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南京农业大学动物科技学院研究生导师简介-李 娟

南京农业大学 免费考研网/2013-12-29

姓  名:李娟性  别:职  称:副教授最高学历:博士毕业院校:丹麦AarhusUniversity专业领域:动物繁殖与遗传育种联系方式:E-mail:juanli@njau.edu.cnTel:研究方向:动物遗传与繁殖,细胞重编程,胚胎,克隆转基因动物参加学术团体及任职情况:国际胚胎移植学会会员(IETS,InternationalEmbryoTransferSociety),欧洲胚胎移植协会会员(AETE:EuropeanEmbryoTransferAssociation),中国畜牧兽医学会会员。曾应邀为《CloningandStemCells》、《LifeScience》、《VeterinaryJournal》、《MolecularBiologyReports》等国际刊物审稿。承担项目:教育部博士点基金(新教师类),2014-2016年,主持江苏省青年基金,“脂滴含量对胚胎发育的影响”,2013年-2016年,主持中国中央高校基础科研业务经费:“猪克隆胚胎的5-羟甲基胞嘧啶(5-hmC)表观分析”,2011年5月–2014年4月,主持
留学回国人员科技活动项目择优资助项目:猪体细胞两种克隆胚胎的甲基化研究,2012年9月,主持国家自然基金面上项目:let-7家族miRNA调控猪卵泡闭锁的分子机制研究,2012年–2015年,参与
南京农业大学人才引进经费,2011年11月,主持
丹麦FTP博士后项目:”Reductionofdevelopmentalproblemsinporcineembryosandfetusescausedbydifferentin-vitromanipulationprocedures”。2009年9月-2012年8月,项目执行论文论著:LiJ,LiR,VillemoesK,LiuY,PurupS,CallesenH.(2013).Developmentalpotentialandkineticsofpigembryoswithdifferentcytoplasmicvolume.Zygote,Accepted.LiJ,LiR,LiuY,VillemoesK,PurupS,CallesenH.(2013).DevelopmentalKineticsofpigembryosbyparthenogeneticactivationorbyhandmadecloning.ReprodDomesticAnim,48(5):866-73.JuanLi,RongLi,YingLiu,StigPurup,HenrikCallesen.(2012).NuclearTransferefficiencyinpigusingoocytesfromprepubertalgiltsvssows.Zygote.Accepted.
Al-MashhadiRH,S?rensenCB,KraghPM,ChristoffersenC,MortensenMB,TolbodLP,ThimT,DuYT,LiJ,LiuY,MoldtB,SchmidtM,VajtaG,LarsenT,PurupS,BolundL,NielsenLB,CallesenH,FalkE,MikkelsenJG,BentzonJF.(2012)FamilialhypercholesterolemiaandatherosclerosisinclonedminipigscreatedbyDNAtranspositionofahumanPCSK9gain-of-functionmutant.ScienceTranslationalMedicine.(accepted).
StaunstrupNH,MadsenJ,PrimoMN,LiJ,LiuY,KraghPM,LiR,SchmidtM,PurupS,Dagn?s-HansenF,SvenssonL,PetersenTK,CallesenH,BolundL,MikkelsenJG.(2012).DevelopmentofTransgenicClonedPigModelsofSkinInflammationbyDNATransposon-DirectedEctopicExpressionofHumanβ1andα2Integrin.PLoSOne.7(5):e36658.Epub2012May10.
DeshmukhRS,OstrupO,StrejcekF,VejlstedM,Lucas-HahnA,PetersenB,LiJ,CallesenH,NiemannH,HyttelP.(2012).EarlyAberrationsinChromatinDynamicsinEmbryosProducedUnderInVitroConditions.CellReprogram.14(3):225-34.
LiuY,OstrupO,LiJ,VajtaG,LinL,KraghPM,PurupS,HyttelP,CallesenH.(2012).Increasedblastocystformationofclonedporcineembryosproducedwithdonorcellspre-treatedwithXenopuseggextractand/ordigitonin.Zygote.20(1):61-6.
LiR,LiJ,LiuY,KraghPM,HyttelP,SchmidtM,CallesenH.(2012).Optimaldevelopmentalstageforvitrificationofparthenogeneticallyactivatedporcineembryos.Cryobiology.64(1):60-4.
LiuY,?strupO,LiJ,VajtaG,KraghPM,PurupS,CallesenH.(2011).CellcolonyformationinducedbyXenopuseggextractasamarkerforimprovementofclonedblastocystformationinthepig.CellReprogram.13(6):521-6.
RS.Deshmukh,O.Ostrup,E.Ostrup,M.Vejlsted,H.Niemann,A.Lucas-Hahn,B.Petersen,J.Li,H.CallesenandP.Hyttel.(2011).DNAmethylationinporcinepreimplantationembryosdevelopedin-vivoandproducedbyin-vitrofertilization,parthenogeneticactivationandsomaticcellnucleartransfer.Epigenetics,6(2):177-87.
SchmidtM,WinterKD,DantzerV,LiJ,KraghPM,DuY,LinL,LiuY,VajtaG,SangildPT,CallesenH,AgerholmJS.(2011).Maternalendometrialoedemamayincreaseperinatalmortalityofclonedandtransgenicpiglets.ReprodFertilDev.23(5):645-53.
JakobsenJE,LiJ,MoldtB,KraghPM,CallesenH,HertzJM,BolundL,J?rgensenAL,MikkelsenJGandNielsenAL(2011).Establishmentofaporcinefibroblastderivedcelllineforlocus-directedtransgeneexpressionincellculturesandblastocysts.MolecularBiotechnologyreports.38(1):151-61.
JakobsenJ.E.,LiJ.,KraghP.M.,MoldtB.,LinL.,LiuY.,SchmidtM.,WintherK.D.,SchythB.D.,HolmI.E.,VajtaG.,BolundL.,CallesenH.,J?rgensenA.L.,NielsenA.L.,andMikkelsenJ.G.(2011).PigtransgenesisbysleepingbeautyDNAtransposition.TransgenicResearch,20(3):533-45.
LuoY,LiJ,LiuY,LinL,DuY,LiS,YangH,VajtaG,CallesenH,BolundL,S?rensenCB.(2011),HighefficiencyofBRCA1knockoutusingrAAV-mediatedgenetargeting:developingapigmodelforbreastcancer.TransgenicRes.TransgenicRes.20(5):975-88.
SchmidtM,KraghPM,LiJ,DuY,LinL,LiuY,VajtaG,CallesenH.(2010).Pregnanciesandpigletsfromlargewhitesowrecipientsaftertwotransfermethodsofclonedandtransgenicembryosofdifferentpigbreeds.Theriogenology,74(7),1233-40.
LiJ,SvarcovaO,VillemoesK,KraghPM,SchmidtM,B?ghIB,ZhangYH,Duy,LinL,PurupS,XueQZH,BolundL,YangHM,Maddox-HyttelP,VajtaG.(2009).HighinvitrodevelopmentaftersomaticcellnucleartransferandtrichostatinAtreatmentofreconstructedporcineembryos.Theriogenology,68(8):1104-10.
LiJ,VillemoesK,ZhangYH,DuY,KraghP,PurupS,XueQZH,PedersenAM,J?gensenAL,JakobsenJE,BolundL,YangHM,VajtaG.(2009).Efficiencyoftwoenucleationmethodsconnectedtohandmadecloningtoproducetransgenicporcineembryos.ReproductioninDomesticAnimals.44(1):122-7.
J.Li,G.VajtaandH.Callesen.(2009).ComparisonofcellnumbersofZona-IntactandZona-Freeparthenogenticallyactivatedporcineembryosculturedinvitro.Reproduction,FertilityandDevelopment,Vol22(1):234.(Abstract)
KraghPM,NielsenAL,LiJ,DuY,LinL,SchmidtM,B?ghIB,HolmIE,JakobsenJE,JohansenMG,PurupS,BolundL,VajtaG,J?rgensenAL.(2009).HemizygousminipugsproducedbyrandomgeneinsertionandhandmadecloningexpresstheAlzheimer’sdisease-causingdominantmutationAPPsw.TransgenicResearch.18(4):545-58.
LinL,DuY,LiuY,KraghP,LiJ,PurupS,KuwayamaM,ZhangX,YangH.M,BolundLandVajtaG.(2009).ElevatedNaClconcentrationimprovescryotoleranceanddevelopmentalcompetenceofporcineoocytes.ReproductionBiomedicineOnline:18(3):360-6.
LiuY,DuY,LinL,LiJ,KraghP,KuwayamaM,BolundL,YangH.M,andVajtaG.(2008).Comparisonofefficiencyofopenpulledstraw(OPS)andCryotopvitrificationforcryopreservationofinvitromaturedpigoocytes.CryoLetters:29(4):315-20.
DuY,LinL,SchmidtM,B?ghIB,KraghP,S?rensenCB,LiJ,PurupS,PribenszkyC,Moln?rM,KuwayamaM,ZhangX,YangH.M,BolundL,VajtaG.(2008).Highhydrostaticpressuretreatmentofporcineoocytesbeforehandmadecloningimprovesdevelopmentalcompetenceandcryosurvival.CloningandStemCells,10(3):325-30.
J.Li,Y.Du,P.M.Kragh,S.Purup,K.Villemoes,A.M.Pedersen,A.L.J?rgensen,L.Bolund,H.M.YangandG.Vajta.(2007).DevelopmentofpigembryosclonedfromdonorcellstreatedwithtrichostatinA.Reproduction,FertilityandDevelopment.Vol20(1):101.(Abstract)
DuY,LiJ,KraghP,ZhangY,SchmidtM,B?ghI.B,ZhangX,PurupS,KuwayamaM,J?rgensenA.L,PedersenA,VillemoesK,YangH.M,BolundLandVajtaG.(2007).Pigletsbornfromvitrifiedclonedblastocystsproducedwithasimplifiedmethodofdelipationandnucleartransfer.CloningandStemCells:9(4):469-76.
ZhangY,LiJ,VillemoesK,PedersenA,PurupS,VajtaG.(2007).Anepigeneticmodifierresultsinimprovedinvitroblastocystproductionaftersomaticcellnucleartransfer.(2007).CloningandStemCells:9(3):357-63.
DuY,KraghP,ZhangY.H,LiJ,SchmidtM,B?ghI.B,ZhangX,PurupS,J?rgensenA.L,PedersenA,VillemoesK,YangH.M,BolundLandVajtaG.(2007).Pigletsbornfromhandmadecloning,aninnovativecloningmethodwithoutmicromanipulation.Theriogenology,68(8):1104-10.
DuY,ZhangY.H,LiJ,KraghP,KuwayamaM,IedaS,ZhangX,SchmidtM,B?ghI.B,PurupS,PedersenA,VilemoesK,YangH.M,BolundLandVajtaG.(2007).Simplifiedcryopreservationofporcineclonedblastocysts.Cryobiology:54(2):181-7.
LiJ,DuY.,ZhangYH.,KraghPM.,PurupS.,BolundL.,YangH.,XueQZH.,VajtaG.(2006).Chemicallyassistedhandmadeenucleationofporcineoocytes,CloningandStemCells,8(4):241-50.
J.Li,Y.H.Zhang,Y.Du,P.M.Kragh,S.Purup,A.M.Pedersen,K.Villemoes,A.L.J?rgensen,L.Boludn,Q.Z.Xue,H.M.Yang,G.Vajta.(2006).Efficiencyoftwoenucleationmethodsfortheproductionoftransgenicpigembryosbyhandmadecloning.Reproduction,FertilityandDevelopment.Vol19(1):148.(Abstract)
JLi,Y.Du,Y.H.Zhang,P.M.Kragh,L.Bolund,H.Yang,Q.ZXueandG.Vajta.(2006).Efficiencyofchemicallyassistedhandmadeenucleationofporcineooctyes.ReproductioninDomesticAnimals.Vol41(4):340.(Abstract)基因表达序列标签(EST)数据分析手册,胡松年主编,浙江大学出版社,2005年,第六章,EST功能分类与代谢途径分析(李娟,刘贵明,薛庆中),p128-149。奖励及荣誉:不详
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