沈艳飞
博士生导师 东南大学医学院
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传 真： 主页网址：http://www.yshen.group/
办公地点：东南大学丁家桥校区 电子邮箱：Yanfei.Shen@seu.edu.cn
通讯地址：南京市鼓楼区丁家桥87号












研究方向


1.碳材料的设计、制备和功能化
2.生物界面电化学、（光）电化学与生物传感
3.疾病早期诊断、靶向给药





荣誉奖励


2014年 江苏省“六大人才高峰”第十一批高层次人才；
2014年 东南大学优秀青年教师
2017年江苏省优秀青年基金获得者





学术成果


发表包括J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Sci.、Anal. Chem.等SCI期刊论文100余篇，所发表的论文被SCI期刊论文引用3000余次，H-index 32，获授权专利4项。作为项目负责人承担国家自然科学基金、江苏省优秀青年基金等相关基金项目5项。


学术论文代表作如下：

2020
1. Deng Pan,# Zhengzou Fang,# Erli Yang,# Zhenqiang Ning, Qing Zhou, Kaiyang Chen, Yongjun Zheng, Yuanjian Zhang, and , Yanfei Shen*, Facile Preparation of WO3-x Dots with Remarkably Low Toxicity and Uncompromised Activity as Coreactants for Clinic Electrochemiluminescent Diagnosis. Angew. Chem. Int. Ed., 2020, DOI:10.1002/anie..[abs] (IF: 12.959)
2. Mengyuan Chen, Zhenqiang Ning, Kaiyang Chen, Yuanjian Zhang*, Yanfei Shen*, Recent Advances of Electrochemiluminescent System in Bioassay, Journal of Analysis and Testing， 2020, 4, 57–75.[abs]（see also in 专刊论文推荐：电化学发光体系在生物分析中的最新进展）
3.Zhenqiang Ning, Yongjun Zheng, Deng Pan,Yuanjian Zhang and Yanfei Shen*, Coupling aptazyme and catalytic hairpin assembly for cascaded dual signal amplified electrochemiluminescence biosensing. Biosens. Bioelectron., 2020, 150, 111945. abs (IF: 10.257)
4.Qing Zhou, Guanghui Li, Kaiyang Chen, Hong Yang, Mengran Yang, Yuye Zhang, Yakun Wan*, Yanfei Shen*, and Yuanjian Zhang*, Simultaneous Unlocking Optoelectronic and Interfacial Properties of C60 for Ultrasensitive Immunosensing by Coupling to Metal?Organic Framework, Anal.Chem., 2020, 92, 983-990. abs (IF: 6.785)
5. Khishigjargal Ganbat, Deng Pan, Kaiyang Chen, Zhenqiang Ning, Le Xing, Yuanjian Zhang, Yanfei Shen*, One-pot electrografting preparation of bifunctionalized carbon nanotubes for sensitive electrochemical immunosensing, J.Electroanal.Chem., 2020, 863, 113906.Abs (IF: 3.807)
6. Kaiyang Chen#, Jiyang Xue#，Qing Zhou, Yue Zhang, Mingming Zhang, Yuanjian Zhang, Hai Zhang* and Yanfei Shen*, Coupling Metal-Organic Framework Nanosphere and Nanobody for Boosted Photoelectrochemical Immunoassay of Human Epididymis Protein 4, Anal. Chim. Acta, 2020, 1107, 145-154. abs (IF: 5.977)
2019
1.Deng Pan, Kaiyang Chen, Qing Zhou, Jinjin Zhao, Huaijia Xue, Yuanjian Zhang and Yanfei Shen*, Engineering of CdTe/SiO2 nanocomposites: Enhanced signal amplification and biocompatibility for electrochemiluminescent immunoassay of alphafetoprotein. Biosens.Bioelectron.2019, 131, 178-184. abs (IF: 10.257)
2.Huaijia Xue, Jinjin Zhao, Qing Zhou, Deng Pan, Yue Zhang, Yuanjian Zhang and Yanfei Shen*, Boosting the Sensitivity of a Photoelectrochemical Immunoassay by Using SiO2@polydopamine Core?Shell Nanoparticles as a Highly Efficient Quencher. ACS Appl.Nano Mater.2019, 2, 1579-1588. abs
3.Huaijia Xue, Kaiyang Chen, Qing Zhou, Deng Pan, Yuanjian Zhang and Yanfei Shen, Antimony selenide/graphene oxide composite for sensitive photoelectrochemical detection of DNA methyltransferase activity, J. Mater. Chem. B.2019, 7*, 6789-6795. abs (IF: 5.344)
4. Yongjun Zheng, Deng Pan, Yue Zhang, Yuanjian Zhang, Yanfei Shen*, Hemicyanine-based near-infrared fluorescent probe for the ultrasensitive detection of hNQO1 activity and discrimination of human cancer cells. Anal. Chim. Acta, 2019, 1090, 125-132. abs (IF: 5.977)


