杨勇，男，1976年12月生，教授，博士生导师。现任中国药科大学药物科学研究院副院长、新药安全评价研究中心主任。2000年获得临床医学学士学位，2005年获得药理学博士学位，一直以来基于转化医学开展肿瘤发病机制及个体化治疗新策略的研究。在国际权威学术期刊如JBC、CDD、Carcinogenesis等累计发表SCI论文30余篇，获得授权专利1项。一篇SCI论文入选科技部中国科学技术信息研究所评出的“2008年中国百篇最具影响国际学术论文”。2009年入选教育部“新世纪优秀人才计划”，并同时被选为江苏省“333高层次人才培养工程”中青年科学技术带头人和江苏省“六大人才高峰”高层次人才。
2007年至2011年作为项目负责人分别承担国家自然科学基金重大研究计划1项，国家自然科学基金面上项目和青年基金各1项，并承担江苏省自然科学基金2项；2011年承担科技部“十二五重大新药创制专项”1项。2012年荣获江苏省首届江苏省杰出青年基金。2005年获得“江苏省科技进步一等奖”和“中华医学三等奖”，2007年荣获“江苏省科技进步二等奖”。兼任江苏省药理学会常务理事、江苏省药理学会青年药理专业委员会主任委员、国家自然科学基金评审专家、全国高等医药院校药学类统编教材编委和PNAS、Cancerresearch等多个国际学术期刊的特约审稿人。

联系电话：025-86185622，电子邮件：valianty@hotmail.com

近年来发表的论文：
1.ZhangWB,WangZ,SuF,JinYH,LiuHY,WangQJ,YangY*.ActivationofAMP-activatedproteinkinasebytemozolomidecontributestoapoptosisinglioblastomacellsviap53activationandmTORC1inhibition.JBiolChem.2010,285,52:40461–40471.（Correspondingauthor）
2.Qing-yiZhu,ZhuoWang,ChaoJi,Yan-liYang,Yong-huaJin,Qiu-juanWang,Zhi-gangBi,Gang,Hu,YongYang*.C6-Ceramidesynergisticallypotentiatestheanti-tumoreffectsofhistonedeacetylaseinhibitorsviaAKTde-phosphorylationandα-tubulinhyper-acetylationbothinvitroandinvivo.CellDeath&Disease.(2011)2,e117;doi:10.1038/cddis.2010.96.（Correspondingauthor）
3.Hai-xiaJi,Yu-lianZou,Jing-jingDuan,Zhi-rongJia,Xian-jingLi,ZhuoWang,LiLi,YongwenLi,Gen-yanLiu,Ming-QingTong,Xiao-yiLi,Guo-huiZhang,Xiang-rongDai,LingHe,ZhiyuLi,CongCao,YongYang*.TheSyntheticMelanocortin(CKPV)2ExertsAnti-FungalandAnti-InflammatoryEffectsagainstCandidaalbicansVaginitisviaInducingMacrophageM2Polarization.PLoSONE.2013,8(2):e56004.（Correspondingauthor）
4.ChenFei-Hong;ZhangLin-Bo;QiangLei;YangZhen;WuTian;ZouMei-Juan;TaoLei;YouQi-Dong;LiZhi-Yu;YangYong*;GuoQing-Long.Reactiveoxygenspecies-mitochondriapathwayinvolvedinLY-202-inducedapoptosisinhumanhepatocellularcarcinomaHepG(2)cells.Cancerletters.2010;296(1):96-105.(Correspondingauthor）
5.YongYang,Xian-jingLi,ZhenChen,Xuan-xuanZhu,JingWang,Lin-boZhang,QiangLei,Yan-junMa,Zhi-yuLi,Qing-longGuo,Qi-dongYou.Wogonininducedcalreticulin/AnnexinA1exposuredictatestheimmunogenicityofcancercellsinaPERK/AKTdependentmanner.PLoSONE.2012,7(12):e50811.
6.QiangL,YangY,YouQD,MaYJ,etal.Isolationandcharacterizationofcancerstemlikecellsinhumanglioblastomacelllines.Cancerletters.2009，279(1):13-21.（Co-firstauthor）
7.LeiQiang,YongYang,Qi-DongYou,Yan-JunMa,etal.Inhibitionofglioblastomagrowthandangiogenesisbygambogicacid:aninvitroandinvivostudy.BiochemicalPharmacology.2008,75(5):1083-92.（Co-firstauthor）
8.JunY,GuoQL,YouQD,ZhaoL,GuHY,YangY,ZhangHW,TanZ,WangX.GambogicacidinducedG2/MphasecellcyclearrestviadisturbingCDK7mediatedphosphorylationofCDC2/P34inhumangastriccarcinomaBGC-823cells.Carcinogenesis.2007,28(3)632-8.
9.YongYang,LanYang,Qi-DongYou,Fei-FeiNie,Hong-YanGu,LiZhao,Xiao-TangWang,Qing-LongGuo.Differentialapoptoticinductionofgambogicacid,anovelanticancernaturalproduct,onhepatomacellsandnormalhepatocytes.CancerLetters.2007,256:259-26.
