个人简历

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2016-至今 南京工业大学，先进化学制造研究院，教授
2015-2016 美国宾夕法尼亚大学化学系(Upenn)，博士后
2013-2015 美国宾夕法尼亚大学，联合培养博士
2009-2015 中国农业大学，应用化学系，硕士/博士
2005-2009 河北农业大学，学士




研究方向

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不对称催化，有机合成：


1.廉价金属催化的交叉偶联反应及其在药物及天然产物合成中的应用。
2.碱金属催化的弱酸性化合物C(sp³)-H键官能团化及应用。
3.药物、天然产物及生物活性分子全合成。


学术成绩

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本课题组在过渡金属催化的不对称交叉偶联反应以及串联反应等前沿领域具有丰富的研究经验及基础。首次实现了廉价Co催化的高对映选择性的交叉偶联反应，为不对称交叉偶联开辟了新方向，相应研究成果发表于JACS上。初次探索了Pd催化的甲苯化合物的不对称烯丙基烷基化（AAA）反应，研究结果发表于著名化学期刊Angew. Chem., Int. Ed上，该工作被Synfact作为亮点工作重点报道。迄今为止共发表SCI论文26篇，其中，以第一作者与通讯作者在Nature Communications, Journal of American Chemical Society, Angewandte Chemie International Edition, Organic Letters等国际权威期刊发表论文16篇。单篇最高影响因子（IF）12.113.
目前主持国家和江苏省自然科学基金项目各一项。申请专利10项，授权6项：
10. 毛建友，关海星，一种（S）-2-芳基丙酸酯类化合物的合成方法专利号：7.9
9. 毛建友，凌搏，杨文军，一种β,β-二取代丙酸酯衍生物的合成方法，专利号：
0.0。
8. 毛建友，关海星，一种邻位二胺类化合物的合成方法，专利号：9.4。
7. 毛建友，徐鑫宇，王志婷，刘国晴，一种2-取代吲哚类化合物的合成方法，专利号： 5.5
6. 边庆花；钟江春；毛建友；郑冰；刘飞鹏；王敏；李硕宁，一种不对称催化合成（S）-2-芳基丙酸酯的方法，专利号： Zl 2014 1 **.7
5. 钟江春；边庆花；毛建友；刘飞鹏；郑冰；王敏；武林；杨燕青，一种不对称催化合成（S）-芳姜黄酮的新方法，专利号： Zl 2014 1 **.X
4. 钟江春；边庆花；毛建友；刘飞鹏；郑冰；李硕宁；武林，不对称催化合成（S）-非诺洛芬的方法，专利号： Zl 2014 1 **.8
3. 钟江春；李志愿；郑冰；毛建友；郭红超；王敏，一种高光学活性对映体合成海洋天然产物的方法，专利号： Zl 2010 1 **.5
2. 钟江春；李志愿；郑冰；毛建友；郭红超；王敏，一种手性环丙烷氨基醇配体化合物及其制备与应用，专利号：Zl 2010 1 **.4
1. 边庆花；钟江春；王敏；郑冰；刘飞鹏；毛建友；杨燕青，不对称催化合成（S）-萘普生的方法，专利号： Zl 2014 1 **.8




代表性论文

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25. Haixing Guan, Qianwen Zhang, Patrick J. Walsh* and Jianyou Mao,* Nickel/Photoredox-Catalyzed Asymmetric Reductive Cross-Coupling of Racemic α-Chloro Esters with Aryl Iodides. Angew. Chem., Int. Ed. 2020，59, 5172. (SCI一区，IF=12.257)




24. Wenjun Yang, Bo Ling, Bowen Hu, Haolin Yin, Jianyou Mao,* and Patrick J. Walsh* , Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed Umpolung 1,4-Addition of Aryl Iodides to Enals. Angew. Chem., Int. Ed. 2019，DOI:10.1002/anie.. (SCI一区，IF=12.257)

