吕明生 | PhD
吕明生，教授，硕士生导师。博士毕业于上海海洋大学。承担本科生的微生物学、动物寄生虫病学、食品卫生检验、组织胚胎学和研究生的高级微生物学等教学工作。发表论文100余篇，获发明专利15项，连云港市“521工程”第二层次培养对象。
研究方向：
1.海洋微生物的分离纯化以及鉴定
2.微生物产酶纯化和性质研究
3.食品生物活性物质研究
4.纳米材料与生物大分子之间的相互作用及其生物学毒性。
主要研究项目：
1.海洋节杆菌右旋糖酐酶的结构功能解析及分子改造研究（**）国家自然科学基金项目2015-2018
2.新型海洋右旋糖酐酶规模化制备技术及其制品的研究（BE**）江苏省科技厅社会发展科技支撑计划项目2013-2016
3.新型海洋低温淀粉酶规模化开发和工业应用关键技术研究（-8）国家海洋公益性行业科研专项经费项目2012-2015
4.海洋右旋糖苷酶的中试及前期应用研究（2011AA**）国家”863计划”项目2011-2014
代表性论文：
1.Yongli Chen, Deependra Tyagi,Mingsheng Lyu,Andrew J. Carrier, Collins Nganou, Brian Youden, Wei Wang, Shufen Cui, Mark Servos, Ken Oakes, Shengnan He*, and Xu Zhang*, Regenerative NanoOctopus Based on Multivalent-Aptamer-Functionalized Magnetic Microparticles for Effective Cell Capture in Whole Blood, Analytical Chemistry, 2019,DOI: 10.1021/acs.analchem.8b0543.
2.Yi Ding, Le Liu, Yaowei Fang, Xu Zhang,Mingsheng Lyu*,Shujun Wang*，The Adsorption of Dextranase onto Mg/Fe-Layered Double Hydroxide，Nanomaterials,2018, 8 (3): 173-186
3.Wei Ren, Ruanhong Cai, Wanli Yan,Mingsheng Lyu,Yaowei Fang,Shujun Wang*, Purification and characterization of a biofilm-degradable dextranase from a marine bacterium Marine Drugs, 2018, 16(2):51-671.
4.Wanli Yan, Lide Gu, Shu Liu,Wei Ren,Mingsheng Lyu*,Shujun Wang*, Identification of a highly specific DNA aptamer for Vibrio vulnificus using systematic evolution of ligands by exponential enrichment coupled with asymmetric PCR, Journal of Fish Diseases, 2018, 41(12): 1821-1829.
5.Lide Gu, Wanli Yan, Shu Liu,Wei Ren,Mingsheng Lyu*, Trypsin enhances aptamer screening: A novel me thod for targeting proteins, Analytical Biochemistry, 2018, 561:89-95.
6.Lide Gu, Runjhun Saran, Wanli Yan, Po-Jung Jimmy Huang,Shujun Wang,Mingsheng Lyu*, Juewen Liu*, Reselection yielding a smaller and more active silver-specific DNAzyme,ACS Omega, 2018,3:15174-15181.
7.Le Liu, Yi Ding,Shujun Wang, Yaowei Fang,Mingsheng Lyu*, Dextrans Removal from Sugarcane Juice using Dextranase from Marine BacteriumArthrobacter oxydansKQ11, Quality Assurance and Safety of Crops & Foods, 2018,11 (1) :53 – 59.
8.Kori A. Andrea, Li Wang* Andrew J. Carrier, Melanie Campbell, Margaret Buhariwalla, MacKenzi Mutch,Stephanie L. MacQuarrie, Craig Bennett, Martin Mkandawire, Ken Oakes,Mingsheng Lu*, and Xu Zhang*, Adsorption of Oligo-DNA on Magnesium Aluminum-Layered Double Hydroxide Nanoparticle Surfaces: Mechanistic Implication in Gene Delivery，Langmuir, 2017, 33 (16):3926–3933.
9.Zhi Shan,Mingsheng Lu,Dennis E. Curry, Stefanie Beale, Stephen Campbell, Kristin M. Poduska, J. Craig Bennett, Ken D. Oakes，Xu Zhang*，Regenerative Nanobots Based on Magnetic Layered Double Hydroxide for Azo Dye Removal and Degradation, Chemical Communications, 2017, 53 (75):10456-10458.
代表性专利：
1.吕明生，王淑军,李秋潼，任伟，房耀维，刘姝，焦豫良，来自海洋的亚罗酵母FA2-3及其所产低温淀粉酶与产酶方法，中国, 2018.7.6，ZL9.X
2.吕明生,王淑军,蔡阮鸿,房耀维,焦豫良,刘姝,来自海洋的节杆菌及其产低温右旋糖酐酶的方法, 2015.4.22,中国, ZL 7.9
3.吕明生,王淑军,蔡阮鸿,房耀维,焦豫良,刘姝,中国,一种分离纯化缘管浒苔铁超氧化物歧化酶的方法, 2015.10.21,8.7
电子邮箱：mingshenglu@hotmail.com