学术学位博导
--> 职称：教授
学院：鼓楼临床医学院
zyzhou@nju.edu.cn
专业：影像医学与核医学
个人简介
一、研究方向：肿瘤和淋巴结病变的分子和功能MR成像 二、近三年承担科研项目： 1、基于HER-2抗体修饰负载阿霉素金纳米笼对胃癌淋巴结的一体化研究。 江苏省社会发展基金（重点项目）； 50万元； 2015、7-2018、6 2、基于磁性荧光多功能探针USPIO- Cy5.5 双模态成像精确清扫胃癌淋巴结研究。 国家自然科学基金； 75万元； 2014、01－2017、12 3、基于磁性荧光多功能探针USPIO- Cy5.5 双模态成像精确清扫胃癌淋巴结研究。 国家卫生和计划生育委员会（卫生部）； 10万元； 2013、07－2016、06 4、MR近红外双模态探针USPIO-ICG诊断乳腺癌前哨淋巴结研究。 江苏省自然科学基金； 20万元； 2012、07－2015、06 5、MR淋巴造影探测早期宫颈癌前哨淋巴结研究。 江苏省“六大人才高峰”； 5万元；2010、07－2013、06 三、代表性论文： 1、Yu H, Chen J, Liu S, Lu Q, He J, Zhou Z*, Hu Y. Enzyme sensitive, surface engineered nanoparticles for enhanced delivery of camptothecin. J Control Release. 2015 Aug 15;216:111-120. [通信作者] 2、Liu S, Wang H, Guan W, Pan L, Zhou Z, Yu H, Liu T, Yang X, He J, Zhou Z*. Preoperative apparent diffusion coefficient value of gastric cancer by diffusion-weighted imaging: Correlations with postoperative TNM staging. J Magn Reson Imaging. 2015 Sep;42(3):837-43. [通信作者] 3、Huo D, He J, Li H, Huang AJ, Zhao HY, Ding Y, Zhou ZY, Hu Y. X-ray CT guided fault-free photothermal ablation of metastatic lymph nodes with ultrafine HER-2 targeting W18O49 nanoparticles. Biomaterials. 2014 Nov;35(33):9155-66. [通信作者] 4、Huo D, Ding J, Cui YX, Xia LY, Li H, He J, Zhou ZY*, Wang HW, Hu Y.X-ray CT and pneumonia inhibition properties of gold-silver nanoparticles for targeting MRSA induced pneumonia. Biomaterials. 2014, 35(25):7032-41. [通信作者] 5、 Ding Y, Gao J, Yang XY, He J, Zhou ZY*, Hu Y. Preparation of water dispersible, fluorescent Ag–PAA–PVP hybrid nanogels and their optical properties. Adv Powder Technol 2014 JAN;25(1) :183-188. [通信作者] 6、Liu S, He J, Guan W, Li Q, Zhang X, Mao H, Yu H, Zhou Z*. Preoperative T Staging of Gastric Cancer: Comparison of Diffusion- and T2-Weighted Magnetic Resonance Imaging. J Comput Assist Tomogr. 2014 Apr 11. [通信作者] 7、Huo D, He J, Li H, Yu H, Shi T, Feng Y, Zhou Z*, Hu Y. Fabrication of Au@Ag core-shell NPs as enhanced CT contrast agents with broad antibacterial properties. Colloid Surface B . 2014 May 1;117:29-35. [通信作者] 8、Liu S, He J, Guan W, Li Q, Yu H, Zhou Z, Bao S, Zhou Z*. Added value of diffusion-weighted MR imaging to T2-weighted and dynamic contrast-enhanced MR imaging in T staging of gastric cancer. Clin Imaging. 2014;38(2):122-8. [通信作者] 9、Liu S, Guan W, Wang H, Pan L, Zhou Z, Yu H, Liu T, Yang X, He J, Zhou Z. Apparent diffusion coefficient value of gastric cancer by diffusion-weighted imaging: Correlations with the histological differentiation and Lauren classification. Eur J Radiol. 2014 Dec;83(12):2122-8. [通信作者] 10、Zhou Z, Chen H, Lipowska M, Wang L, Yu Q, Yang X, Tiwari D, Yang L, Mao H. A dual-modal magnetic nanoparticle probe for preoperative and intraoperat
发表论文:
阳性亲淋巴对比剂增强MR淋巴成像对淋巴结病变的诊断价值
含弥散加权成像MR和增强CT对胃癌术前T分期准确率的比较
磁共振弥散加权成像对胃癌淋巴结转移的诊断价值
X-ray CT and pneumonia inhibition properties of gold-silver nanoparticles for targeting MRSA induced pneumonia
Preoperative T Staging of Gastric Cancer: Comparison of Diffusion- and T2-Weighted Magnetic Resonance Imaging
Preparation of water dispersible, fluorescent Ag–PAA–PVP hybrid nanogels and their optical properties
Fabrication of Au@Ag core-shell NPs as enhanced CT contrast agents with broad antibacterial properties
Added value of diffusion-weighted MR imaging to T2-weighted and dynamic contrast-enhanced MR imaging in T staging of gastric cancer
A dual-modal magnetic nanoparticle probe for preoperative and intraoperative mapping of sentinel lymph nodes by magnetic resonance and near infrared fluorescence imaging
Silver nanoshells as tri-mode bactericidal agents integrating long term antibacterial, photohyperthermia and triggered Ag+ release capabilities
教材专著:
磁共振成像操作手册
科研成果:
江苏省医学新技术引进奖二等奖
目前承担的科研项目:
基于磁性荧光多功能探针（编号：81371516）
基于磁性荧光多功能探针（编号：W201306）
MR近红外双模态探针USPIO-ICG诊断乳腺癌前哨淋巴结研究（编号：2012省163）
MR淋巴造影探测早期宫颈癌前哨淋巴结研究（编号：73）
南京市卫生青年人才培养工程（第一层次）（编号：25）
MR淋巴造影探测早期宫颈癌前哨淋巴结研究（编号：200905005）
已经完成的科研项目:
