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南京师范大学生命科学学院研究生导师简介-余书勤

南京师范大学 免费考研网/2013-12-13


 男,汉族,1962年2月生。籍贯湖北。医学硕士、副教授。生理学硕士研究生导师;微生物与生化制药硕士研究生导师。研究方向:抗癌药物多药耐药(Multidrugresistance,MDR)逆转和药代动力学(Pharmacokinetics,PK)研究,新型纳米递药系统(Nano-drugdeliverysystem,Nano-DDS)的研发与生物效应机理研究;外来化合物的毒代动力学(Toxicokinetics,TK)及毒理学研究。近年来以通讯作者共发表23篇论著,7篇SCI中3篇1区、2篇2区。参加国际会议两次,发表7篇会议论著。以非通讯作者发表6篇SCI,其中2篇2区,1篇EI。国际专利公开(PCT)1项,申请2项。国内专利公开6项。参与撰写国际专著一部。近4年毕业研究生中获得国家奖学金1人,校级优秀研究生3人。多人在制药业跨国公司从事研发工作。通讯地址:南京师范大学生科院47号信箱。Eamil:yushuqin@njnu.edu.cn。Tel:13805178158代表性论著(*为通讯作者):1.YingWang,MiaoGuo,YuLu,Li-YingDing,Wen-TingRon,Ya-QingLiu,Fei-FeiSongandShu-QinYu*.Alpha-tocopherylpolyethyleneglycolsuccinate-emulsifiedpoly(lactic-co-glycolicacid)nanoparticlesforreversalofmultidrugresistanceinvitro.Nanotechnology23(2012)495103(14pp)SCI,I区,IF3.979,TOP2.ChenCheng,XieXiaoXia,ZhouQian,ZhangFengYi,WangQiaoLin,LiuYaQing,ZouYiNa,TaoQing,JiXueMei,YuShuQin*.EGF-functionalizedsingle-walledcarbonnanotubesfortargetingdeliveryofetoposide.Nanotechnology2012,23;04510412ppSCI,I区,IF3.979,TOP3.XieXiaoXia,TaoQing,ZouYina,ZhangFengYi,GuoMiao,WangYing,WangHui,ZhouQian,YuShuQin*.PLGAnanoparticlesimprovetheoralbioavailabilityofcurcumininrats:characterizationsandmechanisms.JournalofAgriculturalandFoodChemistry2011,59(17),9280–9289SCI,I区,IF2.816,TOP4.WangHui,XieXiaoXia,ZhangFengYi,ZhouQian,TaoQing,ZouYina,ChenCheng,YuShuQin*.EvaluationofcholesteroldepletionasamarkerofnephrotoxicityinvitroforNovelβ-CyclodextrinDerivatives.FoodandChemicalToxicology2011,49(6):1387-1393SCI,II区,IF2.9995.XuQian,WangMin,YuShuQin*,TaoQing,TangMeng.Traceanalysisofdiethylstilbestrol,dienestrolandhexestrolinenvironmentalwaterbyNylon6nanofibersmat-basedsolid-phaseextractioncoupledwithliquidchromatography-massspectrometry.Analyst2011,136(23):5030-5037SCI,II区,IF4.236.HuangXingXing,ZhouChengLiang,WangHui,ChenCheng,YuShuQin*,XuQian,ZhuYinYan,RenYong.Pharmacokinetics,efficacy,andsafetyevaluationofdocetaxel/hydroxypropyl-sulfobutyl-beta-cyclodextrininclusioncomplex.AAPSPharmSciTech2011,12(2):665-672SCIE,IV区,IF1.4327XuGuangLin,YaoLin,GongZuNan,ZhangShunQuan,YuShuQin*:Attenuationofacutelunginjuryinmicebyoxymatrineisassociatedwithinhibitionofphosphorylatedp38mitogen-activatedproteinkinase.JEthnopharmacol2005,98(1,2):177183SCI,III区,IF3.0148.TingTingYan,QingLi,HuiTingZhou,YueTaoZhao,ShuQinYu,GuangLinXu,ZhiMinYin,ZhongJunLi*,ZhiHuiZhao*(2012)Gu-4SuppressesAffinityandAvidityModulationofCD11bandImprovestheOutcomeofMicewithEndotoxemiaandSepsis.PLoSONE7(2):e30110.SCIE,II区,IF4.0239.ZengJian,RenYong*,ZhouChengLiang,YuShuQin,ChenWen-Hua*.Preparationandphysicochemicalcharacteristicsofthecomplexofedaravonewithhydroxypropyl-β-cyclodextrin.CarbohydratePolymers2011,83(3):1101-1105SCI,III区IF3.4,10.ChenD,WangQ,JinJ,WuP,WangHui,YuShuQin,ZhangH,CaiC.Low-potentialdetectionofendogenousandphysiologicaluricacidatUricasethionineaingle-walledcarbonnanotubemodifiedelectrodes.Anal.Chem.2010,82(6):2448-2455SCI,II区IF5.90,11.ZhuYinyan,AnXueqin,LiShuping,YuShuQin.Nanoencapsulationofβ-CypermethrinbyComplexCoacervationinaMicroemulsion.JSurfactantsDetergents2009,12(4):305SCI,IV区12.XuGL,QianZY,YuShuQin,GongZN,ShenXC.Evidenceofcrocinagainstendothelialinjuryinducedbyhydrogenperoxideinvitro.JAsianNatProdRes2006,8(1-2):7985SCI,IF0.706,IV区13.ZhangNiping,YuShuqin,WangHui,ShenYanyan,XuShi,ZhangLing,XuQian.Methodforquantificationofprazosinindogplasmaanditsapplicationtopharmacokineticstudy.JournalofSoutheastUniversity(EnglishEdition)2011,27,(2):217-221国际会议论著1.QingTao,QianZhou,HuiWang,XiaoxiaXie,YinaZou,FengyiZhang,ChenglianZhou,YuShuQin*.MβCDimprovesoralbioavailabilityofedaravonebyinhibitingp-glycoproteinofintestinalepitheliumcell.3rdChina-EuropeSymposiumonBiomaterialsinRegenerativeMedicine(CESB2011)2.FengyiZhang,HuiWang,XiaoxiaXie,QingTao,QianZhou,ChengChen,YuShuQin*.EvaluationofSPE-SBE-β-CDonnephrocytetoxicityandhemolysisinvitro.3rdChina-EuropeSymposiumonBiomaterialsinRegenerativeMedicine(CESB2011)(April4-8,2011,Nanjing,China)3.XiaoxiaXie,FengyiZhang,QingTao,YinaZou,HuiWang,ChengChen,ChenglianZhou,QianZhou,YuShuQin*.PreparationandcharacterizationofcurcuminPLGA-nanoparticleswithimprovedoralbioavilability.3rdChina-EuropeSymposiumonBiomaterialsinRegenerativeMedicine(CESB2011)(April4-8,2011,Nanjing,China)4.YinaZou,QingTao,FengyiZhang,XiaoxiaXie,QianZhou,ZhihuiZhao,ZhongJunLi,YuShuQin*.DeterminationandpharmacokineticsofFITC-labeledGU-4inratsbymicroplatfluorescenceassay.3rdChina-EuropeSymposiumonBiomaterialsinRegenerativeMedicine(CESB2011)(April4-8,2011,Nanjing,China)5.QianZhou,ChengChen,FenyiZhang,HuiWang,QinTao,XiaoxiaXie,YinaZou,ChenglianZhou,YuShuQin*.CNTs/etoposidebasedRGD/P-GPinhibitortoactivetargetingandinhibitedrugeffluxinMDRtumorcells.3rdChina-EuropeSymposiumonBiomaterialsinRegenerativeMedicine(CESB2011)(April4-8,2011,Nanjing,China)6.YingWang,MiaoGuo,YuLu,LiYingDing,ShuQinYu*.PLGANanoparticlesContainingSN-38forReversingMultipleDrugResistanceofA549/DDPCells.2ndSymposiumonInnovativePolymersforControlledDelivery(SIPCD2012,September11-14,Suzhou·China)7.MiaoGuo,YingWang,WentingRong,LiyingDing,ShuqinYu*Chitosan-modifiedPLGANanoparticlesasDrugDeliveryCarrierforModulatingP-glycoproteinofEnterocytes.2ndSymposiumonInnovativePolymersforControlledDelivery(SIPCD2012,September11-14,Suzhou·China)国际专利1.USAPatentNO.:8,278,437B2:RenYong,MaXueqin,YuShuQin,SunXiaodong:Hydroxypropyl-Sulfobutyl-Beta-Cyclodextrin,thePreparationMethod,theAnalyticalMethod,andthePharmacuticalApplicationThereof.公开日期20121002[国际专利PCT]2.USAPatentapplicationnumber:20100041625YongRen,YuShuQin,JianfengGao,LingWuPharmaceuticalcompositioncomprisingcyclodextrinpaclitaxelinclusionandpreparationmethodthereof3.USAPatentapplicationnumber:20100048685RenYong,GaoJianfeng,YuShuQin,WuLing:Pharmaceuticalcompositioncontainingdocetaxel-cyclodextrininclusioncomplexanditspreparingprocess
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