10.YongYang,YangHu,Hong-YanGu,NaLu,etal.OroxylinAinducesG2/Mphasecell-cyclearrestviainhibitingCdk7-mediatedexpressionofCdc2/p34inhumangastriccarcinomaBGC-823cells.JournalofPharmacyandPharmacology.2008,60(11):1459-63.
11.NaLu,YongYang,Qi-DongYou,YunLing,YingGao,Hong-YanGu,LiZhao,Xiao-TangWang,Qing-LongGuo.GambogicAcidInhibitsangiogenesisthroughsuppressingvascularendothelialgrowthfactor-inducedtyrosinephosphorylationofKDR/Flk-1.CancerLetters.2007.258(1):80-9.（Co-firstauthor）
12.QingZhao,YongYang,JunYu,Qi-DongYou,ShiZeng,Hong-YanGu,NaLu,QiQi,WeiLiu,Xiao-TangWang,Qing-LongGuo.PosttranscriptionalRegulationoftheTelomerasehTERTbyGambogicAcidinHumanGastricCarcinoma823Cells.Cancerletters.2008,262(2):223-31.（Co-firstauthor）
13.YunLing,YongYang,NaLu,Qi-dongYou,SenWang,YingGao,YanChen,Qing-LongGuo.Endostar,anovelrecombinanthumanendostatin,exertsantiangiogeniceffectviablockingVEGF-inducedtyrosinephosphorylationofKDR/Flk-1ofendothelialcells.BiochemicalandBiophysicalResearchCommunications.2007.361:79-84.(Correspondingauthor）
14.LuN,LingY,GaoY,ChenY,MuR,QiQ,LiuW,ZhangH,GuH,WangS,YangY,GuoQ..Endostarsuppressesinvasionthroughdown-regulatingtheexpressionofmatrixmetalloproteinase-2/9inMDA-MB-435humanbreastcancercellsExperimentalBiologyandMedicine.2008,233(8):1013-20..（Correspondingauthor）
15.Hai-WeiZhang,YongYang,KunZhang,LeiQiang,LiYang,LanYang,YangHu,Xiao-TangWang,Qi-DongYou,Qing-LongGuo.WogoninInducedDifferentiationandG1PhaseArrestofHumanU-937LeukemiaCellsviaPKCδPhosphorylation.EuropeanJournalofPharmacology.2008,591(1-3):7-12.（Co-firstauthor）
16.GuH,WangX,RaoS,WangJ,ZhaoJ,RenFL,MuR,YangY,QiQ,LiuW,LuN,LingH,YouQ,GuoQ.Gambogicacidmediatesapoptosisasap53inducerthroughdown-regulationofmdm2inwild-typep53-expressingcancercells.MolCancerTher.2008,7(10):3298-305.
17.HaoLi,Qiu-JuanWang,Dan-NiZhuandYongYang.ReiniosideC,aTriterpeneSaponinofPolygalaaureocaudaDunn,exertsHypolipidemicEffectonHyperlipidemicMice.PhytotherRes.2008;22(2):159-64.（Correspondingauthor）
18.Zhang,Kun;You,Qidong;Yang,Yong;Zhang,Haiwei;Yang,Li;Gu,Hongyan;Qi,Qi;Tan,Zi;Wang,Xiaotang;Guo,Qinglong.WogonininducesthegranulocyticdifferentiationofhumanNB4promyelocyticleukemiacellsandup-regulatesphospholipidscramblase1geneexpression.CancerScience.2008,99(4):689-95.
19.Qi,Qi;Gu,Hongyan;You,Qidong;Yang,Yong;etal.Involvementofmatrixmetalloproteinase2and9ingambogicacidinducedsuppressionofMDA-MB-435humanbreastcarcinomacelllungmetastasis.JournalofMolecularandMedicine.2008,86(12):1367-77.
20.QiQ,LuN,WangXT,GuHY,YangY,LiuW,LiC,YouQD,GuoQL.Anti-invasiveeffectofgambogicacidinMDA-MB-231humanbreastcarcinomacells.BiochemCellBiol.2008,86(5):386-95.
21.LuN,GaoY,LingY,ChenY,YangY,GuHY,QiQ,LiuW,WangXT,YouQD,GuoQL.WogoninsuppressestumorgrowthinvivoandVEGF-inducedangiogenesisthroughinhibitingtyrosinephosphorylationofVEGFR2.LifeSciences.200823;82(17-18):956-63.
22.ChenJ,GuHY,LuN,YangY,LiuW,QiQ,RongJJ,WangXT,YouQD,GuoQL.Microtubuledepolymerizationandphosphorylationofc-JunN-terminalkinase-1andp38wereinvolvedingambogicacidinducedcellcyclearrestandapoptosisinhumanbreastcarcinomaMCF-7cells.LifeSciences.2008;83(3-4):103-9.
