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南通大学神经再生重点实验室导师教师师资介绍简介-李贵才

本站小编 Free考研考试/2021-03-27




李贵才(Guicai Li,E_mail:gcli1981@ntu.edu.cn),博士,副研究员,硕士生导师。于2012年6月获得西南交通大学材料学工学博士学位。现任中国生物材料学会神经修复材料分会秘书长,为江苏省“青蓝工程”优秀青年骨干教师培养对象。主持承担国家自然科学基金青年项目,国家自然科学基金面上项目,江苏省自然科学基金青年基金项目,江苏省高校自然科学基金面上项目,南通大学创新人才基金,南通大学教学改革项目等多项科研项目。并作为骨干成员参与国家重点研发计划(科技部)等项目。主讲/参讲本科生《生物材料概论》以及《再生医学》等课程。以通讯作者或第一作者等身份共发表SCI论文40余篇,累计影响因子达110.6,H-index达17,总引用次数达450余次,单篇引用最高达130余次,获中国发明专利4项。并获得南通市第九届自然科学优秀论文一等奖。目前担任Biomaterials,Materials Science and Engineering, Carbohydrate Polymers, Colloids andSurfaceB:Biointerfaces等多个国际SCI期刊的邀请审稿人。
主要研究方向包括(Research Interests):
1)功能化/智能化生物材料的研究(Research on Functionalized/Smart Biomaterials):材料表面功能化、智能化构建以调控细胞行为并加速组织再生过程,并揭示相关机制;
2)组织工程人工植入器件的研发(Research and Development of Tissue Engineering ArtificialImplants)根据不同组织结构及生理特征的差异构建适应于不同组织的可植入器件,并实现组织损伤修复。
3)生物制造(Biofabrication)采用不同加工方法和技术,设计、制备具有不同理化性能和生物学功能的生物材料(装置),并优化制备工艺;
4)神经再生及有效功能精准重建的实现(Realization of nerveregeneration and accurate functional reconstruction):利用生物材料并结合材料表面改性技术实现神经再生过程及功能的有效精准重建;
发表的代表性论著(#为共同一作):
1)Guicai Li, ChengbinXue, Hongkui Wang,Xiaoming Yang, Yinxin Zhao, Luzhong Zhang, Yumin Yang. Spatially FeaturedPorous Chitosan Conduits with Micropatterned Inner Wall and Seamless Sidewallfor Bridging Peripheral Nerve Regeneration. 2018, 194, 225-235.
2)YinxinZhao#, Yingjie Wang#, ChangmeiNiu, Luzhong Zhang, Guicai Li*(通讯), Yumin Yang*. Construction ofpolyacrylamide/graphene oxide /gelatin/sodium alginate (PAM/GO/Gel/SA)composite hydrogel for promoting Schwann cells growth. Journal of BiomedicalMaterials Research A. In Press,2018.
3)Guicai Li*,Qinzhi Xiao,Luzhong Zhang, Yahong Zhao, Yumin Yang*.Nerve growth factor loaded heparin/chitosan scaffolds for acceleratingperipheral nerve regenerationa.Carbohydrate Polymers 2017,171, 39–49.
4)Guicai Li*, Qinzhi Xiao, Ryan McNaughton, Lei Han,Luzhong Zhang, Yaling Wang, Yumin Yang*.Nanoengineered porous chitosan/CaTiO3 hybrid scaffolds for accelerating Schwanncells growth in peripheral nerve regeneration. Colloids and Surfaces B:Biointerfaces 2017,158, 57–67.
5)Guicai Li#, Yinxin Zhao#, Luzhong Zhang,Ming Gao, Yan Kong and Yumin Yang*, Preparation of GrapheneOxide/polyacrylamide Composite Hydrogel and its Effect on Schwann CellsAttachment and Proliferation. Colloids and Surfaces B-Biointerfaces. 2016, 143,547-556.
6)YanKong, Yinxin Zhao, Bing Ji, Beibei Shi, Siying Wei, GuanyiChen,Luzhong Zhang, Guicai Li(通讯), YuminYang.Preparation and characterizationof polyacrylamide/silk fibroin/graphene oxide composite hydrogel for peripheralnerve regeneration. Journal of Biomaterials and Tissue Engineering,2016,6,682–689.
