博士研究生导师简介
姓名
徐标
研究方向：
心血管疾病的再生医学、心血管疾病介入治疗


联系方式
**

学术兼职：
国际心脏研究协会委员
美国心脏病学会委员（FACC）
美国心血管造影和介入学会委员（FSCAI）
中国医师协会整合心血管病学会副主任委员
中国医疗保健国际交流促进会心血管病分会常务委员
中国高血压联盟常务委员
海峡两岸医药卫生交流协会心血管专业委员会常务委员
中华医学会实用介入技术推广培训中心副主任委员
中华医学会心血管病学分会委员
中华医学会心血管病学分代谢学组副组长
中国老年医学学会心血管病分会委员
江苏省医学会心血管病学分会主任委员
江苏省医师协会心血管内科医师分会候任会长
江苏省中西医结合学会心血管分会副主任委员

个人简介

徐标，FACC、FSCAI，主任医师、教授、博士生导师，心脏科行政主任。江苏省医学重点人才，享受国家政府特殊津贴，中国医师协会整合心血管病学会副主任委员，海峡两岸医药卫生交流协会心血管病专业委员会常委，中国医疗保健国际交流促进会心血管病分会常务委员，中国高血压联盟常委，中华医学会心血管病学分会委员，中华医学会心血管学分会代谢学组副组长，江苏省医学会心血管病学分会主任委员，江苏省医师协会心血管内科医师分会候任会长，江苏省中西医结合学会心血管分会副主任委员，卫生部心血管介入技术冠心病培训基地主任，Circulation，Circulation Research，J hypertension，ATVB，IJBM等SCI期刊的特约审稿人，兼任《中华高血压杂志》、《中国动脉硬化杂志》、《中华现代内科学杂志》等编委。擅长心血管危重病、冠心病、高血压、心力衰竭等疾病的诊治，在江苏省首先开展了冠心病介入诊断和治疗手术。在急诊PCI术、复杂冠脉介入诊疗、先天性心脏病介入治疗方面有丰富的经验，是国内知名冠心病介入专家。先后主持国家自然科学基金项目研究7项，省级科研项目20余项。发表论文300余篇，SCI收录100篇以上，其中两篇发表在《Circulation》杂志上，影响因子达23.603，还有二篇论文发表在《Ann Inter Med 》，影响因子17.2分, 一些论文被ESC的指南引用。其带领的团队曾获得其带领的团队曾获得“江苏省医学重点学科”称号、“江苏省科技创新团队”称号、中华医学科技三等奖、中国杰出心血管病研究奖、江苏医学科技一等奖、江苏省新技术引进一等奖、江苏省科技进步二等奖、江苏省科技进步三等奖、南京市科技进步二等奖等多个奖项。

代表性论文[近5年通讯作者和第一作者]

XuanSun， ZilunWei， YuyuLi， JunzhuoWang，JiaxinHu，YongYin，JunXie，BiaoXu.Renal denervation restrains the inf ammatory response in myocardial ischemia–reperfusion injury.Basic Research In Cardiology， (2020) 115:15.
JunzhuoWang，ZiweiChen，QingDai，JinxuanZhao，ZilunWei，JiaxinHu，XuanSun，JunXie，BiaoXu.Intravenously delivered mesenchymal stem cells prevent microvascular obstruction formation after myocardial ischemia/reperfusion injury.Basic Research In Cardiology， (2020) 115:40.
Xin-Lin Zhang,Xiao-Wen Zhang, Rong-Fang Lan, Zheng Chen, Lian Wang, Wei Xu, and Biao Xu.Long-term and Temporal Outcomes of Transcatheter Versus Surgical Aortic-valve Replacement in Severe Aortic Stenosis: A Meta-analysis.Annals of Surgery.2020 Jun 3.
Zilun Wei, Yining Yang ,Qiaoling Li, Yong Yin，Zhonghai Wei, Wenfeng Zhang, Dan Mu,Jie Ni，Xuan Sun,Biao Xu.The transcriptome of circulating cells indicates potential biomarkers and therapeutic targets in the course of hypertension-related myocardial infarction.Genes & Diseases，2020（IF=4.803）
Jinxuan Zhao, Xueling Li, Jiaxin Hu, Fu Chen, Shuaihua Qiao, Xuan SunLing Gao, Jun Xie, and Biao XuMesenchymal stromal cell-derived exosomes attenuate myocardial ischaemia-reperfusion injury through miR-182-regulated macrophage polarization.Cardiovasc Res.2019;115(7):1205-1216
Hai Cheng,, Yuhan Chen, Xueling Li, Fu Chen, Jinxuan Zhao,Jiaxin Hu, Anqi Shan, Shuaihua Qiao,Zilun Wei, Guixin He andBiao Xu.Involvement of Apelin/APJ Axis in Thrombogenesis in Value Heart Disease Patient with Atrial Fibrillation.International Heart Journal.2019,60(1):145-150
Wei Zilun, Qiao Shuaihua, Zhao Jinxuan, Liu Yihai, Li Qiaoling, Wei Zhonghai,Dai Qing, Kang Lina, Xu Biao.miRNA-181a over-expression in mesenchymal stem cell-derived exosomes influenced inflammatory response after myocardial ischemia-reperfusion injury.Life Sciences.2019 Sep 1;232:116632.
Zhong-Hai WEI, Wen-Zhi SHEN, Jian BAI, Jun XIE, Wen-Qing JI, Lian WANG, Wei XU,Biao XU.Treatment of refractory ventricular tachycardia with combination of alcohol ablation and radiofrequency ablation.Journal of Geriatric Cardiology.2019(16):660-662.
Xin-Lin Zhang ,Rong-Fang Lan,Xiao-Wen Zhang,Wei Xu ,Lian Wang ,Li-Na Kang,Biao Xu.Association Between Baseline, Achieved, and Reduction of CRP and Cardiovascular Outcomes After LDL Cholesterol Lowering with Statins or Ezetimibe: A Systematic Review and Meta-Analysis.J Am Heart Assoc.2019;8:e012428.
Xinlin Zhang,Tingyu Wang,Rongfang Lan,Qing Dai,Lina Kang,Lian Wang,Yong Wang,Wei Xu,Biao Xu.Meta-Analysis Comparing Results of Transcatheter Versus Surgical Aortic-Valve Replacement in Patients WithSevereAortic Stenosis.Am J Cardiol.00:1?10.
Xueling Li,Jinxuan Zhao,Jin Geng,Fu Chen,Zilun Wei,Chen Liu,Xinlin Zhang,Qiaoling Li,Jingmei Zhang,Ling Gao,Jun Xie,Biao Xu.Long non-coding RNA MEG3 knockdown attenuates endoplasmic reticulum stress-mediated apoptosis by targeting p53 following myocardial infarction.J Cell Mol Med.2019 Dec;23(12):8369-8380.
Zhong-Hai Wei,Wen-Zhi Shen,Jian Bai,Jun Xie,Wen-Qing Ji,Lian Wang,Wei Xu,Biao Xu.Treatment of refractory ventricular tachycardia with combination of alcohol ablation and radiofrequency ablation. J Geriatr Cardiol..2019 Aug;16(8):660-662.
Jin Geng,Haiyun Liu,Peibing Ge,Tingting Hu,Yanchun Zhang,Xiwen Zhang,Biao Xu,Bingjian Wang,Jun Xie.PM2.5 promotes plaque vulnerability at different stages of atherosclerosis and the formation of foam cells via TLR4/MyD88/NFκB pathway.Ecotoxicol Environ Saf.2019 Jul 30;176:76-84.
Qinhua Chen,Ryan C Gimple,Guannan Li,Jianzhou Chen,Han Wu,Ran Li,Jun Xie,Biao Xu.LIM kinase 1 acts as a profibrotic mediator in permanent atrial fibrillation patients with valvular heart disease. J Biosci.2019 Mar;44(1). pii: 16.
Kun Wang,Jingmei Zhang,Ning Zhang,Yu Shen,Lian Wang,Rong Gu,Biao Xu,Yong Ji Combined Primary PCI with Multiple Thrombus Burden Reduction Therapy Improved Cardiac Function in Patients with Acute Anterior Myocardial Infarction.Int Heart J.2019 Jan 25;60(1):27-36.
Zilun Wei,Yihai Liu,Shuaihua Qiao,Xueling Li,Qiaoling Li,Jinxuan Zhao,Jiaxin Hu,Zhonghai Wei,Anqi Shan,Xuan Sun,Biao Xu.Identification of the potential therapeutic target gene UBE2C in human hepatocellular carcinoma: An investigation based on GEO and TCGA databases.Oncology Letters.2019;17(6):5409-5418.
Han Wu,Zheng Chen,Jian-Zhou Chen,Jun Xie,andBiao Xu.Resveratrol Improves Tube Formation in AGE-Induced Late Endothelial Progenitor Cells by Suppressing Syndecan-4 Shedding. Oxid Med Cell Longev. 2018; 2018: **.
Jun X, Jin G, Fu C, Jinxuan Z, Xuelin L, Jiaxin H, Shuaihua Q, Anqi S, Jianzhou C, Lian Z, Xiwen Z, Baoli Z, Biao X.PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice. Biomed Pharmacother.2018 Aug;104:550-557.
Wei ZH, Dai Q, Wu H, Song J, Wang L, Xu B.Takotsubo cardiomyopathy after pacemaker implantation.J Geriatr Cardiol. 2018 Mar;15(3):246-248.
Wang K, Shen Y, Li PW, Gu R, Zhang JM, Wang L, Bai J, Xu B.ST-Segment Elevation Myocardial Infarction Patients Complicated by Out-of-Hospital Cardiac Arrest May Not Benefit from Emergency Percutaneous Intervention.Chin Med J (Engl). 2018 Mar 20;131(6):746-747.
Zhang XL, Kang LN, Wang L, Xu B.Percutaneous closure versus medical therapy for stroke with patent foramen Ovale: a systematic review and meta-analysis.BMC Cardiovasc Disord. 2018 Mar 2;18(1):45.
Zhang XW, Zhang XL, Xu B, Kang LN.Comparative safety and efficacy of insulin degludec with insulin glargine in type 2 and type 1 diabetes: a meta-analysis of randomized controlled trials.Acta Diabetol. 2018 May;55(5):429-441.
Hu L, Yao X, Huang H, Guo Z, Cheng X, Xu Y, Shen Y, Xu B, Li D.Clinical significance of germline copy number variation in susceptibility of human diseases.J Genet Genomics. 2018 Jan 20;45(1):3-12.
Di W, Lv J, Jiang S, Lu C, Yang Z, Ma Z, Hu W, Yang Y, Xu B.PGC-1: The Energetic Regulator in Cardiac Metabolism.Curr Issues Mol Biol. 2018 Feb 1;28:29-46.
Qing Dai, Jie Song, Jian He, Biao Xu.Rare Case of Anomalous Original Left Circumflex Artery Stenosis After Artificial Mitral Valve Replacement. JACC: Cardiovascular Interventions. 2017 Apr 10;10(7):e71-e73.
Xin-Lin Zhang, Qing-Qing Zhu, Jing-Jing Yang, Yu-Han Chen, Yang Li, Su-Hui Zhu, Jun Xie, Lian Wang,Li-Na Kangand Biao Xu.Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis.BMC Medicine.2017 Apr 21;15(1):84.
Xinlin Zhang, Jun Xie, Suhui Zhu, Yuhan Chen, Lian Wang, Biao Xu.Next-generation sequencing identifies pathogenic and modifier mutations in a consanguineous Chinese family with hypertrophic cardiomyopathy.Medicine.96(24): p. e7010.
Xin-Lin Zhang, Qing-Qing Zhu, Li-Na Kang, Xue-Ling Li, and Biao Xu.Mid- and Long-Term Outcome Comparisons of Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents: A Systematic Review and Meta-analysis.Annals of Internal Medicine.2017，167（9）：642-654.
Xin-Lin Zhang, Biao Xu.Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement.Annals of Internal Medicine.2017，166（8）：605.
Guannan Li, Jun Xie, Jianzhou Chen, Ran Li, Han Wu, Xinlin Zhang, Qinhua Chen, Rong Gu , Biao Xu.Syndecan-4 deficiency accelerates the transition from compensated hypertrophy to heart failure following pressure overload.Cardiovascular Pathology.May-June，2017 Volume 28，Pages74–79.
Guannan Li, Jianzhou Chen, Xinlin Zhang, Guixin He, Wei Tan, Han Wu, Ran Li,Yuhan Chen, Rong Gu, Jun Xie & Biao Xu.Cardiac repair in a mouse model of acute myocardial infarction with trophoblast stem cells.Scientific Reports.2017 Mar 15;7:44376.
Jun Xie, Yuhan Chen, Chuanxian Hu, Quanhua Pan, Bingjian Wang, Xueling Li, Jin GengandBiao Xu.Premature senescence of cardiac fibroblasts and atrial fibrosisin patients with atrial fibrillation.Oncotarget. 2017, 8(35)：57981-57990.
Xueling Li, Jin Geng, Yuhan Chen, Fu Chen, Chen Liu, Qiwen Xu, Jinxuan Zhao,Jiaxin Hu, Jun Xie, Biao Xu.Exposure to particulate matter induces cardiomyocytes apoptosis after myocardial infarction through NFkB activation.Biochem Biophys Res Commun.2017 Jun 17;488(1):224-231.
Jun Xie, Suhui Zhu, Qing Dai, Jianrong Lu, Jianzhou Chen, Guannan Li, Han Wu, Ran Li, Wei Huang, Biao Xu, Wei Xu,.Oncostatin M was associated with thrombosis in patients with atrial fibrillation.Medicine.(2017) 96:18(e6806)
Gui-xin He,Jun XieHao,JiangWeiTan,Biao Xu.Effects of Qishen Yiqi Dripping Pills () in reducing myocardial injury and preserving microvascular function in patients undergoing elective percutaneous coronary intervention: A pilot randomized study.Chin J Integr Med.2017May 3.
Wen Lu,Jun Xie, Rong Gu,and Biao Xu.Expression of integrin-linked kinase improves cardiac function in a swine model of myocardial infarction.Exp Ther Med.2017May;13(5):1868-1874
Jin Geng, Yanchun Zhang, Bingjian Wang, Jun Xie, Biao Xu, Ju Li.Glycosylated hemoglobin levels and clinical outcomes in nondiabetic patients with coronary artery disease.Medicine (Baltimore).2017 Apr; 96(17): e6784.
Yang Li, Jing-Jing Yang, Su-Hui Zhu, Biao Xu,Lian Wang.Long-term efficacy and safety of carotid artery stenting versus endarterectomy: A meta analysis of randomized controlled trials.PLOS ONE.2017 Jul 14;12(7):e**.
Jun Xie,Ran Li,Han Wu,Jian-Zhou Chen,Guan-Nan Li,Qin-Hua Chen,Zhong-Hai Wei,Gui-Xin He,Lian Wang,Albett Ferro,Biao Xu.Advanced Glycation Endproducts Impair Endothelial Progenitor Cell Migration and Homing via Syndecan 4 Shedding.Stem Cells.2017,35（2）:522-531.
Xin-Lin Zhang, Biao Xu.Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stents. Annals of Internal Medicine. 2016 Dec 6;165(11):829. doi: 10.7326/L16-0419.
Jiang C, Zhu W, Yan X, Shao Q, Xu B, Zhang M, Gong R.Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury tochronic kidney disease via targeting GSK3β. Sci Rep. 2016 Nov 18;6:36698. doi: 10.1038/srep36698.
HanWu, Zheng Chen, Jun Xie, Li-Na Kang, LianWang, and Biao Xu.High Mobility Group Box-1: A Missing Link between Diabetes and Its Complications. Mediators Inflamm. olume 2016, Article ID **, 11 pages.
