杨先海讲师





目前就职： 环境与生物工程学院
导师类型/类别：
个人主页： http://jszy.njust.edu.cn/hjsw/yxh/list.psp








10 访问





联系电话：
电子邮箱： xhyang@njust.edu.cn
邮编： 210094
工作单位：
通讯地址： 江苏省南京市孝陵卫街200号




个人信息
指导学科
社会、学会及学术
出版专著和教材
科研创新
教学活动
发表论文
指导学生情况
其他信息
获奖、荣誉称号



教育经历
2007.9—2014.10 大连理工大学 环境工程 工学博士
2003.9—2007.07 中国石油大学（华东） 环境工程 工学学士


工作经历
2018.01-至今,南京理工大学环境与生物工程学院,讲师
2014.10-2018.01,环境保护部南京环境科学研究所,助理研究员



指导学科


社会、学会及学术兼职


出版专著和教材


科研创新

科研项目
1、可电离内分泌干扰物与运甲状腺素蛋白相互作用的计算模拟与验证,2015-2018.12.31,杨先海,国家自然科学基金青年项目,**,1



教学活动


发表论文
1、 Effects of exposure to BPF on development and sexual differentiation during early life stages of zebrafish (Danio rerio), Comp Biochem Physiol C Toxicol Pharmacol,SCI,2018,2010: 44-56,2
2、 Development of QSAR model for predicting the inclusion constants of organic chemicals with α-cyclodextrin, Environmental Science and Pollution Research,SCI,2018, doi: 10.1007/s11356-018-1917-2,2
3、 Development of chicken and fish muscle protein - Water partition coefficients predictive models for ionogenic and neutral organic chemicals, Ecotoxicology and Environmental Safety,SCI,2018, 157: 128-133,4
4、 Development of QSAR models for predicting the binding affinity of endocrine disrupting chemicals to eight fish estrogen receptor, Ecotoxicology and Environmental Safety,SCI,2018, 148: 211-219,3
5、 Effects of BPF on steroid hormone homeostasis and gene expression in the hypothalamic-pituitary-gonadal axis of zebrafish, Environmental Science and Pollution Research,SCI,2017, 24(26): 21311-21322,2
6、 Predictive models for identifying the binding activity of structurally diverse chemicals to human pregnane X receptor, Environmental Science and Pollution Research,SCI,2017, 24(24): 20063-20071,2
7、 Development of bovine serum albumin-water partition coefficients predictive models for ionogenic organic chemicals based on chemical form adjusted descriptors, Ecotoxicology and Environmental Safety,SCI,2017,144: 131-137,2
8、 Different binding mechanisms of neutral and anionic poly-/perfluorinated chemicals to human transthyretin revealed by In silico models, Chemosphere,SCI,2017,182:574 - 583,1
9、 Development of a QSAR model for predicting aqueous reaction rate constants of organic chemicals with hydroxyl radicals, Environmental Science: Processes & Impacts,SCI,2017, 19(3): 350-356,2
10、 Exposure to Bisphenol B Disrupts Steroid Hormone Homeostasis and Gene Expression in the Hypothalamic–Pituitary–Gonadal Axis of Zebrafish, Water, Air, & Soil Pollution,SCI,2017,228:112,2
11、 Development of TLSER model and QSAR model for predicting partition coefficients of hydrophobic organic chemicals between low density polyethylene film and water, Science of The Total Environment,SCI,2017, 574: 1371-1378,3
12、 Development of predictive models for predicting binding affinity of endocrine disrupting chemicals to fish sex hormone-binding globulin, Ecotoxicology and Environmental Safety,SCI,2017, 136: 46-54,2
13、 Rational Selection of 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action, Chemical Research in Toxicology,SCI,2016, 29(9):1565-1570,1
14、 Predicting anti-androgenic activity of bisphenols using molecular docking and quantitative structure-activity relationships, Chemosphere,SCI,2016, 163: 373-381,1
15、 Development of classification model and QSAR model for predicting binding affinity of endocrine disrupting chemicals to human sex hormone-binding globulin, Chemosphere,SCI,2016, 156: 1-7,2
16、 Development of Quantitative Structure-Activity Relationship Models for Predicting Chronic Toxicity of Substituted Benzenes to Daphnia Magna, Bulletin of Environmental Contamination and Toxicology,SCI,2016, 96(5): 664-670,4
