陆涛：男，1963年4月出生，教授，药物化学专业博士生导师，江苏省教学名师，现任中国药科大学副校长。1984年7月毕业于原南京药学院药物化学专业获学士学位，1989年6月毕业于中国药科大学药物化学专业获硕士学位，2001年5月毕业于中国药科大学药物化学专业获博士学位。2004年5月被聘为教授。2006年11月被聘为博士生导师。2000年10月任基础部副主任，2003年2月任基础部主任，2012年7月任理学院院长。2013年7月任中国药科大学副校长。
现担任国家基金委生命科学部的通讯评议专家，国家发改委药品价格论证中心评审专家；教育部本科教学合格评估专家；江苏化学化工学会理事、有机化学专业委员会委员等学术职务。《中国药科大学学报》编委，多次受邀为EuropeanofMedicinalChemistry、JournalofMolecularModeling等多种SCI期刊担当审稿人。
课题组主要研究方向：（一）药物分子设计与合成：（1）抗肿瘤信号转导通路KDR抑制剂、c-Met抑制剂、Raf激酶抑制剂、CDK抑制剂、Polo-likekinase抑制剂、HDAC抑制剂等研究；（2）抗糖尿病药物SGLT2抑制剂、GPR40激动剂研究；（二）高通量虚拟筛选和药物分子设计；（三）有机化学方法学研究；（四）药物生物统计与计算药学；（五）医药企业信息化管理系统。已完成国家及省部级课题多项，目前课题组在研项目主要有国家自然科学基金9项、教育部博士点基金3项、江苏省自然科学基金2项；教育部外国文教专家基金一项；在校企合作方面，与“湘北威尔曼制药股份有限公司和广州威尔曼新药研发中心有限公司”、“福州海王福药制药有限公司”、“南京圣和药业有限公司”、“浙江海翔药业股份有限公司”等建立了长期的合作关系。每年可使用科研经费在二百万元以上。已指导硕士研究生24名，指导博士研究生4名。课题组现有指导教师12名，博士生9名，硕士研究生46名。


近期发表主要论著：
1.YongZhu,Hui-FangLi,ShuaiLu,Yi-XuanZheng,ZengWu,Wei-FangTang,XiangZhou,TaoLu*.Investigationontheisoformselectivityofhistonedeacetylaseinhibitorsusingchemicalfeaturebasedpharmacophoreanddockingapproaches.Eur.J.Med.Chem2010,45(5),1777–1791
2.HuifangLi,YadongChen,ShashaRao,XiumeiChen,HaichunLiu,WeifangTang,YueWang,XiangZhou,TaoLu^*.RecentAdvancesintheResearchandDevelopmentofB-RafInhibitors.Curr.Med.Chem.2010,17,1618-1634
3.YueWang,Guo-WuLin,JinHong,LiLi,Yu-MeiYang,TaoLu.Synthesis,structure,DNAbindingandcleavageabilityofanewcopperciprofloxacincomplex.JournalofCoordinationChemistry2010,63(20),3662–3675
4.HaoliangYuan,TaoLu,TingRan,HaichunLiu,ShuaiLu,WentingTai,YingLeng,WeiweiZhang,JianWang,andYadongChen*NovelStrategyforThree-DimensionalFragment-BasedLeadDiscovery.J.Chem.Inf.Model.2011,51,959–974
5.DingDu,*,YingyanLu,JianlinJin,WeifangTang,TaoLu,*N-Heterocycliccarbene-catalyzedhydroacylationofisatinswithaldehydes:accessto3-acyloxy-1,3-dihydro-2H-indol-2-ones.Tetrahedron2011,67,7557-7562
6.ShuaiLu,Hai-ChunLiu,Ya-DongChen,*Hao-LiangYuan,Shan-LiangSun,Yi-PingGao,PeiYang,LiangZhangandTaoLu*,CombinedPharmacophoreModeling,Docking,and3D-QSARStudiesofPLK1Inhibitors.InternationalJournalofMolecularSciences2011,12,8713-8739
7.TingRan,TaoLu,HaoliangYuan,HaichunLiu,JianWang,WeiweiZhang,YingLeng,GuowuLin,ShulinZhuang,YadongChen*,AselectivitystudyonmTOR/PI3Kαinhibitorsbyhomologymodelingand3D-QSAR,J.Mol.Model.2012,18(1),171-186
8.Guo-WuLin,YueWang,Qiao-MeiJin,Tao-TaoYang,Jie-MeiSong,YiLu,Qing-JieHuang,KeSong,JunZhou,TaoLu*,Synthesis,structuresandthebiologicalactivitystudyonthemetalcomplexesof2-(4-aminophenyl)benzothiazolederivative.InorganicaChimicaActa2012,382,35-42
9.Du,Ding*;Hu,Zhongyuan;Jin,Jianlin;Lu,Yingyan;Tang,Weifang;Wang,Bo;Lu,Tao*.N-HeterocyclicCarbene-CatalyzedThree-ComponentDominoReactionofAlkynylAldehydeswithOxindoles.OrganicLetters2012,14(5),1274-1277
