陈峻青
副教授 化学化工学院
联系电话： 办公时间：周一—周五全天
传 真： 主页网址：
办公地点：东南大学化学化工学院 电子邮箱：jqchen@seu.edu.cn
通讯地址：南京市江宁区东南大学化学化工学院












研究方向


生物催化，生物制药




荣誉奖励


1 2015年江苏省“六大人才高峰”第十二批高层次人才选拔培养资助（生物技术和新医药产业）
2 2015年度宿迁市“创业创新领军人才集聚计划”（创新人才）
3 2014江苏省科学技术奖，二等奖（排名第二）
4 2013 江苏省百件优质发明专利，一种酮还原酶基因及其应用 排名第一




学术成果



发表论文


1.JunqingChen, MinSun, JinCai, MengCao, WenZhou, MinJi. The Synthesis and CrystalStructure of (4a,8b,13b,16b)-13-Methyl-16,18-diol-17-Norkaurane: A SimultaneousReduction Product of Isosteviol. J Chem Crystallogr. 2011, 41:519–522
2.JunqingChen, Xiaoming Zha, MinSun, JinCai, WenZhou, MinJi. Synthesis and In VivoAcute Antihyperglycemic Evaluation of Novel Isosteviol Derivatives. Letters inDrug Design & Discovery. 2010, 7, 686-693
3.Zhou GX; Li LS; Xing J; Cai J; Chen JQ; Liu PD; Gu N ; Ji M.Layer-by-layer construction of lipid bilayer on mesoporous silica nanoparticleto improve its water suspensibility and hemocompatibility. Journal of sol-gelscience and technology. 2017, 82(2):490-499
4.Zhilong Zhang, Gaoxin Zhou,Bo Chen, Jin Cai,Junqing Chen.Xuan Wu, Wenxiou Qi, Min Ji. Novel yolk–shell structured silicananosphere with a movable silica-coated gold core. Journal of Sol-Gel Scienceand Technology. 2016, 77(2): 516-520
5.Zhou GX; Li LS; Xing J; Jalde S; Li Y; CaiJ; Chen JQ; Liu PD; Gu N; Ji M. Redox responsive liposomal nanohybrid cerasomes for intracellular drug delivery. Colloidsand Surfaces B-Biointerfaces. 2016,148: 518-525
6. Liu HD; Chen B; Cai J; Chen JQ; Ji M. The trifluoromethylationof iminium salts by the addition of trifluoromethyltrimethylsilane. Journal ofChemical Research. 2016, 6: 379-381
7.Xi Zong, Jin Cai, Junqing Chen, Peng Wang, Gaoxin Zhou, Bo Chen, Wei Li,Min Ji. Design and synthesis of imidazole N–Hsubstituted amide prodrugs as inhibitors of hepatitis C virus replication. Bioorganic& Medicinal Chemistry Letters. 2015, 25(16): 3147-3150
8. Liu HD; Lv YF ; Li Y; Cai J; Chen JQ; Qin, Y; Ji, M. A novel andefficient synthesis of anti-cancer agent, mereletinib. Journal of ChemicalResearch. 2015, 39(6): 318-320
9.Cai J; Wei HT; Hong KH; Wu XQ; Zong X; CaoM; Wang P; Li LS; Sun CL; Chen B; Zhou GX; ChenJQ; Ji M. Discovery, bioactivity and docking simulation of Vorinostatanalogues containing 1,2,4-oxadiazole moiety as potent histone deacetylaseinhibitors and antitumor agents. Bioorganic & Medicinal Chemistry. 2015,23(13): 3457-3471
10.Wang P; Cai J; Chen JQ; Ji, M. Agarose-Alumina Composite Supported PalladiumCatalyst for Suzuki Coupling Reactions. Journal of The Brazilian ChemicalSociety. 2015, 26(4): 748-754
11.Chunlong Sun, Yang Wu,Peng Wang, Gaoxin Zhou, Xi Zong, Bo Chen, Jin Cai, Junqing Chen, Min Ji. A novelnear-infrared fluorescent probe was synthesized and its application in imagingof living cells. Journal of Sol-Gel Science and Technology. 2014, 71(2):211–216
12.Peng Wang, Jin Cai,Junqing Chen, MinJi. A novel near-infraredfluorescent probe was synthesized and its application in imaging of livingcells. European Journal of Medicinal Chemistry. 2015, 93: 1-8
13.Chunlong Sun, Jin Cai, Junqing Chen, Yang Wu,Peng Wang, Gaoxin Zhou, Xi Zong, Bo Chen, Yongfeng Lv,Min Ji. The Synthesis of a Novel Near-Infrared Fluorescent Probe and itsApplication in Imaging of Living Cells. Applied Biochemistry and Biotechnology.2015, 175(3): 1644–1650



已授权专利
1 陈峻青，石利平，尹晓龙，王清 一种酮还原酶基因及其应用，CNB
2 陈峻青，李黎，吉民，戚文秀 一种链格孢菌Y1309?1及其应用，CNB
3 陈峻青，吉民，戚文秀 一种链格孢菌Y1309-1在制备纳米金方面的应用，CNB
4 石利平，蔡进，陈峻青，吉民，龚仕荣，万新强，徐春涛 一种索非布韦中间体及其制备方法，CNB
5 吉民，胡兵，蔡进，曹萌，张入仁，王鹏，常维维，陈峻青，宗玺 Hedgehog信号通路抑制剂，CNB
6 蔡进，吉民，曹萌，陈峻青 基于MIM蛋白环肽抑制剂的靶向长循环脂质体及其制备方法与应用，CNB
7 陈峻青，石利平，尹晓龙，王清 一种酮还原酶基因及其应用，CNB
8 陈峻青，蔡进，吉民，尹晓龙，漆志文，石利平，徐春涛 一种卤醇脱卤酶基因突变体及其应用，CNB
9 吉民，陈峻青，余佳，周文 异甜菊醇衍生物及其应用，CNB


科研项目

1.国家自然科学基金面上项目，**，用于生物标记及荧光成像dendrimer分子的多光子上转换荧光发射及荧光共振能量传递、2012/1/1-2015/12/30，60万元，已结题，参与。
2.国家自然科学基金面上项目，**，多巴胺D3受体配体用于治疗帕金森综合症等中枢疾病、2005/1/1- 2007/12/31，21万元，已结题，参与。
3.参与或主持江苏省产学研前瞻项目、江苏省支撑计划(社会发展)、江苏省重大成果转化项目、江苏省基础研究计划项目及多项企业合作项目。