17、 A DFT-based toxicity QSAR study of aromatic hydrocarbons to Vibrio fischeri: Consideration of aqueous freely dissolved concentration, Journal of Hazardous Materials,SCI,2016, 308:149-156,2
18、 Toward rational design of amines for CO2 capture: Substituent effect on kinetic process for the reaction of monoethanolamine with CO2, Journal of Environmental Sciences,SCI,2015, 37: 75-82,4
19、 In silico model for predicting soil organic carbon normalized sorption coefficient (KOC) of organic chemicals, Chemosphere,SCI,2015, 119C: 438-444,3
20、 Predicting gaseous reaction rates of short chain chlorinated paraffins with ·OH: overcoming the difficulty in experimental determination, Environmental Science & Technology,SCI,2014, 48(23): 13808-13816,4
21、 Determination and prediction of the binding interaction between organophosphate flame retardants and p53, Chemical Research in Toxicology,SCI,2014, 27(11): 1918-1925,2
22、 Molecular insights into the pH-dependent adsorption and removal of ionizable antibiotic oxytetracycline by adsorbent cyclodextrin polymers, PLoS One,SCI,2014, 9(1): e86228,6
23、 Faster photodegradation rate and higher dioxin yield of triclosan induced by cationic surfactant CTAB, Journal of Hazardous Materials,SCI,2014, 275: 210-214,4
24、 The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach, Mar Pollut Bull,SCI,2014, 85(2): 516-521,3
25、 Development of a model for predicting hydroxyl radical reaction rate constants of organic chemicals at different temperatures, Chemosphere,SCI,2014, 95: 613-618,2
26、 Development and validation of theoretical linear solvation energy relationship models for toxicity prediction to fathead minnow (pimephales promelas), Chemosphere,SCI,2014, 96:188-194,2
27、 Development of in silico models for predicting LSER molecular parameters and for acute toxicity prediction to fathead minnow (Pimephales promelas), Chemosphere,SCI,2014, 108: 17-25,2
28、 Effects of substituent position on the interactions between PBDEs/PCBs and DOM, Chinese Science Bulletin,SCI,2013, 58(8): 884-889,5
29、 Evaluating the Interactions of Organic Compounds with Multi-Walled Carbon Nanotubes by Self-Packed HPLC Column and Linear Solvation Energy Relationship, Journal of Hazardous Materials,SCI,2013, 263 (Pt 2): 550-555,5
30、 Anionic phenolic compounds bind stronger with transthyretin than their neutral forms: nonnegligible mechanisms in virtual screening of endocrine disrupting chemicals, Chemical Research in Toxicology,SCI,2013, 26(9):1340-1347,1
31、 A microbial fuel cell–electro oxidation system for coking wastewater treatment and bioelectricity generation, Journal of Chemical Technology and Biotechnology,SCI,2010, 85(5): 621-627,2
32、 国外环境内分泌干扰物管控现状及我国的对策, 生态与农村环境学报,2018,34(2): 104-113,1
33、 化学品环境暴露评估模型研究进展, 生态毒理学报,2018,13(1): 61-74,5
34、 基于CV-1细胞雌激素受体报告基因试验方法建立及双酚A类似物雌激素效应的检测,生态与农村环境学报,2017, 33 (10): 955-960,3
35、 应用物种敏感性分布评估三氯卡班对我国淡水环境的生态风险,生态与农村环境学报,2017, 33 (10): 921-927,2
36、 双酚A及其类似物对斑马鱼成鱼及胚胎的急性毒性,生态与农村环境学报,2017,33(4)：372-378,3
37、 双酚A及其类似物对斑马鱼胚胎及幼鱼的毒性效应, 生态毒理学报,2017, 12(1): 184-192,4
38、 四溴双酚A和2,4,6-三溴苯酚对黄颡鱼的内分泌干扰毒性效应, 生态与农村环境学报,2016, 06: 1012-1017,4
39、 双酚A类似物雌激素干扰效应的定量结构-活性关系模型, 生态毒理学报,2016, 11(4): 69-78,1
40、 化学品甲状腺干扰效应的计算毒理学研究进展, 科学通报,2015, 60(19): 1761-1770,1
41、 含卤有机化合物与甲状腺素转运蛋白相互作用的卤代效应, 科学通报,2014,59(27): 2673-2680,1
42、 卤代有机化合物生物富集因子的定量结构-活性关系模型, 生态毒理学报,2013, 8(5): 772-777,3
43、 乙腈溶剂中单壁碳纳米管与常见有机化合物的相互作用, 环境化学,2013, 32(7): 1277-1282,3
44、 有机防晒剂在水环境中的光化学行为, 科学通报,2013, 58(30): 2989-3006,2
45、 有机污染物生物降解性预测模型, 生态毒理学报,2012, 7(5):549-555,3



指导学生情况


其他信息


获奖、荣誉称号
1、微生物燃料电池-电氧化系统处理焦化废水与电能输出,大连理工大学,黄丽萍，杨先海，全燮，陈景文,2011,辽宁省自然科学学术成果奖,二等奖