任职

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苏州大学药学院药物分析系临床质谱中心

联系方式

苏州市工业园区仁爱路199号苏州大学独墅湖校区二期云轩楼2107室
电话：（0521）6588 0229 （办公室）; 134 0506 4922 （手机）
邮箱：yangs2020@suda.edu.cn

教育背景和研究经历（按时间顺序）：

1990年9月-1994年7月：哈尔滨工业大学应用化学理学学士，中国黑龙江
1994年9月-1997年3月：上海交通大学材料科学与工程硕士，中国上海
2002年1月-2003年7月：新加坡国立大学材料科学硕士，新加坡
2003年8月-2008年12月：马里兰大学帕克分校机械工程博士学位，美国马里兰
2009年1月-2010年12月：马里兰大学帕克分校微流体中心博士后，美国马里兰
2011年1月-2013年9月：约翰霍普金斯大学病理学博士后，美国马里兰
2013年10月-2016年9月：约翰霍普金斯大学病理学青年教师，美国马里兰

工作和科研经历（按时间顺序）：

1994年9月-1997年3月：上海交通大学材料科学与工程研究助理，中国上海
1997年3月-1999年12月：上海哈威新材料技术有限公司质量控制经理，中国上海
2000年1月-2001年12月：中国上海三星第一产业有限公司技术支持工程师，中国上海
2002年1月-2003年7月：新加坡国立大学材料科学系研究助理，新加坡
2003年8月-2008年12月：马里兰大学帕克分校机械工程研究/教学助理，美国马里兰
2009年1月-2010年12月：马里兰大学帕克分校微流体中心博士后，美国马里兰
2011年1月-2013年9月：约翰霍普金斯大学病理学研究员，美国马里兰
2013年10月-2016年9月：约翰霍普金斯大学病理学青年教师，美国马里兰
2016年10月-2019年9月：美国食品药物管理局细菌多糖实验室副研究员，美国马里兰
2019年10月-2020年9月：美国国立卫生研究院生物化学组研究员，美国马里兰

研究活动
奖项和荣誉
2008最佳海报，HPLC 2008药物分析创新奖，马里兰州巴尔的摩
2011年糖生物学学会年会2011年Tavel Award，华盛顿州西雅图
2012年，第14届病理学研究日年度青年研究者奖（2012年），马里兰州巴尔的摩
2012年第11届HUPO世界大会Tavel Award，马萨诸塞州波士顿
2012年演讲奖第三名，2012年第11届HUPO世界大会，马萨诸塞州波士顿
2013年Tavel Award，2013年第22届糖缀合物国际研讨会，中国大连
2017年青年科学家研究奖，ACS Pittcon 2017，CACA，伊利诺伊州芝加哥
2018年FDA CBER科学成就奖，美国FDA，马里兰银泉

教育出版物
章节
1. S.Yang和D. DeVoe，G.Jenkins，C.D。编辑的“通过热塑热压印制造微流体器件”一章。曼斯菲尔德（Mansfield），《分子生物学方法》（Methods in Molecular Biology）中的“微流体诊断”，Humana Press，Springer，2012年。
2. S. Yang和K.Q.江，“弹性体在微系统和微流体中的应用”一章，在“弹性体” 2012年，InTech，203-222。
3. S. Li，S.N. Thomas，H. Zhang和S. Yang，“通过LC-MS（Wiley）进行靶向生物标志物定量”中的“糖蛋白生物标志物”一章，2017年，第246-272页。

专利
2017年6月13日：S. Yang，H. Zhang，约翰霍普金斯大学（Johns Hopkins University）的AutoTip for high-throughput analysis of N-glycans，待批。
2015年10月12日：S. Li，S. Yang和H. Zhang，Quaternary amine containing isobaric tag for quantitative glycan profiling。马里兰大学和约翰霍普金斯大学，美国专利号 A1（美国10,254,291 B2）
2014年5月13日：H. Zhang，S. Yang，P. Shah，S. Sun，Solid phase glycan and glycopeptide analysis and microfluidic chip for glycomic extraction, analysis and methods for using same。约翰霍普金斯大学，世界专利号2,014,040,066 A1; US 2015/** A1。
2014年3月13日：H. Zhang，S. Yang，Shuwei Li，Isobaric aldehyde-reactive tags for and analysis of glycans using same。约翰霍普金斯大学，世界专利号2,014,040,072 A1; US 2015/** A1（US 99,394,44 B2）。
2012年12月13日：H. Zhang，S. Yang。Glycan and glycopeptide capture and release using reversible hydrazone-based method。约翰霍普金斯大学，世界专利号2,012,170,491; US 2014/** A1。

已发表的论文
https://scholar.google.com/citations?hl=zh_CN&user=sQmBEbsAAAAJ&view_op=list_works&sortby=pubdate
（*通讯作者）
S. Yangand J. F. Cipollo, “A versatile solid-phase method for glycan release via enzymatic and chemical reactions,” revision, 2020.
Q. Wang, T. Wang, S. Yang, C-y. Chung, C-t. Li, J.F. Cipollo, M.J. Betenbaugh, “The interplay of protein engineering and glyco-engineering to generate better-refined antibodies in Chinese hamster ovary cells,” submitted, 2020.
S. Yang*, Y. Wang, Q. Wang, and J.F. Cipollo, “Express cells impact glycosite occupancy and types of glycans on SARS-CoV-2 spike glycoprotein,” submitted to ACS Infectious Diseases, 2020.
H. Yu, J. Wang, Z. Tang, X. Li, M. Yin, F. Zhang, J. Shu, W. Chen, S. Yang, and L. Zheng, “Integrated glycomics strategy for evaluation of glycosylation alterations in salivary proteins associated with type 2 diabetes mellitus,” RSC Advances 2020, accepted.
S. Yang, Y. Wang, M. Mann, Q. Wang, E. Tian, L. Zhang, J.F. Cipollo, K.G.T. Hagen, and L.A. Tabak, “Improved online LC-MS/MS identification of O-glycosites by EThcD fragmentation, chemoenzymatic reaction, and SPE enrichment,” Glycoconjugate Journal 2020, in press.
S. Yang, W.Wu, R-f Shen, J. Sjogren, and J.F. Cipollo, “Optimization of O-GIG for enrichment and release of protein O-glycosylation,” Analytical Chemistry 2020, 92, 10946-10951.
U.H. Mortensen, D.C. Anyaogu, A.H. Hansen, J.B. Hoof, N.I. Majewska, J.T. Paul, K.R. Nielsen, T.J. Hobley, S. Yang, H. Zhang, and M. Betenbaugh, “Glycoengineering of aspergillus nidulans to produce precursors for humanized N-glycan structures,” Metabolic Engineering 2020, revision.
Qiong Wang, Tiexin Wang, S. Yang, S. Sha, W.W. Wu, Y. Chen, J.T. Paul, R-f. Shen, J.F. Cipollo, and Michael J. Betenbaugh, “Metabolic Engineering Challenges to extending N-glycan pathways in Chinese hamster ovary cells,” Metabolic Engineering, 2020, 61, 301-314. (IF: 7.808)
N. de Haan, S. Yang, J.F. Cipollo, and M. Wuhrer, “Glycomics studies using sialic acid derivatization and mass spectrometry,” Nature Reviews Chemistry 2020, 4, 229-242. (IF: 34.953)
Maira Lorna A. De Leoz et al., “NIST interlaboratory study on glycosylation analysis of monoclonal antibodies: comparison of results from diverse analytical methods,” Molecular Cellular Proteomics 2020, 19(1), 11-30. (IF: 5.41)
C. Chung, Q. Wang, S. Yang, S. Chough, J.F. Cipollo, J.P. Balthasa, and M.J. Betenbaugh, “The impact of sialylation linkages of the recombinant butyrylcholinesterases on their pharmacokinetics,” Biotechnology and Bioengineering 2019, 117(1), 157-166. (IF: 4.260)
H. Wan, J. Gao, H. Yang, S. Yang, R. Harvey et al., “A Neuraminidase Antigenic Drift Contributed to Recent Low Effectiveness of H3N2 Influenza Vaccine,” Nature Microbiology 2019, 4, 2216-2225.
S. Yang, Z. Yang, P. Wang, “Bioanalysis for precision medicine”, Bioanalysis 2019, 11(11), 1039-1043. (IF: 2.673)
S. Yang*, P. Onigman, W. Wu, J. Sjogren, H. Nyhlen, R-F. Shen, and J. Cipollo, “Deciphering protein O-glycosylation: solid-phase chemoenzymatic cleavage and enrichment,” Analytical Chemistry 2018, 90(13), 8261-8269 (ACS Editor’s Choice). (IF: 6.320)
S. Yang*, W. Wu, R-F. Shen, M. Bern, and J. Cipollo, “Identification of sialic acid linkages on intact glycopeptides via differential chemical modification using intactGIG-HILIC,” Journal of the American Society for Mass Spectrometry 2018, 29(6), 1273. (IF: 2.786)
S. Yang*, S. Chatterjee, and J. Cipollo, “The glycoproteomics-mass spectrometry for studying cardiac hypertrophy and heart failure,” Proteomics-Clinical Applications 2018, 12(5), **. (IF: 3.841)
N. Hoti, S. Yang, Y. Hu, P. Shah, M. Haffner, and H. Zhang, “Overexpression of α(1,6) fucosyltransferase in the development of castration resistant prostate cancer,”Prostate Cancer and Prostatic Diseases 2018, 21(1), 137. (IF: 4.600)
W. Zhou, S. Yang, P.G. Wang, “Matrix effects and matrix effect factors,” Bioanalysis 2017, 9(23), 1839. (IF: 2.673)
S. Yang*et al., “High-throughput analysis of N-glycans using AutoTip via glycoprotein immobilization for glycan extract,” Scientific Reports 2017,7(1), 10216. (IF: 4.259)
S. Yang*, L. Chen, D.W. Chen, Q. Li, and H. Zhang, “Protein signatures of molecular pathways in non-small cell lung carcinoma (NSCLC): comparison of glycoproteomics and global proteomics,” Clinical Proteomics 2017,14(1), 31. (IF: 3.476)
S. Yang, E. Jankowska, M. Kosikova, H. Xie, and J. Cipollo, “Sialic acid linkage analysis of influenza virus glycoproteins using solid-phase chemical modification,” Analytical Chemistry 2017, 89(17), 9508. (IF: 6.320)
N. Hoti, S. Yang, P. Aiyetan, B. Kumar, P. Shah, T. Johnson, W.H. Chowdery, H. Zhang, and R. Rodriguez, “Overexpression of Exportin-5 overrides the inhibitory effect of miRNAs regulation control in prostate cancer and stabilizes proteins via post-translational modifications,” Neoplasia 2017, 19(10), 817. (IF: 5.006)
S. Yangand P. Wang, “Method development of glycoprotein biomarkers for cancers,” Bioanalysis 2017; 9(12):903. (IF: 2.673)
C. Chung, Q. Wang, S. Yang, S.A. Ponce, B.J. Kirsch, H. Hang, M.J. Betenbaugh, “Combinatorial genome and protein engineering yields monoclonal antibodies with hypergalactosylation from CHO cells,” Biotechnology and Bioengineering 2017, 114(12), 2848-2856. (IF: 4.481)
S. Yang*, L. Zhang, S. Thomas, Y. Hu, S. Li, J. Cipollo, and H. Zhang, “Modification of sialic acids on solid-phase: accurate characterization of protein sialylation,” Analytical Chemistry 2017, 89(12), 6330-6335. (IF: 6.320)
S. Yang*, Y. Hu, L. Sokoll, and H. Zhang, “Quantitative analysis of glycans using a solid-phase method”, Nature Protocols 2017, 12(6), 1229-1244. (IF: 10.032)
S. Yang*, N. Hoti, W. Yang, Y. Liu, S. Li, and S. Zhang, “Simultaneous analyses of N-linked and O-linked glycans using solid-phase chemoenzymatic method,” Clinical Proteomics 2016; 14 (3):1. (IF: 3.476)
C. Chung, Q. Wang, S. Yang, B. Yin, H. Zhang, M. Betenbaugh, “Integrated Genome and Protein Editing Swaps α‐2, 6 Sialylation for α‐2, 3 Sialic Acid on Recombinant Antibodies from CHO, ” Biotechnology Journal 2017; 12(2):**. (IF: 3.446)
N. Hoti, P. Shah, Y. Hu, S. Yang, and H. Zhang, “Proteomics analyses of prostate cancer cells reveals cellular pathways associated with androgen resistance,” Proteomics 2017, 17, 6. (IF: 4.041)
D. Do, S. Yanget al., “N-glycan in cockroach allergen regulates human basophil function,” Immunity, Inflammation and Disease 2017; 5(4):386.
X. Jia, J. Chen, S. Sun, W. Yang, S. Yang, P. Shah, N. Hoti, B. Veltri, and H. Zhang, “Detection of Aggressive Prostate Cancer-Associated Glycoproteins in Urine using Glycoproteomics and Mass Spectrometry,” Proteomics 2016; 16(23):2928. (IF: 4.041)
S. Yang, M. Wang, L. Chen, B. Yin, G. Song, I.V. Turko, K.W. Phinney, M.J. Betenbaugh, H. Zhang, and S. Li, “QUANTITY: an isobaric tag for quantitative glycomics,” Scientific Reports, 2015; 5:17585. (IF: 4.259)
P. Shah, X. Wag, W. Yang, S.Toghi Eshghi, S. Sun, N. Hoti, L. Chen, S. Yang, J. Pasay, A. Rubin, and H. Zhang, “Integrated proteomic and glycoproteomic analyses of prostate cancer cells reveals glycoprotein alteration in protein abundance and glycosylation,” Molecular & Cellular Proteomics 2015; 14(10):2753. (IF: 6.540)
B. Yin, Y. Gao, C. Chung, S. Yang, E. Blake, M.C. Stuczynski, J. Tang, H.F. Kildegaard, M.R. Anderson, H. Zhang, and M.J. Betenbaugh, “Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N-glycan branching and sialylation,” Biotechnology and Bioengineering 2015; 112 (11):2343. (IF: 4.481)
S. Yang*, A. Rubin, S. Toghi Eshghi, and H. Zhang, “N-linked glycoproteins: isolation, identification, and quantitation,” Proteomics 2015; 16:241. (IF: 4.041)
S. Yang, S. Mishra, L. Chen, J. Zhou, D.W. Chan, S. Chatterjee, and H. Zhang, “An integrated glycoprotein immobilization method for glycopeptide and glycan analysis of cardiac hypertrophy,” Analytical Chemistry 2015; 87(19):9671. (IF: 6.320)
S. Sun, P. Shah, S. Toghi Eshghi, W. Yang, N. Trikannad, S. Yang, L. Chen, P. Aiyetan, N. Hoti, Z. Zhang, D.W. Chan, and H. Zhang, “Solid-phase extraction of N-linked glycans and glycosite-containing peptides (NGAG) for comprehensive characterization of glycoproteins,” Nature Biotechnology 2016; 34(1):84. (IF: 41.667)
P. Shah, B. Zhang, C. Choi, S. Yang, J. Zhou, R. Harlan, Y. Tian, Z. Zhang, D.W. Chan, and H. Zhang, “Tissue proteomics using chemical immobilization and mass spectrometry,” Analytical Biochemistry 2015; 469:27. (IF: 2.219)
S. Yang*, L. Chen, P. Shah, W. Yang, B. Zhang, Z. Zhang, D.W. Chan, D.A. Kass, J.E. Eyk, and H. Zhang, “Glycoproteins identified from heart failure and treatment models,” Proteomics 2014; 14:17. (IF: 4.041)
S. Toghi Eshghi, S. Yang, X. Wang, P. Shah, X. Li, and H. Zhang, “Imaging of N-linked glycans from formalin-fixed paraffin-embedded tissue sections using MALDI mass spectrometry,” ACS Chemical Biology 2014; 9(9): 2149. (IF: 4.995)
W. Yang, P. Shah, S. Toghi Eshghi, S. Yang, S. Sun, M. Ao, A. Rubin, J. Jackson, and H. Zhang, “Glycoform-analysis of recombinant and human deficiency virus envelope protein gp120 via higher energy C-trap dissociation and spectral-aligning strategy,” Analytical Chemistry 2014; 86(14):6959. (IF: 6.320)
S. Yangand H. Zhang, “Glycomic analysis of glycans released from glycoproteins using chemical immobilization and mass spectrometry,” Current Protocols in Chemical Biology 2014; 6:191. (IF: 7.889)
S. Yang, S. Toghi Eshghi, H. Chiu, D.L. DeVoe, and H. Zhang, “Glycomic analysis by glycoprotein immobilization for glycan extraction and liquid chromatography on microfluidic chip,” Analytical Chemistry 2013; 85(21): 10117. (IF: 6.320)
S. Yang, W. Yuan, W. Yang, J. Zhou, R. Harlan, J.L. Edwards, S. Li, and H. Zhang, “Glycan analysis by isobaric aldehyde reactive tags and mass spectrometry,” Analytical Chemistry 2013; 85(17):8188. (IF: 6.320)
S. Yang, Y. Li, P.K. Shah, and H. Zhang, “Glycomic analysis using glycoprotein immobilization for glycan extraction,” Analytical Chemistry 2013; 85(11):5555. (IF: 6.320)
P.K. Shah, S. Yang, S. Sun, P. Aiyata, K.J. Yarema, and H. Zhang, “Mass spectrometric analysis of sialylated glycans using solid phase labeling of sialic acids,” Analytical Chemistry 2013; 85(7): 3606. (IF: 6.320)
S. Yang, and H. Zhang, “Solid-phase glycan isolation for glycomics analysis,” Proteomics: Clinical Applications 2012; 6(11-12): 596. (IF: 3.841)
P. Hareesh, I. Misri, S. Yang, D.L. DeVoe, “Transverse integrated electrode actuation of homogenous bulk PZT,” IEEE/ASME Journal of Microelectromechanical Systems 2012; 21(6): 1513. (IF: 2.124)
I. Misri, P. Hareesh, S. Yang, D.L. DeVoe, “Microfabrication of bulk PZT transducers by dry film photolithography and micro powder blasting,” Journal of Micromechanics and Microengineering 2012; 22: 085017. (IF: 1.731)
S. Yangand H. Zhang, “Glycan analysis by reversible reaction to hydrazide beads and mass spectrometry,” Analytical Chemistry 2012; 84: 2232. (IF: 6.320)
J. Liu, J. Chen, S. Yang, C.C. Zhang, and D. DeVoe, “Mixed-mode electrokinetic and chromatographic peptide separations in a microvalve-integrated polymer chip,” Lab on a Chip 2010; 10: 2122. (IF: 6.000)
S. Yang, J. Wu, and M. Pecht, “Reliability assessment of land grid array sockets subjected to mixed flowing gas environment,” IEEE Transactions on Reliability 2009; 58: 634.(IF: 2.790)
S. Yangand D. DeVoe, “Microfluidic two-dimensional IEF-CZE for proteomics,” Proceedings of International Solid-State Sensors, Actuators and Microsystems Conference, Transducers 2009, Denver, CO, Jun 21-25, 2009.
S. Yang, J. Liu, C.S. Lee, and D. DeVoe, “Microfluidic 2-D PAGE using multifunctional in-situ polyacrylamide gels and discontinuous buffers,” Lab on a Chip 2009; 9: 592. (IF: 6.000)
S. Yang, J. Liu, and D. DeVoe, “Spatially-multiplexed protein separations enabled by multifunctional photopolymerized gels,” Proceedings of the 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2008), San Diego, CA, Oct 12-16, 173-175.
J. Liu, S. Yang, C.S. Lee, and D. DeVoe, “Polyacrylamide gel plugs enabling 2-D microfluidic protein separations via IEF and multiplexed SDS gel electrophoresis,” Electrophoresis 2008; 29(11): 2241. (IF: 3.028)
S. Yang, J. Liu, and D. DeVoe, “Optimization of sample transfer in two-dimensional microfluidic separation systems,” Lab on a Chip 2008, 8, 1145-1152. (IF: 6.000)
S. Yang, and A. Christou, “Failure model for silver electrochemical migration,” IEEE Transactions on Device and Materials Reliability 2007; 7 (1): 188. (IF: 1.575)
S. Yang, J. Wu, D. Tsai, and M. Pecht, “Contact resistance estimation for time-dependent silicone elastomer matrix of land grid array socket,” IEEE Transactions on Components and Packaging Technologies 2007; 30(1): 81. (IF: 1.581)
S. Yang, J. Wu, and A. Christou, “Initial stage of silver electrochemical migration degradation,” Microelectronics Reliability 2006; 46: 1915. (IF: 1.371)
J.S. Buch, J. Liu, S. Yang, C.-W. Tsao, T. Song, P. Sivanesan, K. Phalnikar1, C.S. Lee, and D.L. DeVoe, “Automated two-dimensional microfluidic protein profiling combining IEF and SDS gel electrophoresis,” Proceedings of 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2006), Tokyo, Japan, Nov 5-9, 1579-1581.
S. Yang, J. Wu, and M. Pecht, “Electrochemical migration of land grid array sockets under highly accelerated stress conditions,” Proceedings of 51st IEEE Holm Conference, Chicago, IL, Sep 26-29, 2005, 238-244.
S. Yang, Y-W Zhang, and K. Zeng, “Analysis of nanoindentation creep for polymeric materials,” Journal of Applied Physics 2004; 95 (7): 3655. (IF: 2.068)
S. Yang, K. Sun, R. Wu, “Research on damping property of hybrid fiber composites,” Fiber Composites 2002; 19(1): 6 (Chinese). (IF: 0.464)
S. Yang, K. Sun, R. Wu, “Research on E-51 epoxy curing system,” Fiber Reinforced Plastics/Composites 2002; 2: 32 (Chinese). (IF: 1.503)
S. Yang, K. Sun, R. Wu, “Relationships between parameter design and mechanical properties of hybrid composites,” Fiber Composites 2001; 18(4): 14 (Chinese). (IF: 0.464)


