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南京农业大学植物保护学院导师教师师资介绍简介-华修德

/2021-03-21



华修德
职 称:副教授,硕士生导师邮 箱:huaxiude@njau.edu.cn联系电话:025-84395479
办公地址:理科楼 B814




研究方向:
农药残留与环境毒理
农药半抗原、抗体(多克隆抗体、单克隆抗体、纳米抗体)、模拟表位、抗免疫复合体多肽的研制,及新颖的农药残留免疫分析方法的开发。

教育经历:
2018.03–2019.03 美国加州大学戴维斯分校农,农业与环境科学学院,访问学者
2007.09–2012.12 南京农业大学植物保护学院,博士
2012.02–2012.08 美国加州大学戴维斯分校农业与环境科学学院,访问学者
2002.09–2006.06 天津农学院园艺系,学士

工作经历:
2015.01-今,南京农业大学植物保护学院,副教授,硕士生导师
2013.02–2014.12,南京农业大学植物保护学院,讲师

执教课程:
农药登记与管理
农药残留与农产品安全植物化学保护实验
农药学
农药加工与管理

承担课题:
1. 国家自然科学基金面上项目,31972311、有机磷类农药噬菌体展示多肽模拟表位在淘选程序中的遗漏机制研究、2020.01-2023.12、58 万元、主持。
2. 国家自然科学基金面上项目,31772194、纳米多肽竞争物与抗体互作的亲和力调控机制研究、2018.01-2021.12、65 万元、主持。
3. 国家重点研发计划子课题,2017YFF0210200、跨境生物产制品和工程生物检验检测及控制技术研究、2017.07-2020.12、50 万元、主持。
4. 国家重点研发计划子课题,2016YFD0200207、化学农药在我国不同种植体系的归趋特征与限量标准、2016.01-2020.12、205 万元、主持。
5. 国家自然科学基金青年项目,31301690、氯噻啉重链抗体亲和性和特异性关键氨基酸残基作用机理的研究、2014.01-2016.12、25 万元、主持。
6. 教育部高等学校博士点基金课题,20130097120006、氯噻啉重链抗体的体外进化及关键氨基酸残基功能的研究、2014.01-2016.12、4 万元、主持。

代表性科研成果:

1. He Chen, Yuan Ding, Qian Yang, Bogdan Barnych, Gualberto González -Sapienza, Bruce D.
Hammock, Minghua Wang, Xiude Hua*. Fluorescent “Turn off-on” Small-Molecule-Monitoring
Nanoplatform Based on Dendrimer-like Peptides as Competitors. ACS Applied Materials &
Interfaces 2019, 11: 33380–33389.
2. Yuan Ding, Xiude Hua*, He Chen, Gualberto Gonzalez-Sapienza, Bogdan Barnych,
Fengquan Liu, Minghua Wang, Bruce D. Hammock. A dual signal immunochromatographic strip
for the detection of imidaclothiz using a recombinant fluorescent-peptide tracer
and gold nanoparticles. Sensors & Actuators: B. Chemical 2019, 297: 126714.
3. He Chen, Qian Yang, Yuan Ding, Natalia Vasylieva, Candace S. Bever, Xiude Hua*,
Minghua Wang, Bruce D. Hammock. Competitive and noncompetitive immunoassays for the
detection of benzothiostrobin using magnetic nanoparticles and fluorescein isothiocyanate-labeled
peptides. Analytical and Bioanalytical Chemistry 2019, 411: 527–535.
4. Yuan Ding, Xiude Hua*, Mei Du, Qian Yang, Lina Hou, Limin Wang, Fengquan Liu, Gualberto
Gonzalez-Sapienza, Minghua Wang. Recombinant, Fluorescent, Peptidomimetic Tracer for
Immunodetection of Imidaclothiz. Analytical Chemistry 2018, 90: 13996–14002.
5. Yuan Ding, Xiude Hua*, He Chen, Fengquan Liu, Gualberto González -Sapien, Minghua
Wang. Recombinant peptidomimetic-nano luciferase tracers for sensitive single-step immunodetection
of small molecules. Analytical Chemistry 2018, 90: 2230–2237.
6. Xiude Hua, Yuan Ding, Jiachuan Yang, Ming Ma, Haiyan Shi, Minghua Wang*. Direct competitive
fluoroimmunoassays for detection of imidaclothiz in environmental and
agricultural samples using quantum dots and europium as labels. Science of the Total
Environment 2017, 583: 222–227.
7. Hongjie You1, Xiude Hua1, *, Lu Feng, Nana Sun, Qi Rui, Limin Wang, Minghua Wang.
Competitive immunoassay for imidaclothiz using upconversion nanoparticles and gold
nanoparticles as labels. Microchim Acta 2017, 184: 1085–1092. (co-first author)

