学术学位硕导
--> 职称：副教授
单位：第一附属医院
liuyuan@jsph.org.cn
专业：内科学（传染病）
个人简介
发表论文:
Wnt/β-catenin signaling plays an essential role in α7 nicotinic receptor-mediated neuroprotection of dopaminergic neurons in a mouse Parkinson’s disease model.
Prevalence and associated factors of knee osteoarthritis in a rural Chinese adult population: an epidemiological survey.
Activation of alpha7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: Implications for Parkinson’s disease.
Pre-operative radiographic findings predicting concomitant posterior malleolar fractures in tibial shaft fractures: a comparative retrospective study.
alpha7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.
Mortality and morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty: a meta-analysis.
Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats.
A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.
A case of brucellosis displaying Parkinsonian-like tremor.
教材专著:
肝脏疾病—案例与思考
传染病护理
临床思维导引
传染病护理学
人禽流感防治解读
临床医学概论
科研成果:
一种定量检测乙型肝炎病毒特异性细胞毒性T淋巴细胞的方法
密码子优化的严重发热伴血小板减少综合征病毒核蛋白基因及其核酸疫苗。
RelA基因rs7101916SNP在制备检测丙型肝炎易感性产品中的应用。
慢性乙型肝炎病人自体树突状细胞（DC）疫苗的制备
目前承担的科研项目:
α7烟碱型乙酰胆碱受体对胶质传递的作用及其与帕金森病的相关性研究
α7-nAChRs对星形胶质细胞功能的调控及与肝性脑病的相关性研究
蒽环类药物与内源性靶分子细胞毒性作用机制的亚细胞药代动力学研究
基于质谱的定向蛋白组学对细胞因子和肿瘤多药耐药相关性的研究
α7-nAChRs对脑内免疫细胞的调控及其与帕金森病的相关性研究
江苏省青年医学人才
病毒性肝炎及其肝衰竭个体化精准治疗策略的研究（江苏省医学创新团队）
α7烟碱型乙酰胆碱受体对胶质传递的作用及其与帕金森病的相关性研究
已经完成的科研项目:
