包晓峰21043副教授
博士生导师




目前就职： 环境与生物工程学院
导师类型/类别： 博士生导师
个人主页：








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联系电话：
电子邮箱： baoxiaofeng@mail.njust.edu.cn
邮编：
工作单位： 环境与生物工程学院
通讯地址：




个人信息
指导学科
社会、学会及学术
出版专著和教材
科研创新
教学活动
发表论文
指导学生情况
其他信息
获奖、荣誉称号



教育经历
2008年3月-2010年7月，美国国立卫生研究院/脑研究院(NIH/NIMH)，NIH博士后
Advisor: Dr. Victor W. Pike
2007年6月-2008年3月，美国俄亥俄州立大学医学中心/Davis心肺所，博士后
Advisor: Dr. Villamena A. Frederick
2003年8月-2007年6月，美国辛辛那提大学化学系，有机化学，博士
Advisor: Dr. David B. Smithrud
2002年8月-2003年8月，美国伊利诺伊大学芝加哥分校化工系，博士研究生
Advisor: Dr. Sohail Murad
1999年9月-2002年7月，南京理工大学化工学院，生物化工，硕士
Advisor: Professor Shulin Yang
1995年9月-1999年7月，南京理工大学化工学院，高分子化工，学士



工作经历
2013年6月-至今，南京理工大学，生物工程系，博士生导师，副教授
2011年2月-至今，南京理工大学，生物工程系，硕士生导师，副教授
2008年3月-2010年7月，美国国立卫生研究院、脑研究院，NIH博士后研究员
2007年6月-2008年3月，美国俄亥俄州立大学医学研究中心，博士后研究员
2003年8月-2007年3月，美国辛辛那提大学化学系,研究助理
2002年8月-2003年8月，美国依利诺大学芝加哥分校，助教


指导学科


社会、学会及学术兼职


出版专著和教材


科研创新

科研项目


教学活动


发表论文
2016年
1)Hai Shu, Xiaolei Wu, Baojing Zhou, Yingbin Han, Mingjie Jin, Jing Zhu* and Xiaofeng Bao*,Synthesis and evaluation of a novel fluorescent chemosensor for glutathione based on a rhodamine B and N-[4-(carbonyl) phenyl] maleimide conjugate and its application in living cell imaging, Dyes and Pigments, 2017, 136, 535-542.(IF 4.1,二区) http://dx.doi.org/10.1016/j.dyepig.2016.08.063.
2)Hailang Chen,XiaofengBao*, Hai Shu, Baojing Zhou, Renlong Yeand Jing Zhu*, Synthesis and evaluation of a novel rhodamine B-based 'off-on' fluorescent chemosensor for the selective determination of Fe³⁺ions,Sensors and Actuators B: Chemicals,doi:10.1016/j.snb.2016.09.16. (IF 4.8, 二区，Top)
3)Xiaolei Wu, Hai Shu, Baojing Zhou, Yougliang Geng, Xiaofeng Bao*, Jing Zhu*,Design and Synthesis of a New Rhodamine B-Based Fluorescent Probe for Selective Detection of Glutathione and Its Application for Live Cell Imaging, Sensors and Actuators B: Chemicals, 237, 431-442. doi:10.1016/j.snb.2016.06.161.(IF 4.8, 二区，Top)
4)Xiaofeng Bao*, Jiaxin Shi, Jing Zhu, Xinlong Wang*, A novel sensitive and selective nanocomposite sensor for Doxorubicin based on Graphene Oxide and fluorescent [2]Rotaxane, Sensors and Actuators B: Chemicals,237, 380-386.doi:10.1016/j.snb.2016.06.140. (IF 4.8, 二区，Top)
5)沈薇^*, 王林, 陈敏, 吴旻, 包晓峰^*, 芘基探针PYPA的合成及在PPi作用下对Zn2+的高效识别, 中国有机化学,Chin. J. Org. Chem. 2016, 36, 2204-2211.(IF 1.3)
6)Xiaofeng Bao*, Xiaolei Wu, Hai Shu, Qianshen Cao, and Jing Zhu* Design and synthesis of a new selective fluorescent chemical sensor for Cu²⁺based on a Pyrrole moiety and a Fluorescein conjugate,Tetrahedron Letters, 57 (8), 942-948.doi:10.1016/j.tetlet.2016.01.056. （IF 2.4）
7)Wei Shen, Lin Wang, Min Wu, Xiaofeng Bao*, A fluorescein derivative FLTC as a chemosensor for Hg²⁺and Ag+and its application in living-cell imaging, Inorganic Chemistry Communications,2016, 70, 107-110.doi:10.1016/j.inoche.2016.05.001.(IF 1.8)
2015年


1)Bao, X.*;Cao, Q.; Xu, Y.; Nie, X.; Zhou B.; Zhu, J.*,Design and synthesis of a novel chromium(III) selective fluorescent chemosensor bearing a thiodiacetamide moiety and two rhodamine B fluorophores,Sensors and Actuators B, Chemicals, 2015，221, 930-939.(IF 4.8,二区, Top)
2)Bao, X.*; Cao, X.; Nie X.; Zhou, B., Zhang, L.*; Liao, H.; Pang, T,A new selective fluorescent chemical sensor for Fe³⁺based on rhodamine B and a 1,4,7,10-tetraoxa-13-azacyclopentadecane conjugate and its imaging in living cells,Sensors and Actuators B, Chemicals2015，208, 54-56.(IF 4.8,二区, Top)
3)Shi, J.; Wang, X., Nie, X., Zhou, B., Zhu, J.*; Pang T.*,Bao X.*,Synthesis and evaluation of a novel Rhodamine B pyrene [2]rotaxane as an intracellular delivery agent for doxorubicin,Organic & Biomolecular Chemistry,2015 (13), 7517-7529. (IF 3.6)
4)Bao, X.*;Cao, Q.; Xu, Y.; Gao, Y.; Xu, Y.; Nie, X.; Zhou B.; Pang, T.; Zhu, J.*, Synthesis and evaluation of a new Rhodamine B and Di(2-picolyl) amine conjugate as a highly sensitive and selective chemosensor for Al3+ and its application in living-cell imaging.Bioorganic Medicinal Chemistry, 2015,23(4), 694-702. (IF 2.9)
5)Shi, J.; Cao, X.; Wang, X., Nie, X., Zhou, B.,Bao, X.*,Zhu, J.*, A novel switchable [2]rotaxane driven by light energy with Rhodamine B as a stopper,Tetrahedron, 2015,71 (24), 4116-4123(IF 2.8).
6) Hailang Chen, Xiaofeng Bao*, Feng Li, Baojing Zhou, Renlong Ye and Jing Zhu*,Synthesis of a new highly sensitive near-infrared fluorescentIridium(III) probe and its application for the highly selectivedetection of glutathione, RSC Adv., 2015,5, 85095-85104.(IF 3.3)

2014年

1)Bao, X.*; Jin, Y.; Liu, X.; Liao, H.; Zhang, L.; Pang, T., Synthesis and biological evaluation of XB-1 analogues as novel histamine H-3 receptor antagonists and Neuroprotective agents.RSC Advances,2014,4(13), 6761-6775. (IF 3.3)
2)Liu, D.; Pang, T.; Ma, K.; Jiang, W.;Bao, X.*, A new highly sensitive and selective fluorescence chemosensor for Cr3+ based on rhodamine B and a 4,13-diaza-18-crown 6-ether conjugate.RSC Advances2014,4(5), 2563-2567. (IF 3.3)
3)Bao, X.*; Shi, J.; Nie, X.; Zhou, B.; Wang, X.; Zhang, L.*; Liao, H.; Pang, T., A new Rhodamine B-based 'on-off' chemical sensor with high selectivity and sensitivity toward Fe3+ and its imaging in living cells.Bioorganic & Medicinal Chemistry,2014,22(17), 4826-4835. (IF 2.9).
4)Xiaofeng Bao*, Xiaowei Cao, Xuemei Nie, Yanyan Jin and Baojing Zhou,RBAP, a Rhodamine B-based Derivative: Synthesis, Crystal Structure Analysis, Molecular Simulation, and its Application as a Selective Fluorescent Chemical Sensor for Sn²⁺,Molecules, 2014,19(6), 7817-7831, ( IF 2.4)

