学术学位博导
--> 职称：教授
学院：附属淮安第一医院
qlwang@njmu.edu.cn
专业：肿瘤学
个人简介
研究员、博士生导师、医学博士、美国路易斯维尔大学James Graham Brown肿瘤转化研究中心博士后。江苏省“333”工程人才、江苏省“六大人才高峰”高层次人才、江苏省双创博士、江苏省重点青年医学人才。近5年在《JAMA Network open》、《Nature Communications》、《Cancer Research》等国际知名杂志发表SCI论文30多篇；先后负责国家自然科学基金面上项目2项、厅市级课题10多项。目前主要从事肿瘤纳米药物靶向递送系统及食管癌发病、进展机制研究。
发表论文:
Delivery of a chemotherapeutic drug using novel hollow carbon spheres for esophageal cancer treatment
In Silico Meets In Vivo: Towards Computational CRISPR-Based sgRNA Design
Comparative effectiveness and safety between oxaliplatin-based and cisplatin-based therapy in advanced gastric cancer: A meta-analysis of randomized controlled trials
CRISPR-Cas9 for in vivo Gene Therapy: Promise and Hurdles
Grapefruit-derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites
Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids
Aptamer against mannose-capped lipoarabinomannan inhibits virulent Mycobacterium tuberculosis infection in mice and rhesus monkeys
A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan of Bacillus Calmette-Guérin Enhances Immunoprotective Effect against Tuberculosis
Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles
Quantitatively controlling expression of miR-17~92 determines colon tumor progression in a mouse tumor model
教材专著:
现代肿瘤理论与实践
科研成果:
结核分支杆菌糖脂抗原的DNA适配子及其应用
一种能特异性结合BCG糖脂抗原的DNA适配子及其应用
目前承担的科研项目:
适配子介导的靶向多药耐药结肠癌细胞的新型“绿色”共递系统的建立及疗效评估
江苏省“333”工程科研项目，BRA2018234
江苏省“六大人才高峰”科研项目，WSN-260
新型靶向多药耐药结肠癌细胞的“绿色”共递系统的建立及抗瘤效应评估，SBK20150421
适配体介导的靶向HER2+乳腺癌的新型葡萄柚脂质纳米载体的研制及抗癌效应研究，QNRC2016433
适配子介导的靶向多药耐药结肠癌细胞的新型“绿色”共递系统的建立及疗效评估，81572977
炎症相关性受体富集的白细胞浆膜包被的新型“蛋黄脂质纳米递药系统”抗食管鳞癌的实验研究，81772585
淮安市纳米肿瘤学重点实验室，HAP201804
淮安市食管癌生物标本库重点实验室，HAP201606
已经完成的科研项目:
