学术学位博导
--> 职称：教授
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单位：口腔外科
jhb@njmu.edu.cn
专业：口腔临床医学（颌面外）
个人简介
江宏兵，男，博士，教授，口腔医学院口腔颌面外科副主任，从事口腔颌面组织缺损修复、口腔颌面肿瘤等临床与基础研究，先后主持包括国家自然基金、973子课题、江苏省自然基金等科研项目6项，发表论文60余篇,其中，SCI收录20余篇。
发表论文:
Phenotypic characterization of craniofacial bone marrow stromal cells: unique properties of enhanced osteogenesis，cell recruitment, autophagy, and apoptosis resistance
Contribution of SATB2 to the stronger osteogenic potential of bone marrow stromal cells from craniofacial bones
α-Smooth muscle actin-positive myofibroblasts, in association with epithelial-mesenchymal transition and lymphogenesis, is a critical prognostic parameter in patients with oral tongue squamous cell c
Focal adhesion kinase serves as a marker of cervical lymph node metastasis and is a potential therapeutic target in tongue cancer
Perioperative glucocorticosteroid treatment delays early healing of a mandible wound by inhibiting osteogenic differentiation
Lithium chloride promotes the odontoblast differentiation of hair follicle neural crest cells by activating Wnt/β-catenin signaling
Roles of SATB2 in Site-Specific Stemness, Autophagy and Senescence of Bone Marrow Mesenchymal Stem Cells
Histone deacetylase 8 suppresses osteogenic differentiation of bone marrow stromal cells by inhibiting histone H3K9 acetylation and RUNX2 activity
Dental Follicle Cells Participate in Tooth Eruption via the RUNX2-MiR-31-SATB2 Loop
RNAi-mediated silencing of Atp6i and Atp6i haploinsufficiency prevents both bone loss and inflammation in a mouse model of periodontal disease
教材专著:
口腔疾病诊断流程与治疗策略
复杂牙拔除术
唇腭裂畸形
科研成果:
分子标记物在预测口腔癌患者预后及指导个体化治疗中的应用
游离上臂外侧皮瓣在口腔颌面部缺损修复中的应用
目前承担的科研项目:
SATB2-Nanog-mTOR 轴调控BMSCs 衰老及其在颌骨增龄性骨量丢失中的作用
PCL聚合物纳米粒子控释HIF-1α诱导OSTERIX修饰的iPS细胞成骨作用及再血管化的研究
巨噬细胞自噬与极化异常促使双膦酸盐性颌骨坏死的机制研究
口腔黏膜鳞癌浸润区微环境重塑与上皮间质转化机制研究
肿瘤微环境中炎症因子介导Snail调控EMT与口腔黏膜鳞癌侵袭转移机制研究
已经完成的科研项目:
口腔癌前沿区成纤维细胞生物学状态及其临床意义的研究
SATB2在颌骨间充质细胞特征性成骨分化中的调控机制
表观遗传修饰不同胚源 MSCs 促进颌骨成骨修复及相关机制研究
颅神经嵴干细胞定向诱导分化成牙复合组织的研究
