任乾南京市栖霞区文苑路1号南京师范大学生命科学学院手机:13605157338或者18921448152E-mail:renqian0402@126.com·教育背景2005.9-2010.7山东大学，985+211院校生命学院（硕博连读）动物生化与分子生物学方向，研究课题：无脊椎动物先天免疫，于2010年7月获得博士学位，在读期间获得过光华奖学金，社会实践奖学金等荣誉2001.09-2005.06陕西师范大学211院校生命学院生物科学理学学士多次获得二等，三等奖学金2005年被评为校级优秀毕业生工作简历2010.07-2012.02江苏大学生命科学研究院担任助理研究员职位，从事水生生物天然免疫研究2012.03-至今南京师范大学生命科学学院副教授从事水生生物病害及其免疫防御研究另外，博士学位论文正在申报山东省优秀博士论文目前主要研究领域目前主要从事的研究领域，是软体动物三角帆蚌和节肢动物甲壳纲罗氏沼虾和克氏原鳌虾和昆虫纲家蝇的先天免疫系统。三角帆蚌是一种重要的产珍珠淡水河蚌，近年来，三角帆蚌的养殖受到细菌和瘟病病毒的影响，给三角帆蚌的养殖带来了严重的损失，因此，对三角帆蚌先天免疫系统的研究，可以更加清楚的了解三角帆蚌的免疫防御机制，从未为三角帆蚌疾病的治疗和防御提供理论基础。另外，罗氏沼虾和龙虾的养殖近年来饱受病毒的困扰，研究罗氏沼虾的抗病毒机制，具有一定的理论价值和现实意义。家蝇的生长环境中充斥着各种各样的微生物，研究家蝇的免疫防御，具有重要的意义。例外，通过生物信息学和比较基因组学的方法，研究节肢动物，软体动物先天免疫防御的差异。在研项目1.罗氏沼虾GTPases多样性及其在先天免疫中的功能研究。国家基金青年项目23万主持2.苏南五市静脉吸毒人群在全国HCV和HIV时空传播动力学中的作用研究。并列主持人3.三角帆蚌防御素在抗艾滋病中的功能MR&NPC2010001陕西师范大学教育部“药用植物资源与天然药物化学”重点实验室开放课题主持2万4.三角帆蚌防御素基因多样性及其抗HIV研究10JDG122江苏大学高级专业人才科研启动基金主持5万5.Phospholamban蛋白在气道平滑肌细胞收缩中的功能重庆大学生物流变科学与技术教育部重点实验室访问学者基金主持5万6.C1Q基因在三角帆蚌先天免疫中的功能研究江苏省博士后基金B类主持3.5万7.罗氏沼虾Toll样受体基因克隆及其性质研究中国博士后基金二等资助主持3万8.罗氏沼虾GTPases在先天免疫中功能南京师范大学高层次人才启动经费主持6万其它参与的项目1.对虾转录激活反应RNA结合蛋白与真核翻译起始因子6在对虾抗病毒防御中的作用国家基金面上项目30972236/C190101参与2.对虾免疫相关基因在生殖系统中的表达与功能分析国家基金青年基金30800839/C190101第三3.对虾C-型凝集素及其在先天免疫中的功能分析。30770282国家基金面上项目第二位4.5.以下为发表文章，计28篇SCI以第一作者发表19篇，其中影响因子3以上的文章11篇,2-3之间的4篇，1-2之间的四篇，总影响因子接近50，发表的文章大多是鱼类贝类免疫学和比较与发育免疫学，另外，还在比较生化生理B和C，遗传学报，昆虫生化生理，分子生物学报告等杂志发表文章。1.RenQ,ZhouJ,JiaYP,WangXW,ZhaoXF,WangJX.CloningandcharacterizationofRapGTPasefromtheChinesewhiteshrimpFenneropenaeuschinensis.DevCompImmunol2012,36:247-52.2,RenQ,ZhouJ,ZhaoXF,WangJX.PotentialroleofsinglehotdogfoldthioesteraseintheantiviralresponseofFenneropenaeuschinensis.FishShellfishImmunol2011,30:1192-6.3，RenQ,ZhaoXF,WangJX.Identificationofthreedifferenttypesofserineproteases(oneSPandtwoSPHs)inChinesewhiteshrimp.FishShellfishImmunol2011,30:456-66.4,RenQ,ZhouJ,SunSS,KangCJ,ZhaoXF,WangJX.Molecularcloningandexpressionpatternanalysisoftwonoveldisulfideisomerasesinshrimp.CompBiochemPhysiolCToxicolPharmacol2011,153:301-9.5.RenQ,ZhouJ,ZhaoXF,WangJX.MolecularcloningandcharacterizationofareceptorforactivatedproteinkinaseC1(RACK1)fromChinesewhiteshrimp,Fenneropenaeuschinensis.DevCompImmunol2011,35:629-34.6.RenQ,ZhangW,ZhaoXF,WangJX.GeneCloningandExpressionAnalysisofUbiquitinDerivedFromMuscadomestica.ArchInsectBiochemPhysiol2008,68:89–99.7.RenQ,ZhaoX,WangJ.Molecularcharacterizationandexpressionanalysisofachicken-typelysozymegenefromhousefly(Muscadomestica).J.Genet.Genomics2009,36:7-16.8.RenQ,SunRR,ZhaoXF,WangJX.Aselenium-dependentglutathioneperoxidase(Se-GPx)andtwoglutathioneS-transferases(GSTs)fromChineseshrimp(Fenneropenaeuschinensis).CompBiochemPhysiolCToxicolPharmacol2009,149:613–623.9.RenQ,XuZL,WangXW,ZhaoXF,WangJX.ClipdomainserineproteaseanditshomologrespondtoVibriochallengeinChinesewhiteshrimp,Fenneropenaeuschinensis.FishShellfishImmunol2009,26:787-798.10.RenQ,ZhangRR,ZhaoXF,WangJX.AthioredoxinresponsetotheWSSVchallengeontheChinesewhiteshrimp,Fenneropenaeuschinensis.CompBiochemPhysiolCToxicolPharmacol2010,151:92-98.11.RenQ,DuZQ,ZhaoXF,WangJX.AnAcyl-CoA-bindingprotein(FcACBP)andafattyacidbindingprotein(FcFABP)responsetomicrobeinfectioninChinesewhiteshrimp,Fenneropenaeuschinensis.FishShellfishImmunol2009,27:739-747.12.RenQ,ZhangXW,SunYD,SunSS,ZhaoXF,WangJX.TwoCysteineProteinasesrespondtoBacterialandWSSVChallengeinChinesewhiteshrimpFenneropenaeuschinensis.FishShellfishImmunol,201029:551-556.13.ShiXZ,RenQ,ZhaoXF,WangJX.Expressionoffourtrypsin-likeserineproteasesfromtheChineseshrimp,Fenneropenaeuschinensis,asregulatedbypathogenicinfection.CompBiochemPhysiolBBiochemMolBiol2009,153:54–60.(下划线为并列第一作者)。14.DuZQ,RenQ,ZhaoXF,WangJX.AdoubleWAPdomain(DWD)-containingproteinwithproteinaseinhibitoryactivityinChinesewhiteshrimp,Fenneropenaeuschinensis.CompBiochemPhysiolBBiochemMolBiol2009,154:203-210.15.WangJX,ZhaoXF,LiangYL,LiL,ZhangW,RenQ,WangLC,WangLY.Molecularcharacterizationandexpressionoftheantimicrobialpeptidedefensinfromthehousefly(Muscadomestica).Cell.Mol.LifeSci.2006,63:3072–3082.16.RenQ,LiM,ZhangCY,ChenKP.Sixdefensinsfromthetriangle-shellpearlmusselHyriopsiscumingii.FishShellfishImmunol2011,31:1232-8.17.RenQ,DuZQ,LiM,ZhangCY,LuJ,XuQG,ChenKP.Cloningandexpressionanalysisofananti-lipopolysaccharidefactorfromgiantfreshwaterprawn,Macrobrachiumrosenbergii.2012,39:7673-80.18.RenQ,LiM,DuJ,ZhangCY,WangW.Immuneresponseoffourdual-CRDC-typelectinstomicrobialchallengesingiantfreshwaterprawnMacrobrachiumrosenbergii.FishShellfishImmunol2012,33:155-67.19.RenQ,ZhangZ,LiXC,DuJ,HuiKM,ZhangCY,WangW.Threedifferentanti-lipopolysaccharidefactorsidentifiedfromgiantfreshwaterprawn,Macrobrachiumrosenbergii.FishShellfishImmunol2012,33:766-74.20.DuJ,ZhuH,RenQ,LiuP,ChenJ,XiuY,YaoW,MengQ,GuW,WangW.FlowcytometrystudiesontheMacrobrachiumrosenbergiihemocytessub-populationsandimmuneresponsestonovelpathogenspiroplasmaMR-1008.FishShellfishImmunol.2012,33:795-800.21.XiuYJ,WuT,DuJ,YaoW,LiWJ,DingZF,RenQ,GuW,MengQG,WangW.Molecularcharacterizationandexpressionanalysisofextracellularcopper/zincsuperoxidedismutase(ecCuZnSOD)fromorientalriverprawn,Macrobrachiumnipponense.Aquaculture2013,380-383:23-28.22.LongJY,LiM,RenQ*,ZhangCY,FanJ,DuanYY,ChenJ,LiB,DengLH.PhylogeneticandmolecularevolutionoftheADAM(ADisintegrinAndMetalloprotease)genefamilyfromXenopustropicalis,toMusmusculus,Rattusnorvegicus,andHomosapiens.Gene2012507:36-43.23.DingZF,DuJ,OuJT,LiWJ,WuT,XiuYJ,MengQG,RenQ,GuW,XueH,TangJQ,WangW.ClassificationofcirculatinghemocytesfromtheredswampcrayfishProcambarusclarkiiandtheirsusceptibilitytothenovelpathogenSpiroplasmaeriocheirisinvitro.2012,356-357:371-380.24.ZhangCY,WuNN,LiuJ,GeQJ,HuangY,RenQ,FengQC,HeGL.HCVSubtypeCharacterizationamongInjectionDrugUsers:ImplicationforaCrucialRoleofZhenjianginHCVTransmissioninChina.PLoSOne2011,6:e16817.25.RenQ,QiYL,HuiKM,ZhangZ,ZhangCY,WangW.Fourinvertebrate-typelysozymegenesfromtriangle-shellpearlmussel(Hyriopsiscumingii).FishShellfishImmunol.2012,33:909-1526.DuJ,ZhuH,LiuP,ChenJ,XiuY,YaoW,WuT,RenQ,MengQ,GuW,WangW.ImmuneresponsesandgeneexpressioninhepatopancreasfromMacrobrachiumrosenbergiichallengedbyanovelpathogenspiroplasmaMR-1008.FishShellfishImmunol.2013,34:315-2327.LiXC,ZhuL,LiLG,RenQ,HuangYQ,LuJX,Fang,WH,KangW.Anovelmyeloiddifferentiationfactor88homolog,SpMyD88,exhibitingSpToll-bindingactivityinthemudcrabScyllaparamamosain.DevCompImmunol2012,39(4):313-322.28.DingZF,YaoW,DuJ,RenQ,LiWJ,WuT,XiuYJ,MengQG,GuW,XueH,TangJQ,WangW.HistopathologicalcharacterizationandinsituhybridizationofanovelspiroplasmapathogeninthefreshwatercrayfishProcambarusclarkii.Aquaculture2013,380-383:106-113.29.ZhangXW,LiuYY,MuY,RenQ,ZhaoXF,WangJX.OverexpressionofaC-typelectinenhancesbacterialresistanceinredswampcrayfishProcambarusclarkii.FishShellfishImmunol.10.1016/j.fsi.2013.01.020.30.RenQ,ZhongX,YinSW,HaoFY,HuiKM,ZhangZ,ZhangCY,YuXQ,WangW.ThefirstTollreceptorfromthetriangle-shellpearlmusselHyriopsiscumingii.FishShellfishImmunol.10.1016/j.fsi.2013.02.014.