Han Wu,Zhen-Qiang Sheng,Jun Xie,Ran Li,Liang Chen,Guan-Nan Li,LianWang,and Biao Xu.Reduced HMGB 1-Mediated Pathway and Oxidative Stress in Resveratrol-Treated Diabetic Mice: A Possible Mechanism of Cardioprotection of Resveratrol in Diabetes Mellitus. Oxid Med Cell Longev. Volume 2016, Article ID **, 10 pages.
Zhonghai Wei,Jun Xie,Kun Wang,Lina Kang , Qing Dai ,Jian Bai, Biao Xu .Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft in Aged Patients With Unprotected Left Main Artery Lesions.. International Heart Journal. 2016,57(6):682-688.
Li L, Lopes J, Zhou JY,Xu B. Integrating Medical Simulation Into the Physician Assistant Physiology Curriculum. J Physician Assist Educ. 2016 Dec;27(4):156-161.
Ran Li,Han Wu ,Jun Xie ,Guannan Li ,Rong Gu ,Lina Kang ,Lian Wang,Biao Xu.Syndecan-4 regulates the bFGF-induced chemotactic migration of endothelial cells. J Mol Histol. 2016 Oct;47(5):503-9. doi: 10.1007/s10735-016-9693-0.
Li SN, Zhang XL, Cai GL, Lin RW, Jiang H, Chen JZ,Xu B,Huang W.Prognostic Significance of Frontal QRS-T Angle in Patients with Idiopathic Dilated Cardiomyopathy. Chin Med J (Engl). 2016 Aug 20;129(16):1904-11. doi: 10.4103/0366-6999.187844.
24.Zhonghai Wei, Jie Song, Xuebing Feng, Ning Zhang, LianWang, Biao Xu. Reversal of cardiac remodeling after treatment of IgG4 related cholangitis.International Journal of Cardiology, 2016,222:257–259.
Zhonghai Wei, Xinlin Zhang, Han Wu, Jun Xie, Qing Dai,Lian Wang, Biao Xu. A meta-analysis for efficacy and safety evaluation of transcatheter left atrial appendage occlusion inpatients with nonvalvular atrial fibrillation.Medicine, 2016,95(31):e4382
Geng J, Ye X, Liu C, Xie J, Chen J, Xu B,Wang B.Outcomes of off- and on-hours admission in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: A retrospective observational cohort study. Medicine (Baltimore). 2016 Jul;95(27):e4093. doi: 10.1097.
Sun J,Xie J,Kang L,Ferro A,Dong L,Xu B.Amlodipine Ameliorates Ischemia-Induced Neovascularization in Diabetic Rats through Endothelial Progenitor Cell Mobilization. Biomed Res Int. 2016;2016:**. doi: 10.1155/2016/**.
Jiang C,Zhu W,Shao Q,Yan X,Jin B,Zhang M,Xu B.Tanshinone IIA Protects Against Folic Acid-Induced Acute Kidney Injury..Am J Chin Med2016;44(4):737-53.
Han Wu, Liang Chen, Jun Xie, Ran Li, Guan-nan Li, Qin-Hua Chen, Xin-Lin Zhang, Li-Na Kang and Biao Xu.Periostin expression induced by oxidative stress contributes to myocardial fibrosis in a rat model of high salt-induced hypertension. Mol Med Rep. 14: 776-782, 2016.
Li J, Li Y,Xu B, Jia G, Guo T, Wang D, Xu K, Deng J, Han Y.Short-term rosuvastatin therapy prevents contrast-induced acute kidney injury in female patients with diabetes and chronic kidney disease: a subgroup analysis of the TRACK-D study. J Thorac Dis. 2016 May;8(5):1000-6. doi: 10.21037/jtd.2016.03.26.
