个人简历

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1998.09-2002.06 苏州大学，化学化工学院，学士
2002.09-2005.06 苏州大学，化学化工学院，硕士（导师：纪顺俊教授）
2005.07-2007.10南洋理工大学，化学与生物化学系，硕士（导师：Teck-Peng Loh教授）
2007.11-2010.07 南洋理工大学，化学与生物化学系，研究助理
2010.09-2015.07 慕尼黑大学，化学系，博士（导师：Paul Knochel教授）
2015.07-2015.09 慕尼黑大学，化学系，博士后研究员
2015.11- 2016 南洋理工大学，化学与生物化学系，博士后研究员
2016年至今 南京工业大学，化学与分子工程学院以及先进化学制造研究院，教授




研究方向

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金属有机化学；绿色化学；杂环化合物的合成；不对称合成。





学术成绩

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主要从事金属有机试剂（特别是有机铟金属试剂）的制备及应用、水相及离子液体中绿色有机化学反应的开发、含氟杂环化合物的合成等方面的研究。迄今为止共发表论文70余篇，其中以第一作者（包括共同一作、导师一作本人二作）和通讯作者身份在Chemical Reviews, Chemical Society Reviews, Journal of the American Chemical Society, Angewandte Chemie International Edition, Chem, ACS Catalysis, Green Chemistry, Chemical Communications, Organic Letters, Chemistry—A European Journal, Advanced Synthesis & Catalysis, Organic Chemistry Frontiers, Journal of Organic Chemistry, Tetrahedron Letters等国际权威期刊上发表论文62篇；研究工作受到了国内外同行的广泛关注和点评：两篇论文以封面（frontispiece和back cover）形式发表，一篇论文被审稿人选为Very Important Publication（VIP），两篇论文曾入选ESI高被引论文，一篇论文曾被主编选为ACS Editors' Choice，多篇论文被Synfacts、ChemViews、Noteworthy Chemistry (ACS)、Organic Chemistry Portal、X-MOL等作为亮点进行报道和评述。硕士学位论文分别荣获2005年苏州大学以及2006年江苏省优秀硕士学位论文奖；并荣获2014年国家优秀自费留学生奖学金；入选中国化学会2019联合国“国际化学元素周期表年”49号金属元素铟的代言人。同时作为主要完成人参与的项目“功能性有机分子的合成、性质及应用研究”获得2010年中国石油和化学工业协会科技进步二等奖。



代表性论文

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55. An efficient synthesis of 4,5-diaryl-3,4-dihydropyrimidin-2(1H)-one via a cesium carbonate-promoted direct condensation of 1-aryl-2-propanone with 1,1'-(arylmethylene)diurea
Yi-Cong Guo, Xuan-Di Song, Wei Deng, Weidong Rao, Haiyan Xu,* and Zhi-Liang Shen*
RSC Advances 2020, 10, 30062-30068.
54. Indium-Mediated Difunctionalization of Iodoalkyl-Tethered Unactivated Alkenes via an Intramolecular Cyclization and an Ensuing Palladium-Catalyzed Cross-Coupling Reaction with Aryl Halide
Xuan-Di Song, Xiang-Rui Li, Ya-Wen Wang, Xue-Qiang Chu, Weidong Rao, Haiyan Xu, Guo-Zhi Han,* and Zhi-Liang Shen*
Organic Chemistry Frontiers 2020, DOI: 10.1039/D0QO00632G. (2020 Impact factor: 5.155)
53. Synthesis of Polycyclic Furan and Chromene Derivatives via Cascade Reactions Enabled by Cleavage of Multiple C(sp³)-F Bonds
Ting Xie, Chen Zhang, Si-Xuan Zhang, Weidong Rao, Haiyan Xu, Zhi-Liang Shen,* and Xue-Qiang Chu*
Advanced Synthesis & Catalysis 2020, DOI: 10.1002/adsc.. (2020 Impact factor: 5.851)
52. Copper(II)-Mediated Ring Opening/Alkynylation of Tertiary Cyclopropanols by Using Non-Modified Terminal Alkynes
Bu-Qing Cheng, Si-Xuan Zhang, Yan-Ying Cui, Xue-Qiang Chu, Weidong Rao, Haiyan Xu, Guo-Zhi Han,* and Zhi-Liang Shen*
Organic Letters 2020, 22, 5456-5461 (2020 Impact factor: 6.091)
51. Synthesis of Di(hetero)aryl Sulfides by Defluorinative Sulfenylation of Polyfluoroalkyl Ketones with Sodium Sulfinates or Arylsulfonyl Chlorides
Xue-Qiang Chu,* Ting Xie, Ya-Wen Wang, Xiang-Rui Li, Weidong Rao, Haiyan Xu, and Zhi-Liang Shen*
Chemical Communications 2020, 56, 8699-8702. (2020 Impact factor: 5.996)
50. Selective Quadruple C(sp³)-F Functionalization of Polyfluoroalkyl Ketones
Ting Xie,^# Guo-Qiang Wang,^# Ya-Wen Wang, Weidong Rao, Haiyan Xu, Shuhua Li,* Zhi-Liang Shen,* and Xue-Qiang Chu* (^# Equal contribution)
iScience 2020, 23, 101259. (2020 Impact factor: 4.447)
49. Selective C(sp³)-H Functionalization of Alkyl Esters with N-/S-/O-Nucleophiles Using Perfluoroalkyl Iodide as Oxidant
Shi-Wen Zhao, Song-Zhou Cai, Mao-Lin Wang, Weidong Rao, Haiyan Xu, Lei Zhang, Xue-Qiang Chu,* and Zhi-Liang Shen*
Advanced Synthesis & Catalysis 2020, 362, 3388-3394. (2020 Impact factor: 5.851)
48. An efficient Bi/NH₄I-mediated addition reaction for the highly diastereoselective synthesis of homoallylic alcohols in aqueous media
Zhen Wu, Xue-Xin Feng, Qing-Dong Wang, Xuan-Yu Liu, Weidong Rao, Jin-Ming Yang,* and Zhi-Liang Shen*
Chinese Chemical Letters 2020, 31, 391-395. (2020 Impact factor: 4.632)
47. Iron(0)-mediated Reformatsky Reaction for the Synthesis of β-Hydroxyl Carbonyl Compounds
Xuan-Yu Liu,^# Xiang-Rui Li,^# Chen Zhang, Xue-Qiang Chu, Weidong Rao, Teck-Peng Loh,* and Zhi-Liang Shen* (^# Equal contribution)
Organic Letters 2019, 21, 5873-5878. (2020 Impact factor: 6.091)
46. Chemo- and Regioselective Ring Construction Driven by Visible-Light Photoredox Catalysis: An Access to Modular Fluoroalkylated Oxazolidines Featuring a Quaternary Stereogenic Center
Xue-Qiang Chu, Danhua Ge, Mao-Lin Wang, Weidong Rao, Teck-Peng Loh,* and Zhi-Liang Shen*
Advanced Synthesis & Catalysis 2019, 361, 4082-4090. (2020 Impact factor: 5.851)
45. Regioselective (Hetero)aryl C-H Thianthrenation and Late-stage Transformations
Xue-Qiang Chu, Zhi-Liang Shen,* and Teck-Peng Loh*
Chem 2019, 5, 1025-1027 (Preview). (2020 Impact factor: 19.735)
44. Iron-Mediated Highly Diastereoselective Allylation of Carbonyl Compounds with Cyclic Allylic Halides
Xuan-Yu Liu,^# Bu-Qing Cheng,^# Yi-Cong Guo, Xue-Qiang Chu, Weidong Rao, Teck-Peng Loh,* and Zhi-Liang Shen* (^# Equal contribution)
Organic Chemistry Frontiers 2019, 6, 1581–1586. (2020 Impact factor: 5.155)
43. Lead-Mediated Highly Diastereoselective Allylation of Aldehydes with Cyclic Allylic Halides
Bu-Qing Cheng, Shi-Wen Zhao, Xuan-Di Song, Xue-Qiang Chu, Weidong Rao, Teck-Peng Loh,* and Zhi-Liang Shen*
The Journal of Organic Chemistry 2019, 84, 5348–5356. (2020 Impact factor: 4.335)
42. Preparation of Alkyl Indium Reagents by Iodine-Catalyzed Direct Indium Insertion and Their Applications in Cross-Coupling Reactions
Man-Ling Zhi,^# Bing-Zhi Chen,^# Wei Deng, Xue-Qiang Chu, Teck-Peng Loh,* and Zhi-Liang Shen* (^# Equal contribution)
The Journal of Organic Chemistry 2019, 84, 3017-3023. (2020 Impact factor: 4.335)
41. Oxidant-Directed Chemoselective Sulfonylation and Sulfonyloximation of Alkenes via Cleaving C-S Bond in TosMIC
Xue-Qiang Chu, Danhua Ge, Teck-Peng Loh* and Zhi-Liang Shen*
Organic Chemistry Frontiers 2019, 6, 835-840. (2020 Impact factor: 5.155)
