姓　　名：仇晓琰
职称职务：特聘副教授
联系电话：
电子邮箱：xqiu@suda.edu.cn
办公地址：云轩楼1325
个人简介：
一、学习工作经历
1、学历背景：
1995.9－1999.6,北京大学，本科学士
1999.9－2001.6,RensselaerPolytechnicInstitute，硕士
2001.9－2007.5,耶鲁大学，博士
2、工作经历：
2007.7－2011.9,宾夕法尼亚大学，医学院生物物理与生化系，博士后
2011.9－2012.10,加州大学旧金山分校，药学院药物化学系，博士后
2013.1－ 苏州大学，药学院，副教授
二、研究方向
(1)多肽配体的设计和发现
(2)受体信号传导活性的调控
(3)靶向抗癌药物的研发
三、主要研究成果
以多肽结构和活性为研究对象先后在JACS和PNAS等杂志上发表十多篇研究论文。
代表性论文：
1. Li J., Qiu X.J. Quantification of Membrane Protein Self-Association with a High-Throughput Compatible Fluorescence Assay, Biochemistry 2017; 56(14): 1951-1954.
2. Li J., Qiu X. Studies of Conformational Change of The C-Terminal Amphipathic Helix of The Influenza A M2 Protein by FRET, Progress in Biochemistry and Biophysics 2016; 43(8): 796-800.
3. Lanci C.J., MacDermaid C.M., Kang S.G., Acharya R., Noth B., Yang X., Qiu X.J., Degrado W.F., Saven J.G. Computational design of a protein crystal, PNAS 2012; 109(19): 7304-7309.
4. Ghosh A., Qiu J., Degrado W.F., Hochstrasser R.M. Tidal surge in the M2 proton channel sensed by 2D IR spectroscopy, PNAS 2011; 108(15): 6115-6120.
5. Wang J., Qiu J.X., Soto C., Degrado W.F. Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus, Current Opinion in Structural Biology 2011; 21(1): 68-80. (Review)
6. Tang J., Yin H., Qiu J., Tucker M.J., DeGrado W.F., Gai F. Using two fluorescent probes to dissect the binding, insertion, and dimerization kinetics of a model membrane peptide, J. Am. Chem. Soc. 2009; 131(11): 3816-3817.
7. Goodman J.L., Petersson E.J., Daniels D.S., Qiu J.X., Schepartz A. Biophysical and structural characterization of a robust octameric beta-peptide bundle, J. Am. Chem. Soc. 2007; 129(47): 14746-14751.
8. Petersson E.J., Craig C.J., Daniels D.S., Qiu J.X., and Schepartz A. Biophysical characterization of a beta-peptide bundle: comparison to natural proteins, J. Am. Chem. Soc. 2007; 129(17): 5344-5345.
9. Daniels D.S., Petersson E.J., Qiu J.X., and Schepartz A. High resolution structure of a beta-peptide bundle, J. Am. Chem. Soc. 2007; 129(6): 1532-1533.
10. Qiu J.X., Petersson E.J., Matthews E.E., and Schepartz A. Toward beta-amino acid proteins: a cooperatively folded beta-peptide quaternary structure, J. Am. Chem. Soc. 2006; 128: 11338-11339.
11. Hart S.A., Bahadoor A.B.F., Matthews E.E., Qiu X.J., and Schepartz A. Helix macrodipole control of beta-peptide 14-Helix stability in water, J. Am. Chem. Soc. 2003; 125(14): 4022-4023.