7)Guicai Li#, Luzhong Zhang, YuminYang*,Tailoring ofChitosan Scaffolds with Heparin and γ-aminopropyltriethoxysilane for PromotingPeripheral Nerve Regeneration, Colloids and Surface B:Biointerfaces,2015, 134(3),411-422.
8)Guicai Li, Yan Kong, Yinxin Zhao, Yahong Zhao, LuzhongZhang, Yumin Yang. Fabrication and characterization of polyacrylamide/silkfibroin hydrogels for peripheral nerve regeneration. Journal of BiomaterialsScience, Polymer Edition, 2015,26, 899–916.
9)Guicai Li, CaipingWang,PingYang,JieZhou,PingchuanZhu.Interactionbetween heparin and fibronectin: using quartz crystal microbalance withdissipation, immunochemistry and isothermal titration calorimetry.Journal ofWuhan University of Technology-Mater. Sci. Ed. 2015,30,074-1084.
10)Guicai Li, Qifei Xu, Ping Yang.Inhibiting Smooth Muscle Cell Proliferation via Immobilization ofHeparin/Fibronectin Complexes on Titanium Surfaces. Biomedical AndEnvironmental Sciences. 2015,28,378-382.
11)Guicai Li#, Xueying Zhao#,Weixin Zhao, Luzhong Zhang, Caiping Wang, Maorong Jiang, XiaosongGu*, YuminYang*, Porous Chitosan Scaffolds with Surface Micropatterning and Inner Porosityand Their Effects on Schwann Cells, Biomaterials, 2014,35 (6), 8503-8513.
12)Guicai Li#, Xueying Zhao#, Luzhong Zhang, Caiping Wang, Yunwei Shi,Yumin Yang*, Regulating Schwann Cells Growth by Chitosan Micropatterning forPeripheral Nerve Regeneration In Vitro.Macromolecular Bioscience, 2014,14 (22):1067-1075. (Cover story)
13)Guicai Li, Luzhong Zhang, Caiping Wang, Xueying Zhao,Changlai Zhu, Yanhong Zheng, Yaling Wang, Yahong Zhao, Yumin Yang*, Effect ofSilanization on Chitosan Porous Scaffolds for Peripheral Nerve Regeneration,Carbohydrate Polymers, 2014,101(5):718-726.
14) Guicai Li, Bing Xie, Changjiang Pan,Ping Yang, Hongyan Ding, Nan Huang. Facile Conjugation of Heparin onto TitaniumSurfaces via Dopamine Inspired Coatings for Improving Blood Compatibility.Journal of Wuhan University ofTechnology-Mater. Sci. Ed. 2014,29,832-840.
15) Caiping Wang#,Guicai Li#, Yunwei Shi,Xiaochuan Zhang, Jianlong Li, Zhiwei Wang*, Fei Ding*, Xinmiao Liang*,Neuroprotective Effect of Schizandrin A on Oxygen and GlucoseDeprivation/Reperfusion-Induced Cell Injury in Primary Culture of Rat CorticalNeurons, Journal of Physiology and Biochemistry, 2014, 70(3): 735-747
16)Guicai Li, Ping Yang*, Nan Huang, Hongyan Ding. Responses ofplatelets and endothelial cells to heparin/fibronectin complex on titanium: Insitu investigation by quartz crystal microbalance with dissipation andimmunochemistry. Journal of Bioscience and Bioengineering. 2013,116,235-245.
申请/授权专利
1)李贵才,张鲁中,杨宇民。一种内壁具有取向性结构的多孔人工神经导管的制备方法 公开号: CNA 2016.02
2)杨宇民,顾晓松,李贵才,丁斐。 一种用于组织损伤修复的生物补片 公开号:CNA 2016.07
3) 张鲁中,杨宇民,李贵才,王彩萍。载有神经营养因子的纳米微球及制
备和用途。2015, 授权专利号:CN A.
4)张鲁中,杨宇民,周友浪,李贵才。一种负载甲强龙的纳米微球及其制
备方法和应用2015, 授权专利号:CN A.





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