汤日宁
博士生导师 东南大学附属中大医院
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办公地点：中大医院2号楼9楼 电子邮箱：tangrn77@163.com
通讯地址：南京市丁家桥87号












研究方向


1. 慢性肾脏病矿物质和骨代谢异常（CKD-MBD）发病机制的研究
2. 糖尿病肾病发病机制的研究






荣誉奖励


汤日宁 博士，副主任医师、博士生导师、科主任助理。东南大学附属中大医院肾科规培生教学负责人，溧水人民医院肾科科主任。学会任职和荣誉：中华医学会肾脏病分会青年委员，中国医师协会整合医学肾脏病学分会委员，江苏省医学会肾脏病分会委员，中国非公立医疗机构协会肾脏病透析专业委员会青年分委会副主任。国家自然科学基金评审专家，教育部学位论文-学位中心评审专家。研究领域主要涉及慢性肾脏病心血管并发症，矿物质及骨代谢异常疾病。先后获得教育部自然科学一等奖、江苏省科技进步二等奖、南京市科技进步二等奖等政府成果奖励3项，获得江苏省卫生厅医学新技术引进奖一等奖1项。主持国家自然科学基金面上项目3项，江苏省自然科学基金1项，江苏省科教强卫医学重点人才，江苏省第三层次“333工程”培养对象，江苏省高层次人才“六个一工程”拔尖人才项目。获得江苏省优秀硕士学位论文、江苏省优秀博士学位论文和东南大学优秀博士学位论文各1项等。




学术成果



发表部分代表性论著如下：
1.Chen SJ, Lv LL, Liu BC, Tang RN（通讯作者）. Crosstalk between tubular epithelial cells and glomerular endothelialcells in diabetic kidney disease. CellProlif. 2020;00:e12763.
2.Ni LH, Song KY, Wang XC, Tang RN(通讯作者)et al. Efficacy and safety of cinacalcet and activevitamin D in the treatment of secondary hyperparathyroidism in patients withchronic kidney disease: A Network meta-analysis. Ann TranslMed. 2019;7(14):322.
3.Ni LH, Tang RN, Yuan C, Tang RN(通讯作者)et al. FK506 prevented bone loss instreptozotocin-induced diabetic rats via enhancing osteogenesis and inhibitingadipogenesis. Ann TranslMed. 2019;7(12):265.
4.Ni LH, Tang RN(通讯作者), Yuan C, Song KY, Wang LT, Zhang XL, Lv LL, Wang B, Wu M, Tang TT, Li ZL1, Yin D, Cao JY, Wang XC, Liu H, Chen Q, Liu BC.Cinacalcetattenuated bone loss via inhibiting parathyroid hormone-induced endothelial-to-adipocytetransition in chronic kidney disease rats. Ann TranslMed. 2019;7(14):312.
5.陈思洁, 刘必成, 汤日宁（通讯作者）. 慢性肾脏病骨脂肪细胞在骨质疏松进展中的作用[J]. 中华肾脏病杂志, 2019, 035(006):476-480.
6.Ni LH, TangRN(共同第一作者), Lv LL, Wu M, Wang B,Wang FM, Ni HF, Song KY, Wang LT, Meng-Zuo, Chen Q, Liu BC. A?rat?model?of?SHPT?with boneabnormalities in?CKD?induced by adenine and a high phosphorus?diet. BiochemBiophys Res Commun. 2018;498(3):654-659
7.王立婷,汤日宁（通讯作者）,刘必成.慢性肾脏病-矿物质和骨代谢异常动物模型建立方法. 中华医学杂志. 2018,98(10):798-800.
8. Tang RN，Wu P，An L，NADPH oxidase p22phoxC242T polymorphism is associated with macroalbuminuria in diabetic patients: Ameta-analysis. Journal of Diabetes and Its Complications，2017;31(7)：1207-1211
9.Zhu DD, Tang RN(共同第一作者), Lv LL, Wen Y, Liu H, Zhang XL, Ma KL, Liu BC.Interleukin-1β mediates high glucose inducedphenotypic transition in human aortic endothelial cells. Cardiovasc Diabetol. 2016;15:42.
10.Wu PP, Tang RN(共同第一作者), An L. A meta-analysis ofMTRR A66G polymorphism and colorectal cancer susceptibility. J BUON. 2015;20(3):918-922.
11.Wu M, Tang RN (共同第一作者), Liu H, Pan MM, Lv LL, Zhang JD, Crowley SD, LiuBC. Cinacalcet ameliorates cardiac fibrosis in uremic hearts through suppressionof endothelial-to-mesenchymal transition. Int J Cardiol, 2014; 171(3):e65-69.
12.Wu M, Tang RN (共同第一作者), Liu H. Ma KL. Lv LL. Liu BC. Nuclear translocationof β-Catenin mediates the parathyroid hormone-induced endothelial-to-mesenchymaltransition in human renal glomerular endothelial cells. J Cell Biochem, 2014; 115(10):1692-1701.
13.TangRN, Lv LL, Zhang JD, Dai HY,Li Q,Zheng M,Ni J,Ma KL,Liu BC.Effects of angiotensin II receptor blocker on myocardialendothelial-to-mesenchymal transition in diabetic rats. Int J Cardiol, 2013; 162(2):92-99.
14.Tang R, Gao M, Wu M, Liu H, Zhang X, Liu B. High glucosemediates endothelial-to-chondrocyte transition in humanaortic endothelial cells. Cardiovasc Diabetol, 2012, 11:113.
15.Tang RN, Li Q, Lv LL, Dai HY, Zheng M, Ma KL, Liu BC. Angiotensin II mediates thehigh-glucose-induced endothelial-to-mesenchymal transition in human aortic endothelialcells. Cardiovasc Diabetol 2010; 9:31.
16.Wu M, Tang RN, Liu H, Xu M, Pan MM, Liu BC. Cinacalcet attenuates the renal en0dothelial-to-mesenchymal transition in rats withadenine-induced renal failure. Am J Physiol Renal Physiol, 2014; 306(1):F138-146.
17.JiangH, Tang RN(共同第一作者), Wang J. Linezolid versus vancomycin orteicoplanin for nosocomial pneumonia: meta-analysis of randomised controlledtrials. Eur J Clin Microbiol Infect Dis. 2013;32(9):1121-1128.

参编书目：
1.刘必成，汤日宁，等。肾脏纤维化-基础与临床。北京，科学出版社。2016.1
2.汤日宁，王美美。慢性缺血性肾病的诊治进展。内科学诊治进展。北京，军事医学科学出版社，2008.12
3.汤日宁，刘必成。慢性缺血性肾病诊治进展。慢性肾脏病：新理论与实践。南京，东南大学出版社，2008.1