8. Yuan Ding, Xiude Hua*, Nana Sun, Jiachuan Yang, Jiaqi Deng, Haiyan Shi, Minghua
Wang. Development of a phage chemiluminescent enzyme immunoassay with high sensitivity for the
determination of imidaclothiz in agricultural and environmental samples. Science of the Total
Environment 2017, 609: 854–860.
9. Xiude Hua, Hongjie You, Peiwen Luo, Zhexuan Tao, He Chen, Fengquan Liu, Minghua
Wang. Upconversion fluorescence immunoassay for imidaclothiz by magnetic nanoparticle
separation. Analytical and Bioanalytical Chemistry 2017, 409: 6885–6892.
10. Xiude Hua, Liangliang Zhou, Lu Feng, Yuan Ding, Haiyan Shi, Limin Wang, Shirley J.
Gee, Bruce D. Hammock, Minghua Wang. Competitive and noncompetitive phage
immunoassays for the determination of benzothiostrobin. Analytica Chimica Acta 2015, 890:
150–156.
11. Xiude Hua, Xiaofeng Liu, Wei Yin, Yazhong Xia, Qiujun Zhou,Yiwen Lu,Wei Li, Haiyan Shi,
Fengquan Liu, Minghua Wang. A sensitive monoclonal antibody-based enzyme-linked
immunosorbent assay for the detection of bifenthrin in a chemical soil barrier. Science
of the Total Environment 2015, 502: 246–251.
12. Xiude Hua, Wei Yin, Haiyan Shi, Ming Li, Yanru Wang, Hong Wang, Yonghao Ye, Hee Joo Kim,
Shirley J. Gee, Minghua Wang, Fengquan Liu, Bruce D. Hammock. Development of phage
immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in
agroproducts. Analytical Chemistry 2014, 86: 8441-8447.
13. Xiude Hua, Guoliang Qian, Jifei Yang, Baishi Hu, Jiaqin Fan, Na Qin, Gang Li, Yuyan Wang,
Fengquan Liu. Development of an immunochromatographic assay for the rapid detection of
chlorpyrifos-methyl in water samples. Biosensors and Bioelectronics 2010, 26: 189–194.


社会服务工作:
中国植物保护学会青年委员会委员

Anal.Chem.; Biosens. Bioelectro.; J Hazard Mater.; Anal. Chim. Acta; Scientific Reports; J. Agric.
Food Chem.; Food Chem.等多种 SCI 刊物的审稿人

荣誉奖励:
江苏省高校“青蓝工程”优秀青年骨干教师,2016南京农业大学钟山学术新秀,2019
华修德(2/11),农产品中农药残留快速免疫检测技术与产品,江苏省科学技术奖,一等奖,2017(2017-1-24-R2)
华修德(7/12),农产品中农药与重金属快速免疫检测技术创建及应用,神农中华农业科技奖,一等奖,2017(KJ2017-D1-025-07)
华修德(2/11),农产品与环境中农药、重金属快速检测技术与产品,中国植物保护学会,科学技术奖,一等奖,2016(2016-YJ-1-02-R02)
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