博士研究生导师简介
姓名
朱维铭
研究方向：
胃肠外科


联系方式
juwiming@nju.edu.cn

学术兼职：
中华医学会外科学分会胃肠外科学组委员
中华医学会消化病分会炎症性肠病学组顾问
中华医学会肠外肠内营养学分会胃肠病与营养协作组组长
江苏省医学会外科学分会委员

个人简介

医学博士、主任医师、教授、博士生导师
南京大学医学院附属金陵医院普通外科主任
擅长复杂胃肠外科、炎症性肠病综合治疗及临床营养支持治疗。

代表性论文[近5年通讯作者和第一作者]

Li, Y, Mohan, H, Lan, N. et al. Mesenteric excision surgery or conservative limited resection in Crohn’s disease: study protocol for an international, multicenter, randomized controlled trial.[J].Trials,2020 Feb 21;21(1):210. doi: 10.1186/s13063-020-4105-x.
Ruiqing L , Shuaihua Q , Weisong S , et al. Disturbance of Fatty Acid Desaturation Mediated by FADS2 in Mesenteric Adipocytes Contributes to Chronic Inflammation of Crohn's Disease[J]. Journal of Crohn's and Colitis.2020 May 4;jjaa086. doi: 10.1093/ecco-jcc/jjaa086.
Xu Y, Guo Z, Huang L, et al. A nomogram for predicting the response to exclusive enteral nutrition in adult patients with isolated colonic Crohn’s disease[J]. Therapeutic advances in gastroenterology, 2019, 12: **81301.
Xu Y, Guo Z, Cao L, et al. Isolated colonic Crohn's disease is associated with a reduced response to exclusive enteral nutrition compared to ileal or ileocolonic disease[J]. Clinical Nutrition, 2019, 38(4): 1629-1635.
Liu R, Guo Z, Cao L, et al. Profile of Consecutive Fecal Calprotectin Levels in the Perioperative Period and Its Predictive Capacity for Early Endoscopic Recurrence in Crohn’s Disease[J]. Diseases of the Colon & Rectum, 2019, 62(3): 318-326.
Shen W, Li Y, Zou Y, et al. Mesenteric Adipose Tissue Alterations in Crohn’s Disease Are Associated With the Lymphatic System[J]. Inflammatory Bowel Diseases, 2019, 25(2): 283-293.
Shen W, Li Y, Cao L, et al. Decreased Expression of Prox1 Is Associated With Postoperative Recurrence in Crohn’s Disease[J]. Journal of Crohn's and Colitis, 2018, 12(10): 1210-1218.
Shen W, Cao L, Li Y, et al. Visceral fat is associated with mucosal healing of infliximab treatment in Crohn’s disease[J]. Diseases of the Colon & Rectum, 2018, 61(6): 706-712.
Ge Y, Li Y, Chen Q, et al. Adipokine apelin ameliorates chronic colitis in Il-10?/? mice by promoting intestinal lymphatic functions[J]. Biochemical pharmacology, 2018, 148: 202-212.
Guo Z, Cai X, Guo X, et al. Let-7b ameliorates Crohn’s disease-associated adherent-invasive E coli induced intestinal inflammation via modulating Toll-Like Receptor 4 expression in intestinal epithelial cells[J]. Biochemical pharmacology, 2018, 156: 196-203.
Li Y, Ge Y, Gong J, et al. Mesenteric lymphatic vessel density is associated with disease behavior and postoperative recurrence in Crohn’s disease[J]. Journal of Gastrointestinal Surgery, 2018, 22(12): 2125-2132.
Cai X, Shen W, Guo Z, et al. Thickness of Subcutaneous Fat Is a Predictive Factor of Incisional Surgical Site Infection in Crohn’s Disease Surgery: A Retrospective Study[J]. Gastroenterology research and practice, 2018, 2018.
Li Y, Ge Y, Zhu W, et al. Increased enteric glial cells in proximal margin of resection is associated with postoperative recurrence of Crohn's disease[J]. Journal of gastroenterology and hepatology, 2018, 33(3): 638-644.
Guo Z, Cao L, Guo F, et al. The presence of postoperative infectious complications is associated with the risk of early postoperative clinical recurrence of Crohn’s disease[J]. World journal of surgery, 2017, 41(9): 2371-2377.
Li Y, Zhu W, Gong J, et al. The role of the mesentery in Crohn's disease[J]. The Lancet Gastroenterology & Hepatology, 2017, 2(4): 244-245.
Guo F, Huang Y, Zhu W, et al. Efficacy and safety of endoscopic balloon dilation for upper gastrointestinal strictures of Crohn’s disease[J]. Digestive diseases and sciences, 2016, 61(10): 2977-2985.
Li Y, Tian Y, Zhu W, et al. IL-10/microRNA-155/SHIP-1 signaling pathway is crucial for commensal bacteria induced spontaneous colitis[J]. Biochemical pharmacology, 2016, 116: 100-106.
Guo Z, Gong J, Li Y, Gu L, Cao L, Wang Z, Zhu W, Li J. Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn’s Disease. [J]Nutrients, 2016, 8(8): 519.
Gong J, Xie Z, Zhang T, Gu L, Yao W, Guo Z, Li Y, Lu N, Zhu W, Li N, Li J. Randomised clinical trial: prucalopride, a colonic pro‐motility agent, reduces the duration of post‐operative ileus after elective gastrointestinal surgery. [J] Alimentary pharmacology & therapeutics, 2016, 43(7): 778-789
Gong J, Wei Y, Gu L, Li Y, Guo Z, Sun J, Ding C, Zhu W, Li N, Li J Outcome of Surgery for Coloduodenal Fistula in Crohn’s Disease. [J]Journal of Gastrointestinal Surgery, 2016, 20(5): 976-984.
Zuo L, Li Y, Zhu W, Shen B, Gong J, Guo Z, Zhang W, Wu R, Gu L, Li N, Li J. Mesenteric adipocyte dysfunction in Crohn's disease is associated with hypoxia. [J]Inflammatory bowel diseases, 2016, 22(1): 114-126.
Li Y, Zhu W, Zuo L, et al. The Role of the Mesentery in Crohn's Disease: The Contributions of Nerves, Vessels, Lymphatics, and Fat to the Pathogenesis and Disease Course[J]. Inflammatory bowel diseases, 2016, 22(6): 1483-1495.
Sun J, Shen X, Li Y, et al. Therapeutic Potential to Modify the Mucus Barrier in Inflammatory Bowel Disease[J]. Nutrients, 2016, 8(1): 44.
Wang H, Zuo L, Zhao J, et al. Impact of Preoperative Exclusive Enteral Nutrition on Postoperative Complications and Recurrence After Bowel Resection in Patients with Active Crohn’s Disease[J]. World Journal of Surgery, 2016, 40(8): 1993-2000.
Wang H, Shi P, Zuo L, et al. Dietary non-digestible polysaccharides ameliorate intestinal epithelial barrier dysfunction in IL-10 knockout mice[J]. Journal of Crohn's and Colitis, 2016, 10(9): 1076-1086.
Guo Z, Guo D, Gong J, et al. Preoperative nutritional therapy reduces the risk of anastomotic leakage in patients with Crohn’s disease requiring resections[J]. Gastroenterology Research and Practice, 2016, 2016.

承担科研项目[项目负责人]


国家自然科学基金面上项目(**) 肠系膜脂肪细胞功能障碍在克罗恩病中的意义及HIF通路的调节作用(2018-2021)，课题经费：56万元
国家自然科学基金面上项目(**)基于肠系膜淋巴内皮细胞探讨脂肪因子Apelin在克罗恩病中的作用及意义(2016-2019)，课题经费：68.3万元
国家自然科学基金面上项目(**)应用CD52单抗(Campath)选择性清除淋巴细胞对克罗恩病的干预作用及其机制研究(2012-2015)，课题经费：60万元



获奖情况

以第一或第二贡献者身份获得省部级科技进步一等奖2项，二等奖2项，2010年国家科技进步一等奖《肠功能障碍的治疗》主要完成人之一。首届裘法祖普通外科医学青年奖获得者。