个人信息
科学研究
成果奖励
教学招生








个人信息


个人简介
个人简介
B.S., Hunan Agricultural University, 1983
M.S., Sichuan Agricultural University, 1986
Ph.D., University of Edinburgh, United Kingdom, 1996
Postdoctoral Fellow, Medical College of Georgia, 1996 – 1998
Postdoctoral Associate, University of Ottawa, 1998 – 2001
Research Instructor, Vanderbilt University, 2002 – 2005
Assistant Professor, Cornell University, 2006-2014



研究领域
The Long Lab studies:(1) transcriptional control ofcell fate decisions of early pancreatic epithelial cellsduring mammalianembryonic development;(2) cellular and molecular mechanisms of hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC);and(3) genetic factors and signaling pathways mediatingcellularstress-induced neurodegeneration and celldeath in the central nervous system (CNS).Our long-term goalhas beentoidentifynoveltherapeutic intervention targetsand develop new strategies formoreeffectivepreventionand treatment ofchronic human diseases, including diabetesmellitus,neurodegenerativediseases, virallyand nonvirallyinducedliver cancers.

基本信息






龙乔明
职称：教授
院部/部门：剑桥-苏大基因组资源中心
学历：
学位：
毕业学校：
毕业专业：

联系方式


通讯地址：
邮政编码：
电子邮箱：qmlong@suda.edu.cn
联系电话：
传真号码：
办公地点：医学部





科学研究



科研团队





论文


SELECTED PUBLICATIONS:
1.Sha, H.B.,Sun, S.Y., Francisco, A.B.,Ehrhardt,N.,Xue, Z., Liu, L., Lawrence, P., Frits
Mattijssen, F.,Guber, R.,Panhwar, M.S.,Brenna, J.T., Hang Shi, H.,Xue, B.Z., Sander
Kersten, S.,Bensadoun,A.,*Péterfy, M.,*Long, Q.M. and*Qi, L. (2014) The ER-associated
Degradation Adaptor Protein Sel1L Regulates LPL Secretion and Lipid Metabolism.
Cell Metabolism；Sep 2; 20(3): 458-470. (*Co-senior author).
2.Sun, S. Shi, G., Han, X., Francisco, A.B.,Ji, Y.,Mendonca, N., Liu, X.,Locasale, J.W.,
Simpson, K.W., Duhamel, G.E.,Kersten, S., Yates, J.R. 3rd,*Long, Q.M. and*Qi, L. (2014)
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation,
endoplasmic reticulum homeostasis, and survival.ProcNatlAcadSciUSA. Jan 22. E582-
591.(*Co-corresponding author).
3.Qin, L.L,Xu, J., Wu, Z.F., Zhang, Z., Li, J.Q.,*Wang, C. and*Long, Q.M. Notch1-mediated
signaling regulates proliferation of porcine satellite cells (PSCs).2013;Cellular Signaling
25: 561–569.(*Co-corresponding author).
4.Francisco, A.B., Singh, R.,Sha, H., Yan, X., Qi, L., Lei, X.G. and *Long, Q.M.Haploid
insufficiency of Suppressor Enhancer Lin12 1 Like (SEL1L) protein predisposes mice to
high fat diet induced hyperglycemia.Journal of Biological Chemistry.2011; 286 (24):
21231-21238.(*Corresponding author).
5.Francisco, A.B., Singh, R., Li, S.,Vani, A., Yang, L., Munroe, R.J.,Diaferia, G.,Cardano, M.,
Biunno, I., Qi, L.,Schimenti, J.C. and *Long, Q.M. Deficiency of SuppressorEnahncerLin
12 1 Like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic
lethality.Journal of Biological Chemistry. 2010; 285 (18):13694-13703. (*Corresponding
author).
6.Li, S., Francisco, A.B., Han, C.,Pattabiraman, S., Foote, M.R., Giesy, S.L., Wang, C.,
Schimenti, J.C., Boisclair, Y.V. and *Long, Q.M.The full-lengthisoformofpleckstrin
homology domain-interacting protein (PHIP) regulates postnatal growth independently of
insulin-like growth factor 1.FEBSlett.2010; 584:4121-4127. (*Corresponding author).
7.Li, S., Francisco, A. B.,Munroe, R. J.,Schimenti, J. C.and*Long, Q.M.SEL1L deficiency
impairs growth and differentiation of pancreatic epithelial cells.BMCDevelopmental Biology.
2010; 10:19.(*Corresponding author).
8.Masui, T.,Long, Q.M.,Beres, T.M., Magnuson, M.A. and MacDonald, R.J.Earlypancreatic
development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1bHLHcomplex.
Genes & Development.2007; 21:2629-2643.
9.Long, Q.M., Huang, H.,Shafizadeh, E. and Lin, S.Stimulation oferythropoiesisby inhibiting
a new hematopoietic death receptor in transgeniczebrafish.Nature Cell Biology. 2000;
2:549-552.
10.Wang, H.,Long, Q.M., Scott, D.M.,Sassa, S. and Lin. S.Azebrafishmodel for
hepatoerythropoieticporphyria.Nature Genetics.1998; 20 (3): 239-43.
11.Long, Q.M.,Meng, A.M., Wang, H.,Jessen, R.J., Farrell, M. and Lin, S.GATA-1 expression
pattern can be recapitulated in living transgeniczebrafishusing GFP reporter
gene.Development. 1997; 124(20): 4105-4111.

荣誉奖励






开授课程


The Science ofBiology、实验动物学
招生信息