40. Metallic Salt-Catalyzed Direct Indium Insertion into Alkyl Iodides and Their Applications in Cross-Coupling Reactions
Bing-Zhi Chen, Chuang-Xin Wang, Zhen-Hua Jing, Xue-Qiang Chu, Teck-Peng Loh,* and Zhi-Liang Shen*
Organic Chemistry Frontiers 2019, 6, 313-318. (2020 Impact factor: 5.155)
39. Bismuth-Mediated Diastereoselective Allylation Reaction of Carbonyl Compounds with Cyclic Allylic Halides or Cinnamyl Halide
Xuan-Yu Liu, Bu-Qing Cheng, Yi-Cong Guo, Xue-Qiang Chu, Yong-Xin Li, Teck-Peng Loh,* and Zhi-Liang Shen*
Advanced Synthesis & Catalysis 2019, 361, 542-549. (2020 Impact factor: 5.851)
38. Chromium(III)-Catalyzed Addition of Water and Alcohol to α,β-Unsaturated Ketones for The Synthesis of β-Hydroxyl and β-Alkoxyl Ketones in Aqueous Media
Jin-Jin Yun, Xuan-Yu Liu, Wei Deng, Xue-Qiang Chu, Zhi-Liang Shen,* and Teck-Peng Loh*
The Journal of Organic Chemistry 2018, 83, 10898–10907. (2020 Impact factor: 4.335)
37. Visible Light-Mediated Trifluoromethylation of Fluorinated Alkenes via C–F Bond Cleavage
Liu-Hai Wu, Jun-Kee Cheng, Liang Shen, Zhi-Liang Shen,* and Teck-Peng Loh*
Advanced Synthesis & Catalysis 2018, 360, 3894-3899. (2020 Impact factor: 5.851)
36. Indium(III)-catalyzed Hydration and Hydroalkoxylation of α,β-Unsaturated Ketones in Aqueous Media
Jin-Jin Yun, Man-Ling Zhi, Wen-Xiao Shi, Xue-Qiang Chu, Zhi-Liang Shen,* and Teck-Peng Loh*
Advanced Synthesis & Catalysis 2018, 360, 2632-2637. (2020 Impact factor: 5.851)
35. Combining Fluoroalkylation and Defluorination to Enable Formal [3+2+1] Heteroannulation by Using Visible-Light Photoredox Organocatalysis
Xue-Qiang Chu, Ting Xie, Lin Li, Danhua Ge, Zhi-Liang Shen,* and Teck-Peng Loh*
Organic Letters 2018, 20, 2749–2752. (2020 Impact factor: 6.091)
34. Synthesis of Alkyl Indium Reagents by Using Unactivated Alkyl Chlorides and Their Applications in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides
Bing-Zhi Chen, Man-Ling Zhi, Chuang-Xin Wang, Xue-Qiang Chu, Zhi-Liang Shen,* and Teck-Peng Loh*
Organic Letters 2018, 20, 1902–1905 (highlighted by Organic Chemistry Portal). (2020 Impact factor: 6.091)
33. Copper-catalyzed Three-component Cyclization of Amidines, Styrenes, and Fluoroalkyl Halides for the Synthesis of Modular Fluoroalkylated Pyrimidines
Xue-Qiang Chu, Bu-Qing Cheng, Yao-Wei Zhang, Danhua Ge, Zhi-Liang Shen,* and Teck-Peng Loh*
Chemical Communications 2018, 54, 2615-2618 (highlighted by X-MOL). (2020 Impact factor: 5.996)
32. Recent Advances in Radical-Initiated C(sp3)–H Bond Oxidative Functionalization of Alkyl Nitriles
Xue-Qiang Chu, Danhua Ge, Zhi-Liang Shen,* and Teck-Peng Loh*
ACS Catalysis 2018, 8, 258–271 (ACS Editors' Choice; ESI高被引论文). (2020 Impact factor: 12.350)
31. Lewis Acid-catalyzed Selective [2+2]-Cycloaddition and Dearomatizing Cascade Reaction of Aryl Alkynes with Acrylates
Liang Shen, Kai Zhao, Kazuki Doitomi, Rakesh Ganguly, Yong-Xin Li, Zhi-Liang Shen,* Hajime Hirao, and Teck-Peng Loh*
Journal of the American Chemical Society 2017, 139, 13570-13578 (highlighted by Organic Chemistry Portal and X-MOL). (2020 Impact factor: 14.612).
