个人简介
2012-迄今苏州大学副教授
2010-2012美国宾州州立大学Prof. Gong Chen课题组博士后
2008-2010日本名古屋大学Prof.RyojiNoyori（诺贝尔化学奖获得者）课题组博士后
2003-2008武汉大学雷爱文教授课题组博士1999-2003西南大学本科



研究领域
1.碳氢键官能团转化，碳氧键活化；
2.小分子（CO，CO2，NO，O2等）活化；
3.天然产物和生物活性分子半合成。




基本信息
赵应声
职称： 副教授
院部/部门： 材料与化学化工学部
学历：
学位：
毕业学校：
毕业专业：


联系方式
通讯地址：
邮政编码：
电子邮箱： yszhao@suda.edu.cn
联系电话： **
传真号码：
办公地点： 材料与化学化工学部




Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持




科学研究




科研团队



Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持




论文
1.Yuan, C.; Zhu. L; Lan, Y*.;Zhao. Y*.;Ruthenium(II)-catalzyedC-H Difluoromethylation of Ketoxime: Tunning the Regioselectivity frommetatoparaPosition;Angew.Chem. Int. Ed.2018,DOI: 10.1002/anie.
2.Yuan C., Zhu L., Yang Y., Lan, Y., Zhao. Y.,* Ruthenium(II)-enabledpara-Selective C-H Difluoromethylation of Anilides, Indolines andTetrahydroquinolines;Nat. Commun.2018,Accepted
3.Zhu, Y.; Chen, X.; Yuan, C.; Li, G.; Zhang, J.;Zhao, Y*., Pd-catalysed ligand-enabledcarboxylate-directed highly regioselective arylation of aliphatic acids.Nat. commun.2017,8, 14904.
4.Wang, C.; Chen, C.; Zhang, J.; Han, J.; Wang, Q.; Guo,K.; Liu, P.; Guan, M.; Yao, Y*.;Zhao,Y.*,Easily Accessible Auxiliary for Palladium-Catalyzed IntramolecularAmination of C(sp2)?H and C(sp3)?H Bonds at δ- and ε-Positions.Angew. Chem. Int. Ed.2014,53(37), 9884-9888.
5.Li, G.; Li, D.; Zhang, J.; Shi, D.-Q.*;Zhao, Y.*, Ligand-Enabled Regioselectivity inthe Oxidative Cross-coupling of Arenes with Toluenes and Cycloalkanes UsingRuthenium Catalysts: Tuning the Site-Selectivity from the ortho to metaPositions.ACS Catal.2017,7(6), 4138-4143.
6.Wang, C.; Zhang, L.; Chen, C.; Han, J.; Yao, Y*.;Zhao, Y. *, Oxalyl amide assisted palladium-catalyzed synthesis ofpyrrolidones via carbonylation of [gamma]-C(sp3)-H bonds of aliphatic aminesubstrates.Chem. Sci.2015,6(8), 4610-4614.
7.Wang, Q.; Han, J.; Wang, C.; Zhang, J.; Huang, Z.; Shi,D.*;Zhao, Y.*, Highly site-selective sequential alkenylation of oxalylamide protected phenylpropylamine derivatives via a seven-memberedpalladacycle.Chem. Sci.2014,5(12), 4962-4967.


9.Yuan, C.; Tu, G.;Zhao,Y.*, Rhodium(III)-Catalyzed Selective Monoarylation of beta or gammaC(sp3)-H Bonds Assisted by a Trimethylpyrazole Group.Org. Lett.2017,19(2), 356-359.
10.Chen, C.; Guan, M.; Zhang, J.; Wen, Z.*;Zhao, Y.*, Palladium-Catalyzed Oxalyl Amide Directed Silylation andGermanylation of Amine Derivatives.Org. Lett.2015,17(15), 3646-3649.
11.Guo, K.; Chen, X.; Guan, M.;Zhao, Y.*,Direct ortho-C–H Functionalization of Aromatic AlcoholsMasked by Acetone Oxime Ether via exo-Palladacycle.Org. Lett.2015,17(7), 1802-1805.
12.Han, J.; Liu, P.; Wang, C.; Wang, Q.; Zhang, J.; Zhao,Y.; Shi, D.; Huang, Z.*;Zhao, Y.*, Oxalyl Amide AssistedPalladium-Catalyzed Arylation of C(sp2)–H Bond at the δ Position.Org.Lett.2014,16(21),5682-5685.
13.Hu, J.; Li, G.; Yuan, C.; Huang, Z.-B.; Shi, D.-Q.*;Zhao,Y.*, Rhodium(III)-CatalyzedOxidative C–H/C–H Cross-Coupling of Heteroarenes and Masked Benzylamines.Org.Lett.2016,18(23),5998-6001.
14.Chen, X.; Han, J.; Zhu, Y.; Yuan, C.; Zhang, J.*;Zhao,Y.*,Transformation of masked benzyl alcohols to o-aminobenzaldehydesthrough C-H activation: a facile approach to quinazolines.Chem. Commun.2016,52(67), 10241-10244.
15.Guan, M.; Chen, C.; Zhang, J.; Zeng, R.*;Zhao,Y.*,Palladium-catalyzed oxalyl amide assisted direct ortho-alkynylation ofarylalkylamine derivatives at positions.Chem. Commun.2015,51(60), 12103-12106.
16.Guan, M.; Pang, Y.; Zhang, J.;*Zhao, Y*., Pd-Catalyzedsequential [small beta]-C(sp3)-H arylation and intramolecular amination of bondsfor synthesis of quinolinones via an N,O-bidentate directing group.Chem.Commun.2016,52(43), 7043-7046.
17.Han, J.; Zhang, L.; Zhu, Y.; Zheng, Y.; Chen, X.; Huang,Z.-B.; Shi, D.-Q*.;Zhao, Y*., Highly regioselective metaarylation of oxalyl amide-protected [small beta]-arylethylamine via theCatellani reaction.Chem. Commun.2016,52(42), 6903-6906.
18.Chen, C.; Wang, C.; Zhang, J.;Zhao, Y.*, Palladium-Catalyzed ortho-Selective C–H Fluorination ofOxalyl Amide-Protected Benzylamines.J. Org. Chem.2015,80(2), 942-949.
19.Han, J.,Y. Zhao,*D. Shi*, Ruthenium-Catalyzed Carbonylation of Oxalyl Amide-Protected Benzylamineswith Isocyanate as the Carbonyl Source.J. Org. Chem.2017. 10.1021/acs.joc.7b00975
20.Han, J.; Zheng, Y.; Wang, C.; Zhu, Y.; Huang, Z.-B.; Shi,D.-Q.; Zeng, R.*;Zhao, Y.*,Pd-Catalyzed Coupling ofγ-C(sp3)–H Bonds of Oxalyl Amide-Protected Amino Acids with Heteroaryl and ArylIodides.J. Org. Chem.2016,81(13), 5681-5689.
21.Han, J.; Zheng, Y.; Wang, C.; Zhu, Y.; Shi, D.-Q.; Zeng,R.*; Huang, Z.-B.*;Zhao, Y. *, Palladium-Catalyzed Oxalyl Amide-Directed γ-Arylationof Aliphatic Amines.J. Org. Chem.2015,80(18),9297-9306.
22.Hu, J.; Guan, M.; Han, J.; Huang, Z.-B.; Shi, D.-Q.*;Zhao,Y*., Palladium-Catalyzed ortho-Olefination of Phenyl Acetic and PhenylPropylacetic Esters via C–H Bond Activation.J. Org. Chem.2015,80(16), 7896-7904.
23.Zhang, L.; Wang, C.; Han, J.; Huang, Z.-B.*;Zhao,Y.*, Palladium-CatalyzedCarbonylation of β-Arylethylamide Directed by Oxalyl Amide in the Presence ofCarbon Monoxide.J. Org. Chem.2016,81(12), 5256-5262.
24.Hu, J.; Li, G.; Huang, Z.-B.; Zhang, J.; Shi, D.-Q.*;Zhao,Y.*, Pd-Catalyzed thiophenedirected regioselective functionalization of arenes: a direct approach tomultiply-substituted benzyl amines.Org. Chem. Front.2017.DOI: 10.1039/c7qo00236j
25.Li, G.; Liu, P.; Zhang, J.; Shi, D.-Q.*;Zhao,Y.*, Palladium-catalyzed direct ortho-alkynylation of arylalkylacidderivatives at γ and δ positions via an N,O-bidentate directing group.Org.Chem. Front.2017.DOI:10.1039/c7qo00327g
26.Guo, K.; Chen, X.; Zhang, J.;Zhao, Y.*,Palladium(II)-Catalyzed Acetoxime Directed ortho-Arylation of AromaticAlcohols.Chem. Eur. J.2015,21(48), 17474-17478.
27.Wang, C.; Chen, C.; Han, J.; Zhang, J.; Yao*, Y.;Zhao, Y.*,Insight into O2-Promoted Base-Catalyzed N-Alkylation ofAmines with Alcohols.Eur. J. Org. Chem.2015,2015(13), 2972-2977.
28.Zhang, L.; Huang, Z.-B.*;Zhao, Y.*, Ru-Catalyzed selective C-H oxidativeolefination with N-heteroarenes directed by pivaloyl amide.Org. Chem.Front.2016, 3 (10), 1271-1275.
29.Han, J.,Y. Zhao*,D. Shi*, Pd-Catalyzed Regioselectively Sequential Meta-,Ortho-C–HFunctionalization of Arenes: A Predictable Approach to SynthesisPolysubstituted β-Arylethylamines.Org. Bio. Chem.2017.DOI: 10.1039/C7OB01135K
30.Guan, M.; Wang, C.; Zhang, J.*;Zhao, Y.,*Practical organic solvent-freeCu(OAc)2 catalyzed aldehyde and imine formation from alcohols under airatmosphere.RSC Adv.2014,4(90), 48777-48782.
31.Liu, P.; Han, J.; Chen, C. P.; Shi, D. Q.*;Zhao, Y*., Palladium-catalyzed oxygenation of C(sp2)-H and C(sp3)-H bondsunder the assistance of oxalyl amide.RSC Adv.2015,5(36), 28430-28434.
32.Liu, P.; Han, J.; Wang, Q.; Huang, Z.; Shi, D.; Zeng, R*.;Zhao, Y.*, Palladium(ii)-catalyzed Sequential ortho-olefination of[small beta]-arylethamines with assistance of oxalyl amide.RSC Adv.2015,5(74), 60646-60649.
33.Wang, C.; Han, J.,Zhao,Y.*Recent Development in N-Auxilixary-Assisted Intramolecular Aminationfor Amine Substrates.Synlett2015,26(08), 997-1002.
34.郑永祥、韩健、黄志斌、史达清*、赵应声*.,草酰胺导向下钯催化的C(sp2)-H和C(sp3)-H键的直接酰氧基化反应.有机化学2017. 37, 2028-2033
35.周盼盼管明玉张静宇*徐凡*赵应声*钯催化分子内胺化合成苯并噁嗪酮衍生物.有机化学2017. 37, 2066-2072.
36.Pang, Y.; Guan, M., Zeng, R.*;Zhao Y.*, A Practical Approach for theSynthesis of Oxindole and Isatin Derivatives by Pd-Catalyzed IntramolecularAminationOrg. Chem. Front.2017. DOI:10.1039/C7QO00710H
37.Yuan, C.; Chen, X.; Zhang, J.*;Zhao. Y.*; meta-Selective C–Hdifluoromethylation of various arenes with a versatile ruthenium catalyst.Org.Chem. Front.2017. 4, 1867.
38.Chen, C.; Zeng, R.; Zhang, J*.Zhao. Y. *;Ruthenium-CatalyzedDifluoroalkylation of 8 Aminoquinoline Amides at the C5-Position.Eur. J. Org. Chem.2017,DOI: 10.1002/ejoc..
39.Shi, P., Wang, X., Zeng, X.Zhao, Y.*, Zeng, R.*;Palladium/silver reagent-promotedaryl phosphorylation: flexible synthesis ofsubstituted-3-benzylidene-2-(2-(diphenylphosphoryl)-aryl)-isoindolin-1-one.RSC Adv.2017,7, 54277-54280.
博士及博士后期间代表性工作
1.Zhao, Y.; Wang, H.;Hou, X.; Hu, Y.; Lei, A.; Zhang, H.; Zhu, L.,J. Am. Chem. Soc.2006,128, 15048-15049.
2.Zhao,Y.; Jin, L.; Li, P.; Lei, A.,J. Am. Chem. Soc.2008,130(29), 9429-9433.
3.Zhao,Y.; Chen, G.,Org. Lett.2011,13(18), 4850-4853.
4.Zhao,Y.; Foo, S. W.; Saito, S., IAngew. Chem. Int. Ed.2011,50(13), 3006-3009.
5.Zhao,Y.; He, G.; Nack, W. A.; Chen, G.,Org. Lett.2012,14(12), 2948-2951.





...... to be continued



荣誉奖励
1、获得RocheCreative Chemistry Award, Roche R&D Center (China) Ltd.,2007
2、 湖北省优秀博士论文,2009
3、湖北省科学技术奖一等奖,雷爱文，张恒，赵应声，石炜，陈建,2012
4、获得苏州大学东吴****称号,2016
5、Thieme Chemistry Journals Award,2018





Copyright ? 2011-2014苏州大学版权所有苏州大学信息化建设与管理中心技术支持




开授课程
1. 现代有机合成新技术


招生信息
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