Liu Jinhua，副研究员，硕士生导师


研究方向
(1) 室温荧光纳米材料的制备及其生化传感分析;
(2) 荧光酶联免疫试剂盒的研发；
(3) 柔性纸基生物芯片的研发；

近三年代表性论文

1. Can Chen, Lihua Pang, Rui Wang, Changpeng Zou, Guotong Ruan, Yujie Sun, Chengwu Zhang, Haidong Yu, Lin Li, Jinhua Liu*, Fluorescence copolymer-based dual-signal monitoring tyrosinase activity and its inhibitor screening via blue-green emission transformation, Spectrochim. Acta. A, 2021, 246, 119028
2. Qiaoqiao Ci, Xiaofei Qin, Jinhua Liu*, Rui Wang, Zheng Li, Wenjing Qin, Kah-Leong Lim, Cheng-Wu Zhang* and Lin Li*, Mitochondria-targeted polydopamine nanoprobes for visualizing endogenous sulfur dioxide derivatives in a rat epilepsy model, Chem.Comm., 2020, 56, 11823-11826
3. Jinhua Liu*, Changpeng Zou, Can Chen, Haixiao Fang, Qiong Wu, Haidong Yu, Jixin Zhu*, Lin Li*, Sheng Yang, Wei Huang, Topochemical assembly of levodopa nanoparticles network as a highperformance biosensing platform coupling with π-π stacking and electrostatic repulsion interactions, Talanta, 2020, 219, 121285
4. Can Chen, Changpeng Zou, Lin Li, Haidong Yu, Jixin Zhu, Jinhua Liu*, Wei Huang, Blue and green emission-transformed fluorescent copolymer: Specific detection of levodopa of anti-Parkinson drug in human serum, Talanta, 2020, 214, 120817
5. Yucui Jiao, Chao Du, Lijun Zong, Xueying Guo, Yufeng Han, Xiaopan Zhang, Lin Li, Chengwu Zhang, Qiang Ju, Jinhua Liu*, Hai-Dong Yu*, Wei Huang*, 3D vertical-flow paper-based device for simultaneous detection of multiple cancer biomarkers by fluorescent immunoassay, Sensors & Actuators: B. Chemical, 2020, 306,127239
6. Lijun Zong, Yufeng Han, Lei Gao, Chao Du, Xiaopan Zhang, Lin Li, Xiao Huang, Jinhua Liu,* Hai-Dong Yu * and Wei Huang, A transparent paper-based platform for multiplexed bioassays by wavelength dependent absorbance/transmittance, Analyst, 2019, 144, 7157-7161.
7. Fenghua Geng, Changpeng Zou, Jinhua Liu,* Xueying Guo, Yunchang Fan,* Haidong Yu, Sheng Yang, Zhipeng Liu,* Lin Li, Development of luminescent nanoswitch for sensing of alkaline phosphatase in human serum based on Al³⁺-PPi interaction and Cu NCs with AIE properties, Anal. Chim. Acta., 2019,1076, 131-137.
8. Can Chen, Fenghua Geng, Yongxiang Wang,* Haidong Yu, Lin Li, Sheng Yang, Jinhua Liu,* Wei Huang, Design of a nanoswitch for sequentially multi-species assay based on competitive interaction between DNA-templated fluorescent copper nanoparticles, Cr³⁺ and pyrophosphate and ALP, Talanta, 2019, 205, 120132.
9. Xueying Guo, Lijun Zong,Yucui Jiao,Yufeng Han, Xiaopan Zhang, Jia Xu, Lin Li, Cheng-wu Zhang, Zhipeng Liu, Qiang Ju, Jinhua Liu,* Zhihui Xu,* Hai-Dong Yu,* Wei Huang*, Signal-Enhanced Detection of Multiplexed Cardiac Biomarkers by a Paper-Based Fluorogenic Immunodevice Integrated with Zinc Oxide Nanowires, Anal. Chem. 2019, 91, 9300-9307.
10. Lei Gao, Chengxian Zhu, Lin Li, Chengwu Zhang, Jinhua Liu,* Hai-Dong Yu,* Wei Huang*, All paper-based flexible and wearable piezoresistive pressure sensor, ACS Appl. Mater. Interfaces, 2019, 11, 25034-25042.
11. Can Chen, Shiyu Zhang, Chengwu Zhang, Lin Li, Jixin Zhu, Jinhua Liu*, TMB-assembly as nanosubstrate construction colorimetric kit for highly sensitive and selective detection of H₂O₂ and monoamine oxidase-A based on Fenton reaction, Microchemical Journal, 2019, 150,104177.
12. Xiaofei Qin, Can Chen, Shiyu Zhang, Jixin Zhu, Yongxiang Wang, Jinhua Liu*, Near-infrared emission TMB dots as colorimetric and fluorescent nanoswitch for reversible recognition of iron ion and cysteine and its logic gate application, Analytical Methods, 2019, DOI: 10.1039/C9AY01749F.
13. Xiaofei Qin, Changmin Yu, Jing Wei, Lin Li,* Chengwu Zhang, Qiong Wu, Jinhua Liu, Shao Q. Yao,* and Wei Huang*, Rational design of nanocarriers for intracellular protein delivery, Adv. Mater. 2019, **.
14. Qiaoqiao Ci, Jinhua Liu, * Xiaofei Qin, Linqi Han, Hai Li, Hai-Dong Yu, Kah-Leong Lim, Cheng-wu Zhang, * Lin Li,* Wei Huang, Polydopamine dots-based fluorescent nanoswitch assay for reversible recognition of glutamic acid and Al³⁺ in human serum and living cell, ACS Appl. Mater. Interfaces, 2018, 10, 35760-35769.
15. Shiyu Zhang, #Can Chen, # Xiaofei Qin, Qianchen Zhang, Jinhua Liu,* Jixin Zhu, Yongqian Gao, Lin Li, Wei Huang, Ultrasensitive detection of trypsin activity and inhibitor screening based on the electron transfer between phosphorescence copper nanocluster and cytochrome c, Talanta, 2018, 189, 92-99.
16. Qianchen Zhang, # Shiyu Zhang, # Jinhua Liu,* Jixin Zhu, Chengwu Zhang, Yun Ni, Yongqian Gao, Haidong Yu, Lin Li, * Wei Huang, Surface oxidation -controlled synthesis of blue fluorescence wavelength-tunable mini-size carbon nitride nanosheet and its application, ChemistrySelect, 2018, 3, 2229-2234.
17. Qianchen Zhang, Duoduo Zhao, Chengwu Zhang, Jinhua Liu,* Zhongfu An, Xiaofei Qin, Yongqian Gao,* Shiyu Zhang, Lin Li,* Wei Huang. An effective signal amplifying strategy for copper (II) sensing by using in situ fluorescent proteins as energy donor of FRET. Sensor Actuat B: Chem., 2018, 259, 633-641.