23. Jianyou Mao,* Zhiting Wang, Xinyu Xu, Guoqing Liu, Runsheng Jiang, Haixing Guan, Zhipeng Zheng, Patrick J. Walsh* Synthesis of indoles via domino reaction of 2-fluorotoluenes and nitriles. Angew. Chem., Int. Ed. 2019，58, 11033-11038. (SCI一区，IF=12.257)

22. Liu Guoqing, Walsh Patrick J.*, Mao Jianyou*. Alkaline-Metal-Catalyzed One-Pot Aminobenzylation of Aldehydes with Toluenes Org. Lett. 2019，21, 8514-8518. (SCI一区，IF= 6.555)


21. Guan Haixing, Cao Xianzhong, Walsh Patrick J.*, Mao Jianyou*. One-Pot Aminoalkylation of Aldehydes: Diastereoselective Synthesis of Vicinal Diamines with Azaarylmethylamines Org. Lett. 2019，21, 8679?8683. (SCI一区，IF= 6.555)

20. Shi, X.; Zhou, Y.; Liu, F.; Mao, J.; Zhang, Y.; Shan, T., Modeling of chiral gas chromatographic separation of alkyl and cycloalkyl 2-bromopropionates using cyclodextrin derivatives as stationary phases. J. Chromatogr. A 2019, 1596, 161.
19. Wang, H.; Chen, S.; Liu, G.; Guan, H.; Zhong, D.; Cai, J.; Zheng, Z.; Mao, J.*; Walsh, P. J.*, Synthesis of Diaryl Selenides via Palladium-Catalyzed Debenzylative Cross-Coupling of Aryl Benzyl Selenides with Aryl Bromides. Organometallics 2018, 37, 4086. (SCI二区，IF = 4.1)

18. Wang, Z.; Zheng, Z.; Xu, X.; Mao, J.*; Walsh, P. J.* One-pot aminobenzylation of aldehydes with toluenes. Nat. Commun. 2018, 9, 3365-3373. (SCI一区，IF = 12.353)

17. Mao, J.*; Zhang, J.; Zhang, S.; Walsh, P. J.* NIXANTPHOS: a highly active ligand for palladium catalyzed Buchwald-Hartwig amination of unactivated aryl chlorides Dalton Trans. 2018, 47, 8690. (SCI二区，IF = 4.099)

16. Lin, T.; Mi, J.; Song, L.; Gan, J.; Luo, P.; Mao, J.*; Walsh, P. J. * Nickel-Catalyzed Desymmetrizing Cross-Electrophile Coupling of Cyclic Meso-Anhydrides. Org. Lett. 2018, 20, 1191. (SCI一区，IF = 6.579)

15. Jia, T.; Zhang, M.; McCollom, S. P.; Bellomo, A.; Montel, S.; Mao, J.; Dreher, S. D.; Welch, C. J.; Regalado, E. L.; Williamson, R. T.; Manor, B. C.; Tomson, N. C.; Walsh, P. J. J. Am. Chem. Soc. 2017, 139, 8337. (SCI一区，IF = 13.858)
14. Zhang, S.; Kim, B.-S.; Wu, C.; Mao, J.*; Walsh, P. J.* Palladium-catalysed synthesis of triaryl(heteroaryl)methanes. Nat. Commun. 2017, 8, 14641. (SCI一区，IF=12.353)
Before Nanjing Tech

