姓名： 胡晓玉 性别： 女 职务： 职称： 教授 导师类别：博士生导师 办公室：1 号楼 902研究领域：有机功能材料、纳米药物载体、超分子自组装、超分子聚合物材料 电话： 18761895025 Email: huxy@nuaa.edu.cn 课题组网站：https://www.x-mol.com/groups/Hu_Xiao-Yu 个人简介： 胡晓玉教授 2011 年 6 月毕业于中科院成都生物所，获药物化学理学博士学位；2011 年 7 月—2013 年 6 月，南京大学博士后，2013 年 7 月评为副研究员；2016 年 6 月－2018 年 6月，德国杜伊斯堡-埃森大学，洪堡学者（Humboldt Fellowship for Experienced Researcher）； 2018 年 7 月起聘为南京航空航天大学教授，研究方向为有机超分子材料化学，主要涉及超分子组装，功能材料及纳米药物载体方面的研究。研究工作以分子设计合成为基础，以分子识别与超分子可控组装为手段，以有机功能材料构筑为导 向，旨在实现系列新型“智能”有机超分子组装体系的可控构筑及其功能化。 近年主持国家自然科学基金面上项目、青年项目，江苏省优青项目、青年基金项目，南京市留学人员科技创新项目（A 类）等。先后在包括 Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Acc. Chem. Res., Chem. Mater., Small 等国际高影响力刊物上发表 SCI 论文 70余篇。研究成果目前已被 SCI 引用 3500 余次。2018 年获得江苏省教育教学与研究成果奖（三等奖，3/5），以及江苏省科学技术奖一等奖（7/10）。担任江苏省化学化工学会大环与超分子专业委员会青年委员；并受邀担任“Chinese Chemical Letters”、“Frontiers in Chemistry”、 “RSC Advance”及“Green Synthesis & Catalysis”期刊编委。 学术成果： 代表性文章 1). K. Wang, J. H. Jordan, X.-Y. Hu,* L. Wang. Supramolecular strategies for controlling reactivity within confined nanospaces. Angew. Chem. Int. Ed., 2020, 59, 10.1002/anie.202000045. (IF=12.959) 2). G. Sun, W. Qian, J. Jiao, T. Han, Y. Shi, X.-Y. Hu,* L. Wang.* Highly efficient artificial light-harvesting system with two-step sequential energy transfer based on supramolecular self-assembly. J. Mater. Chem. A, 2020, 8, 9590-9596. (IF=11.301) 3). W. Qian, M. Zuo, G. Sun, Y. Chen, T. Han, X.-Y. Hu,* R. Wang, L. Wang.* The construction of an AIE-based controllable singlet oxygen generation system directed by a supramolecular strategy. Chem. Commun., 2020, 56, 7301-7304. (IF=5.996) 4). X.-Y. Hu,* K. Wang,* J. H. Jordan, C. Su, L. Wang. General Strategies in Modulating Reactivity within Well-Defined Supramolecular Nanospaces, Supramolecular Catalysts, Leyong Wang and Chengyong Su, World Scientific Publishing, pp 1-27, Singapore, 2020. 5). M. Hao, G. Sun, M. Zuo, Z. Xu, Y. Chen, X.-Y. Hu,* L. Wang.* A supramolecular artificial light-harvesting system with two-step sequential energy transfer for photochemical catalysis. Angew. Chem. Int. Ed., 2020, 59, 10095-10100. (IF=12.959) 6). S. Wang, W. Gao, X.-Y. Hu,* Y.-Z. Shen, L. Wang. Supramolecular strategy for smart windows. Chem. Commun., 2019, 55, 4137-4149. (IF=5.996) 7). G. Sun, Z. He, M. Hao, Z. Xu, M. Zuo, X.-Y. Hu,* J.-J Zhu,* L. Wang.* Dual acid-responsive bola-type supramolecular vesicles for efficient intracellular anticancer drug delivery. J. Mater. Chem. B, 2019, 7, 3944-3949. (IF=5.344) 8). S. Wang, Z. Xu, T. Wang, T. Xiao, X.-Y. Hu(*), Y.-Z. Shen(*), L. Wang(*). Warm/cool-tone switchable thermochromic material for smart windows by orthogonally integrating properties of pillar[6]arene and ferrocene. Nat. Commun., 2018, 9, 1737. (IF=12.121) 9). S. Guo, Y. Song, Y. He, X.-Y. Hu(*), L. Wang(*). Highly efficient artificial light-harvesting systems constructed in aqueous solution based on supramolecular self-assembly, Angew. Chem. Int. Ed., 2018, 57, 3163-3167. (IF=12.959) 10). X.-Y. Hu(*), L. Gao, S. Mosel, M. Ehlers, E. Zellermann, H. Jiang, S. K. Knauer, L. Wang, C. Schmuck.* From supramolecular vesicles to micelles: Controllable construction of tumor-targeting nanocarriers based on host–guest interaction between a pillar[5]arene-based prodrug and a RGD-sulfonate guest. Small, 2018, 14, 1803952. (IF=11.459) 11). M. Zuo, W. Qian, Z. Xu, W. Shao, X.-Y. Hu(*), D. Zhang(*), J. Jiang(*), X. Sun, and L. Wang(*). Multi-responsive supramolecular theranostic nanoplatform based on pillararene and diphenylboronic acid derivatives for integrated glucose sensing and insulin delivery, Small, 2018, 14, 1801942.(IF=11.459) 12). M. Zuo, W. Qian, T. Li, X.-Y. Hu,* J. Jiang,* L. Wang.