刘芳／教授



院系：化学系
从事专业：计算化学学历：研究生
职称：教授
电话：18362983986
研究方向：有机反应机理，催化剂设计
性别：女 学位：博士
毕业院校：美国加州大学洛杉矶分校职务：
电子邮箱：acialiu@njau.edu.cn


个人简介
刘芳，教授，博士生导师。2014 年取得博士学位，师从计算有机化学界知名学者、美国科学院院士 K. N. Houk 教授；先后在美国加州大学洛杉矶分校和南京大学进行博士后研究，2018
年作为高层次引进人才加入南京农业大学理学院。主要研究有机反应机理、活性和选择性以及催化剂设计。在 Nature, Acc. Chem. Res., J. Am. Chem. Soc., Angew.
Chem.
Int. Ed.等国际期刊上发表 SCI 论文 20 余篇，其中第一作者文章 7 篇。

工作经历
2018/09-今：南京农业大学，理学院，教授，博士生导师
2016/10-2018/08：南京大学，化学化工学院，博士后
2016/03-2016/09：美国加州大学洛杉矶分校（UCLA），化学与生物化学学院，博士后

教育经历
2009/09-2014/06：美国加州大学洛杉矶分校（UCLA），化学与生物化学学院，博士
2005/09-2009/06：南开大学，化学学院，学士

教学信息
有机化学，物理化学，计算化学课程

科研项目
（2）南京农业大学引进人才科研启动经费，2018/09-2023/09，在研，主持
（1）中国博士后科学基金面上项目，2017/08-2018/08，结题，主持

发表文章
21. Yi-Shuang Wang, Bo Zhang, Jiapeng Zhu, Cheng-Long Yang, Yu Guo, Cheng-Li Liu, Fang Liu, Huiqin
Huang, Suwen Zhao, Yong Liang, Rui-Hua Jiao, Ren-Xiang Tan, and Hui-Ming Ge: “Molecular Basis for
the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis,” J. Am. Chem. Soc. 2018, 140,
10909-10914.