13. Mao, J.; Zhong, J.; Wang, B.; Jin, J.; Li, S.; Gao, Z.; Yang, H.; Bian, Q*. Synthesis of panaxytriol and its stereoisomers as potential antitumor drugs. Tetrahedron Asymmetry 2016, 27, 330.
12. Shi, X.; Liu, F.; Mao, J. The CGC enantiomer separation of 2-arylcarboxylic acid esters by using β-cyclodextrin derivatives as chiral stationary phases Anal. Chim. Acta. 2016, 912, 156.
11. Mao, J.; Zhang, J.; Jiang, H.; Bellomo, A.; Zhang, M.; Gao, Z.; Dreher, S. D.; Walsh, P. J.: Palladium-Catalyzed Asymmetric Allylic Alkylations with TolueneDerivatives as Pronucleophiless, Angew. Chem., Int. Ed. 2016, 55, 2526. (SCI一区，IF = 11.709)
10. Mao, J.; Li, S.; Zhong, J.; Wang, B.; Jin, J.; Gao, Z.; Yang, H.; Bian, Q.: Total synthesis of panaxydol and its stereoisomers as potential anticancer agents, Tetrahedron: Asymmetry, 2016, 27, 69.
9. Sha, S.; Jiang, H.; Mao, J.; Bellomo, A.; Jeong, S. A.; Walsh, P. J.: Nickel-Catalyzed Allylic Alkylation with Diarylmethane Pronucleophiles: Reaction Development and Mechanistic Insights, Angew. Chem., Int. Ed., 2016, 55, 1070.
8. Liu, F.; Zhong, J.; Li, S.; Li, M.; Wu, L.; Wang, Q.; Mao, J.; Liu, S.; Zheng, B.; Wang, M.; Bian, Q.: Total Syntheses of (R)-Strongylodiols C and D, J. Nat. Prod, 2016, 79, 244.
7. Mao, J.; Eberle, K.; Zhang, J.; Rodríguez-Escrich, C.; Xi, Z.; Pericàs, M. A.; Walsh, P. J.: Synthesis of Triarylmethanols via Tandem Arylation/Oxidation of Diarylmethanes, Tetrahedron Lett. 2015, 56, 3604 .
6. Mao, J.; Liu, F.; Wang, M.; Wu, L.; Zheng, B.; Liu, S.; Zhong, J.; Bian, Q.; Walsh, P. J.: Cobalt-Bisoxazoline-Catalyzed Asymmetric Kumada Cross-Coupling of Racemic α-Bromo Esters with Aryl Grignard Reagents, J. Am. Chem. Soc. 2014, 136, 17662. (SCI一区，IF= 13.858)
5. Mao, J.; Jia, T.; Frensch, G.; Walsh, P. J.: Palladium-Catalyzed Debenzylative Cross-Coupling of Aryl Benzyl Sulfides with Aryl Bromides: Synthesis of Diaryl Sulfides, Org. Lett, 2014, 16, 5304. (SCI一区，IF=6.579)
4. Mao, J.; Nie, X.; Wang, M.; Wang, Q.; Zheng, B.; Bian, Q.; Zhong, J.: Catalytic Asymmetric Nitroaldol (Henry) Reactions with Copper(II)/Cyclopropane-Based Bisoxazoline Complexes, Tetrahedron: Asymmetry, 2012, 23, 965.
3. Zheng, B.; Li, S.; Mao, J.; Wang, B.; Bian, Q.; Liu, S.; Zhong, J.; Guo, H.; Wang, M.: Highly Enantioselective Addition of 1,3-Diynes to Aldehydes Catalyzed by a Zinc–Amino Alcohol Complex, Chem. Eur. J. 2012, 18, 9208.
2. Li, Z.-Y.; Wang, M.; Bian, Q.-H.; Zheng, B.; Mao, J.; Li, S.-N.; Liu, S.-Z.; Wang, M.-A.; Zhong, J.-C.; Guo, H.-C.: Highly Enantioselective Addition of Trimethylsilylacetylene to Aldehydes Catalyzed by a Zinc-Amino-Alcohol Complex, Chem. Eur. J. 2011, 17, 5782.
1. Zheng, B.; Wang, M.; Li, Z.; Bian, Q.; Mao, J.; Li, S.; Liu, S.; Wang, M.; Zhong, J.; Guo, H.: Asymmetric Henry Reaction Catalyzed by a Zn-Amino Alcohol System, Tetrahedron: Asymmetry 2011, 22, 1156.




毛建友 教授
Email:ias_jymao@njtech.edu.cn