个人简介
何金林,1986年出生,苏州大学材料与化学化工学部副教授。2006年本科毕业于苏州大学化学工程与工艺专业,2012年在苏州大学材料与化学化工学部获得博士学位,从事生物可降解高分子纳米材料的研究工作,博士论文课题获得“江苏省2009年度普通高校研究生科研创新计划项目”资助。博士在读期间,获得2010年国际高分子化学学术讨论会(PC2010)—“优秀墙报奖”和2010年江苏省博士生学术论坛(化学与绿色化工)—“优秀论文奖”。2010年8月荣获国家留学基金委公派留学基金资助,在美国Akron大学高分子科学与工程学院美国工程院院士程正迪教授课题组学习,从事功能性软物质材料的研究。2015年7月晋升为副教授,2018年7月入选苏州大学优秀青年****。2018年被英国皇家化学会J. Mater. Chem. B期刊遴选为Emerging Investigator,2019年7月荣获苏州大学“课程思政”课堂教学竞赛三等奖,2020年10月荣获苏州大学第十九届青年教师课堂教学竞赛二等奖,2020年6月荣获苏州大学本科毕业设计(论文)优秀指导教师。现承担本科生《基础化学》、《化工基础实验》和研究生《高分子研究方法》等课程的教学工作。
何金林博士已在Macromolecules、Anal. Chem、Polym. Chem.、J. Mater. Chem. B、Soft Matter和《高分子学报》等专业学术期刊发表论文多篇,现主持国家自然科学基金面上项目1项、江苏省高等学校自然科学研究重大项目1项、以及江苏省自然科学基金面上项目1项,已顺利完成国家自然科学基金青年基金、江苏省自然科学基金青年基金、高等学校博士学科点专项科研基金等科研项目6项。受邀担任ACS Nano, Chem. Mater., Macromolecules, ACS Macro Lett., ACS Appl. Mater. Interfaces, Anal. Chem., Chem. Commun., Polym. Chem., J. Mater. Chem. B, Biomacromolecules, Mol. Pharm., ACS Biomater. Sci. Eng., ACS Appl. Bio Mater., Bioconjugate Chem., Acta Biomater., Analyst, Chinese J. Polym. Sci.,《高分子学报》, J. Nanobiotechnol., Polymer, Mater. Today Chem., RSC Adv., Colloid. Surfaces B, Appl. Surface Sci., Drug Delivery等SCI学术期刊的审稿人。现为中国化学会和中国化工学会化工新材料委员会会员,担任苏州市高企培育入库项目、核心技术产品项目等评审专家。
Dr. Jinlin He is currently an associate Professor at College of Chemistry, Chemical Engineering and Materials Science, Soochow University (Suzhou, China). He received his B.Eng. in Chemical Engineering (2006) and Ph.D. in Polymer Chemistry and Physics (2012) from Soochow University. From August 2010 to November 2011, he obtained the fellowship from China Scholarship Council (CSC) and studied as an exchange Ph.D. candidate under the supervision of Professor Stephen Z. D. Cheng in College of Polymer Science and Polymer Engineering at the University of Akron. In 2012 he joined the present college as a lecturer and was promoted to associate professor in 2015. He has been selected as the Excellent Young Scholar of Soochow University and Journal of Materials Chemistry BEmerging Investigatorin 2018.
His current research interests focus on the preparation of topological polymers and smart biomedical materials viacombination of various polymer synthesis methodologies and highly-efficient organic reactions.Dr. He has published more than 80 peer-reviewed papers with a total citation of more than 1100, and obtained several financial supports including the National Natural Science Foundation China, Natural Science Foundation of Jiangsu Province, etc. Dr. He has also frequently invited for peer-reviewing for many scientific journals including ACS Nano, Chem. Mater., Macromolecules, ACS Macro Lett., ACS Appl. Mater. Interfaces, Anal. Chem., Chem. Commun., Polym. Chem., J. Mater. Chem. B, Biomacromolecules, Mol. Pharm., ACS Biomater. Sci. Eng., ACS Appl. Bio Mater., Bioconjugate Chem., Acta Biomater., Analyst, Chinese J. Polym. Sci., J. Nanobiotechnol., Polymer, Mater. Today Chem., RSC Adv., Colloid. Surfaces B, Appl. Surface Sci., Front. Chem., Drug Delivery, etc.
指导本科生科研训练:
(1)苏州大学2020届本科优秀毕业设计(论文),刺激响应性葡聚糖-阿霉素前药的合成与表征,学生:刘鹏,指导教师:何金林。
(2)苏州大学2019年第二十届“挑战杯”大学生课外学术科技作品竞赛特等奖,肿瘤微环境响应性葡聚糖前药的构建,学生:尹树杏、刘鹏,指导教师:何金林。
(3)苏州大学2019届本科优秀毕业设计(论文),导电水凝胶的设计合成与表征,学生:饶梁,指导教师:何金林。
(4)2018年江苏省高等学校大学生创新创业训练计划项目(省级,7Y),肿瘤微环境响应性天然高分子前药载体的构建,2018.05-2020.05,学生:刘鹏、尹树杏,指导教师:何金林,已结题。
(5)2014年苏州大学大学生创新创业训练计划项目(校级,2014xj021),基于葡聚糖的生物相容及生物可降解性抗肿瘤前药的合成与表征,2014.06-2016.05,学生:邓惠元、薛妍、吴玲,指导教师:倪沛红、何金林,已结题。
(6)2013年苏州大学大学生创新创业训练计划项目(校级,2013xj023),活性阴离子聚合法制备结构规整的星形聚合物,2013.06-2015.05,学生:张琳、杨冰玉,指导教师:何金林,已结题。
已发表科研论文:
2021年
(95) Lei Xu, Hairong Wang, Hongrui Tian, Mingzu Zhang, Jinlin He*, Peihong Ni. “Facile construction of noncovalent graft copolymers with triple stimuli-responsiveness for triggered drug delivery”, Polym. Chem., 2021, doi: 10.1039/D1PY00135C.