* Full-color tunable fluorescent and chemiluminescent supramolecular nanoparticles for anti-counterfeiting inks, ACS Appl. Mater. Interfaces, 2018, 10, 39214-39221. (IF=8.758) 13). W. Shao, X. Liu, G. Sun, X.-Y. Hu,(*) J.-J Zhu, L. Wang. Construction of drug-drug conjugate supramolecular nanocarriers based on water-soluble pillar[6]arene for combination chemotherapy. Chem. Commun., 2018, 54, 9462-9465. (IF=5.996). 14). Z. Xu, S. Wang, X.-Y. Hu,(*) J. Jiang,(*) X. Sun, L. Wang.(*) Sunlight-induced photo-thermochromic supramolecular nanocomposite hydrogel film for energy-saving smart window. Solar RRL, 2018, 1800204. (IF=7.527) 15). X.-Y. Hu(*), M. Ehlers, T. Wang, E. Zellermann, S. Mosel, H. Jiang, J.-E. Ostwaldt, S. K. Knauer, L. Wang, C. Schmuck.* Formation of twisted β-sheet tapes from a self-complementary peptide based on novel pillararene-GCP host-guest interaction with gene transfection properties. Chem.―Eur. J., 2018, 24, 9754-9759. (IF=4.857) 16). X. Liu, K. Jia, Y. Wang, W. Shao, C. Yao, L. Peng, D. Zhang(*), X.-Y. Hu(*), L. Wang. Dual-responsive bola-type supra-amphiphile constructed from water-soluble pillar[5]arene and naphthalimide-containing amphiphile for intracellular drug delivery. ACS Appl. Mater. Interfaces, 2017, 9. 4843-4850. (IF=8.758) 17). X. Liu, W. Shao, Y. Zheng, C. Yao, L. Peng, D. Zhang, X.-Y. Hu(*), L. Wang. GSH-Responsive supramolecular nanoparticles constructed by β-D-galactose-modified pillar[5]arene and camptotecin prodrug for targeted anticancer drug delivery. Chem. Commun., 2017, 53, 8596-8599. (IF=5.996) 18). L. Gao, T. Wang, K. Jia, X. Wu, C. Yao, W. Shao, D. Zhang, X.-Y. Hu(*), L. Wang(*). Glucose-responsive supramolecular vesicles based on water-soluble pillar[5]arene and pyridylboronic acid derivative for controlled insulin delivery. Chem.―Eur. J., 2017, 23, 6605-6614. (IF=4.857) 19). X.-Y. Hu, X. Liu, S. Qin, W. Zhang, C. Yao, Y. Li, D. Cao, L. M. Peng, L. Wang(*). Controllable construction of biocompatible supramolecular micelles and vesicles by water-soluble phosphate pillar[5,6]arenes for selective anti-cancer drug delivery, Chem. Mater., 2016, 28, 3778-3788. (IF=9.567) 20). S. Guo, X. Liu, C. Yao, C. Lu, X.-Y. Hu(*), L. Wang(*). Photolysis of a bola-type supra-amphiphile promoted by water-soluble pillar[5]arene-induced assembly, Chem. Commun., 2016, 52, 10751-10754. (IF=5.996) 21). X. Wu, L. Gao, X.-Y. Hu(*) L. Wang. Supramolecular drug delivery systems based on water-soluble pillar[n]arenes, Chem. Rec., 2016, 16, 1216-1227. (IF=6.163) 22). Y. Cao, Y. Li, X.-Y. Hu(*), X. Zou, S. Xiong, C. Lin, L. Wang(*). Supramolecular nanoparticles constructed by DOX-based prodrug with water-soluble pillar[6]arene for self-catalyzed rapid drug release, Chem. Mater., 2015, 27, 1010-1019. (IF=9.567) 23). X.-Y. Hu, Y. Cao, Y. Li, K. Jia, S. Qin, F. Zhou, C. Lin, D. Zhang, L. Wang(*). Dual photo- and pH-responsive supramolecular nanocarriers based on water-soluble pillar[6]arene and different azobenzene derivatives for intracellular anticancer drug delivery, Chem. Eur. J., 2015, 21, 1208-1220. (IF=4.857) 24). X.-Y. Hu, T. Xiao, C. Lin, F. Huang, L. Wang(*). Dynamic supramolecular complexes constructed by orthogonal self-assembly, Acc. Chem. Res., 2014, 47, 2041-2051. (IF=20.832) 25). Y. Cao(#), X.-Y. Hu(#), Y. Li, X. Zou, S. Xiong, C. Lin, Y.-Z. Shen, L. Wang(*). Multistimuli-responsive supramolecular vesicles based on water-soluble pillar[6]arene and SAINT complexation for controllable drug release, J. Am. Chem. Soc., 2014, 136, 10762-10769 (共同一作). (IF=14.612) 承担项目： 主持国家自然科学基金： 1）肿瘤靶向性超分子囊泡体系的设计、构筑及应用研究；2016-2019 2）基于柱芳烃聚轮烷的绝缘分子导线的合成与性质研究；2013-2015 主持江苏省基金： 1）智能超分子纳米组装体的构筑及其功能化研究；2018-2021 2）基于柱芳烃的超分子囊泡体系的构筑及其在药物转运方面的应用；2015-2017 主持德国洪堡基金项目；2016-2018 主持南京市留学人员科技创新项目（A 类）；2019.01-2019.12主持南航杰出人才培育基金项目；2019-2021