2013年

1) Bao, X.*; Liu, D.; Jin, Y.; Liu, X.; Jiang, W., Design and synthesis of a novel Rhodamine B 2 rotaxane.RSC Advances, 2013,3(19), 6783-6786. (IF 3.3)
2) Xiaofeng Bao*, Xiaolu, Liu；Synthesis of histamine subtype 3 receptor antagonists based on a Nonimidazole 2-Aminoethylbenzofuran for prospective molecular imaging radiotracers；Journal of Labelled Compounds & Radiopharmaceuticals,2013, 56, S268-S268.（IF 1.5）
3) Xiaofeng Bao*, Yanyan Jin, Synthesisof novel acyclic non-imidazole XB-1 analoguesas precursors for H₃receptor PET radioligands,Journal of Labelled Compounds & Radiopharmaceuticals,2013, 56，S267-268.（IF 1.5）

2012年

1)Bao, X.; Lu, S.; Liow, J.-S.; Zoghbi, S. S.; Jenko, K. J.; Clark, D. T.; Gladding, R. L.; Innis, R. B.; Pike, V. W.*, Radiosynthesis and Evaluation of an F-18-Labeled Positron Emission Tomography (PET) Radioligand for Brain Histamine Subtype-3 Receptors Based on a Nonimidazole 2-Aminoethylbenzofuran Chemotype.Journal of Medicinal Chemistry,2012,55(5), 2406-15.(IF 5.6，二区, Top)
2)Bao, X.; Lu, S.; Liow, J.-S.; Morse, C. L.; Anderson, K. B.; Zoghbi, S. S.; Innis, R. B.; Pike, V. W.*, C-11 Rhodamine-123: Synthesis and biodistribution in rodents.Nuclear Medicine and Biology,2012,39(8), 1128-1136.( IF 2.5）
3)Xiaofeng Bao*, Duliang Liu, Yanyan Jin and Yao Yang；A Facile Synthesis for Novel Loperamide Analogs as Potential μ Opioid Receptor Agonists.Molecules, 2012,17, 14288-14297(IF 2.4)

2006-2011年

1)Bao, X.; Isaacsohn, I.; Drew, A. F.; Smithrud, D. B.*, Determining the intracellular transport mechanism of a cleft- 2 rotaxane.Journal of the American Chemical Society2006,128(37), 12229-12238.（IF 13.03,一区, Top)
2)Bao, X.; Isaacsohn, I.; Drew, A. F.; Smithrud, D. B.*, Determining the binding and intracellular transporting abilities of a host- 3 rotaxane.Journal of Organic Chemistry2007,72(11), 3988-4000.( IF 4.8，二区, Top)
4)Bao Xiaofeng; Lu Shuiyu; Liow Jeih-San; Victor W. Pike*,Radiolabeling and evaluation of [¹⁸F]XB-1 in monkey as a prospective histamine subtype 3 receptor PET radioligand,Journal of Labelled Compounds & Radiopharmaceuticals,2011,54 (1),S83-S83.(IF 1.5）
5)Bao Xiaofeng;Lu S.; Simeon F. G.; Victor W. Pike*;Synthesis of a prospective (18)f-labeled tracer for imaging p-glycoprotein function,Journal of Labelled Compounds & Radiopharmaceuticals; 2009, 52 ,S350-S350.(IF 1.5）
6)Bao Xiaofeng.; Morse C. L.; Lu S.; Victor W. Pike*,Synthesis of [¹¹C]Rhodamine-123 as a potential tracer for imaging p-glycoprotein function,Journal of Labelled Compounds & Radiopharmaceuticals,2009,52, S427-S427.( IF 1.5）


授权专利：
1)一种脑组胺H₃受体放射性配体的前体及其制备方法,包晓峰; 金艳艳; 刘晓露; 刘督亮; 曹小伟, 授权号：ZL2013 1 ** 3
2)一种基于罗丹明B的荧光传感器的制备及其应用，包晓峰; 曹小伟; 金艳艳; 刘督亮; 史加新，授权号: ZL 2014 1 **
3)一种基于罗丹明B的铝离子荧光传感器的制备及其应用包晓峰; 曹乾升; 曹小伟; 史加新，授权号：ZL 2014 1 ** 7
4)一种荧光化学传感器及其制备，包晓峰; 刘督亮; 金艳艳; 曹小伟; 陈晓燕，授权号: CN2.1


指导学生情况


其他信息


获奖、荣誉称号