(94) Zhongguo Liu,#Ze Yang,#Xin Chen,#Rui Tan, Gang Li, Zhanhui Gan, Yu Shao, Jinlin He, Zhengbiao Zhang, Weihua Li, Wen-Bin Zhang,Xue-Hui Dong*. “Discrete giant polymeric chains based on nanosized monomers”, JACS Au, 2021, 1, 79-86.(#Equal contribution)
2020年
(93) 王彬, 张明祖, 何金林*, 倪沛红. “活性负离子聚合制备八臂星形嵌段共聚物及其氢化反应研究”, 高分子学报, 2020,51(9), 1010-1020.
(92) 梁益玮,# 刘鹏,# 尹树杏, 刘景瑞, 张明祖, 何金林*, 倪沛红. “官能团化POSS及多臂星形聚酯的合成与表征”, 高分子学报, 2020,51(4), 366-376.(#共同第一作者)
(91) Lei Li, Hongrui Tian, Jinlin He, Mingzu Zhang, Zu-Guang Li, Peihong Ni*. Fabrication of aminated poly(glycidyl methacrylate)s-based polymers for co-delivery of anticancer drug and p53 gene. J. Mater. Chem. B, 2020, 8, 9555-9565.
(90) Lianxue Zhang, Shitong Zhang, Jiaying Xu, Youyun Li, Jinlin He, Ying Yang, Tien Huynh, Peihong Ni, Guangxin Duan, Zaixing Yang,* Ruhong Zhou*. “Low-dose X?ray-responsive diselenide nanocarriers for effective delivery of anticancer agents”, ACS Appl. Mater. Interfaces, 2020, 12, 43398-43407.
(89) Kunming Che, Mingzu Zhang, Jinlin He, Peihong Ni*. Polyphosphoester-modified cellulose nanocrystals for stabilizing pickering emulsion polymerization of styrene. Chinese J. Polym. Sci., 2020, 38, 921-931.
(88) Hongping Li, Jinlin He, Mingzu Zhang, Jian Liu, Peihong Ni*. “Glucose-sensitive polyphosphoester diblock copolymer for insulin delivery system”, ACS Biomater. Sci. Eng., 2020, 6, 1553-1564.
(87) Jiangnan Hu, Yuanzhe Liu, Mingzu Zhang*, Jinlin He, Peihong Ni. “A separator based on cross-linked nano-SiO2and cellulose acetate for lithium-ion batteries”, Electrochim. Acta, 2020, 334, 135585.
2019年
(86) Hua Chai, Wenbo Cheng, Lei Xu, Huiqiang Gui, Jinlin He*, and Peng Miao*. “Fabrication of polymeric ferrocene nanoparticles for electrochemical aptasensing of protein with target catalyzed hairpin assembly”, Anal. Chem., 2019, 91, 9940-9945.
(85) Qiangyu Qian,?Jun Xu,?Mingzu Zhang, Jinlin He*, Peihong Ni. “Versatile construction of single-tailed giant surfactants with hydrophobic poly(ε-caprolactone) tail and hydrophilic POSS head”, Polymers, 2019, 11, 311. (? Equal contribution)
(84) Ying Hao, Jinlin He, Xun Ma, Lin Feng, Mo Zhu, Yuanxin Zhai, Yang Liu, Peihong Ni, Guosheng Cheng*. “A fully degradable and photocrosslinked polysaccharide-polyphosphate hydrogel for tissue engineering”, Carbohyd. Polym., 2019, 225, 115257.
(83) Shuxiang Dong, Jinlin He, Yue Sun, Dian Li, Lei Li, Mingzu Zhang, Peihong Ni*. “Efficient Click Synthesis of Protonize & Reduction-Sensitive Amphiphilic Small Molecule Prodrug Containing Camptothecin and Gemcitabine for Drug Self-Delivery System”, Mol. Pharmaceutics, 2019, 16, 3770-3779.
(82) Rui Tan, Dongdong Zhou, Baolei Liu, Yanxiao Sun, Xinxin Liu, Zhuang Ma, Deyu Kong, Jinlin He, Zhengbiao Zhang, Xue-Hui Dong*. “Precise modulation of molecular weight distribution for structure engineering”, Chem. Sci., 2019, 10, 10698-10705.
(81)Shuxiang Dong, Yue Sun, Jie Liu, Lei Li, Jinlin He, Mingzu Zhang, Peihong Ni*. “Multifunctional polymeric prodrug with simultaneous conjugating camptothecin and doxorubicin for pH/reduction dual-responsive drug delivery”, ACS Appl. Mater. Interfaces, 2019, 11, 8740-8748.
(80)Lei Li, Yue Song, Jinlin He, Mingzu Zhang, Jian Liu, Peihong Ni*. “Zwitterionic shielded polymeric prodrug with folate-targeting and pH responsiveness for drug delivery”, J. Mater. Chem. B, 2019, 7, 786-795.
(79) Dian Li, Yue Song, Jinlin He, Mingzu Zhang, Peihong Ni*. “Polymer-doxorubicin prodrug with biocompatibility, pH response and main chain breakability prepared by catalyst-free click reaction”, ACS Biomater. Sci. Eng., 2019, 5, 2307-2315.
(78) Yue Song, Dian Li, Jinlin He, Mingzu Zhang, Peihong Ni*. “Facile preparation of pH-responsive PEGylated prodrugs for activated intracellular drug delivery”, Chinese Chem. Lett., 2019, 30, 2027-2031.
