韩进松博士(Prof. Dr. Jinsong Han)
中国药科大学工学院，教授，博士生导师


联系方式：
Email: jinsong.han@cpu.edu.cn
中国江苏省南京市江宁区，龙眠大道639号，实训楼410 邮政编码: 211168
课题组主页: www.jinsonglab.com

课题组研究主要集中在机器学习、组合化学、计算化学等策略快速设计及合成新型材料用于构建便携式荧光阵列传感器，并应用于生物医学等领域(例如临床疾病诊断，食品和药品质量控制)。同时，应用计算机辅助药物设计、机器学习、高通量筛选等技术制备及合成小分子药物应用于治疗癌症等疾病。近三年在Chem (CellPress), Nature Biotechnology, Angew. Chem. Int. Ed., PNAS等国际权威期刊上发表论文20余篇，工作受到包括英国广播公司BBC, 科学杂志社SCIENCE, 细胞杂志社CELL，新华社和科学网等超过100多家国内外知名媒体及杂志社的专访和新闻报道。
研究方向(Research Interest)：
(1) 新型荧光阵列传感器（化学舌头）用于疾病诊断及食品药品安全检测
(2) 机器学习及计算机辅助药物设计的抗肿瘤药物设计与药物合成
(3) 人工智能、机器学习、大数据分析用于食品药物真伪及临床疾病的快速诊断检测
本课题组热忱欢迎本科生、硕士生、博士研究生、博士后研究人员的加入
You are welcome to join our Lab as graduates or postdoc
学习与工作经历(Experience)：
2019-至今，中国药科大学工学院，教授，博导，课题组长。
2017-2019，[瑞典] Karolinska Institutet, Bioengineering，博士后
2014-2017，[德国] Universit?t Heidelberg, Chemistry，博士学位（Supervisor: Uwe Bunz）
2010-2013，第二军医大学，药物化学，医学硕士学位
2006-2010，中国药科大学，中药学，学士学位

近年代表作（Publication, 2016-2019）：
16) F. Li#, Jinsong Han# (Equal contribution), T. Cao, W. Lam, B. Fan, W. Tang, S. Chen, Kin Lam Fok* and L. Li*: Design of self-assembly dipeptide hydrogels and machine learning via their chemical features. PNAS,2019, 116(23), 11259-11264. (IF=9.580)
Highlighted in “MITTechnology Review”.
15) B. Wang, Jinsong Han, H. Zhang, A. Biella, M. Bender, K. Seehafer, U. H. F. Bunz*: Detecting Counterfeit Brandies. Chem. Eur. J.2018, 24, 17361-17366. (IF=5.160)
14) B. Wang, Jinsong Han, N. M. Bojanowski, M. Bender, C. Ma, K. Seehafer, A. Herrmann, U. H. F. Bunz*: An Optimized Sensor Array Identifies All Natural Amino Acids. ACS Sens.2018, 3, 1562-1568. (IF=6.944)
Selected as “Cover” by editors
13) B. Wang#, Jinsong Han# (Equal contribution), M. Bender, S. Hahn, K. Seehafer, Uwe Bunz*: Poly(para-phenyleneethynylene)-Sensor Arrays Discriminate 22 Different Teas. ACS Sens. 2018, 3, 504–511. (IF=6.944)
12) Jinsong Han, H. Cheng, B. Wang, M. S. Braun, X. Fan, M. Bender, W. Huang, C. Domhan, W. Mier, T. Lindner, K. Seehafer, M. Wink, U. H. F. Bunz: Polymer/Peptide Complex-Based Sensor Array Discriminates Bacteria in Urine.Angew. Chem. Int. Ed.2017, 56, 15246-15251. (IF=12.257)
Highlighted as a “Hot Paper”
10) B. Wang#, Jinsong Han#(Equal contribution), C. Ma, M. Bender, K. Seehafer, A. Herrmann, U. H. F. Bunz: A Simple Optoelectronic Tongue Discriminates Amino Acids. Chem. Eur. J. 2017, 23, 12471-12474. (IF=5.160)
Highlighted as a “Hot Paper” by the editors
9) Jinsong Han, C. Ma, B. Wang, M. Bender, M. Bojanowski, M. Hergert, K. Seehafer, A. Herrmann, U. H.F. Bunz: A Hypothesis-Free Sensor Array Discriminates Whiskies for Brand, Age, and Taste. Chem (Cell Press). 2017, 2, 817-824.(IF=18.205)
Previewed Article by Prof. V. M. Rotello.Chem (Cell Press). 2017, 2, 755-756.
Highlighted in over 100 Newspapers, Journals, Radio and TV programs(部分选取的媒体新闻报导):
Science News | AAAS,EurekAlert | AAAS,Chemical & Engineering News 2017,96(24) p9, BBC (Interview),Cell (Interview),Deutschlandfunk(Interview),CAMPUS TV(TV Interview),ScienceNewsline,Popular Science,Heidelberg University Press Release,Phys.org, Daily Record, XINHUANET(新华网),CGTN(中国国际电视台),News.cn(新华社),Sciencenet(科学网新闻),X-MOL(新闻),THE PAPER(澎湃新闻),Sina(新浪新闻),Sohu(搜狐新闻), etc.
8) B. Wang#, Jinsong Han#(Equal contribution), M. Bender, K. Seehafer, U. H. F. Bunz: Array-Based Sensing of Explosives by Water-Soluble Poly(pphenyleneethynylene)s. Macromolecules2017, 50, 4126-4131. (IF=5.997)
7) Jinsong Han, B. Wang, M. Bender, J. Pfisterer, W. Huang, K. Seehafer, M. Yazdani, V. M. Rotello, C. M. Rotello, U. H. F. Bunz: Fingerprinting antibiotics with PAE-based fluorescent sensor arrays. Polymer Chemistry2017, 8, 2723-2732.
6) Jinsong Han, B. Wang, M. Bender, K. Seehafer, U. H. F. Bunz: Poly(p-phenyleneethynylene)-based tongues discriminate fruit juices. Analyst2017, 142, 537-543.
Highlighted in ChemistryWorld (RSC)
5) Jinsong Han, B. Wang, M. Bender, S. Kushida, K. Seehafer, U. H. F. Bunz: Poly(aryleneethynylene) Tongue Identifies Nonsteroidal Anti-inflammatory Drugs in Water: A Test Case for Combating Counterfeit Drugs. ACS Appl. Mater. Interfaces 2017, 9, 790–797. (IF=8.456)
4) Jinsong Han, B. Wang, M. Bender, K. Seehafer, U. H. F. Bunz: Water-Soluble Poly(p-aryleneethynylene)s: A Sensor Array Discriminates Aromatic Carboxylic Acids. ACS Appl. Mater. Interfaces2016, 8, 20415–20421. (IF=8.456)
3) Jinsong Han, M. Bender, K. Seehafer, U. H. F. Bunz: Identification of White Wines by using Two Oppositely Charged Poly(p-phenyleneethynylene)s Individually and in Complex. Angew. Chem. Int. Ed.2016, 55, 7689-7692. (IF=12.257)
Highlighted inAngew. Chem. Int. Ed. Press Release,Chemical & Engineering News 2016, 94(26), 9,Analytik-News,ChemistryViews,X-MOL,PHYSORG news,chemie.de,Yumda,EATON,WijnWijs.eu,IDW,analytica-world.com,q-more.chemie.de,Spektrum.de,LABORWELT,Pro-Physik.de,innovations-report, etc.
2) Jinsong Han, M. Bender, S. Hahn, K. Seehafer, U. H. F. Bunz: Polyelectrolyte Complexes Formed from Conjugated Polymers: Array-Based Sensing of Organic Acids.Chem. Eur. J.2016, 22, 3230-3233. (IF=5.160)
1) Jinsong Han, Y. Chen, C. Yang, T. Liu, M. Wang, H. Xu, L. Zhang, C. Zheng, Y. Song, J. Zhu*: Structure-based Optimization Leads to the Discovery of NSC765844, A Highly Potent, Less Toxic and Orally Efficacious dual PI3K/mTOR Inhibitor.European Journal of Medicinal Chemistry. 2016, 24, 957-966.

专利（Patents）：
1) Uwe.H.F. Bunz, Kai Seehafer,Jinsong Han, Markus Bender. (10% share)
Method for identifying a complex analyte. WO2018/055056 A1
2) Ju Zhu, Yunlong Song, Jinsong Han, Ying Chen, Jiaguo Lv, Youjun Zhou. N-(5-(quinolin-6-yl)pyridin-3-yl) benzsulfamide derivatives, preparation method and therapeutic use thereof. PCT/CN2013/086349; WO A1; US A1; CN A; CNA; EP**A1; EP**A4. Oct 31, 2013.
3) Ju Zhu, Jingjing Huang, Ying Chen, Jinsong Han, Canhui Zheng, Youjun Zhou, Jiaguo Lv, Chongqing Wang, Hao Zhou, Wei Tian, Nannan Sun. 3, 4-dihydroisoquinoline antitumor compounds as well as preparation method and application thereof. CN (A); CN (B), Jul 24, 2013.