唐伟方:男，1966年4月生，教授，药物化学专业博士研究生导师，现任中国药科大学理学院副院长。
研究方向：（一）化学药物的设计与合成：主要从事抗肿瘤和心血管药物的设计、合成和构效关系研究，研究侧重于通过合理药物设计及计算机辅助药物设计、合成和生物活性评价，发现具有临床前研究价值的先导化合物。（二）有机合成化学。主持和参与了国家自然科学基金(**)，江苏省自然科学基金，中央高校基本科研业务费专项基金重点基础研究等多项科研项目。在陆涛课题组指导和培养研究生，本课题组目前承担多项国家和省自然基金项目，并与多家药企进行新药联合开发，科研经费充足。2015年课题组发现的1.1类抗肿瘤新药临床前化合物以5000****民币转让给上市公司上海复星医药。主编和参编学术著作和教材8本，申请中国发明专利5项，其中2项已获授权。在Eur. J. Med. Chem.、J. Org. Chem.、Adv. Synth. Catal.等国际学术期刊发表SCI论文20多篇。
联系电话：.
Email:tangwf126@126.com
近年发表的主要论文：
[1]Lu Wang, Gaoyuan Zhu, Qing Zhang, Chunqi Duan, Yanmin Zhang, Zhimin Zhang, Yujun Zhou, Tao LU*, Weifang Tang*.Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.Organic & Biomolecular Chemistry. 2017,15,3455-3465
[2]Lu Wang, Qing Zhang, Gaoyuan Zhu, Zhimin Zhang, Li Zhang, Tianxiao Mao, Xiang Zhou, Yadong Chen, Tao LU*, Weifang Tang*. Design, synthesis and evaluation of derivatives based on pyrimidies scaffold as potent Pan-Raf inhibitors to overcome resistance.Eur. J. Med. Chem.2107,130,86-106
[3] Jing Cao, Shuding Dong, Delu Jiang, Peiyu Zhu, Han Zhang, Rui Li, Xuanyu Wang, Weifang Tang* and Ding Du*.β-Functionalization of Indolin-2-one-Derived Aliphatic Acids for the Divergent Synhesis of Spirooxindoleγ-Butyrolactones.J. Org. Chem. 2017.82.4186-4193
[4] Yong Zhu, Ting Ran, Xin Chen, Jiaqi Niu, Shuang Zhao, Tao Lu and Weifang Tang*.Synthesis and Biological Evaluation of 1-(2-Aminophenyl)-3-arylurea Derivatives as Potential EphA2 and HDAC Dual Inhibitors.Chem. Pharm. Bull. 2016,64,1136-1141
[5]Weifang Tang and Ding Du. Access to spiro and fused indole derivatives fromα,β-unsaturated aldehydes enabled byN-heterocyclic carbene catalysis.Chem. Rec.2016,16,1489-1500
[6]Yu Jiao, Fei Huang, Pengfei Xu, Yanmin Zhang, Shanfyan, Danfeng Zhang,Tao Lu and Weifang Tang.Discovery and Optimization of 1-(4-chloro-3-(trifluoromethyl) phenyl)-3-(2-amino)pyridine- 3-yl)ureas as Novel KDR Kinase Inhibitors.Med. Chem.2016,12,328-337
[7]Yu Jiao, Bo-Tao, Yanmin Zhang, Jianbing Wu, Xiaolin Lu, Ying Zheng, Weifang Tang*, Xiang Zhou*.Design, synthesis and evaluation of novel 2-(1H-imidazol- 2-yl)pyridine derivatives as potential BRAF inhibitors and anti-tumor agents.Eur. J. Med. Chem.2105,90,170-183
[8] Weimin Yang, Yadong Chen, Xiang Zhou, Yazhou Gu, Wenqi Qian, Fan Zhang, Tao Lu*, Weifang Tang* . Design, sythesis and biological evalution of bis-aryl ureas and amides based on 2-amino-3 purinypyridine scaffold as DFG-out B-Raf kinase inhibitors.Eur. J. Med. Chem.2015,89,581-596
[9] Weimin Yang, Yadong Chen, Yanmin Zhang, Sanzhi Tang ,Hongli Chen, Weifang Tang* and Tao Lu*. Design, Sythesis and Antitumor Activities of Bis- arylureas and Bis-arylamines Based on 1H-benzo[d]imidazole Woiety as Novel B-RafV600E/ VEGFR2 Dual Inhibitors.Lett Drug Des Discov.2014,11, 1079- 1089
[10] Zeng Wu, Ming Yan, Shi-He Hu, Zhi-Cheng Yu, Yong Zhu, Ya-Dong Chen, Hai-Chun Liu, Yan-Min Zhang, Si-Hui Yao, Wei-Fang Tang*, Tao Lu*. Design, sythesis and biological evalution of indole derivatives as novel inhibitors taegeting B-Raf kinase.Chinese Chemlett.2014,25,351-354
[11]. Yingyan, Weifang Tang, Yu Zhang, Ding Du, and Taolu. N-Heterocyclic Carbene-Catalyzed Annulations of Enals and Ynals with Indolin-3-ones: Synthesis of 3,4-Dihydropyrano[3,2-b] indol-2-ones.Adv. Synth. Catal. 355:321-326, 2013.
[12] Yong Zhu, Xin Chen, Zeng Wu, Yixuan Zheng, Yadong Chen, Weifang Tang*, Tao Lu*. Synthesis and Antitumor Activity of Novel Diaryl Ether Hydroxamic Acids Derivatives as Potential HDAC Inhibitors.Arch Pharm Res.2012,35(10): 1723-1732
[13].Botao Xin, Weifang Tang, Yue Wang, Guowu Lin, Haichun Liu, Yu Jiao, Yong Zhu, Haoliang Yuan, Yadong Chen, Yao Lu*. Dessign, sythesis and biological evalution of β-carboline derivatives as novel inhibitors targeting B-Raf kinase.Bioorg. Med. Chem. Lett.22(4): 4783-4786, 2012.