2018

1. Qing Zhou, Huaijia Xue, Yuye Zhang, Yanqin Lv, Hongguang Li, Songqin Liu, Yanfei Shen*, and Yuanjian Zhang*, Metal-Free All-Carbon Nanohybrid for Ultrasensitive Photoelectrochemical Immunosensing of alpha-Fetoprotein. ACS Sens. 2018, 3, 1385-1391. abs（IF：7.333）
2. Huizhen Hu, Deng Pan, Huaijia Xue, Mingming Zhang, Yuanjian Zhang and Yanfei Shen*, A photoelectrochemical immunoassay for tumor necrosis factor-α using a GOPTCNH2 nanohybrid as a probe. J.Electroanal.Chem. 2018, 824, 195-200. abs (IF:3.807)
3.Deng Pan, Guanghui Li,Huizhen Hu, Huaijia Xue, Mingming Zhang, Min Zhu, Xue Gong, Yuanjian Zhang, Yakun Wan* and Yanfei Shen*, Direct Immunoassay for Facile and Sensitive Detection of Small Molecule Aflatoxin B1 based on Nanobody. Chem. Eur. J 2018, 24, 9869-9876. abs (IF：4.857)
4.Mingming Zhang, Guanghui Li, Qing Zhou, Deng Pan, Min Zhu, Runyu Xiao, Yuanjian Zhang, Guoqiu Wu,* Yakun Wan* and Yanfei Shen*, Boosted Electrochemical Immunosensing of Genetically Modified Crop Markers Using Nanobody and Mesoporous Carbon. ACS Sens. 2018, 3, 684. abs (IF：7.333)
5. Jinjin Zhao, Ning Pan, Fang Huang, Mohanad Aldarouish, Zhifa Wen, Rong Gao, Yuye Zhang, Hong-Ming Hu, Yanfei Shen,* and Li-xin Wang*, Vx3-Functionalized Alumina Nanoparticles Assisted Enrichment of Ubiquitinated Proteins from Cancer Cells for Enhanced Cancer Immunotherapy. Bioconjugate Chem. 2018, 29, 786. abs (IF：4.031)
6. Yue Zhang, Deng Pan, Qing Zhou, Jinjin Zhao, Ning Pan, Yuanjian Zhang, Li-xin Wang\* and Yanfei Shen\*，An enzyme cascade-based electrochemical immunoassay using a polydopamine-carbon nanotube nanocomposite for signal amplification. *J.Mater.Chem.B 2018,6,8180. abs (IF：5.344)

2017
1. Yanfei Shen*, Cheng Zhang, Chunguang Yan, Huiqin Chen and Yuanjian Zhang, Fabrication of porous graphitic carbon nitride-titanium dioxide heterojunctions with enhanced photo-energy conversion activity. Chin.Chem.Lett. 2017, 28, 1312.abs (IF:4.632)


2016
1. Qing Zhou,Guanghui Li, Yuanjian Zhang, Min Zhu, Yakun Wan* and Yanfei Shen*, A Highly Selective and Sensitive Electrochemical Immunoassay of Cry1C UsingNanobody and pi-pi Stacked Graphene Oxide/Thionine Assembly. Anal.Chem. 2016, 88, 9830?9836. abs (1区，Nature Index收录)
2. Jusheng Lu,Yanfei Shen* and Songqin Liu*,Enhanced light-driven catalytic performance of cytochrome P450 confined in macroporous silica. Chem.Commun.2016, 52, 7703.(IF:6.567)abs (1区，Nature Index收录)
3.Guanghui Li,Min Zhu,Lu Ma,Junrong Yan,Xiaoling Lu,Yanfei Shen* and Yakun Wan*, Generation of Small Single Domain Nanobody Binders for Sensitive Detection of Testosterone by Electrochemical Impedance Spectroscopy. ACS Appl.Mater.Interfaces 2016, 8, 13830-13839.abs（1区）


