洪鑫
硕士生导师 东南大学附属中大医院
联系电话：** 办公时间：工作日
传 真： 主页网址：
办公地点：中大医院脊柱外科中心 电子邮箱：xinhong102400@163.com
通讯地址：南京市鼓楼区丁家桥87号












研究方向


致力于骨科（脊柱外科）的临床、科研、教学工作。在临床研究方面，通过对术后大样本患者的随访观察以及风险因素预测分析，对椎间盘退变性疾病的治疗（尤其是微创手术）提出了较有价值的参考意见。在椎间盘退变性疾病的病因学、分子生物学修复等基础研究方向，进行了较为深入的探索，目前相关的研究正在逐渐深入开展，以期取得更具有实用价值的研究结果，更好地实现临床转化。




荣誉奖励


2009年江苏省科技进步二等奖
2016年江苏省卫生厅资助项目
2016年国家自然科学基金面上项目
2016年东南大学附属中大医院敬业奖




学术成果


部分代表性文章：
1.HongX, Zhang C, Wang F, Wu XT (2018) Large Cytoplasmic Vacuoles within NotochordalNucleus Pulposus Cells: A Possible Regulator of Intracellular Pressure ThatShapes the Cytoskeleton and Controls Proliferation. Cells Tissues Organs:1-7.doi:10.1159/
2.HongX, Shi R, Wang YT, Liu L, Bao JP, Wu XT (2018) Lumbar disc herniation treatedby microendoscopic discectomy : Prognostic predictors of long-termpostoperative outcome. Orthopade. doi:10.1007/s00132-018-3624-6
3.HongXin; Liu Lei; Bao Jun-Ping; Shi Rui; Fan Yu-Dong; Wu Xiao-Tao*,Characterization and risk factors analysis for reoperation aftermicroendoscopic discectomy to treat lumbar disc herniation, Orthopedics, 2015,38(6): e490~6.
4.HongXin，WuXiao-tao*，ZhuangSu-yang，BaoJun-ping，ShiRui, New cage for posterior minimally invasive lumbar interbody fusion: a studyin vitro and in vivo. , Orthopaedic Surgery, 2014.2, 6(1): 47~53.
5.XinHong, Shu Yang, Yuntao Wang, Lei Zhu, Kun Wang, Xiaotao Wu: Long-termradiological changes and clinical effect after microendoscopic discectomy(MED): a cross-sectional study. Int J Clin Exp Med 2018;11(6):5729-5735.
6.XinHong, Christoph W Michalski, ALCAM is associated with chemiresistance and tumorcell adhesion in pancreatic cancer. Journal of surgical oncology2010;101:564-569
7.SunHH, Hong X, Liu B, Cui JQ, Zhou ZM, Xie XH, Wu XT (2018) Survival analysis ofpatients with spinal chordomas. Neurosurg Rev. doi:10.1007/s10143-018-0968-7（Co-first author）
8.WangK, Hong X, Zhou BY, Bao JP, Xie XH, Wang F, Wu XT (2015) Evaluation oftransforaminal endoscopic lumbar discectomy in the treatment of lumbar discherniation. Int Orthop 39 (8):1599-1604. doi:10.1007/s00264-015-2747-1（Co-first author）
9.Xie,Z. Y; Zhang, C; Chen, L; Zhang, C; Zhang, C; Cai, F; Wang, X. H; Shi, R;Sinkemani, A; Yu, H. M; Hong, X*; Wu, X. T*, Acid-Sensing Ion Channel 1aRegulates Fate of Rat Nucleus Pulposus Cells in Acid Stimulus ThroughEndoplasmic Reticulum Stress, Biores Open Access, 2018.2.16, 7(1): 2~9. (Correspondingauthor)
10.ChenL, Liu L, Xie ZY, Wang F, Sinkemani A, Zhang C, Wang XH, Wang K, Hong X, Wu XT(2018) Endoplasmic Reticulum Stress Facilitates the Survival and Proliferationof Nucleus Pulposus Cells in TNF-alpha Stimulus by Activating Unfolded ProteinResponse. DNA Cell Biol 37 (4):347-358. doi:10.1089/dna.2017.4029 (Correspondingauthor)
11.XieZY, Chen L, Wang F, Liu L, Zhang C, Wang K, Cai F, Sinkemanni A, Hong X, Wu XT(2017) Endoplasmic Reticulum Stress Is Involved in Nucleus PulposusDegeneration and Attenuates Low pH-Induced Apoptosis of Rat Nucleus PulposusCells. DNA Cell Biol 36 (8):627-637. doi:10.1089/dna.2017.3736 (Correspondingauthor)