学术学位博导
--> 职称：教授
单位：第一附属医院
专业：内科学（消化系病）
个人简介
发表论文:
Effect of CYP2C19 Genetic Polymorphisms on the Efficacy of Proton Pump Inhibitor-Based Triple Therapy for Helicobacter pylori Eradication: A Meta-Analysis
Prevalence and Risk factors for Helicobacter pylori infection in Chinese population
An Evaluation of a Serologic Test with a Current Infection Marker of Helicobacter pylori Before and After Eradication Therapy in Chinese
Helicobacter pylori infection is associated with decreased serum levels of high density lipoprotein, but not with the severity of coronary atherosclerosis.
Interaction of Helicobacter pylori with genetic variants in the MDM2 promoter, is associated with gastric cancer susceptibility in Chinese patients.
Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.
Efficacy and Tolerability of First-Line Triple Therapy With Levofloxacin and Amoxicillin Plus Esomeprazole or Rabeprazole for the Eradication of Helicobacter pylori Infection and the Effect of CYP2C19
Gastric atrophy and intestinal metaplasis before and after Helicobacter pylori eradication: A meta-analysis
Prophylactic Antibiotics Reduce Pancreatic Necrosis in Acute Necrotizing Pancreatitis: A Meta-Analysis of Randomized Trials
Advantages of Moxifloxacin and Levofloxacin-Based Triple Therapy for Second-line Treatments of Persistent Helicobacter pylori Infection: A Meta Analysis
教材专著:
《肠屏障功能障碍》
《临床病例诊疗剖析—内科学分册
《“三基”训练指南》
科研成果:
肿瘤标志物HCCR多克隆抗体的制备及其在肿瘤早期诊断中的应用
联合检测骨桥蛋白、CD44v6在肿瘤转移中的临床应用
转移相关基因调控肝癌等肿瘤侵袭转移的分子机制及意义
转移相关基因调控肝癌等肿瘤侵袭转移的分子机制及意义
粪便药敏试验检测幽门螺杆菌对抗生素的基因型耐药及其临床应用
幽门螺杆菌诊断、治疗与致病的机制研究
基于细胞色素酶CYP2C19不同基因型的左氧氟沙星三联优化方案用于一线治疗幽门螺杆菌
目前承担的科研项目:
MDM2/P63-Dicer途径调节miRNA106b在幽门螺杆菌致病中的作用
幽门螺杆菌LPS通过SDF1/CXCR4效应轴激活MDM2促进胃上皮细胞恶性转化新发现的机制研究
胃癌早期诊断新型标志物—HCCR抗体的制备及其参与胃癌发生新发现的机制研究
早期胃癌内镜诊疗优化方案的研究
幽门螺杆菌调控Lnc-AK096550诱导SOCS3促进胰岛素抵抗发生的机
已经完成的科研项目:
骨桥蛋白RNA干涉在肝癌基因治疗中的应用研究
骨桥蛋白调控肝癌迁移的分子机制
骨桥蛋白调控SDF-1/CXCR4效应轴激活MMP-2促进肝癌转移新发现的机制研究：一条不依赖于NF-kB和JNK1的新通路
胃癌早期诊断新型标志物—HCCR蛋白单抗制备及其参与胃癌发生的机制研究