2015
1. Min Zhu, Min Li, Guanghui Li, Zikai Zhou, Hong Liu, Hongtao Lei, Yanfei Shen*, Yakun Wan*, Nanobody-based immunoassay for Bacillus thurineiensis Cry1Ab toxin by detecting the enzymatic formation of polyaniline. Microchim. Acta 2015, 182, 2451–2459. （IF：4.831）abs
2. Yanfei Shen*, Akinori Saeki , ShuSeki , Jeong-O Lee , Junko Aimi , and Takashi Nakanishi*，Exfoliation of Graphene and Assembly Formation with Alkylated-C60: A Nanocarbon Hybrid towards Photo-Energy Conversion Electrode Devices, Adv.Optical Mater. 2015, 3, 925–930.(IF: 5.188)abs


Before
1. Yanfei Shen and Takashi Nakanishi* Fullerene assemblies towardphoto-energy conversions. Phys. Chem. Chem. Phys., 2014, 16, 7199.abs
2.Yanfei Shen,* Juan Sebastian Reparaz, Markus Raphael Wagner, Axel Hoffmann, Christian Thomsen, Jeong-O Lee, Sebastian Heeg, Benjamin Hatting, Stephanie Reich, Akinori Saeki, Shu Seki, Kaname Yoshida, Sukumaran Santhosh Babu, Helmuth M?hwald and Takashi Nakanishi* Assembly of carbon nanotubes and alkylated fullerenes: nanocarbon hybrid towards photovoltaic applications. Chem. Sci., 2011, 2, 2243-2250.abs
3. Yanfei Shen, Andre G. Skirtach, Tomohiro Seki, Shiki Yagai, Hongguang Li, Helmuth M?hwald and Takashi Nakanishi* Assembly of Fullerene-Carbon Nanotubes: Temperature Indicator for Photothermal Conversion. J. Am. Chem. Soc., 2010, 132, 8566-8568.abs
4. Markus Antonietti, Yanfei Shen, Takashi Nakanishi, Michael Manuelian, Robert Campbell, Liang Gwee, Yossef A. Elabd, Nikhil Tambe, Rene Crombez, and John Texter* Single-Wall Carbon Nanotube Latexes. ACS Appl.Mater.Interfaces, 2010, 2, 649-653. abs
5.Takashi Nakanishi*, Yanfei Shen, Jiaobing Wang, Hongguang Li, Paulo Fernandes, Kaname Yoshida, Shiki Yagai, Masayuki Takeuchi, Katsuhiko Ariga, Dirk G. Kurth, Helmuth Moehwald. Superstructures and Superhydrophobic Property in Hierarchical Organized Architectures of Fullerenes Bearing Long Alkyl Tails J.Mater.Chem., 2010, 20, 1253 - 1260 (Dedicated Issue to Emerging Investigators in Materials Chemistry, Back Cover Picture) abs
6.Jiaobing Wang, Yanfei Shen, Stefanie Kessel, Paulo Fernandes, Kaname Yoshida, Shiki Yagai, Dirk G. Kurth, Helmuth Moehwald and Takashi Nakanishi* Self-Assembly Made Durable: Water-Repellent Materials Formed by Cros-Linking Fullerene Derivatives, Angew.Chem.Int.Ed. 2009, 48, 2166-2170.abs
7.Yanfei Shen, Jiaobing Wang, Uwe Kuhlmann, Peter Hildebrandt, Katsuhiko Ariga, Helmuth M?hwald, Dirk G. Kurth and Takashi Nakanishi* Supramolecular Templates for Nanoflake-Metal Surfaces, Chem.Eur.J, 2009, 15, 2763-2767.abs
8.Yanfei Shen, Yuanjian Zhang, Dongxue Han, Zhijuan Wang, Li Niu* and Ari Ivaska
Preparation of Colorless Ionic Liquids “on Water” for Spectroscopy, Talanta 2009, 78, 805-808. abs
9.Yanfei Shen, Yuanjian Zhang, Daniel Kuehner, Guifu Yang, Fuyu Yuan and Li Niu* Ion-Responsive Behavior of Ionic-Liquid Surfactant Aggregates with Application to Controlled Release and Emulsification, ChemPhysChem, 2008, 9, 2198 – 2202. abs