20. Joyann Barber, Michael Yamano, Melissa Ramirez, Evan Darzi, Rachel Knapp, Fang Liu, K.
N. Houk, and Neil Garg: “Diels–Alder Cycloadditions of Strained Azacyclic Allenes,” Nat.
Chem. 2018, 10, 953-960.
19. Huimin Tao?, Fang Liu?, Ruxin Zeng, Zhuzhou Shao, Lufeng Zou, Yang Cao, Jennifer M. Murphy, K.
N. Houk, and Yong Liang: “Origins of Halogen Effects in Bioorthogonal Sydnone Cycloadditions,”
Chem. Commun. 2018, 54, 5082-5085.
18. K. N. Houk and Fang Liu: “John D. Roberts, his beginnings at UCLA, his transformation of
physical organic chemistry, and his impact on science,” J. Phys. Org. Chem. 2018, DOI:
10.1002/poc.3810.
17. Masao Ohashi, Fang Liu, Yang Hai, Mengbin Chen, Man-cheng Tang, Zhongyue Yang,
Michio Sato, Kenji Watanabe, K. N. Houk, and Yi Tang: “SAM-Dependent Enzyme-Catalyzed Pericyclic
Reactions in Natural Product Biosynthesis,” Nature, 2017, 549, 502-506.
16. Fang Liu, Yong Liang, and K. N. Houk: “Bioorthogonal Cycloadditions: Computational
Analysis with the Distortion/Interaction Model, and Prediction of Reactivities,”Acc. Chem. Res.,
2017, 50, 2297-2308.
15. Ilke Ugur, Sesil Agopcan Cinar, Burcu Dedeoglu, Viktorya Aviyente, M.
Frederick Hawthorne, Peng Liu, Fang Liu, K. N. Houk, and Gonzalo Jimenez-Oses:
"1,3-Dipolar Cycloaddition Reactions of Low-Valent Rhodium and Iridium Complexes with
Arylnitrile N- Oxides," J. Org. Chem., 2017, 82, 5096-5101.
14. K. N. Houk and Fang Liu: "Holy Grails for Computational Organic Chemistry and
Bichemistry," Acc. Chem. Res., 2017, 50, 539-543.
13. Abing Duan, Peiyuan Yu, Fang Liu, Huang Qiu, Feng Long Gu, Michael P. Doyle, and K. N. Houk:
"Diazo Esters as Dienophiles in Intramolecular (4 + 2) Cycloadditions: Computational
Explorations of Mechanism," J. Am. Chem. Soc., 2017, 139, 2766-2770.
12. Xia Yu, Fang Liu, Yi Zou, Man-Cheng Tang, Leibniz Hang, K. N. Houk, and Yi
Tang: "Biosynthesis of Strained Piperazine Alkaloids: Uncovering the Concise Pathway of Herquline
A," J. Am. Chem. Soc., 2016, 138, 13529-13532.
11. Yun-Fang Yang, Yong Liang, Fang Liu, and K. N. Houk: "Diels-Alder Reactivities of
Benzene, Pyridine, and Di-, Tri-, and Tetrazines: The Roles of Geometrical Distortions
and Orbital Interactions," J. Am. Chem. Soc., 2016, 138, 1660-1667.
10. David N. Kamber, Yong Liang, Robert J. Blizzard, Fang Liu, Ryan A. Mehl, K. N. Houk, and
Jennifer A. Prescher: "1,2,4-Triazines Are Versatile Bioorthogonal Reagents," J. Am. Chem. Soc.,
2015, 137, 8388-8391.
9. Lisa Tork, Gonzalo Jimenez-Oses, Charles Doubleday, Fang Liu, and K. N.
Houk: "Molecular Dynamics of the Diels-Alder Reactions of Tetrazines with Alkenes
and N2 Extrusions from Adducts," J. Am. Chem. Soc., 2015, 137, 4749-4758.
8. Fang Liu, Yong Liang, and K. N. Houk: "Theoretical Elucidation of the Origins of
Substituent and Strain Effects on the Rates of Diels-Alder Reactions of 1,2,4,5-Tetrazines,"
J. Am. Chem. Soc., 2014, 136, 11483-11493.
7. Fang Liu, Roger C. Helgeson, and K. N. Houk: "Building on Cram's Legacy:
Stimulated Gating in Hemicarcerands," Acc. Chem. Res., 2014, 47, 2168-2176.
6. Denisse de Loera, Fang Liu, K. N. Houk, and Miguel A. Garcia-Garibay: "Aziridine Nitrogen
Inversion by Dynamic NMR: Activation Parameters in a Fused Bicyclic Structure," J. Org.
Chem., 2013, 78, 11623-11636.
5. Fang Liu, Hao Wang, and Kendall N. Houk: "Gating in Host-Guest Chemistry," Curr. Org. Chem.,
2013, 17, 1470-1480.



4. Fang Liu, Robert S. Paton, Seonah Kim, Yong Liang, and K. N. Houk: "Diels-Alder
Reactivities of Strained and Unstrained Cycloalkenes with Normal and
Inverse-Electron- Demand- Dienes: Activation Barriers and Distortion/Interaction Analysis," J.
Am. Chem. Soc., 2013, 135, 15642-15649.
3. Hao Wang, Fang Liu, Roger C. Helgeson, Kendall N. Houk: "Reversible Photochemically
Gated Transformation of a Hermicarcerand to a Carcerand," Angew. Chem. Int. Ed., 2012, 52, 655-659.
2. Yong Liang, Joel L. Mackey, Steven A. Lopez, Fang Liu, and K. N. Houk: "Control
and Design of Mutual Orthogonality in Bioorthogonal Cycloadditions," J. Am. Chem. Soc., 2012, 134,
17904-17907.
1. Fang Liu, Hao Wang, and K. N. Houk: "Gated Container Molecules," Sci. China. Chem.,
2011, 54, 2038-2044.

书籍章节
K. N. Houk, Fang Liu, Yun-Fang Yang, Xin Hong: Applied Theoretical Organic Chemistry, Chapter 13:
The Distortion/Interaction Model for Analysis of Activation Energies of Organic Reactions, pp
371-402. Editor: Dean J. Tantillo. World Scientific, 2018.