Zhonghai Wei, Lian Wang, Jun Xie, Wei Huang, Lina Kang, Kun Wang, Jingmei Zhang, Jie Song, Biao Xu.The therapeutic effect of rotational atherectomy with implantation of drug eluting stent in heavily coronary calcified patients. Journal of Geriatric Cardiology,2016,13:233-238
Xin-Lin Zhang,Li Zhu,Zhong-HaiWei, Qing-Qing Zhu,Jian-Zhong Qiao, Qing Dai, Wei Huang, Xiao-Hong Li, Jun Xie, Li-Na Kang, LianWang, and Biao Xu.Comparative Efficacy and Safety of Everolimus-Eluting ioresorbable Scaffold Versus Everolimus-Eluting Metallic Stents. Annals of Internal Medicine. 2016 Jun 7;164(11):752-63. doi: 10.7326/M16-0006.
Li R,Xie J,Wu H,Li G,Chen J,Chen Q,Wang L,Xu B. Syndecan-4 shedding impairs macrovascular angiogenesis in diabetes mellitus. Biochem Biophys Res Commun. 2016 May 20;474(1):15-21. doi: 10.1016/j.bbrc.2016.03.112.
Guixin He,Wei Tan, BingjianWang, Jianzhou Chen, Guannan Li, Suhui Zhu,Jun Xie, Biao Xu.Increased M1 Macrophages Infiltration Is Associated with Thrombogenesis in Rheumatic Mitral Stenosis Patients with Atrial Fibrillation.PloS One. 2016 Mar 1;11(3):e**. doi: 10.1371/journal.pone.**.
Qiaoling Li, Jun Xie, BingjianWang, Ran Li, Jian Bai, Liang Ding, Rong Gu,LianWang, Biao Xu.Overexpression of microRNA-99a Attenuates Cardiac ypertrophy. PLoS One. 2016 Feb 25;11(2):e**.
Jun Xie, Guixin He, Qinhua Chen, Jiayin Sun, Qin Dai, Jianrong Lu, Guannan Li, Han Wu, Ran Li,Jianzhou Chen, Wei Xu, and Biao Xu.Syndecan 4 signaling is required for exercise-induced cardiac hypertrophy. Mol Med. 2016 Jan 21. doi: 10.2119/molmed.2015.00026.
HanWu, Ran Li, Zhong-HaiWei, Xin-Lin Zhang, Jian-Zhou Chen,Qing Dai, Jun Xie, and Biao Xu.Diabetes-Induced Oxidative Stress in Endothelial Progenitor Cells May Be Sustained by a Positive Feedback Loop Involving High Mobility Group Box-1. Oxid Med Cell Longev. 2016;2016:**.
Han Wu , Guan-Nan Li , Jun Xie, Ran Li, Qin-Hua Chen, Jian-Zhou Chen, Zhong-Hai Wei, Li-Na Kang andBiao Xu.Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice. BMC Cardiovasc Disord. (2016) 16:5.
Dan Mu, Xin-Lin Zhang, Jun Xie, Hui-Hua Yuan, Kun Wang, Wei Huang, Guan-Nan Li, Jian-Rong Lu, Li-Juan Mao, Lian Wang, Le Cheng, Xiao-Li Mai, Jun Yang, Chuan-Shuai Tian, Li-Na Kang, Rong Gu, Bin Zhu & Biao Xu.Intracoronary Transplantation of Mesenchymal Stem Cells with Overexpressed Integrin-Linked Kinase Improves Cardiac Function in Porcine Myocardial Infarction. Sci Rep. 2016 Jan 11;6:19155. doi: 10.1038/srep19155.
Zheng K,Lu H,Sheng Z,Li Y,Xu B.Low-concentration of perifosine surprisingly protects cardiomyocytes from oxygen glucose deprivation. Biochem Biophys Res Commun. Biochem Biophys Res Commun. 2016 Jan 15;469(3):753-60. doi: 10.1016/j.bbrc.2015.12.014.
Qiao J(1), Zhang X, Zhang J, Li P, Xu B, Wang S, Jiang H, Shen Y, Wang K.Comparison between Fondaparinux and Low-Molecular-Weight Heparin in Patients with Acute Coronary Syndrome: A Meta-Analysis. Cardiology. 2016;133(3):163-72. doi: 10.1159/. Epub 2015 Nov 26.
Jiang C, Shao Q, Jin B, Gong R, Zhang M, Xu B.Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment. Biomed Res Int. 2015;2015:867140. doi: 10.1155/2015/867140. Epub 2015 Dec 29.
Wei Zhonghai, Song Jie, Wang Lian, Zhang Jingmei, Huang Wei, Xu Biao.Therapeutic effect of interventional therapy for unprotected left main coronary artery lesions in aged patients. Journal of Geriatric Cardiology.. 2015, 12(6):634-640.doi:10.11909/j.issn.1671-5411.
Wang BJ, Liu J, Geng J, Zhang Q, Hu TT,Xu B.Association between three interleukin-10 gene polymorphisms and coronary artery disease risk: a meta-analysis. Int J Clin Exp Med. 2015 Oct 15;8(10):17842-55. eCollection 2015.
Xiong Y, Wang L, Liu W, Hankey GJ,Xu B, Wang S.The Prognostic Significance of Right Bundle Branch Block: A Meta-analysis of Prospective Cohort Studies. Clin Cardiol. 2015 Oct;38(10):604-13. doi: 10.1002/clc.22454. Epub 2015 Oct 5.
Xin-lin Zhang,Qing-qing Zhu,Li -Zhu,He Jiang,Jun Xie,Wei Huang,Biao Xu.Spatial/Frontal QRS-T Angle Predicts All-Cause Mortality and Cardiac Mortality:A Meta-Analysis. Plos one. 2015;10(8):e**.
Han Wu, Jun Xie, Guan-Nan Li, Qin-Hua Chen, Ran Li, Xin-Lin Zhang, Li-Na Kang, Biao Xu.Possible involvement of TGF-β/periostin in fibrosis of right atrial appendages in patients with atrial fibrillation. Int J Clin Exp Pathol. 2015;8(6):6859-6869.
Han Wu, Qing Zhou, Jun Xie, Guan-Nan Li, Qin-Hua Chen, Li-Na Kang, Biao Xu.Syndecan-4 shedding is involved in the oxidative stress and inflammatory responses in left atrial tissue with vavular atrial fibrillation. Int J Clin Exp Pathol. 2015;8(6):6387-6396.
Xin-Lin Zhang, Qing-Qing Zhu, Li Zhu, Jian-Zhou Chen, Qin-Hua Chen, Guan-Nan Li, Jun Xie,Li-Na Kang and Biao Xu.Safety and efficacy of anti-PCSK9 antibodies：a meta-analysis of 25 randomized，controlled trials. BMC Medicine. (2015)13:123.doi: 10.1186/s12916-015-0358-8.
Shang Wang, Lijuan Yang, Lian Wang, Ling Gao, Biao Xu, Yunyun Xiong.Selective Serotonin Reuptake Inhibitors (SSRIs) and the Risk of Congenital Heart Defects: A Meta-Analysis of Prospective Cohort Studies. Journal of the American Heart Association. 2015 May 19;4(5). pii: e001681. doi: 10.1161/JAHA.114.001681.
Qiaoling Li, Tingting Hu, Liang Chen, Jiayin Sun, Jun Xie,Rang Li and Biao Xu.Selection of reference genes for normalization of quantitative polymerase chain reaction data in mouse models of heart failure. molecular medicine reports. 11: 393-399, 2015.
Qing-Qing Zhu, Xin-Lin Zhang, Si-Min Zhang, Shao-Wen Tang,Hai-Yan Min, Long Yi, Biao Xu,and Yong Song.Association Between the MUC5B Promoter Polymorphism rs** and ldiopathic Pulmonary Fibrosis. Medicine. 94（43）,2015.
Dan Mu,Xin-Lin Zhang, Jun Xie, Hui-Hua Yuan, Kun Wang, Wei Huang, Guan-Nan Li, Jian-Rong Lu, Li-Juan Mao, Lian Wang, Le Cheng, Xiao-Li Mai, Jun Yang,Chuan-Shuai Tian, Li-Na Kang, Rong Gu, Bin Zhu & Biao Xu.Intracoronary Transplantation of Mesenchymal Stem Cells with Overexpressed Integrin-Linked Kinase Improves Cardiac unction in Porcine Myocardial Infarction. Scientific RepoRts. 2015，5:19155 | DOI: 10.1038/srep19155.
Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, K?ber LV, Lawson FC, Ping L, Wei X, Lewis EF, Maggioni AP, McMurray JJ, Probstfield JL, Riddle MC, Xu B, Et.al.Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome. N Engl J Med. 2015 Dec 3;373(23):2247-57. doi: 10.1056/NEJMoa**.
Bentley-Lewis R,Aguilar D, Riddle MC,Claggett B,Diaz R,Dickstein K, Gerstein HC,Johnston P,K?ber LV,Lawson F,Lewis EF,Maggioni AP,McMurray JJ,Ping L,Xu B, Et.al.Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial oflixisenatide versus placebo. Am Heart J. 2015 May;169(5):631-638.e7.


承担科研项目[项目负责人]


2017年，江苏省医学重点学科，江苏省卫生和计划生育委员会，300万
2016年，经皮梗死血管综合血栓清除治疗急性心梗的临床研究，江苏省科技厅社会发展项目（重大项目）BE**，400万
2015年，PAK3在心肌肥大中的作用和机制研究，国家自然基金面上项目，**，73万
2014年，心肌细胞再生的基础和应用研究，南大医学院省分子医学重点实验室，4万
2013年，南京心血管病临床医学中心，南京市卫生和计划生育委员会，1000万
2013年，Cdx2+胎盘干细胞移植治疗急性心肌梗塞的实验研究，国家自然科学基金面上项目，**，70万
2012年，急性心肌梗死的规范化诊治的流程和新技术的建立及应用，江苏省临床医学科技专项，BL**，200万
2011年，转ILK基因治疗终末期心脏病，江苏省卫生厅医学领军人才和领军团队，LJ201153，300万
2011年，转ILK基因治疗终末期心脏病的基础研究，南大中央高校重点项目，，20万
2010年，心肌高表达ILK对心力衰竭心功能的影响及其机制研究，国家自然科学基金面上项目，**，32万
2009年，移植转染ILK基因的干细胞治疗急性心梗疗效和机制研究，省科技厅自然基金，BK**，8万
2008年，糖尿病组织缺血后血管新生障碍的基础和临床研究，科技局国际合作，，10万
2007年，糖尿病血管新生障碍的基础和临床研究，卫生厅兴卫工程，RC**，100万
2006年，心脏干细胞的基础和临床研究，人事厅六大人才高峰项目，5万
2006年，心脏干细胞的基础和临床研究，科技局社会发展，，3万
2004年，糖尿病动脉粥样硬化斑块不稳定性增加的分子机制，省科技厅自然基金，BK**，7.5万
2003年，急性心肌梗塞血管内超声消融的基础和临床研究，卫生局重点项目，ZKX0316，30万

获奖情况

影响心力衰竭发生发展的分子靶点探索和应用基础研究（2019年江苏省科技进步二等奖，排名第一））。
利用系统评价及荟萃分析方法探索并解决心血管介入及药物治疗临床问题（2019年，江苏医学科技一等奖，排名第一）。
左室重构的分子机制和干预靶点的研究（2018年，中华医学科技奖三等奖，排名第一）
左室重构的分子机制和干预靶点的研究（2017年，江苏省医学科技奖一等奖 ，排名第一）。
主动脉内球囊反搏支持下联合血管内超声指导行左主干钙化病变旋磨及药物支架植入术（2017年，江苏省医学新技术一等奖，排名第一）。
进EPC动员治疗心肌梗死的临床新技术应用（2014年，江苏省医学新技术引进一等奖，排名第一）。
糖尿病血管功能障碍的基础及临床研究（2013年，江苏医学科技奖一等奖，排名第一）。
糖尿病血管功能障碍的基础及临床研究（2013年，江苏省科技进步奖三等奖，排名第一）。
糖尿病血管功能障碍的基础及临床研究（2013年，南京市科技进步奖二等奖，排名第一）。