张承武
张承武，研究员


联系方式
地址：南京市新模范马路5号, 南京工业大学丁家桥校区(210009)
电话：+86-
Email: iamcwzhang@njtech.edu.cn

个人简历
2015-至今, 南京工业大学先进材料研究院，研究员
2009-2015，新加坡神经科学研究院，研究员
2005-2009，新加坡中央医院，研究员
2003-2005，汕头大学医学院，博士后
1998-2003，四川大学，生理学博士
1993-1998，山东济宁医学院，预防医学学士

研究方向

研究方向：主要从事中枢神经退行性病变的相关研究，利用细胞、线虫、果蝇、小鼠等多种模型，揭示中枢神经系统损伤的分子机制，近年来结合干细胞、化学、纳米技术，开发帕金森病等中枢性神经系统疾病的诊断及治疗新方法。研究项目获得新加坡国家医学研究基金、江苏省高校自然科学基金重大项目、六大人才高峰-高层次人才、安徽中烟重点实验室开放课题支持；研究成果发表在Nature Communications，Angewandte Chemie-International Edition，ACS Nano，ACS Sensors,Cell death and differentiation，Journal of Neuroscience, Neuodegenerative Diseases，NeuromolecularMedicine，Parkinson’s Disease, Investigative ophthalmology & visual science Advanced，Frontiers inAging Neuroscience 等国际学术期刊, 申请国内及国际专利多项。



代表性论文：
1.Mingrui Weng, Xue Yang, Yun Ni, Chenchen Xu, Hang Zhang, Jinjun Shao*, Nannan Shi, Chengwu Zhang*, Qiong Wu, Lin Li*, Wei Huang.(2019) Deep-red ?uorogenic probe for rapid detection of nitric oxide in Parkinson’s disease models. Sensors and Actuators B: Chemical, 283: 769-775.(Co-corresponding author).
2. Qiaoqiao Ci, Jinhua Liu, Xiaofei Qin, Linqi Han, Hai Li, Haidong Yu, Kahleong Lim, Chengwu Zhang*, Lin Li*, Wei Huang. (2018)Polydopamine Dots-Based Fluorescent Nanoswitch Assay for Reversible Recognition of Glutamic Acid and Al3+ in Human Serum and Living Cell. ACS Applied Materials&Interfaces, 10: 35760-35769.(Co-corresponding author).
3. Linqi Han, Riri Shi, Chenqi Xin, Qiaoqiao Ci, Jingyan Ge, Jinhua Liu, Qiong Wu, Chengwu Zhang*, Lin Li*, Wei Huang. (2018)Mitochondrial specific H2Sn fluorogenic sensor for live cell imaging by rational utilization of a dual-functional-photocage group. ACS Sensors,3: 1622-1626. (Co-corresponding author).
4. Yaqi Ding，Chenqi Xin, Chengwu Zhang*, Kah-Leong Lim, Hang Zhang, ZhenQian Fu, Lin Li* and Wei Huang.(2018) Natural Molecules from Chinese Herbs Protecting against Parkinson’s Disease via Anti-oxidative Stress.Frontiers in Aging Neuroscience, 10: artickle 246 doi: 10.3389/fnagi.2018.00246 (Co-corresponding author).
5. Minrui Weng, Xiaoji Xie, Chao Liu, Kah-Leong Lim, Chengwu Zhang*, Lin Li*. (2018) The Sources of Reactive Oxygen Species and its possible role inthe pathogenesis of Parkinson’s Disease. Parkinson’s Disease, doi.org/10.1155/2018/** (Co-corresponding author).
6. Chao Liu#, Chengwu Zhang#, Yi Zhou, Wan Qing Wong, Liying Corinne Lee, Wei Yi Ong, Sung Ok Yoon, Wanjin Hong, Xin-Yuan Fu, Tuck Wah Soong, Edward Koo, Lawrence Stanton, Kah-Leong Lim, and Zhicheng Xiao, Gavin Dawe. (2018) APP Upregulation Contributes to Retinal Ganglion Cell Degeneration via JNK3. Cell Death and Differentiation,25: 661-676(Co-first author).
7. Chengwu Zhang, Yee Kit Tai, Bing-Han Chai, Katherine C. M. Chew, Eng-Tat Ang, Fai Tsang, Bryce W. Q. Tan, Eugenia T. E. Hong, Abu Bakar Ali Asad, Kai-Hsiang Chuang, Kah-Leong Lim*, Tuck Wah Soogn*. (2017) Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain. Neuromolecular Medicine,19: 375-386.
8. Jinhua Liu*, Duoduo Zhao, Minrui Weng, Chengwu Zhang*, Shiyu Zhang, Jixin Zhu, Yong Feng, Kaimin Shih, Wei Huang. Rational Design of Mini-size Carbon Nitride Nanosheets with Double Excitation- and pH-Dependent Fluorescence Behaviors for Two-photon CellImaging. (2017) CHEMISTRY – AN ASIAN JOURNAL, 12: 535-840(Co-corresponding author).
9.Chengwu Zhang,Liting Hang, Tso-Pang Yao and Kah-Leong Lim*. (2016) Parkin Regulation and Neurodegenerative Disorders.Frontiers in Aging Neuroscience, 7(article 248): 1-15.
10.Chengwu Zhang, Henry Basil Adeline, Bing-Han Chai, Eugenia T.E. Hong, Chee-Hoe Ng, Kah-Leong Lim*. (2016) Pharmacological or genetic activation of Hsp70 protects against loss of parkin function.Neurodegenerative Diseases,16: 304-316.
11. Lin Li#,Chengwu Zhang#,Jing-yan Ge, Linghui Qian, Bing-Han Chai, Qing Zhu, Jun-Seok Lee, Kah-Leong Lim, and Shao-Qin Yao*. (2015) A Small-Molecular Probe for Selective Profiling and Imaging Monoamine Oxidase B Activities in Models of Parkinson’s Disease.Angew. Chem. Int. Ed, 54, 10821–10825(Co-first author).
12. Lin Li#,Chengwu Zhang#, Grace Y.J. Chen, Biwei Zhu, Chou Chai, Qing-Hua Xu, Eng-King Tan, Qing Zhu, Kah-Leong Lim*, Shao-Qin Yao*. (2014) A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease models.”Nature Communications, 5: 3276(Co-first author).