(77)Yongjuan Li, Jian Hu, Xun Liu, Yong Liu*, Shixian Lv, Juanjuan Dang, Yong Ji*, Jinlin He, Lichen Yin*. “Photodynamic therapy-triggered on-demand drug release from ROS-responsive core-cross-linked micelles toward synergistic anti-cancer treatment”, Nano Res., 2019, 12, 999-1008.
(76) Nengxin Wei, Jiangnan Hu, Mingzu Zhang*, Jinlin He, Peihong Ni. “Cross-linked porous polymer separator using vinyl-modified aluminum oxide nanoparticles as cross-linker for lithium-ion batteries”, Electrochim. Acta, 2019, 307, 495-502.
(75)Xingxing Shi, Peng Yang, Xiangfang Peng, Chuhao Huang, Qiangyu Qian, Bin Wang, Jinlin He, Xianhu Liu, Yiwen Li*, Tairong Kuang*. “Bi-phase fire-resistant polyethylenimine/graphene oxide/melanin coatings using layer by layer assembly technique: Smoke suppression and thermal stability of flexible polyurethane foams”, Polymer, 2019, 170, 65-75.
2018年
(74)Xiao-Man Wang,?Yu Shao,?Peng-Fei Jin,Wenbo Jiang,Wei Hu,Shuguang Yang,Weihua Li,* Jinlin He*, Peihong Ni, Wen-Bin Zhang*. “Influence of regio-configuration on the phase diagrams of double-chain giant surfactants”, Macromolecules, 2018, 51, 1110-1119. (? Equal contribution)
(73)Pengfei Ju,?Jian Hu,?Fei Li, Youwen Cao, Lei Li, Dongjian Shi, Ying Hao, Mingzu Zhang, Jinlin He*, Peihong Ni*. “A biodegradable polyphosphoester-functionalized poly(disulfide)s nanocarrier for reduction-triggered intracellular drug delivery”, J. Mater. Chem. B, 2018, 6, 7263-7273. (? Equal contribution) (Invited Article for 2018 Emerging Investigators Themed Issue)https://pubs.rsc.org/en/journals/articlecollectionlanding?sercode=tb&themeid=76c5076b-88fe-4a6d-a134-29e5bb6ae036
(72)Yanyan Zhou, Lei Li, Wei Chen, Dian Li, Nianchen Zhou, Jinlin He*, Peihong Ni, Zhengbiao Zhang*, Xiulin Zhu. “Twin-tailed tadpole-shaped amphiphilic copolymer of poly(ethylene glycol) and cyclic poly(?-caprolactone): Synthesis, self-assembly and biomedical application”, Polym. Chem., 2018, 9, 4343-4353.
(71) 徐俊, 钱强雨,何金林*, 张明祖, 戴礼兴, 倪沛红. “负离子聚合制备环氧化八臂星形聚异戊二烯及其表征”, 高分子学报, 2018, 3, 356-365.
(70) Xiaoming Sun,?Hongbo Zhang,?Jinlin He,?Ruoyu Cheng, Youwen Cao, Kunming Che, Liying Cheng, Lu Zhang, Guoqing Pan, Peihong Ni, Lianfu Deng, Yuguang Zhang*, Hélder A. Santos*, Wenguo Cui*. “Adjustable hardness of hydrogel for promoting vascularization and maintaining stemness of stem cells in skin flap regenerationc”, Appl. Mater. Today, 2018, 13, 54-63. (? Equal contribution)
(69) Zhe Liu, Yupeng Huang, Xiaolong Zhang, Xiaoyan Tu, Mingqi Wang, Liwei Ma, Baoyan Wang, Jinlin He, Peihong Ni, Hua Wei*. “Fabrication of cyclic brush copolymers with heterogeneous amphiphilic polymer brushes for controlled drug release”, Macromolecules, 2018, 51, 7672-7679.
(68)Luming Gu, Mingzu Zhang*, Jinlin He, Peihong Ni. “A porous cross-linked gel polymer electrolyte separator for lithium-ion batteries prepared by using zinc oxide nanoparticle as a foaming agent and filler”, Electrochim. Acta, 2018, 292, 769-778.
(67)Peng-Fei Jin,?Yu Shao,?Guang-Zhong Yin, Shuguang Yang, Jinlin He, Peihong Ni, Wen-Bin Zhang*. “Janus [3:5] polystyrene-polydimethylsiloxane star polymers with a cubic core”, Macromolecules, 2018, 51, 419-427. (? Equal contribution)
(66)Jie Liu, Jinlin He, Mingzu Zhang, Guoqiang Xu and Peihong Ni*. “A synergistic polyphosphoester-based co-delivery system of an anticancer drug doxorubicin and the tumor suppressor gene P53 for lung cancer therapy”, J. Mater. Chem. B, 2018, 6, 3262-3273.
(65) Youwen Cao, Jinlin He, Jie Liu, Mingzu Zhang and Peihong Ni*. “Folate-conjugated polyphosphoester with reversible cross-linkage and reduction sensitivity for drug delivery”, ACS Appl. Mater. Interfaces, 2018, 10, 7811-7820.
(64)Guoqing Ma, Jie Liu, Jinlin He, Mingzu Zhang, Peihong Ni*. “Dual-responsive polyphosphoester-doxorubicin prodrug containing diselenide bond: Synthesis, characterization and drug delivery”, ACS Biomater. Sci. Eng., 2018, 4, 2443-2452.
(63)Lei Li, Dian Li, Mingzu Zhang, Jinlin He, Jian Liu, Peihong Ni*. “One-pot synthesis of pH/redox responsive polymeric prodrug and fabrication of shell cross-linked prodrug micelles for antitumor drug transportation”, Bioconjugate Chem., 2018, 29, 2806-2817.
(62)Debabrata Maiti, Yu Chao, Ziliang Dong, Xuan Yi, Jinlin He, Zhuang Liu, Kai Yang*. “Development of thermosensitive protein conjugated nanogel for enhanced radio-chemotherapy of cancer”, Nanoscale, 2018, 10, 13976-13985.
(61) Xiao-Yan Tu, Chao Meng, Yun-Fei Wang, Li-Wei Ma, Bao-Yan Wang, Jin-Lin He, Pei-Hong Ni, Xiang-Ling Ji, Ming-Zhu Liu* and Hua Wei*. “Fabrication of Thermosensitive cyclic brush copolymer with enhanced therapeutic efficacy for anticancer drug delivery”, Macromol. Rapid Commun., 2018, 39, **(1-8).
2017年
(60) Xiao-Man Wang,#Yu Shao,#Jun Xu, Xin Jin, Rui-Hao Shen, Peng-Fei Jin, Dong-Wei Shen, Jing Wang, Weihua Li,Jinlin He*, Peihong Ni and Wen-Bin Zhang*. “Precision synthesis and distinct assembly of double-chain giant surfactant regio-isomers”,Macromolecules,2017,50, 3943-3953. (#Equal contribution)
(59) 晏雪生,#徐俊,#何金林*,张明祖,戴礼兴,倪沛红.“活性负离子聚合法制备POSS基七臂星形聚合物及其表征”,高分子学报,2017,3, 454-464.(#共同第一作者)
(58) Zixu Gu, Jun Cheng, Mingzu Zhang,Jinlin Heand Peihong Ni*. “Effect of sequence structure on wetting behaviors of fluorinated methacrylate polymers based on perfluorohexylethyl methacrylate and stearyl acrylate”,Chinese J. Polym. Sci.,2017, 35, 1061-1072.
(57)Xueqiong Du, Yue Sun, Mingzu Zhang,Jinlin Heand Peihong Ni*. “Polyphosphoester-camptothecin prodrug with reduction-response preparedviaMichael addition polymerizationand click reaction”,ACS Appl. Mater. Interfaces,2017,9, 13939-13949.
(56)Yue Sun, Xueqiong Du,Jinlin He, Jian Hu, Mingzu Zhang and Peihong Ni*. “Dual-responsive core-crosslinked polyphosphoester-based nanoparticles for pH/redox-triggered anticancer drug delivery”,J. Mater. Chem. B,2017, 5, 3771-3782.
(55)Zixu Gu, Jun Cheng, Mingzu Zhang,Jinlin He, and Peihong Ni*. “Effect of groups at α-position and side-chain structure of comonomers on surface free energy and surface reorganization of fluorinated methacrylate copolymer”,Polymer,2017,114, 79-87.
2016年
(54)Kan Yue,#Mingjun Huang,#Ryan Marson,#Jinlin He, Jiahao Huang, Zhe Zhou, Jing Wang, Chang Liu, Xuesheng Yan, Kan Wu, Zaihong Guo, Hao Liu, Wei Zhang, Peihong Ni, Chrys Wesdemiotis, Wen-Bin Zhang,* Sharon C. Glotzer* and Stephen Z. D. Cheng*. “Geometry Induced Sequence of Nanoscale Frank-Kasper and Quasicrystal Mesophases in Giant Surfactants”,Proc Natl Acad Sci USA,2016,113, 14195-14200. (#Equal contribution)
(53)Yu Shao, Hang Yin, Xiao-Man Wang, Shuai-Yuan Han, Xuesheng Yan, Jun Xu,Jinlin He*, Peihong Ni and Wen-Bin Zhang*. “Mixed [2:6] hetero-arm star polymers based on Janus POSS with precisely defined arm distribution”,Polym. Chem.,2016,7, 2381-2388.
(52)Jian Tian,# Jie Chen,# Cuicui Ge, Xu Liu,Jinlin He*, Peihong Ni and Yue Pan*. “Synthesis ofPEGylated ferrocene nanoconjugates asthe radiosensitizer of cancer cells”,Bioconjugate Chem., 2016, 27, 1518-1524.(#Equal contribution)
(51)Dongling Cao,Jinlin He, Jiaying Xu, Mingzu Zhang, Lin Zhao, Guangxin Duan, Youwen Cao, RuhongZhou* and Peihong Ni*. “Polymeric prodrugs conjugated with reduction-sensitive dextran-camptothecin and pH-responsive dextran-doxorubicin: An effective combinatorial drug delivery platform for cancer therapy”,Polym. Chem.,2016,7, 4198-4212.
(50)Sen Li,Jinlin He*, Mingzu Zhang, Hairong Wang and Peihong Ni*. “Multicompartment morphologies self-assembled from fluorinated ABC triblock terpolymers: Effects of flexible and rigid hydrophobic moieties”,Polym. Chem.,2016,7, 1773-1781.
(49)Zixu Gu, Mingzu Zhang,Jinlin Heand Peihong Ni*. “Surface energy and surface reorganization of perfluorohexylethyl methacrylate/n-alkyl(meth)acrylate copolymers”,Colloids Surf. A: Physicochem. Eng. Asp.,2016,502, 159-167.
(48)Jian Hu,Mingzu Zhang,Jinlin HeandPeihong Ni*. “Injectable hydrogels by inclusion complexation between three-armed star copolymer (mPEG-acetal-PCL-acetal-)3and α-cyclodextrin for pH-triggered drug delivery”,RSC Adv.,2016,6, 40858-40868.
2015年
(47)Qingqing Zhang,Jinlin He*, Mingzu Zhang and Peihong Ni*. “Polyphosphoester-conjugated camptothecin prodrug with disulfide linkage forpotent reduction-triggered drug delivery”,J. Mater. Chem. B,2015,3, 4922-4932.
(46)Fei Li,Jinlin He*, Mingzu Zhang, Peihong Ni*. “A pH-sensitive and biodegradable supramolecular hydrogel constructedfrom PEGylated polyphosphoester-doxorubicin prodrug anda-cyclodextrin”,Polym. Chem.,2015,6, 5009-5014.
(45)Jian Hu,Jinlin He*, Mingzu Zhang, Peihong Ni*. “Precise modular synthesis and structure-property study of acid-cleavable star-block copolymers for pH-triggered drug delivery”.Polym. Chem.,2015,6, 1553-1566.
(44)Fei Li,Jinlin He, Mingzu Zhang, Kam Chiu Tam, Peihong Ni*. “Injectable supramolecular hydrogels fabricated from PEGylated doxorubicin prodrug anda-cyclodextrin for pH-triggered drug delivery”,RSC Adv.,2015,5, 54658-54666.
(43)Hairong Wang,Jinlin He, Dongling Cao, Mingzu Zhang, Fei Li, Kam Chiu Tam and Peihong Ni*. “Synthesis of an acid-labile polymeric prodrug DOX-acetal-PEG-acetal-DOX with high drug loading content for pH-triggered intracellulardrug release”,Polym. Chem.,2015,6,4809-4818.
(42)Hairong Wang,Jinlin He, Mingzu Zhang, Kam Chiu Tam*, Peihong Ni*. “A new pathway towards polymer modified cellulose nanocrystalsviaa “grafting onto” process for drug delivery”, Polym. Chem.,2015,6, 4206-4209.
(41)Jian Hu,Jinlin He, Dongling Cao, Mingzu Zhang, Peihong Ni*. “Core cross-linked polyphosphoester micelles with folate-targeted and acid-cleavable features for pH-triggered drug delivery”,Polym. Chem.,2015,6, 3205-3216. (Front Cover)
(40)Jian Hu,Jinlin He, Mingzu Zhang, Peihong Ni*. “Folate-conjugated biodegradable core cross-linked polyphosphoester micelles for targetedand pH-triggered drug delivery”,J. Controlled Release, 2015,213, e86-e87.
(39)Dazhao Wu,Jinlin He, Mingzu Zhang*, Peihong Ni, Xiaofei Li, Jiankang Hu. “Fabrication of a novel sandwich-like composite separator with enhanced physical and electrochemical performances for lithium-ion battery”,J. Power Sources,2015,290, 53-60.
(38)Xiaofei Li,Jinlin He, Dazhao Wu, Mingzu Zhang*, Juwen Meng, Peihong Ni. “Development of plasma-treated polypropylene nonwoven-based composites for high-performance lithium-ion battery separators”,Electrochim. Acta,2015,167, 396-403.
(37)Xingqiang Huang,Jinlin He, Ying Hao, Min Ye, Qi Zhang, Peihong Ni, Jian Liu*. “Synthesis of PEGylated brush-type copolymers for a plurality of plug-and-play functions”,RSC Adv.,2015,5, 50019-50023.
(36)Kai Ren, Mingzu Zhang,Jinlin He, Yixian Wu, Peihong Ni*. “Preparation of polymeric prodrug paclitaxel-poly(lactic acid)-b-polyisobutylene and its application in coatings of drug eluting stent”, ACS Appl. Mater. Interfaces,2015,7, 11263-11271.
2014年
(35)Yang Zhang,Jinlin He*,Dongling Cao, Mingzu Zhang, Peihong Ni*. “Galactosylatedreduction and pH dual-responsive triblockterpolymer Gal-PEEP-a-PCL-ss-PDMAEMA: a multifunctionalcarrier for targeted and simultaneous delivery of doxorubicin and DNA”.Polym. Chem.,2014,5, 5124-5138.
(34)Jiao Bian, YingHao,Jinlin He*, WenlingZhang, Mingzu Zhang, Peihong Ni*. “Synthesis and characterization ofabiodegradable ABC triblock terpolymerasco-delivery carrier of doxorubicin and DNA”.J. Polym. Sci., Part A: Polym. Chem.,2014,52, 3005-3016.
(33)Ying Hao,Jinlin He, Sen Li, Jian Liu,Mingzu Zhang, Peihong Ni*, “Synthesisof acid-cleavable and fluorescent amphiphilic block copolymer as a combineddelivery vector of DNA and doxorubicin”,J. Mater. Chem. B,2014,2, 4237-4249.
(32)Yunfeng Tao,Jinlin He,Mingzu Zhang, Ying Hao, Jian Liu, Peihong Ni*. “Galactosylated biodegradable poly(ε-caprolactone-co-phosphoester) randomcopolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin”,Polym. Chem.,2014,5,3443-3452.
(31)肖燕,何金林,陶云锋,张明祖,胡健,倪沛红*. “基于功能化聚磷酸酯嵌段共聚物的微凝胶和水凝胶的制备与表征”,高分子学报,2014,1, 122-130.
(30)XiaofeiLi, Mingzu Zhang*,Jinlin He,Dazhao Wu, Juwen Meng, Peihong Ni. “Effects offluorinated SiO2nanoparticles on thethermal and electrochemical properties of PP nonwoven/PVdF-HFP compositeseparator for Li-ion batteries”,J.Membr. Sci.,2014,455, 368-374.
(29)李森, 张明祖,何金林,倪沛红*. “含氟聚甲基丙烯酸酯/聚异丁烯嵌段共聚物的成膜性质研究”,高分子学报,2014,12, 1648-1658.
(28)郝莹,张洋,何金林,尚修娟,张明祖,倪沛红*. “半乳糖胺修饰阳离子型刷形嵌段共聚物的合成与表征”,化学学报,2014,72,569-576.
2013年
(27)胡健,#何金林,#张明祖,倪沛红*. “点击化学在拓扑结构聚合物合成中的应用”,高分子学报, 2013,3, 300-319. (#共同第一作者)
(26)YingHao,Jinlin He, Mingzu Zhang,Yunfeng Tao, Jian Liu, Peihong Ni*. “Synthesis andcharacterization of novel brush copolymers with biodegradable polyphosphoesterside chains for gene delivery”.J.Polym. Sci., Part A: Polym. Chem.,2013,51, 2150-2160.(Highlighted by MaterialsViews)http://www.materialsviews.com/spotlight-on-polymer-chemistry-volume-51-issue-10/.http://www.materialsviews.com/brush-copolymers-for-gene-delivery/
(25)Hairong Wang,JinlinHe, Mingzu Zhang, Yunfeng Tao, Fei Li, Kam Chiu Tam, Peihong Ni*. “Biocompatibleand acid-cleavable poly(ε-caprolactone)-acetal-poly(ethyleneglycol)-acetal- poly(ε-caprolactone)triblock copolymers: synthesis, characterization and pH-triggered doxorubicindelivery”,J.Mater. Chem. B,2013,1, 6596-6607.(Inside Front Cover)
(24)Hairong Wang, Jinlin He, Mingzu Zhang, Peihong Ni*, “Amphiphilic poly(ε-caprolactone)-acetal- poly(ethylene glycol)-acetal-poly(ε-caprolactone) triblock copolymers: Synthesis, characterization and pH-sensitive drug delivery”, J. Controlled Release, 2013, 172, e60-e61.
(23)KanYue,Jinlin He, Chang Liu,Mingjun Huang, Xue-Hui Dong, Kai Guo, Peihong Ni, Chrys Wesdemiotis,Roderic P. Quirk,*Stephen Z. D. Cheng,* Wen-Bin Zhang*. “Anionicsynthesis of a “Clickable” middle-chain azide-functionalized polystyrene andits application in shape amphiphiles”. ChineseJ. Polym. Sci.,2013,31(1), 71-82. (Invitedarticle)
(22)Guoyi Zhang, Mingzu Zhang,JinlinHe, Peihong Ni*.“Synthesis and characterizationof a new multifunctional polymeric prodrug paclitaxel-polyphosphoester-folicacid for targeted drug delivery”, Polym.Chem.,2013,4, 4515-4525.
(21)JiaoBian, Mingzu Zhang,Jinlin He,Peihong Ni*. “Preparation andself-assembly of double hydrophilic poly(ethylethylene phosphate)-block-poly[2-(succinyloxy)ethylmethacrylate] diblock copolymers for drug delivery”.React. Funct. Polym.,2013, 73, 579-587.
(20)Huaichao Wang, Mingzu Zhang, Peihong Ni*,Jinlin He, Ying Hao, Yixian Wu.“Synthesis of pH-responsive amphiphilic diblock copolymers containingpolyisobutyleneviaoxyanion-initiated polymerization and their multiple self-assembly morphologies”.Chinese J.Polym. Sci.,2013,31(2): 218-231. (Front Cover)
(19)徐玲妍,张明祖*, 孟菊雯,何金林, 李晓菲, 倪沛红,“改性SiO2/PVdF-HFP/PP无纺布复合膜的制备及其电化学性能”,高分子材料科学与工程,2013,29(1), 175-178.
2012年
(18)Wen-Bin Zhang,#JinlinHe,#Kan Yue,#Chang Liu, Peihong Ni,Roderic P. Quirk*,Stephen Z. D.Cheng*.“Rapid and efficient anionic synthesis of well-definedeight-arm star polymers using octavinylPOSS and poly(styryl)lithium”.Macromolecules,2012,45, 8571-8579. (#Equal contribution)
(17)JinlinHe, Mingzu Zhang, Peihong Ni*.“Rapidlyin situformingpolyphosphoester-based hydrogels for injectable drug delivery carriers”.Soft Matter,2012,8, 6033-6038.
(16)Jinlin He,#Kan Yue,#YuqingLiu, Xinfei Yu,Peihong Ni,Kevin A. Cavicchi,RodericP. Quirk,Erqiang Chen*,Stephen Z. D. Cheng*, Wen-BinZhang*. “Fluorinated polyhedral oligomeric silsesquioxane-based shapeamphiphiles: Molecular design, topological variance, and facile synthesis”.Polym. Chem.,2012,3, 2112-2120.(#Equal contribution)
(15)YingHao, Mingzu Zhang,Jinlin He,Peihong Ni*. “Magnetic DNA vector constructed from PDMAEMA polycation andPEGylated brush-type polyanion with cross-linkable shell”.Langmuir, 2012,28, 6448-6460.
(14)HaiyanShao, Mingzu Zhang,Jinlin He,Peihong Ni*. “Synthesis and characterization of amphiphilic poly(e-caprolactone)-b-polyphosphoester diblock copolymersbearing multifunctional pendant groups”.Polymer,2012,53, 2854-2863.
(13)孟菊雯,张明祖*,倪沛红,徐玲妍,何金林,李晓菲,“改性纳米SiO2对PVdF-HFP膜形态和性能影响的研究”, 功能材料, 2012, 21, 2577-2581.
2011年
(12)Jinlin He, Haiyan Shao, Mingzu Zhang, Peihong Ni*. “Novel pH-responsive polyphosphoester-based hydrogelswith fast gelation”.J. Controlled Release,2011,152, e232-e233.
(11)Wen-Bin Zhang,JinlinHe, Xuehui Dong, Chien-Lung Wang, Hui Li, Fuai Teng, Xiaopeng Li, ChrysWesdemiotis, Roderic P. Quirk*, Stephen Z.D. Cheng*. “Improved synthesis of fullerynes by Fisher esterification for modular and efficient construction offullerene polymers with high fullerene functionality”.Polymer,2011,52, 4221-4226.
2010年
(10)Jinlin He, Peihong Ni*,Sai Wang, Haiyan Shao, Mingzu Zhang, Xiulin Zhu*. “Synthesis and physicochemical characterization of biodegradable and pH-responsive hydrogelsbased on polyphosphoester for protein delivery”.J. Polym. Sci., Part A: Polym. Chem.,2010,48, 1919-1930.
(9)WenlingZhang,Jinlin He, Zhuang Liu,Peihong Ni*, Xiulin Zhu*. “Biocompatible and pH-responsive triblock copolymermPEG-b-PCL-b-PDMAEMA: Synthesis, self-assembly and application”.J. Polym. Sci., Part A: Polym. Chem.,2010,48, 1079-1091.
(8)MingzuZhang,Jinlin He, Jiang Mao,Cuicui Liu, Hairong Wang, Yinfeng Huang, Peihong Ni*. “Kinetics of styrene miniemulsion polymerization using poly[(stearylmethacrylate-co-(N,N-dimethylamino)ethyl methacrylate] assurfactant”.Colloids Surf. A:Physicochem. Eng. Asp.,2010, 360, 190-197.
(7)XuLiu, Peihong Ni*,Jinlin He,Mingzu Zhang. “Synthesis and micellization of pH/temperature-responsivedouble-hydrophilic diblock copolymers polyphosphoester-block- poly[2-(dimethylamino)ethyl methacrylate] prepared via ROPand ATRP”,Macromolecules,2010,43, 4771-4781.
2009年
(6)CuicuiLiu,Jinlin He, Qun Zhao,Mingzu Zhang, Peihong Ni*. “Well-defined poly[(dimethylamino)ethylmethacrylate]-b-poly(fluoroalkylmethacrylate) diblock copolymers: Effects of different fluoroalkyl groups onthe solution properties”,J. Polym. Sci.,Part A: Polym. Chem.,2009,47, 2702-2712.
(5)ZixuGu, Yuan Yuan,Jinlin He,Mingzu Zhang, Peihong Ni*. “Facile approach for DNA encapsulation in functionalpolyion complex for triggered intracellular gene delivery: Design, synthesis,and mechanism”.Langmuir,2009,25, 5199-5208.
(4)GuixiangSun, Mingzu Zhang,Jinlin He,Peihong Ni*. “Synthesis of amphiphilic cationic copolymerspoly[2-(methacryloyloxy)ethyl trimethylammonium chloride-co-stearyl methacrylate] and their self-assembly behavior in waterand water-ethanol mixtures”,J. Polym.Sci., Part A: Polym. Chem.,2009,47, 4670-4684.
2008年
(3)HuZhang, Peihong Ni*,Jinlin He,Cuicui Liu. “Novel fluoroalkyl end-capped amphiphilic diblock copolymers withpH/temperature response and self-assembly behavior”.Langmuir,2008,24, 4647-4654.
(2)Jinlin He, Peihong Ni*, Cuicui Liu. “Synthesis and characterizationof amphiphilic fluorinated pentablock copolymers based on Pluronic F127”.J. Polym. Sci., Part A: Polym. Chem.,2008,46, 3029-3041.
(1)何金林,顾子旭,梁骏,倪沛红*, “壳聚糖接枝PDMAEMA共聚物的聚集行为”.高分子材料科学与工程,2008,24(12), 126-129.
已获授权发明专利:
(1)何金林, 晏雪生, 倪沛红, 戴礼兴, 徐俊, 张明祖, “一种八臂杂臂星形聚合物的制备方法”, 中国发明专利:ZL 1.7(授权公告日:2021年3月2日)
(2)何金林,鞠鹏飞,李飞, 胡健, 倪沛红, 张明祖, “基于聚二硫醚和聚磷酸酯的还原敏感型共聚物及其制备方法与应用”, 中国发明专利:ZL 8.3(授权公告日:2020年6月2日)
(3)何金林, 晏雪生, 倪沛红, 戴礼兴, 徐俊, 张明祖, “一种八臂杂臂星形聚合物及其制备方法”, 中国发明专利:ZL .2(授权公告日:2019年3月1日)
(4)倪沛红, 何金林, 王赛, 张明祖, “生物可降解的温度/pH双重响应性水凝胶”, 中国发明专利:ZL2.2. (授权公告日:
(5)倪沛红, 刘洁, 何金林, 张明祖, “基于阿霉素前药和基因共载的混合胶束药物及其制备方法”, 中国发明专利:ZL 2.1(授权公告日:2021年3月2日)
(6)倪沛红, 李磊, 何金林, 张明祖, “基于两性离子及叶酸靶向的酸敏感性阿霉素前药及其制备方法与应用”, 中国发明专利:ZL 3.1(授权公告日:2020年5月22日)
(7)倪沛红, 董淑祥, 何金林, 张明祖, 孙月, 刘洁, “同时键合喜树碱和阿霉素的聚磷酸酯前药及其制备方法与应用”, 中国发明专利:ZL 5.7(授权公告日:2020年1月14日)
(8)倪沛红, 杜雪琼, 何金林, 张明祖, “还原/pH双重响应性阿霉素前药及其制备方法与应用”, 中国发明专利:ZL 7.7(授权公告日:2019年10月29日)
(9)张明祖, 胡健康, 何金林, 倪沛红, “一种具有互穿网络结构的多孔性锂离子电池隔膜的制备方法”, 中国发明专利:ZL 7.1(授权公告日:2018年9月25日)
(10)倪沛红, 胡健, 何金林, 张明祖, “基于聚磷酸酯的叶酸靶向酸敏感核交联载药胶束”, 中国发明专利:ZL 1.1(授权公告日:2018年9月25日)
(11)张明祖, 吴大钊, 何金林, 倪沛红, “一种复合锂离子电池隔膜及其制备方法”, 中国发明专利:ZL 1.2(授权公告日:2017年3月22日)
(12)倪沛红, 胡健, 何金林, 张明祖, “基于聚磷酸酯的叶酸靶向酸敏感核交联载药胶束及其制备方法”, 中国发明专利:ZL 3.0(授权公告日:2017年3月29日)
(13)倪沛红, 王海蓉, 何金林, 张明祖, 李飞, 陶云锋, “基于聚乙二醇的酸敏感性阿霉素前药及其制备方法与应用”, 中国发明专利:ZL 2.4(授权公告日:2016年2月17日)
(14)倪沛红, 陶云锋, 何金林, 张明祖, “一种基于聚磷酸酯的无规共聚物、其制备方法及应用”, 中国发明专利:ZL 4.0(授权公告日:2016年2月3日)
(15)倪沛红, 郝莹, 张明祖, 何金林, “酸敏感阳离子型嵌段共聚物及其制备方法与应用”, 中国发明专利:ZL 9.8(授权公告日:2015年9月23日)
(16)倪沛红, 胡健, 何金林, 张明祖, “酸敏感两亲性星状嵌段共聚物、其制备方法及应用”, 中国发明专利:ZL 1.1(授权公告日:2015年9月23日)
(17)倪沛红, 王海蓉, 何金林, 张明祖, 李飞, 陶云锋, “具有酸敏感性的两亲性三嵌段共聚物、其制备方法及应用”, 中国发明专利:ZL 0.0(授权公告日:2015年5月27日)
(18)倪沛红, 郝莹, 何金林, 张明祖, 刘坚, 张洋, “阳离子型刷形嵌段共聚物、其制备方法及应用”, 中国发明专利:ZL 6.7(授权公告日:2014年9月17日)
(19)倪沛红, 邵海燕,何金林,李阳,张明祖,“侧链功能化修饰的生物可降解型两亲性聚酯”, 中国发明专利:ZL 8.4(授权公告日:2012年7月19日)
(20)倪沛红, 刘旭, 何金林, 张明祖, 朱秀林, “pH/温度响应的双亲水性嵌段共聚物及其制备方法”,中国发明专利:ZL 2009 1 **.3(授权公告日:
研究领域
(1)拓扑结构高分子及热塑性弹性体的合成,活性负离子聚合;
(2)生物可降解高分子(聚磷酸酯、脂肪族聚酯、葡聚糖、透明质酸等)的合成及功能化修饰。
(1) Synthesis of functional topological polymers and thermoplastic elastomer; High vacuum living anionic polymerization;
(2) Synthesis and functional modification of biodegradable polymers including polyphosphoesters, aliphatic polyesters, dextran,hyaluronic acid, etc.
基本信息
何金林
职称:副教授
院部/部门:材料与化学化工学部
学历:博士
学位:研究生
毕业学校:苏州大学
毕业专业:高分子化学与物理
联系方式
通讯地址:苏州市工业园区仁爱路199号苏州大学独墅湖校区
邮政编码:215123
电子邮箱:jlhe@suda.edu.cn
联系电话:
传真号码:
办公地点:材料与化学化工学部912楼706室
科学研究
倪沛红教授课题组现有成员15人,其中,教师3名(倪沛红教授、张明祖副教授、何金林副教授)、硕士研究生12名。
本课题组主要研究方向为高分子合成化学及功能高分子材料的合成与应用。课题组在国内较早开展氧阴离子引发聚合体系研究,拓展该类聚合方法的单体适用范围,利用该方法制备了多种线形、超支化、星状-嵌段形氟碳-碳氢杂化的刺激响应性两亲共聚物;研究它们在溶液中的自组装行为,并以所合成的两亲性共聚物作为大分子乳化剂,通过(细)乳液聚合,成功获得表面功能化的聚合物微球。近年来,课题组着重于结合多种聚合方法(如活性阴离子聚合、可控/“活性”自由基聚合、开环聚合等)与高效有机化学反应(如“Click”化学),合成具有各种特殊性能的新型功能高分子材料(例如:温度/pH敏感、氧化还原敏感、磁响应性、荧光特性等),并尝试将生物相容和生物可降解的聚合物用作非病毒基因载体和药物载体等。另一方面,课题组积极与企业界开展合作研究,在功能性聚合物涂层、水泥减水剂、微胶囊的制备和应用、改性锂离子电池隔膜、含氟功能性聚合物乳液等领域有比较广泛的合作。2005年以来,课题组先后承担国家自然科学基金项目5项、江苏省自然科学基金项目6项、企业合作项目多项。已在国内外专业期刊发表论文100余篇,其中包括Macromolecules、Soft Matter、Langmuir、Polymer Chemistry、Polymer、J. Mater. Chem. B等;撰写英文著作3章;获授权中国发明专利20项。
科研团队
隶属于倪沛红教授科研团队一员。
论文
荣誉奖励
1、2018 J. Mater. Chem. B Emerging Investigator
2、2014、2015、2017、2018、2019年度苏州大学教职工年度考核优秀
3、2010年国际高分子化学学术讨论会(PC2010)—“优秀墙报奖”
4、2010年江苏省博士生学术论坛(化学与绿色化工)—“优秀论文奖”
5、苏州大学“课程思政”课堂教学竞赛,2019年7月10日,三等奖
6、2020年本科毕业设计(论文)优秀指导教师,苏州大学,2020年06月
7、苏州大学第十九届青年教师课堂教学竞赛,苏州大学,2020年10月,二等奖
开授课程
本科课程
1.《基础化学》通识课程
2.《粘合剂与涂料》专业选修课
3.《化工基础实验》
招生信息
以研究团队为单位,招收化学、材料、生物功能材料、化工等专业本科和研究生。欢迎对课题组感兴趣的同学前来交流,课题组接收本科生参与申请大学生创新创业训练计划项目。
研究项目(旧版)
荣誉奖励(旧版)