9.Takashi Nakanishi,* Yanfei Shen, Jiaobing Wang, Shiki Yagai, Masahiro Funahashi, Takashi Kato, Paulo Fernandes, Helmuth M?hwald, and Dirk G. Kurth. Electron Transport and Electrochemistry of Mesomorphic Fullerenes with Long-Range Ordered Lamellae, J. Am. Chem. Soc., 130 (29), 9236–9237, 2008. abs
10. Yuanjian Zhang, Yanfei Shen, Daniel Kuehner, Shuixing Wu, Zhongmin Su, Shen Ye and Li Niu* Directing Single-Walled Carbon Nanotubes to Self-Assemble at Water/Oil Interface and Facilitate Electron Transfer, Chem. Commun. 2008, 4273-4275 . abs
11. Yuanjian Zhang, Yanfei Shen, Dongxue Han, Zhijuan Wang, Jixia Song, Fei Li, Li Niu* Carbon nanotubes and glucose oxidase bionanocomposite bridged by ionic liquid-like unit: Preparation and electrochemical properties. Biosensors and Bioelectronics 2007, 23(3) pp 438-443. [Abstract]
12. Yanfei Shen, Yuanjian Zhang, Xuepeng Qiu, Haiquan Guo, Li Niu* and Ari Ivaska Polyelectrolyte-functionalized ionic liquid for electrochemistry in supporting electrolyte-free aqueous solutions and application in amperometric flow injection analysis. Green Chem. 2007, 9, 746-753. [Abstract]
13.Yanfei Shen, Yuanjian Zhang, Qixian Zhang, Li Niu*, Tianyan You, and Ari Ivaska Immobilization of ionic liquid with polyelectrolyte as carrier. Chem.Commun. 2005, 4193-4195. [Abstract]
14. Jinghong Li*, Yanfei Shen, Yuanjian Zhang and Yang Liu “Room-temperature ionic liquids as medium to enhance the electrochemical stability of self-assembled monolayers of alkanethiol on gold electrode.” Chem. Commun. 2005, 360-362. [Abstract]
15. Yanfei Shen, Tian Wu, Yuanjian Zhang and Jinghong Li* “Comparison of two-typed (3-mercaptopropyl)trimethoxysilane-based networks on Au substrates” Talanta 2005, 65, 481-488. [Abstract]
16. Yanfei Shen, Shaoyun Gong, Weihong Zhou, Jinghong Li* “Self-assembled monolayers of 1-(2-CyanoethyI) pyrrole on gold electrode” Colloids and Surfaces A 2005, 257-258, 149-154. [Abstract]
17.Yuanjian Zhang, Yanfei Shen, Junhua Yuan, Dongxue Han, Zhijuan Wang, Qixian Zhang and Li Niu* “Design and Synthesis of Multifunctional Materials Based on Ionic Liquid Backbone” Angew. Chem. Int. Ed. 2006, 45, 5867-5870. [Abstract]
18. Yuanjian Zhang, Yanfei Shen, Dongxue Han, Zhijuan Wang, Jixia Song and Li Niu* “Reinforcement of Silica with Single-Walled Carbon Nanotubes through Covalent Functionalization” J. Mater. Chem. 2006, 16, 4592-4597. [Abstract]
19. Yuanjian Zhang, Yanfei Shen, Jinghong Li, Li Niu*, Shaojun Dong, and Ari Ivaska “Electrochemical functionalization of single-walled carbon nanotubes in large quantities at a room-temperature ionic liquid supported three-dimensional network electrode” Langmuir 2005, 21, 4797-4800. [Abstract]
20. Yuanjian Zhang, Jun Li, Yanfei Shen, Meijia Wang, Jinghong Li*, “Poly-L-lysine functionalization of single-walled carbon nanotubes”. Journal of Physical Chemistry B 2004, 108, 15343-15346. [Abstract]