30. Copper-catalyzed Trifluoromethylation of Styrene Derivatives with CF₃SO₂Na
Liu-Hai Wu, Kai Zhao, Zhi-Liang Shen,* and Teck-Peng Loh*
Organic Chemistry Frontiers 2017, 4, 1872-1875. (2020 Impact factor: 5.155)
29. Transition Metal-catalyzed Cross-coupling Reactions Using Organoindium Reagents
Kai Zhao, Liang Shen, Zhi-Liang Shen,* and Teck-Peng Loh*
Chemical Society Reviews 2017, 46, 586-602. (2020 Impact factor: 42.846)
28. Polyfunctional Lithium, Magnesium, and Zinc Alkenyl Reagents as Building Blocks for the Synthesis of Complex HeterocyclesZhi-Liang Shen,^# Vasudevan Dhayalan,^# Andreas D. Benischke,^# Robert Greiner, Konstantin Karaghiosoff, Peter Mayer, and Paul Knochel* (^# Equal contribution)
Angewandte Chemie International Edition 2016, 55, 5332-5336. (2020 Impact factor: 12.959)
27. C₆₀-Catalyzed Preparation of Aryl and Heteroaryl Magnesium and Zinc Reagents using Mg/LiCl
Zhi-Liang Shen, and Paul Knochel*
ACS Catalysis 2015, 5, 2324?2328. (2020 Impact factor: 12.350)
26. Stereoselective Preparation of Polyfunctional Alkenylindium(III) Halides and Their Cross-Coupling with Unsaturated Halides
Zhi-Liang Shen and Paul Knochel*
Chemistry-A European Journal 2015, 21, 7061-7065. (2020 Impact factor: 4.857)
25. Expedient Preparation of Aryllithium and Arylzinc Reagents from Aryl Chlorides Using Lithium 4,4-Di-tert-Butylbiphenylide and Zinc(II) Chloride
Zhi-Liang Shen, Korbinian Sommer, and Paul Knochel*
Synthesis 2015, 47, 2617-2630. (2020 Impact factor: 2.675)
24. Highly Diastereoselective Preparation of Aldol Products Using New Functionalized Allylic Aluminum Reagents
Zhi-Liang Shen, Zhihua Peng, Chun-Ming Yang, Julian Helberg, Peter Mayer, Ilan Marek, and Paul Knochel*
Organic Letters 2014, 16, 956–959. (2020 Impact factor: 6.091)
23. Preparation of Functionalized Organoindium Reagents via Magnesium Insertion to Organic Halides in the Presence of InCl₃ at Room Temperature
Sebastian Bernhardt,^# Zhi-Liang Shen,^# and Paul Knochel* (^# Equal contribution)
Chemistry-A European Journal 2013, 19, 828-833. (2020 Impact factor: 4.857)
(VIP paper; highlighted as frontispiece; also highlighted in ChemViews Magazine).
22. Organoindium Reagents: the Preparation and Application in Organic Synthesis
Zhi-Liang Shen, Shun-Yi Wang, Yew-Keong Chok, Yun-He Xu, and Teck-Peng Loh*
Chemical Reviews 2013, 113, 271-401 (131 pages; invited review). (2020 Impact factor: 52.758)
21. Application of Recyclable Ionic Liquid-Supported Imidazolidinone Catalyst in Enantioselective Diels-Alder Reaction
Zhi-Liang Shen,^# Hao-Lun Cheong,^# Yin-Chang Lai, Wan-Yi Loo, and Teck-Peng Loh* (^# Equal contribution)
Green Chemistry 2012, 14, 2626-2630. (2020 Impact factor: 9.480)
20. Synthesis and Application of Recyclable Ionic Liquid-Supported Imidazolidinone Catalyst in Enantioselective 1,3-Dipolar Cycloaddition
Zhi-Liang Shen,^# Kau Kiat Kelvin Goh,^# Colin Hong An Wong, Wan-Yi Loo, Yong-Sheng Yang, Jun Lu, and Teck-Peng Loh* (^# Equal contribution)
Chemical Communications 2012, 48, 5856-5858. (2020 Impact factor: 5.996)
19. Direct Synthesis of Ester-containing Indium Homoenolate and Its Application in Palladium-catalyzed Cross-coupling with Aryl Halide
Zhi-Liang Shen, Kelvin Kau Kiat Goh, Colin Hong An Wong, Yong-Sheng Yang, Yin-Chang Lai, Hao-Lun Cheong, and Teck-Peng Loh*
Chemical Communications 2011, 47, 4778-4780. (2020 Impact factor: 5.996)
18. Palladium-catalyzed Cross-coupling of Indium Homoenolates with Aryl Halides with Wide Functional Group Compatibility
Zhi-Liang Shen, Yin-Chang Lai, Colin Hong An Wong, Kelvin Kau Kiat Goh, Yong-Sheng Yang, Hao-Lun Cheong, and Teck-Peng Loh*
Organic Letters 2011, 13, 422-425. (2020 Impact factor: 6.091)
17. Direct Synthesis of Water-Tolerant Alkyl Indium Reagents and Their Application in Palladium-Catalyzed Couplings with Aryl Halides
Zhi-Liang Shen, Kau Kiat Kelvin Goh, Yong-Sheng Yang, Yin-Chang Lai, Colin Hong An Wong, Hao-Lun Cheong, Teck-Peng Loh*
Angewandte Chemie International Edition 2011, 50, 511-514 (Highlighted in Noteworthy Chemistry of ACS, 2011, February 14). (2020 Impact factor: 12.959)
16. Synthesis of Water-Tolerant Indium Homoenolate in Aqueous Media and Its Application in the Synthesis of 1,4-Dicarbonyl Compounds via Palladium-Catalyzed Coupling with Acid Chloride
Zhi-Liang Shen, Kau Kiat Kelvin Goh, Hao-Lun Cheong, Colin Hong An Wong, Yin-Chang Lai, Yong-Sheng Yang, and Teck-Peng Loh*
Journal of the American Chemical Society 2010, 132, 15852-15855 (highlighted by Synfacts, 2011, 2, 200). (2020 Impact factor: 14.612)
15. Br?nsted Base-Catalyzed One-Pot Three-Component Biginelli-Type Reaction: An Efficient Synthesis of 4,5,6-Triaryl-3,4-Dihydropyrimidin-2(1H)-one and Mechanistic Study
Zhi-Liang Shen, Xiao-Ping Xu, and Shun-Jun Ji*
The Journal of Organic Chemistry 2010, 75, 1162–1167. (2020 Impact factor: 4.335)
14. Zn/InCl₃-Mediated Pinacol Cross-Coupling Reactions of Aldehydes with α,β-Unsaturated Ketones in Aqueous Media
Yong-Sheng Yang, Zhi-Liang Shen, and Teck-Peng Loh*
Organic Letters 2009, 11, 2213. (2020 Impact factor: 6.091)
13. Indium (Zinc)-Copper-Mediated Barbier-Type Alkylation Reaction of Nitrones in Water: Synthesis of Amines and Hydroxylamines
Yong-Sheng Yang, Zhi-Liang Shen, and Teck-Peng Loh*
Organic Letters 2009, 11, 1209 (highlighted by Synfacts, 2009, 6, 657). (2020 Impact factor: 6.091)
12. Indium-Copper-Mediated Conjugate Addition of Alkyl Halide to α,β-Unsaturated Carbonyl Compounds in Water
Zhi-Liang Shen, Hao-Lun Cheong and Teck-Peng Loh*
Tetrahedron Letters 2009, 50, 1051. (2020 Impact factor: 2.275)
11. One-Pot Chemoenzymatic Syntheses of Enantiomerically-Enriched O-Acetyl Cyanohydrins from Aldehydes in Ionic Liquid
Zhi-Liang Shen, Wei-Juan Zhou, Ya-Ting Liu, Shun-Jun Ji* and Teck-Peng Loh*
Green Chemistry 2008, 10, 283-286. (2020 Impact factor: 9.480)
10. Indium-Silver- and Zinc-Silver-Mediated Barbier-Grignard-Type Alkylation Reaction of Imines by Using Unactivated Alkyl Halides in Aqueous Media
Zhi-Liang Shen, Hao-Lun Cheong and Teck-Peng Loh*
Chemistry-A European Journal 2008, 14, 1875-1880. (2020 Impact factor: 4.857)
9. Indium-Copper and Indium-Silver Mediated Barbier-Grignard-Type Alkylation Reaction of Aldehydes Using Unactivated Alkyl Halides in Water
Zhi-Liang Shen, Yan-Lin Yeo and Teck-Peng Loh*
The Journal of Organic Chemistry 2008, 73, 3922-3924 (highlighted by Synfacts 2008, 3, 861). (2020 Impact factor: 4.335)
8. Indium(III) Iodide-Mediated Strecker Reaction in Water: an Efficient and Environmentally Friendly Approach for the Synthesis of α-Aminonitrile via a Three-Component Condensation
Zhi-Liang Shen, Shun-Jun Ji* and Teck-Peng Loh*
Tetrahedron 2008, 64, 8159-8163. (2020 Impact factor: 2.233)
7. Indium-Copper-Mediated Barbier-Grignard-Type Alkylation Reaction of Imines in Aqueous Media
Zhi-Liang Shen and Teck-Peng Loh*
Organic Letters 2007, 9, 5413-5416 (highlighted by Synfacts, 2008, 3, 296). (2020 Impact factor: 6.091)
6. Ultrasound-Promoted Alkynylation of Ethynylbenzene to Ketones under Solvent-Free Condition
Shun-Jun Ji,* Zhi-Liang Shen, Da-Gong Gu and Xiao-Ying Huang
Ultrasonics Sonochemistry 2005, 12, 161-163. (2020 Impact factor: 6.513)
5. A Novel Base-Promoted Synthesis of β-Indolylketones via a Three-Component Condensation under Ultrasonic Irradiation
Zhi-Liang Shen, Shun-Jun Ji,* Shun-Yi Wang and Xiao-Fei Zeng
Tetrahedron 2005, 61, 10552-10558. (2020 Impact factor: 2.233)
4. Ionic Liquid [omim]PF₆ as an Efficient and Recyclable Reaction Media for the Cyanosilylation of Aldehydes without Lewis Acid or Any Special Activation
Zhi-Liang Shen, Shun-Jun Ji* and Teck-Peng Loh*
Tetrahedron Letters 2005, 46, 3137-3139. (2020 Impact factor: 2.275)
3. An Environmentally Friendly Procedure for Mukaiyama Aldol and Mukaiyama–Michael Reactions Using a Catalytic Amount of DBU under Solvent- and Metal-Free Conditions
Zhi-Liang Shen, Shun-Jun Ji* and Teck-Peng Loh*
Tetrahedron Letters 2005, 46, 507-508. (2020 Impact factor: 2.275)
2. An Efficient Synthesis of Ferrocenyl Substituted 1,5-Diketone and Cyclic α,β-Unsaturated Ketones under Ultrasound Irradiation
Shun-Jun Ji,* Zhi-Liang Shen, Da-Gong Gu and Shun-Yi Wang
Journal of Organometallic Chemistry 2004, 689, 1843-1848. (2020 Impact factor: 2.304)
1. Aldol condensation of acetylferrocene under ultrasound
Shun-Jun Ji,* Zhi-Liang Shen, and Shun-Yi Wang
Chinese Chemical Letters 2003, 14, 663-666. (2020 Impact factor: 4.632)





沈志良 教授
Email：ias_zlshen@njtech.edu.cn