张艳敏，药学信息学博士，硕士生导师，哈佛大学访问****。主要从事抗肿瘤及抗病毒等领域新药分子设计与开发，计算机辅助药物设计和人工智能药物设计方法学研究，医药大数据与人工智能药物设计自动化平台搭建等。主持国家自然科学基金和江苏省自然科学基金共2项，主持省级教改项目1项。在J.Med.Chem., Eur.J.Med.Chem., J.Chem.Inf.Model., Mol.Phar.等国际学术期刊发表研究论文20余篇。

教育及工作经历：
2018/03–至今 中国药科大学 医药信息与生物统计系 讲师
2015/09–2017/09哈佛大学 化学与化学生物学系 访问****
2011/09–2017/12 中国药科大学 药学信息学 博士
2007/09–2011/06 中国药科大学 信息管理与信息系统 本科
主要研究方向：
1. 计算机辅助药物设计新方法及应用性研究
2. 人工智能药物设计新方法及应用性研究
近期代表作：
[1] Xingye Chen^(#), Wuchen Xie^(#), Yan Yang, Yi Hua, GuoMeng Xing, Li Liang, Chenglong Deng,Yuchen Wang, Yuanrong Fan, Haichun Liu, Tao Lu, Yadong Chen^(*),and Yanmin Zhang^(*), Discovery of Dual FGFR4 and EGFR Inhibitors by Machine Learning and Biological Evaluation, J. Chem. Inf. Model., 2020, 60, 4640?4652
[2] Guomeng Xing, Li Liang, Chenglong Deng, Yi Hua, Xingye Chen, Yan Yang, Haichun Liu, Tao Lu, Yadong Chen^(*), and Yanmin Zhang^(*), Activity Prediction of Small Molecule Inhibitors for Antirheumatoid Arthritis Targets Based on Artificial Intelligence, ACS Comb. Sci., 2020. (Accepted)
[3] Xingye Chen^(#), Haichun Liu^(#), Wuchen Xie, Yan Yang, Yuchen Wang, Yuanrong Fan, Yi Hua, Lu Zhu, Junnan Zhao, Tao Lu, Yadong Chen^(*)and Yanmin Zhang^(*), Investigation of Crystal Structures in Structure-Based Virtual Screening for Protein Kinase Inhibitors, J. Chem. Inf. Model., 2019, 59(12): 5244?5262
[4] Yuchen Wang^(#), Haichun Liu^(#), Yuanrong Fan, Xingye Chen, Yan Yang, Lu Zhu, Junnan Zhao, Yadong Chen^(*)and Yanmin Zhang^(*), In Silico Prediction of Human Intravenous Pharmacokinetic Parameters with Improved Accuracy, J. Chem. Inf. Model., 2019, 59(9): 3968?3980
[5] Yuanrong Fan^(#), Yanmin Zhang^(#), Yi Hua, Yuchen Wang, Lu Zhu, Junnan Zhao, Yan Yang, Xingye Chen, Shuai Lu, Tao Lu^(*), Yadong Chen^(*),Investigation of Machine Intelligence in Compound Cell Activity Classification, Mol. Pharm., 2019, 16(11): 4472~4484
[6] Lu Wang^(#), Yanmin Zhang^(#), Qing Zhang, Gaoyuan Zhu, Zhimin Zhang, Chunqi Duan,, Tao Lu^(*), Weifang Tang^(*),Discovery of potent Pan-Raf inhibitors with increased solubility to overcome drug resistance, Eur. J. Med. Chem., 2019, 163: 243~255
[7] Yanmin Zhang, Yadong Chen, Danfeng Zhang, Lu Wang, Tao Lu^(*), Yu Jiao^(*), Discovery of Novel Potent VEGFR-2 Inhibitors Exerting Significant Antiproliferative Activity against Cancer Cell Lines, J. Med. Chem., 2018, 61(1): 140~157
[8] Yanmin Zhang^(#), Lu Wang^(#), Qing Zhang, Gaoyuan Zhu, Zhimin Zhang, Xiang Zhou,, Yadong Chen, Tao Lu^(*), Weifang Tang^(*), Potent Pan-Raf and RTKs inhibitors based on cyclopropyl formamide fragment overcome resistance, J. Chem. Inf. Model.,2017, 57(6): 1439~1452
招生方向：药学信息学（分子模拟及药物设计方向）
生物与医药（医药大数据与人工智能方向）
联系方式：yanminzhang@cpu.edu.cn