10.YueWang,QiaomeiJin,GuowuLin,TaotaoYang,ZhanweiWang,YiLu,YiminTang,LifangLiu,TaoLu*,SynthesisandStructureoftheβ-CarbolineDerivativesandTheirBindingIntensitywithCyclin-DependentKinase2.Chem.Pharm.Bull.2012,60(4),435–441
11.QingfaZhou*,XuepingChu,WeifangTang,TaoLu*,Anefficientone-potsynthesisof1,4-disubstituted3-amino-2-pyridonederivativesviathree-componentreactionsofalkynylaldehydesandamineswithethyl2-((diphenylmethylene)amino)acetate.Tetrahedron68(2012)4152-4158
12.BotaoXin,WeifangTang,YueWang,GuowuLin,HaichunLiu,YuJiao,YongZhu,HaoliangYuan,YadongChen*,TaoLu*,Design,synthesisandbiologicalevalutionofβ-carbolinederivativesasnovelinhibitorstargetingB-Rafkinase.Bioorganic&MedicinalChemistryLetters22(2012)4783–4786
13.WenhaiLi*,YueWang,TaoLu*,Facilesynthesisof1-aminoisoquinolinesviathetandemreactionsof2-alkynylbenzaldoximeswithisothiocyanates.Tetrahedron68(2012)6843-6848
14.ShuaiLu,Shan-LiangSun,Hai-ChunLiu,Ya-DongChen*,Hao-LiangYuan,Yi-PingGao,PeiYangandTaoLu*,IdentificationofNovelPolo-likeKinase1InhibitorsbyaHybridVirtualScreening.ChemicalBiology&DrugDesign2012;80:328–339
15.QianLu,ShuaiLu,XinghuaGao,YubinLuo,BeiTong,ZhifengWei,TaoLu,YufengXia,GuixinChou,ZhengtaoWangandYueDai*.Norisoboldine,analkaloidcompoundisolatedfromRadixLinderae,inhibitssynovialangiogenesisinadjuvant-inducedarthritisratsbymoderatingNotch1pathway-relatedendothelialtipcellphenotype.ExperimentalBiologyandMedicine2012,237:919-932
16.YanminZhang,HaichunLiu,YuJiao,HaoliangYuan,FengxiaoWang,ShuaiLu,SihuiYao,ZhipengKe,WentingTai,YuleiJiang,YadongChen*,TaoLu*,DenovodesignofN-(pyridin-4-ylmethyl)anilinederivativesasKDRinhibitors:3D-QSAR,molecularfragmentreplacement,protein-ligandinteractionfingerprint,andADMETprediction.MolDivers2012,16:787–802
17.YingyanLu,WeifangTang,YuZhang,DingDu*andTaoLu*,N-HeterocyclicCarbene-CatalyzedAnnulationsofEnalsandYnalswithIndolin-3-ones:Synthesisof3,4-Dihydropyrano[3,2-b]indol-2-ones.Adv.Synth.Catal.2013,355,321–326
18.ChenWang,De-KaiYe,Yun-YiWang,TaoLu*andXing-HuaXia*,Insightsintothe‘‘freestate’’enzymereactionkineticsinnanoconfinement.LabonaChip2013,13,1546–1553
19.Fang-RongYan*,YuanHuang,Jun-LinLiu,TaoLu*,Jin-GuanLin*,BayesianInferenceforGeneralizedLinearMixedModelBasedontheMultivariatetDistributioninPopulationPharmacokineticStudy.PLOSONE2013,8(3)e58369
20.Qing-FaZhou*,Xue-PingChu,Fei-FeiGe,ChengLi,TaoLu*,Stereoselectivesynthesesoffunctionalizedspirocyclopenteneoxindolesviatriphenylphosphine-catalyzed[3+2]cycloadditionreactions.Mol.Divers.(2013)17:563–571
联系地址：江苏省南京市童家巷24号，中国药科大学（210009）
电话：025-83271086，025-86185086
传真：025-83302827
E-mail:lutao@cpu.edu.cn