职务：
联系电话：
办公地址： 化学楼E区507室
电子邮箱： wangsz@nju.edu.cn

课题组主页：





个人简介


王少仲，南京大学副教授，博士生导师。1992年9月至2002年6月在南京大学化学化工学院学习；先后获得理学学士（1996）、硕士（1999）和博士（2003）学位。2002年7月任职于南京大学化工学院，2005年6月受聘为副教授。2005年9月至2006年9月赴美国内华达州立大学雷诺分校从事博士后研究。2016年6月受聘为博士生导师。以第一作者和通讯作者身份发表学术论文36篇。先后主持3项国家自然科学基金项目和2项江苏省自然科学基金项目。

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工作经历


2002年9月-2005年5月南京大学化学化工学院讲师
2005年6月-至今南京大学化学化工学院副教授
2005年9月-2006年9月： 美国内华达州立大学里诺分校化学系博士后
2016年6月-至今南京大学化学化工学院博士生导师


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研究方向


1. 炔烃选择性转化



2. 天然生物碱的全合成





学术成果



36. J. Qiao, W. Zhao, Y. Liang*, Z.-J. Yao, S. Wang*,DiastereoselectiveAccess to Tetracyclic Eight-Membered Lactams through a Dearomative Heck Reaction and an Alkylative Ring-Opening Driven by the PhotoexcitedSpiroindolines, Chemistry-A European Journal (2021). DOI 10.1002/chem..


35.Y. Cai, W. Zhao, S. Wang*, Y. Liang, Z.-J. Yao, Access to Functionalized E-Allylsilanes and E-Alkenylsilanes through Visible-Light-Driven Radical Hydrosilylation of Mono- and Disubstituted Allenes, Organic Letters 21(24), 9836-9840 (2019). DOI: 10.1021/acs.orglett.9b03679
34.W.-C. Cui, W. Zhao, M. Gao, W. Liu, S. Wang*, Y. Liang*, Z.-J. Yao*, Diastereoselective Synthesis of Polysubstituted Piperidinesthrough Visible-Light-Driven Silylative Cyclization of Aza-1,6-Dienes: Experimental and DFT Studies, Chemistry-A European Journal 42(72), 16506-16510(2019).DOI: 10.1002/chem.
33.C. Wang, Q. Cui, Z. Zhang, Z.-J. Yao, S. Wang*, Z.-X. Yu*, Divergent Synthesis of Oxa-Cyclic Nitrones through Gold(I)-Catalyzed 1,3-Azaprotio Transfer of Propargylic a-Ketocarboxylate Oximes: Experimental and DFT Studies, Chemistry- A European Journal42(25): 9821-9826 (2019). DOI: 10.1002/chem.
32.J. Zhu, W.-C. Cui, S. Wang*, Z.-J. Yao*, Visible Light-Driven Radical trans-Hydrosilylation of Electron-Neutral and –Rich Alkenes with Tertiary and Secondary Hydrosilanes, The Journal of Organic Chemistry, 83(23), 14600-14609 (2018). DOI: 10.1012/acs.joc.8b02409
31.J. Zhu, W.-C. Cui, S. Wang*, Z.-J. Yao*, Radical Hydrosilylation of Alkynes Catalyzed by Eosin Y and Thiol under Visible Light Irradiation, Organic Letters, 20(11), 3174-3178 (2018). DOI: 10.1021/acs.orglett.8b00909
30.S. Wang*, Alkaloid Synthesis via Gold-Catalyzed Carbon-Carbon Bond Formation Using Enamine-typeNucleophile, Israel Journal of Chemistry, 58(5), 557-567 (2018). DOI: 10.1002/ijch.
29.S. Wang*, Transition metal-catalyzed reactions of propargylic carboxylates via an initial 1,2-acyloxymigration, Tetrahedron Letters, 59(14), 1317-1327 (2018). DOI: 10.1016/j.tetlet.2018.02.054
28.J. Zhu, Y. Yuan, S. Wang*, Z.-J. Yao*, Synthesis of 2,3-Dialkylated Tartaric Acid Esters via Visible LightPhotoredox-Catalyzed Reductive Dimerization of alfa-Ketoesters, ACS Omega, 2(8), 4665-4677 (2017).
27.L. Chang, T. Guo, Z.Wang, S. Wang*, Z.-J. Yao, Azepinoindole Synthesis via a N-Bromosuccinimide-Induced Cycloisomerization of Enaminoester/Enaminone, The Journal of Organic Chemistry82(3): 1567-1574 (2017).DOI:10.1021/acs.joc.6b02760
26.L. Zhang, Y. Wang, Z.-J. Yao, S. Wang*, Z.-X. Yu*, Kinetic or Dynamic Control on aBifurcatingPotentialEnergy Surface? An Experimental and DFT Study of Gold-Catalyzed Ring-Expansion andSpirocyclization of 2-Propargyl-beta-tetahydrocarbolines, Journal of the AmericanSociety137(41): 13290-13300 (2015).DOI:10.1021/jacs.5b05971
25.L. Zhang, L. Chang, H. Hu, H. Wang, Z.-J. Yao, S. Wang*, Azocinoindole Synthesis by a Gold(I)-Catalyzed Ring Expansion of 2-Propargyl-beta-Tetrahydrocarboline, Chemistry- A European Journal20(10): 2925-2932 (2014).DOI:10.1002/chem.
24.H. Yin, N. Shan, S. Wang*, Z.-J. Yao, Total Synthesis of Ascididemin-Type Alkaloids UsingAlkyneBuilding Blocks, The Journal of Organic Chemistry79(20):9748-9753(2014).DOI:10.1021/jo501927e
23.Q. Hou, Z. Zhang, F. Kong, S. Wang*, H. Wang, Z.-J. Yao, Assembly of fused indenes via Au(I)- catalyzed C1–C5 cyclization of enediynes bearing an internal nucleophile, ChemicalCommunication49(7): 695-697 (2013). DOI: 10.1039/C2CC36245G
22.M. Xu, K. Xu, S. Wang*, Z.-J. Yao, Assembly of indolo[1,2-c] quinazolines using ZnBr₂- promoteddomino hydroamination–cyclization, Tetrahedron Letters54(35): 4675-4678(2013).DOI:10.1016/j.tetlet.2013.06.079
21.Z. Zhang, L. Chang, S. Wang*, H. Wang, Z.-J. Yao, Synthesis of 2-Vinyl-2H-benzotriazoles via NIS-Promoted Regio/ Stereoselective Addition of 1H-Benzotriazole to Alkynes, RSC Advance3(40): 18445-18452 (2013).DOI: 10.1039C3RA43075H
20.H. Yin, F. Kong, S. Wang*, Z.-J. Yao, Assembly of Pentacyclic Pyrido[4,3,2-mn]acridin-8-ones via aDomino ReactionInitiated by Au(I)-Catalyzed 6-endo-digCycloisomerization of N-Propargylaminoquinones. Tetrahedron Letters53(52): 7078-7082 (2012).DOI: 10.1039/C3RA43075H
19.N. Fei, H. Yin, S. Wang*, H. Wang, Z.-J. Yao, CuCl₂-Promoted 6-endo-digChlorocyclization and Oxidative Aromatization Cascade: Efficient Construction of 1-Azaanthraquinones from N- Propargylaminoquinones, Organic Letters13(16):4208-4211 (2011).DOI:10.1021/ol201542h
18.M. Xu, Q. Hou, S. Wang*, H. Wang, Z.-J. Yao, Facile Assembly of 11H-Indolo[3,2-c]quinoline by a Two-step Protocol Involving a Regioselective 6-endo-Cyclization Promoted by the HendricksonRreagent,Synthesis(4):626-634 (2011).DOI: 10.1055/s-
17.C. Jiang, M. Xu, S. Wang*, H. Wang, Z.-J. Yao, Azaanthraquinone Assembly from N-Propargylamino-Quinone via a Au(I)-Catalyzed 6-endo-digCycloisomerization, Journal of Organic Chemistry75(12): 4323-4325 (2010).DOI:10.1021/jo**
16.N. Fei, Q. Hou, S. Wang*, H. Wang, Z.-J. Yao, Azaanthraquinone Assembly from N-Propargylaminoquinone via Iodine-Induced 6-endo-digElectrophilic Cyclization, Organic & Biomolecular Chemistry8(18): 4096-4103 (2010).DOI: 10.1039/C004896H
15. S. Wang, G. Zhang, L. Zhang*, Gold-Catalyzed Reaction of Propargylic Carboxylates via an Initial 3,3-Rearrangement, Synlett(5): 692-706 (2010).DOI: 10.1055/s-
14. M. Wu, S. Wang*, An Alternative to Pictet-Gams Reaction Triggered by Hendrickson Reagent: Isoquinolines and beta-Carbolines from Amides, Synthesis(4): 587-592 (2010).DOI: 10.1055/s-
13. C. Jiang, S. Wang*, Gold(III)-Catalyzed 1,4-Nucleophilic Addition: Facile Approach to Prepare 2-Amino-1,4-Naphthalenedione and 6-Amino-5,8-quinolinedione derivatives, Synlett(7): 1099-1102 (2009).DOI: 10.1055/s-
12. S. Li, S. Wang*, FeCl₃-Promoted [3+3] Cycloaddition: Efficient Preparation of 1,2-Dihydro-2-Oxo-3-Pyridinecarboxylate and 1,2-Dihydro-2-Oxo-Pyridinecarboxamide Derivatives, Journal of Heterocyclic Chemistry45(6): 1875-1878 (2008).DOI:10.1002/jhet.
11.S. Wang, L. Zhang*, A Gold-catalyzed Unique Cycloisomerization of 1,5-Enynes: Efficient Formation of 1-Carboxycyclohexa-1,4-dienes and Carboxyarenes, Journal of the American Chemical Society, 128(44): 14274-14275 (2006).DOI:10.1021/ja066220f
10. S. Wang, L. Zhang*, A Highly Efficient Preparative Method of alfa-Ylidene-beta-Diketones via AuIII-Catalyzed Acyl Migration of Propargylic Esters, Journal of the American Chemical Society, 128(26): 8414-8415 (2006).DOI:10.1021/ja062777j
9.L. Zhang*, S. Wang, Efficient Synthesis of Cyclopentenones from Enynyl Acetates via Tandem Au(I)-Catalyzed 3,3-Rearrangement and the Nazarov Reaction, Journal of the American Chemical Society, 128(5): 1442-1443 (2006). DOI:10.1021/ja057327q
8.S. Wang, L. Zhang*, Gold-Catalyzed Efficient Formation of Alkenyl Enol Esters/Carbonates from Trimethylsilylmethyl-Substituted Propargyl Esters/Carbonates, Organic Letters8(20): 4585-4587 (2006).DOI:10.1021/ol**
7.S. Wang*, T. Tan, J. Li, H. Hu, Highly Efficient One-Pot Synthesis of 1,2-Dihydro-2-Oxo-3-Pyridinecarboxylate Derivatives by FeCl₃-Promoted [3+3] Annulation, Synlett(17): 2658-2660 (2005).DOI:10.1055/s-2005-917092
6.S. Wang*, J. Pan, Y. Hu, H. Hu, FeCl₃-Promoted Intramolecular Annulation of d-Keto Nitriles: Facile Approach to Prepare 3-Acetamido-2-pyridone Derivatives, Synthesis(5): 753-756 (2005). DOI: 10.1055/s-2005-861785
5.S. Wang, Y. Dong, X. Wang, X. Hu, J. O. Liu, Y. Hu*, 3-Aryl b-carbolin-1-ones as a new class of potent inhibitors of tumor cell proliferation: synthesis and biological evaluation, Org. Biomol. Chem.3(5), 911-916 (2005). DOI: 10.1039/B412921k
4.S. Wang, L. Cao, H. Shi, Y. Dong, J. Sun, Y. Hu, Preparation of 2-Pyridone-Containing Tricyclic Alkaloid Derivatives as Potential Inhibitors of Tumor Cell Proliferation by Regioselective Intramolecular N- and C- Acylation of 2-Pyridone, Chem. Pharm. Bull.53(1), 67-71 (2005). DOI: 10.1248/cpb.53.67
3.S. Wang, J. Sun, G. Yu, X. Hu, J. O. Liu, Y. Hu*, CuI catalyzed N-arylation of amide as a key step for the preparation of 3-aryl b-carbolin-1-ones, Org. Biomol. Chem.2(11), 1573-1574 (2004). DOI: 10.1039/B406046F
2. G. Yu, S. Wang, K. Wang, Y. Hu*, H. Hu, A Novel Approach to 1,2-Dihydro-2-Oxo-3-Pyridinecarboxylic Ester via Aromatization Induced by Deamidation, Synthesis, (7), 1021-1028 (2004). DOI: 10.1055/s-2004-822325
1.S. Wang, G. Yu, J. Lu, K. Xiao, Y. Hu*, H. Hu, A Regioselective Tandem Reaction between Chalcones and 2-Acetamidoacetamide Promoted by Cs₂CO₃for the Preparation of 3-Unsubstituted 2-Pyridones, Synthesis, (4), 487-490 (2003).


课程名称、上课时间地点


《基础有机化学》（化学专业）

教学大纲、考试要求




教学资源（上课讲义、参考资料等）





课题组风采