姓名：张国敏性别：男
毕业院校：南京农业大学最高学位：博士
办公地址：逸夫楼 1005
办公电话：025-84395294
电子邮箱：zhangguomin@njau.edu.cn
研究方向：动物生殖调控、动物配子生物学和胚胎工程

个人简介：本科（2010 年）和博士研究生（2015 年）毕业于南京农业大学动物科技学院。

科研项目：参与国家自然基金《代谢谱与山羊克隆胚胎及其供体细胞发育潜能相
关性研究》、《山羊早期卵泡和克隆胚胎发育中抗氧化机制的研究》和《长链非编码 RNA 调控山羊体细胞核移植胚胎合子基因激活期重编程的研究》等项目。

荣誉奖项：
发明专利：《一种现代化环保繁殖羊舍》近年代表性论著：
（1）发表论文
[1] Zhang GM, Deng MT, Zhang YL, Fan YX, Wan YJ, Nie HT, Wang ZY, Wang F, Lei ZH. Effect of
PGC-1alpha overexpression or silencing on mitochondrial apoptosis of goat luteinized
granulosa cells [J]. J Bioenerg Biomembr, 2016, 48(5): 493-507
[2] Zhang GM, Wan YJ, Zhang YL, Lan S, Jia RX, Wang ZY, Fan YX, Wang F. Expression of
Mitochondria-Associated Genes (PPARGC1A, NRF-1, BCL-2 and BAX) in Follicular Development
and Atresia of Goat Ovaries [J]. Reprod Domest Anim, 2015, 50(3): 465-473
[3] Zhang GM, Gu CH, Zhang YL, Sun HY, Qian WP, Zhou ZR, Wan YJ, Jia RX,

Wang LZ, Wang F. Age-associated changes in gene expression of goat oocytes [J].
Theriogenology, 2013, 80(4): 328-336
[4] Zhang GM, Sun HY, Dong FL, Wang F, Cao WG. Reprogramming sertoli cells into pluripotent stem
cells [J]. Cell Reprogram, 2014, 16(3): 196-205
[5] Zhang GM, Lan S, Jia RX, Yan GY, Wang LZ, Nie HT, Lei ZH, Wang F.
Age-associated and tissue-specific expression of osteopontin in male Hu sheep reproductive
tract [J]. Tissue Cell, 2016, 48(5): 496-502
[6] Wan YJ, Deng MT, Zhang GM, Ren CF, Zhang H, Zhang YL, Wang LZ, Wang
F. Abnormal expression of DNA methyltransferases and genomic imprinting in cloned goat fibroblasts
[J]. Cell Biol Int, 2016, 40(1): 74-82
[7] Zhou ZR, Jia RX, Zhang GM, Wan YJ, Zhang YL, Fan YX, Wang ZY, Huang P, Wang F. Using
cysteine/cystine to overcome oxidative stress in goat oocytes and embryos cultured in vitro
[J]. Mol Med Rep, 2016, 14(2): 1219-1226
[8] Guo RH, Wan YJ, Xu D, Cui LB, Deng MT, Zhang GM, Jia RX, Zhou WJ, Wang Z, Deng KP, Huang
MR, Wang F, Zhang YL. Generation and evaluation of Myostatin knock-out rabbits and goats
using CRISPR/Cas9 system [J]. Sci Rep, 2016, 6: 29855
[9] Zhang H, Sun LW, Wang ZY, Deng MT, Nie HT, Zhang GM, Ma TW, Wang F. N-carbamylglutamate and
L-arginine improved maternal and placental development in underfed ewes [J]. Reproduction,
2016, 151(6): 623-635
[10] Li PZ, Yan GY, Han L, Pang J, Zhong BS, Zhang GM, Wang F, Zhang YL. Overexpression of
STRA8, BOULE, and DAZL Genes Promotes Goat Bone Marrow-Derived Mesenchymal Stem
Cells In Vitro Transdifferentiation Toward Putative Male Germ Cells [J]. Reprod Sci, 2017,
24(2): 300-312
（2）参编著作
[1] 黄明睿、王锋主编，张国敏副主编，肉羊标准化高效养殖关键技术，江苏凤凰科学技术出版社，2016 年；
[2] 黄明睿、王锋主编，张国敏参编，肉用山羊养殖与疾病防治新技术，中国农业科学技术出版社，2015 年；
[3] 王锋主编，张国敏参编，羊业科学研究进展（2015），中国农业科学技术出版社，2015 年。