沙强/教学科研
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院 系
从事专业学 历
学 位办公室实验室
毕业院校电子邮箱
理学院化学系有机化学
博士研究生博士
理学院 315
理学院 407
南京理工大学
qsha@njau.edu.cn

催化不对称合成、杂环骨架构建、卡宾化学、生物活性分子设计
研究方向











个人简介
2010 年毕业于南京理工大学制药工程专业，获得工学学士学位，随后在南京理工大学硕博连读，师从魏运洋教授，2016 年获得化学工程与技术博士学位。2014.09-2015.09
期间，受留学基金委全额资助赴美国马里兰大学帕克分校及德克萨斯大学圣安东尼奥分校访问交流一年，师从 Michael P. Doyle 教授。2016 年
7月进入南京农业大学理学院工作，目前以第一作者或通讯作者身份在 Chemistry-A European Journal, Organic Letters, Chemical
Communications, The Journal of Organic Chemistry, Advanced Synthesis & Catalysis,
ChemCatChem 等知名期刊发表十多篇 SCI 论文。此外参与了教材《药物合成反应简明教程》5.4 节的编写，发表英文综述一章，申请专利一项。为 Organic Letters, The
Journal of Organic Chemistry, RSC Advances, Letters in Organic Chemistry, Current Organic Chemistry
期刊审稿人。


教学信息

《有机化学》、《化工原理》、《实验化学 I》、《实验化学 II》


科研项目

1、 中央高校基本科研业务费自主创新重点项目(KYZ201751)，2017.01-2019.12，主持，已结题

发表综述或章节

1. Qiang Sha, Yongming Deng, Michael P. Doyle*. The Future of Catalysis by Chiral Lewis
Acids. Topics in Organometallic Chemistry, 2015, doi: 10.1007/3418_2015_141.
2. 参与教材《药物合成反应简明教程》5.4 节（310-335 页）的编写。《药物合成反应简明教程》，2013 年，科学出版社（978-7-03-038164-4），魏运洋、罗军、张树鹏主编。
发表论文

1. De Novo and Divergent Synthesis of Highly Functionalized Furans via Cascade
Reactions of 2-Hydroxy-1,4- diones with Nucleophiles. Haixuan Liu,# Fei Ji,# Yu Chen, Ya
Gao, Junke Wang, Mingzhi Zhang, Fang Liu* and
Qiang Sha.* Chemistry-A European Journal, 2021, 27, 5225-5229.

2. De Novo Synthesis of Benzofurans via

Trifluoroacetic Acid Catalyzed Cyclization/ Oxidative Aromatization Cascade
Reaction of 2-Hydroxy-1,4- diones. Qiang Sha*# and Haixuan Liu#. Organic &. Biomolecular
Chemistry, 2019, 17, 7547-7551.
3. Trifluoroacetic Acid Catalyzed Cascade Reactions of 2,3- Diketoesters with
Cyclohexane-1,3-diones: Strategy Towards 4- Hydroxybenzofuran Derivatives. Qiang
Sha*#, Haixuan Liu#, Yuan Li. Advanced Synthesis & Catalysis, 2019, 361(7), 1627-1631.


4. Synthesis of 1H-Pyrrol-3(2H)-ones via Three-Component Reactions of 2,3- Diketo
Esters, Amines, and Ketones.
Qiang Sha*, Junke Wang, and Michael
P. Doyle. The Journal of Organic Chemistry, 2018, 83(18), 11288-11297.


5. Displacement of Dinitrogen by Oxygen: A Methodology for the
Catalytic Conversion of Diazocarbonyl Compounds to Ketocarbonyl Compounds by
2,6-Dichloropyridine- N-oxide. Yang Yu, Qiang Sha, Hui Cui, Kory S. Chandler, and Michael
P. Doyle*. Organic Letters, 2018, 20 (3), 776-779.

6. Acetic Acid Mediated Sulfonylation of Allenylphosphine Oxides: Divergent Synthesis of
Bifunctionalized 1,3- Butadienes and Allenes. Kai Luo, Ling Zhang, Jing Ma, Qiang Sha,
and Lei Wu*. The Journal of Organic Chemistry, 2017, 82(13), 6978-6985.

7. Asymmetric Synthesis of 1H-Pyrrol- 3(2H)-ones from 2,3-Diketoesters by Combination
of Aldol Condensation with Benzilic Acid Rearrangement.
Qiang Sha, Hadi Arman, Michael P. Doyle*. Chemical Communications, 2016, 52,108-111.
8. Three-Component Cascade Reactions with 2,3-Diketoesters: A Novel Metal- Free Synthesis
of 5-Vinyl-pyrrole and 4-Hydroxy-indole Derivatives. Qiang
Sha, Hadi Arman, Michael P. Doyle*.
Organic Letters, 2015, 17, 3876-3879.

9. Copper(I)-Catalyzed Wittig Olefination Reactions of N-
Tosylhydrazones with Trifluoromethylketones. Qiang Sha, Yunyang
Wei*. ChemCatChem, 2014, 6, 131-134.

10. One-pot Multistep Synthesis of Trisubstituted Alkenes from N-
Tosylhydrazones and Alcohols. Qiang
Sha, Yunyang Wei*. Synthesis, 2014,
46, 2353-2361.


11. Design and Synthesis of 3- Trifluoromethyl-3H-pyrazoles and
Further Investigations of Their Transformation into Novel 1H- Pyrazoles. Q
iang Sha,# Haixuan Liu,# Yunyang Wei*. European Journal of Organic Chemistry, 2014, 34,
7707- 7715. (Qiang Sha and Haixuan Liu contributed equally)

12. An Efficient One-Pot Synthesis of 3, 5- Diaryl-4-bromopyrazoles by 1,3- Dipolar
Cycloaddition of In Situ Generated Diazo Compounds and 1- Bromoalk-1-ynes.
Qiang Sha, Yunyang Wei*. Synthesis, 2013, 45, 413-420. (Highlighted by Organic
Chemistry Portal)

13. Base and Solvent Mediated Decomposition of Tosylhydrazones: Highly
Selective Synthesis of N-Alkyl Substituted Hydrazones,
Dialkylidenehydrazines, and Oximes.
Qiang Sha, Yunyang Wei*.
Tetrahedron, 2013, 69, 3829-3835.

14. One-Pot Synthesis of S-Alkyl Dithiocarbamates via The Reaction of
N-Tosylhydrazones, Carbon Disulfide and Amines. Qiang Sha, Yunyang Wei*. Organic
& Biomolecular Chemistry, 2013, 11, 5615-5620.

15. Capture of In Situ Generated Diazo Compounds or Copper Carbenoids by
Triphenylphosphine: Selective Synthesis of trans-Alkenes and Unsymmetric
Azines via Reaction of Aldehydes with Ketone-Derived N- Tosylhydrazones. Qiang Sha,
Yifei Ling, Wenyong Wang, Yunyang Wei*. Advanced Synthesis & Catalysis, 2013, 355, 2145-2150.

专利

1、“一种多取代 4,5,6,7-四氢苯并呋喃的全新合成方法”，沙强，刘海璇，王俊珂；申请号：201911072910.X；申请日：2019.11.05；公开(公告)号：
CN110713475A；公开(公告)日：2020.01.21。