正在准备的论文
Q. Wang, S. Yang, T. Wang, L. Parsons, W. Wu, M.J. Betenbaugh, J.F. Cipollo, “Advanced N- and O-glycosylation characterization of multiple Chinese hamster ovary host cell lines using HILIC-GIG method,” in preparation.
S. Yang, W.Wu, R-F Shen, and J.F. Cipollo, “A microscale O-glycan isolation by β-elimination and permethylation,”in preparation.
S. Yang, F. Assis, W.Wu, J. Sjogren, L. Parsons, H. Nyhlen, P. Onigman, R-f Shen, M. Rios, and J.F. Cipollo, “Glycosylation migration in Zika virus strains from 1947 to 2016 using a novel lectin solid-phase enrichment,” in preparation.
S. Yang, H. Wan, M. Eichelberger, Z. Ye, and J. Cipollo, “Interaction of different influenza virus neuraminidases on removal of specific sialic acids from sialyl-glycoproteins,” preparing for ACS Infectious Disease 2020.
C. Chuang, Q. Wang, S. Yang, J. Cipollo, M. Betenbaugh, “Glycoengineering on IgG antibody,” preparing for Biotechnology and Bioengineering.
S. Yang, W. Wu, M. Kosikova, X. Hang, R-f. Shen, and J. Cipollo, “Sialic linkage migration in cell passage: an indication to cell virus infectivity,” preparing for Journal of Virology.

墙报和大会报告1
2020/6/3, Metabolic engineering challenges to extending N-glycan pathways in CHO cells, 68^thASMS ASMS Conference on Mass Spectrometry and Allied Topics, Houston, TX.
2020/6/2, Comprehensive N- and O-glycosylation characterization of multiple CHO host cell lines using HILIC-GIG method, 68^thASMS ASMS Conference on Mass Spectrometry and Allied Topics, Houston, TX.
2019/7/8, GlycoCatch lectin for comprehensive analysis of protein glycosylation, 2019 NIH&FDA Glycoscience Research Day, Bethesda, MD.
2019/6/2-6, Analysis of Zika Viral Polyprotein N- and O-glycosylation Using a Novel Lectin-chemoenzymatic Enrichment, 67^thASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, GA.
2018/8/19-23, Host ANAL DIVISION session on “solid-phase chemoenzymatic for glycosylation analysis”, 256^thACS Fall National Meeting, Boston, MA. (oral)
2018/7/13, Solid-phase chemoenzymatic method for cleavage and enrichment of protein O-glycosylation, NIH/FDA Glycoscience Research Day, Bethesda, MD. (oral)
2018/6/3-7, Deciphering complex O-glycosylation: solid-phase chemoenzymatic cleavage and enrichment, 66^thASMS Conference on Mass Spectrometry and Allied Topics, San Diego, CA.
2018/6/3-7, “A mass spectrometry based glycomics platform for analysis of influenza vaccines,” 66^thASMS Conference on Mass Spectrometry and Allied Topics, San Diego, CA.
2018/5/6-11, Tailoring antibody glycosylation via integrating genome and protein engineering to generate preferred glycoforms on the Fc region, Cell Culture Engineering XVI, Tampa, FL. (oral)
2017/08/20-24, Sialic acid modification: stabilization and determination of linkages of sialylated glycans, 254th American Chemical Society National Meeting & Exposition, Washington DC. (oral)
2017/6/4-9, Identification of sialic acid linkages using esterification on solid-phase, 65^thconference on Mass Spectrometry and Allied Topics, Indianapolis, IL.
2017/5/5, Identification of sialic acid isomers from influenza virus replications in MDCK cells using solid-phase chemoenzymatic method, 2017 NIH&FDA Glycoscience Research Day, Bethesda, MD. (oral)
2017/03/5-9, Career development often driven by the opportunity and persistence, CACA Pittcon Conference 2017, Chicago, IL (oral)
2016/06/5-9, N-glycan analysis using GIG-automation on sialylglycotransferase knock-in CHO cell line, 64th Conference on Mass Spectrometry and Allied Topics, San Antonio, TX.
2016/06/5-9, QUANTITY: An isobaric tag for quantitative glycomics, 64^thConference on Mass Spectrometry and Allied Topics, San Antonio, TX. (oral)
2016/06/5-9, GPQuest: a free software for identification of glycans and intact glycopeptides, 64^thConference on Mass Spectrometry and Allied Topics, San Antonio, TX.
2016/06/29, Glycan analysis using GIG-automation for biological applications, 2016 NIH&FDA Glycoscience Research Day, Bethesda, MD.
2016/06/23, Quantitative analysis of N-glycans in glycoengineered EPO using QUANTITY, 2016 Biomanufacturing Technology Summit, Rockville, MD.
2016/03/13-16, A novel tandem isobaric tag for quantitative analysis of N-glycans: QUANTITY, US HUPO, Boston, MA. (oral)
2016/03/4-7, A role for glycans in Bla g 2 cockroach allergen-induced allergic responses, 2016 AAAAI Annual Meeting, Los Angeles, CA.
2016/01/15, Signature proteins associated with lung carcinomas, PEG Meeting, Baltimore, MD. (oral)
2015/07/30-31, Glycomic analysis using chemoenzymatic platform, Advanced Mammalian Biomanufacturing Innovation Center NSF I/UCRC Planning Grant Meeting, Mt. Washington, Baltimore, MD.
2015/07/24, Mass spectrometry core: mass spectrometric analyses of glycans, PEG in Glycosciences, Annual Retreat, Mt. Washington, Baltimore, MD. (oral)
2015/05/31-06/04, Glycoproteomic and proteomic analyses of hearts from hypertrophic cardiomyopathy, 63^rdASMS Conference on Mass Spectrometry and Allied Topics, St Louis, MO.
2015/04/17, Regulation of proteins in left-ventricular dyssynchronous heart by cardiac resynchronization therapy, The NHLBI / JHU Proteomics Retreat, Baltimore, MD (oral).
2014/10/10-14, The use of QABIT-ESI-HPLC-MS/MS for quantitation of tissue sialylation in a mouse model of GNE myopathy, 30^thAsilomar Conference on Mass Spectrometry: Advanced in glycomics and glycoproteomics, methods and applications, Pacific Grove, CA. (oral)
2014/9/8-10, Glycomic analysis of prostate cancer tissue and serum, 9^thEarly Detection Research Network (EDRN) Scientific Workshop, Bethesda, MD.
2014/06/15-19, Identification and quantitation of N-glycans in dyssynchronous heart failure, 62nd ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD.
2014/05/19, Glycan and protein analysis of mouse tissue using chemoenzymatic immobilization and mass spectrometry, NIH & FDA Glycosciences Research Day, Bethesda, MD. (oral)
2014/03/26-28, Quantitative analysis of N-glycosylation in dyssynchronous heart failure, Inter PEG 2014, Bethesda, MD. (oral)
2013/06/27, Glycomics analysis using solid-phase glycan extraction on chip and chipLC-MS, Glyco22, Dalian, China. (oral)
2012/9/9, Glycomics analysis using chemical immobilization of glycans, solid-phase glycan modifications, and tandem mass spectrometry, Boston, MA.
2012/5/1, Solid-phase glycan extraction for glycoprotein analysis, The NHLBI / JHU Proteomics Retreat, Baltimore, MD. (oral)
2012/4/26, Glycopeptide, glycosite, and glycan analysis by solid-phase extraction, Baltimore, MD.
2012/5/8, Glycan analysis by solid-phase capture and release using reversible reaction to hydrazide, 1^stAnnual Area-wide Glycobiology Poster Session, Baltimore, MD.
2012/3/27, Novel fabrication process for transverse and longitudinal mode PZT actuators, Proceedings of Mid-Atlantic Micro/Nano Alliance Spring Symposium, Annapolis, MD.
2012/2/25, Glycan analysis by reversible reaction to solid support and mass spectrometry, 7^thAnnual Johns Hopkins Prostate Research Day, Baltimore, MD.
2012/3/27, Traveling wave annular ultrasonic micromotors using bulk PZT, Microsystems for Measurement and Instrumentation (MAMNA), Annapolis, MD.
2012/3/27, Novel fabrication process for transverse and longitudinal mode PZT actuators, Microsystems for Measurement and Instrumentation (MAMNA), Annapolis, MD.
2011/11/10, Glycan analysis by solid-phase capture and release using reversible reaction to hydrazide, Seattle, WA.
2011/9/14, Hydrazide coated chip for capture and on target analysis of glycans, 7^thEDRN Scientific Workshop, Bethesda (highlight poster).
2011/6/9, Glycoproteomics identification and integration, presented to ADA Technologies, Inc., Denver, CO. (Oral)
2011/6/5, Hydrazide coated chip for capture and on target analysis of glycans, ASMS 2011, Denver, CO. (Oral)
2011/6/15, Hydrazide coated chip for glycan imaging,” NIH&FDA Glycoscience Research Day, Bethesda, MD.
2011/3/14, Lab-on-a-chip for glycoprotein analysis, Johns Hopkins University National Heart Lung Brain Institute (NHLBI) Proteomic Innovation Retreat on Heart Failure, Baltimore。
2009/6/21, Microfluidic two-dimensional IEF-CZE for proteomics, Transducers 2009, Denver, CO. (Oral)
2008/5/10, Protein two-dimensional separation on spatially-multiplexed polymer microchip platform, Proceedings of 32^ndInternationalSymposium on High Performance Liquid Phase Separations and Related Techniques(HPLC), Baltimore, MD
2008/10/12, Spatially-multiplexed protein separation enabled by multifunctional photopolymerized gels, MicroTAS 2008, San Diego, CA.
2006/11/5, Automated two-dimensional microfluidic protein profiling combining IEF and SDS gel electrophoresis, MicroTAS 2006, Tokyo, Japan. (Oral)
2005/9/26, Electrochemical migration of land grid array sockets under highly accelerated stress conditions, IEEE 51^stHolm Conference, Chicago, IL. (Oral)

教学

2007年秋季，“电子与仪器”课程助教
2013年夏季，在“糖生物学技术”课程中进行N糖分析的实验室教学
固相法N-聚糖分析讲座，使用GIG进行N-聚糖分析的动手实验，使用MALDI-MS / MS进行质谱分析，MS上的数据分析和报告
2015年夏季课程“糖生物学技术”中有关N-聚糖和O-聚糖分析的实验室教学
关于使用自动化进行N-聚糖分析的讲座，使用GIG Automation进行N-聚糖分析的动手实验
使用MALDI和ESI MS / MS进行质谱分析
2012-2015培训博士后，研究生和暑期实习生进行样品制备（糖组学和糖蛋白组学），质谱分析和数据分析

学术活动
2017/2018：NIH＆FDA糖科学研究日海报评审
2019年：NIH和FDA糖科学研究日会议主席（癌症）
2018年：ACS全国秋季会议，分析化学分会主席（糖生物学）
2016-2019年：CASMS委员会成员
2019-至今：CASMS执行委员会委员

社会学术兼职
2007年至今 IEEE设备和材料研究
2007年至今 IEEE高级封装
2010年至今 IEEE MEMS Journal
2010年至今 电化学学会杂志
2011年至今 蛋白质组研究杂志
2011年至今 电泳
2001年至今 分子生物系统
2011年至今 分离科学杂志
2011年至今 质谱快速通信
2011年至今 色谱杂志A
2012年至今 分析化学
2012年至今 临床蛋白质组学
2018年至今 血液与肿瘤学杂志
2018年至今 病理学杂志》
2018年至今 化学科学
2018年至今 ChemComm
2019年至今 Analytica Chimica Acta
2019年至今 基因组蛋白质组学与生物信息学

学术协会
2003-2011年 IEEE
2010年至今 美国质谱学会（ASMS）
2010年至今 美国化学会（ACS）
2011年至今 糖生物学学会（SfG）
2011年至今 世界人类蛋白质组组织（HUPO）和USHUPO
2015年至今 中美色谱学会（CACA）