaobo Sun. Extremely low frequency electromagnetic field causes cognitive impairmentoned associated with alteration of MAPKs pathway activeetion and decreased CREB phosphorylation in the hippocampus: reversal by procyanidins extracted from the lotus seedpod. Food & Function. 2014, 32: 1-9
(10) Yuqing Duan, Zhigao Wang, Haihui Zhang*,Yuanqing He, Rong Fan, Yan xiang Cheng, Guibo Sun, Xiaobo Sun. The preventive effect of lotus seedpod procyanidins on cognitive impairment and oxidative damage induced by extremely low frequency electromagnetic field exposure. Food & Function, 2013, 4 (8): 1252-1262
(11) Yuqing Duan, Jiajia Ke, Haihui Zhang*, Yuanqing He, Guibo Sun, Xiaobo Sun. Autophagic cell death of human hepatoma G2 cells mediated by procyanidins from Castanea mollissima Bl. Shell-induced reactive oxygen species generation. Chemico-Biological Interactions. 2014. 224: 13-23
(12) Yuqing Duan, Xiaoping Luo, Yu Qin, Haihui Zhang*, Guibo Sun, Xiaobo Sun, Yongsheng Yan. Determination of Epigallocatechin-3-gallate Using A Highefficiency Electrochemical Sensor Based on Molecularly Imprinted Poly (o-phenylenedia mine) Film. Journal of Applied Polymer Science. 2013, 129(5): 2882-2890
(13) H. Zhang, J.Ke, T. Shao, J.Li, Y. Duan, He, C. Zhang, G. Chen, G. Sun, X. Sun. Cytotoxic effects of chestnut shell extract on human Hepatoma G2 cells. Food and Chemical Toxicology, 2014, 66: 166-176
(14) Haihui Zhang, Yu Qin, Yuqing Duan, Feifei Xu, Can Zhang, Yongsheng Yan, Haile Ma,Yanhong Wang. Molecularly imprinted membrane possessing selectivity and adsorption behavior to targeted (-)-epigallocatechin-3-gallate (EGCG) molecule. Asian Journal of Chemistry, 2013, 25(7): 3711- 3718
(15) Haihui Zhang, Feifei Xu, Yuqing Duan, Can Zhang, Yongsheng Yan, Gui bo Sun, Xiaobo Sun. Selective adsorption and pre-concentration of morin by moleculearly imprinted polymers with chitosan beads as functional matrix. Advanced Materials Research, 2013: 756-759
(16) Yuqing Duan, Xiaoping Luo, Haihui Zhang*,Guibo Sun, Xiaobo Sun, Haile Ma. Computational approach to design electrochemical sensor and determination of acephate in aqueous solution based on molecularly imprinted poly (o-phenylenediamine)film. Analytical Methods. 2013, 5: 6449-6456
(17) Yuqing Duan, Haihui Zhang*, Feifei Xu, Bijun Xie*, Xianwen Yang, Yong Wang, Yongsheng Yan. Inhibition effect of procyanidins from lotus seedpod on mouse B16 melanoma in vivo and in vitro. Food Chemistry, 2010, 122: 84-91
(18) Yuqing Duan, Haihui Zhang*, Bijun Xie*, Yongshen Yan, Jinfeng Li, Feifei Xu, Yu Qin. Whole body gamma irradiation of albino mice: radioprotective activity of procyanidins from Nelumbo nucifera Gaertn. Seedpod. Food and Chemical Toxicology, 2010, 48: 3374-3384
(19) Yuqing Duan, Yu Qin, Feifei Xu, Haihui Zhang*, Yongsheng Yan, Can Zhang, Haile Ma. Optimization of the process parameters of synthesis of oligomeric procyanid- ins imprinted polymer. Scientific Research and Essays, 2010, 5: 2953-2964
(20) Haihui Zhang, Yuqing Duan, Bijun Xie. Proceedings of the 15th Tri-university International Joint Seminar and Symposium. 2008, 113-115

【科研项目】
主持和主要负责人在研课题
1. 国家自然科学基金，原花青素对氧化应激损伤的营养干预作用及分子机制
2. 国家公益行业专项子项，中药安全性体外神经毒性早期评价方法研究
3. 江苏省重点研发计划，莲固体废弃物综合利用关键技术研究及其产品开发
4. 扬州市科技计划项目，荷叶资源化综合利用关键技术研究及产品开发
5. 企业委托项目：双孢菇菇柄资源化利用与产品开发
结题项目：
1. 国家自然科学基金，表面分子印迹聚合物对原花青素的分离/富集行为及机理研究
2. 国家自然科学基金，板栗壳原花青素诱导肿瘤细胞自噬性死亡及其机制研究
3. 国家科技重大专项子课题，重大新药创制-早期成药性评价关键技术
4. 国家博士后基金，基于分子印迹技术分离/富集EGCG及其性能研究
5. 江苏大学高级人才基金，米糠多糖的高效制备及其生物活性研究
6. 企业委托，水果发酵产物提升面包风味的研究

【科研成果及奖励】
1. 2014年获中国轻工业联合会科技进步奖二等奖（2014年，4/5）
2. 江苏省科技厅、科技进步三等奖（2008年，4/5）；
3. 镇江市科技局、科技进步三等奖（2008年，4/5）。

【所获专利】
申请发明专利23项，授权10项
1. 一种亚临界水提取米糠多糖的方法. 授权号ZL9.1
2. 一种莲固体废弃物中多酚类物质的亚临界水萃取剂和萃取方法. 授权号ZL 26.2
3. 一种亚临界水同步萃取多糖和蛋白质的方法. 授权号ZL1.5
4. 一种膳食纤维的亚临界水萃取及其制备方法.授权号ZL8.1
5. 一种快速检测EGCG的电化学传感器的热聚合制备方法. 授权号ZL3.3
6. 一种快速检测EGCG的电化学传感器的电聚合制备方法.授权号ZL5. 2
7. 萝卜缨美容面膜粉及其制作方法.授权号ZL3.1
8. 一种萝卜缨系列配菜及其制作方法. 授权号ZL6.2
9. 一种萝卜缨营养咀嚼片及制备方法.授权号ZL 8.9
10. 一种原花青素泡腾片及其制作方法.ZL

【在读硕、博士人数】
在读硕士研究生5名，协助指导博士2名


【已毕业硕、博士人数】
已毕业硕士研究生6名


【已毕业本科生人数】
指导已毕业本科毕业生20名


【以上资料更新日期】
2018.05.11