孙 阳，女，1986年2月生。博士，南京工业大学药学院讲师。
一、教育背景
2013.09–2016.06 中国药科大学 药理学 博士
2008.09–2011.07 北京协和医学院 药理学 硕士
2004.09–2008.07 中国药科大学 海洋药学 本科
二、工作经历
2016.09–至今 南京工业大学，药学院，讲师
2012.05–2013.07 默沙东中国有限公司，数据管理专员（药物警戒）
2011.07–2012.04 贝克曼库尔特商贸（中国）有限公司，临床研究专员
三、研究领域
1. 肿瘤药理学
2. 心血管药理学
3. 代谢组学
参与的多项基金项目：
1）非可控性炎症恶性转化调控网络及其分子机制（**） 国家自然科学基金重大研究计划
2）千层纸素肿瘤化学预防机制研究（BK**）江苏省自然科学基金
3）千层纸素逆转肝细胞粘附介导的耐药（CAM-DR）作用及机制研究（**） 国家自然科学基金
4）PLSCR1分子靶点的汉黄芩苷抗AML作用机制研究（国家自然基金资助）
5）抗肿瘤1类药物候选化合物GL-V9的研究（2013ZX09103） 重大专项
四、发表文章
SCI论文10篇（其中第一作者4篇，共同第一作者2篇，其它4篇），文章如下：
1) Sun Yang, Zhao Yue, Yao Jing, Zhao Li, Wu Zhaoqiu, Wang Yu, Pan Di, Miao Hanchi, Guo Qinglong, Lu Na. Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB and NLRP3 inflammasome activation. Biochemical Pharmacology. 2015; 94(2):142-54. doi: 10.1016/j.bcp.2015.02.002. (IF=5.009)
2) Sun Yang¹, Zhao Yue¹, Xiaoping Wang, Zhao Li, Li Wenjun, Ding Youxiang, Pan Chuyue, Guo Qinglong, Na Lu. Wogonoside prevents colitis-associated colorectal carcinogenesis and colon cancer cell proliferation in inflammation-related microenvironment via inhibiting NF-κB activation through PI3K/Akt pathway. Oncotarget. 2016 Apr 18. doi: 10.18632/ oncotarget.8815. (IF=6.359)
3) Sun Yang, Lian Zeqin, Jiang Chunying, Wang Yinghong, Zhu Haibo. Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters. PLoS One. 2012; 7(3):e32115. doi: 10.1371/journal.pone.**. (IF=4.092)
4) Sun Yang, Wang Yinghong, Qu Kai, Zhu Haibo. Beneficial effects of cordycepin on metabolic profiles of liver and plasma from hyperlipidemic hamsters. Journal of Asian Natural Producst Research. 2011; 13(6):534-46. doi: 10.1080/**.2011.575364. (IF=0.944)
5) Zhao Yue¹, Sun Yang¹, Ding Youxiang, Wang Xiaoping, Zhou Yuxin, Li Wenjun, Huang Shaoliang, Li Zhiyu, Guo Qinglong and Lu Na. GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1expression via activation of AMPK/FOXO3a pathway. Oncotarget. 2015 Sep 22;6(28):26291-307. doi: 10.18632/oncotarget.4657. (IF=6.359)
6) Wang Xiaoping¹, Sun Yang¹, Zhao Yue, Ding Youxiang, Zhang Xiaobo, Kong Lingyi, Li Zhiyu, Guo Qinglong, Zhao Li. Oroxyloside prevents dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB pathway through PPARγ activation. Biochemical Pharmacology. 2016; 106: 70-81 doi: 10.1016/j.bcp.2016.02.019. (IF=5.009)
7) Zhao Yue, Wang Xiaoping, Sun Yang, Zhou Yuxin, Yin Yuehan, Ding Youxiang, Li Zhiyu, Guo Qinglong, Lu Na. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells. Apoptosis. 2015; 20(9): 1253-69. doi: 10.1007/s10495-015- 1145-x. (IF= 3.685)
8) Zhao Li, Miao Hanchi, Li Wenjun, Sun Yang, Huang Shaoliang, Li Zhiyu, Guo Qinglong. LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells. Molecular Carcinogenesis. 2015 May 6. doi: 10.1002/mc.22321. [Epub ahead of print] (IF=4.808)
9) Yao Jing, Zhao Li, Zhao Qing, Zhao Yue, Sun Yang, Zhang Yi, Miao Hanchi, You Qidong, Hu Rong, Guo Qinglong. NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis. Cell Death and Disease. (2014) 5, e1283; doi:10.1038/cddis.2014.221(IF=5.014)
10) Wang Yu, Miao Hanchi, Li Wei, Yao Jing, Sun Yang, Li Zhiyu, Zhao Li, Guo Qinglong. CXCL12/CXCR4 axis confers adriamycin resistance to human chronic myelogenous leukemia and oroxylin A improves the sensitivity of K562/ADM cells. Biochemical Pharmacology. 2014; 90 (3): 212-25. doi: 10.1016/j.bcp.2014.05.007. (IF= 4.65)
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