23.GuH,YouQ,LiuW,YangY,ZhaoL,QiQ,ZhaoJ,WangJ,LuN,LingH,GuoQ,WangX.GambogicacidinducedtumorcellapoptosisbyTlymphocyteactivationinH(22)transplantedmice.IntImmunopharmacol.2008,8(11):1493-502.
24.ZhaoJ,QiQ,YangY,GuHY,LuN,LiuW,WangW,QiangL,ZhangLB,YouQD,GuoQL.Inhibitionofalpha(4)integrinmediatedadhesionwasinvolvedinthereductionofB16-F10melanomacellslungcolonizationinC57BL/6micetreatedwithGambogicacid.EurJPharmacol.2008,589(1-3):127-31.
25.LuN,LingY,GaoY,ChenY,MuR,QiQ,LiuW,ZhangH,GuH,WangS,YangY,GuoQ..Endostarsuppressesinvasionthroughdown-regulatingtheexpressionofmatrixmetalloproteinase-2/9inMDA-MB-435humanbreastcancercellsExperimentalBiologyandMedicine.2008,233(8):1013-20（Correspondingauthor）
26.JunY,GuoQL,YouQD,ZhaoL,GuHY,YangY,ZhangHW,TanZ,WangX.GambogicacidinducedG2/MphasecellcyclearrestviadisturbingCDK7mediatedphosphorylationofCDC2/P34inhumangastriccarcinomaBGC-823cells.Carcinogenesis.2007,28(3)632-8.
27.QinglongGuo,LiZhao,YongYang，HongyanGu,GuoliangSong,NaLu,JianXin,QidongYou.Anti-hepatitisBvirusactivityofwogonininvitroandinvivo.AntiviralResearch.2007,74(1)16-24.
28.YangHu,YongYang,Qi-DongYou,WeiLiu,Hong-YanGu,LiZhao,KunZhang,WeiWang,Xiao-TangWang,Qing-LongGuo.OroxylinAinducedapoptosisofhumanhepatocellularcarcinomacelllineHepG2wasinvolvedinitsantitumoractivity.BiochemicalandBiophysicalResearchCommunications351(2006)521–527.（Co-firstauthor）
29.WangW,GuoQL,YouQD,ZhangK,YangY,YuJ,LiuW,ZhaoL,GuHY,HuY,TanZ,WangXT.TheAnticancerActivitiesofWogonininMurineSarcomaS180bothinVitroandinVivo.BiolPharmBull.2006;29(6):1132-7.
30.WangW,GuoQ,YouQ,ZhangK,YangY,YuJ,LiuW,ZhaoL,GuH,HuY,TanZ,WangX.Involvementofbax/bcl-2inwogonin-inducedapoptosisofhumanhepatomacelllineSMMC-7721.AnticancerDrugs.200617(7):797-805.
31.YongYang,XingLiu,YanLong,FangWang,Jian-HuaDing,Su-YiLiu,Ye-HongSun,Hong-HongYao,HaiWang,JieWu,GangHu.ActivationofmitochondrialATP-sensitivepotassiumchannelsimprovesrotenone-relatedmotorandneurochemicalalterationsinrats.TheInternationalJournalofNeuropsycopharmacology,2006;9(1):51-61.
32.HuaCHEN,YongYANG,Hong-hongYAO,Xing-chunTANG,Jian-huaDING,HaiWANG,GangHU.Protectiveeffectsofiptakalim,anovelATP-sensitivepotassiumchannelopener,onglobalcerebralischemia-evokedinsultingerbil.ActaPharmacolSin2006,27(6):665-72.（Co-firstauthor）
33.LiuX,WuJY,ZhouF,SunXL,YaoHH,YangY,DingJH,HuG.Theregulationofrotenone-inducedinflammatoryfactorproductionbyATP-sensitivepotassiumchannelexpressedinBV-2cells.NeuroscienceLetters,2006;394(2):131-5.
34.YongYang,XingLiu,YanLong,FangWang,Jian-HuaDing,Su-YiLiu,Ye-HongSun,Hong-HongYao,HaiWang,JieWu,GangHu.Systemicadministrationofiptakalim,anovelATP-sensitivepotassiumchannelopener,preventsrotenone-inducedmotorandneurochemicalalterationsinrats.JournalofNeuroscienceResearch,2005;80(3):442-449.
35.YangY,LiuX,DingJH,LongY,WangF,YaoHH,HuG.Effectsofiptakalimonrotenone-inducedcytotoxicityanddopaminereleasefromPC12cells.NeuroscienceLetters,2004;366(1),53-57.
36.SenWang,Li-fangHu,YongYang,Jian-huaDing,GangHu.StudiesofATP-sensitivepotassiumchannelson6-hydroxydopamineandhaloperidolratmodelsofParkinson’sdisease:ImplicationsfortreatingParkinson’sdisease?Neuropharmacology,2005;48(7):984-992.