王小兵个人简介

王小兵，男，1978年5月出生，副教授，硕士生导师，研究领域为天然活性成分的研究与开发。
2001年毕业于汉中师范学院，获化学教育专业学士学位；2005年毕业于陕西师范大学，获有机化学专业硕士学位；2008年毕业于中国药科大学，获药物化学专业博士学位。2008年7月留校天然药物化学教研室工作，2011年6月晋升副教授。主持江苏省自然科学基金青年项目一项，参与多项国家和省部级基金项目。
研究方向：
1）天然产物结构修饰与全合成；
2）基于天然产物的合理药物设计与研究；
3）天然产物生物转化研究。
主要论文：
1)S.S.Xie,X.B.Wang*,J.Y.Li,L.Yang,L.Y.Kong*,Design,synthesisandevaluationofnoveltacrine-coumarinhybridsasmultifunctionalcholinesteraseinhibitorsagainstAlzheimer'sdisease,EuropeanJournalofMedicinalChemistry,2013,64,540-553.
2)S.S.Xie,X.B.Wang*,J.Y.Li,L.Y.Kong*,Design,SynthesisandBiologicalEvaluationofNovel7-MercaptocoumarinDerivativesasα₁-AdrenoceptorAntagonists,Chemical&PharmaceuticalBulletin,2013,61,16-24.
3)X.J.Hu,X.B.Wang,L.Y.Kong*,α-GlucosidaseInhibitorsviaGreenPathway:BiotransformationforBicoumarinsCatalyzedbyMomordicacharantiaPeroxidase,JournalofAgriculturalandFoodChemistry,2013,61,1501-1508.
4)R.S.Li,X.B.Wang,X.J.Hu,L.Y.Kong*,Design,synthesisandbiologicalevaluationofflavonoidderivativesaspotentialmulti-functionalacetylcholinesteraseinhibitor,Bioorganic&MedicinalChemistryLetters,2013,23,2636-2641.
5)F.Z.Bao,X.B.Wang,L.Y.Kong*,Pyrrolidinecatalyzednoveldominoreactionforthesynthesisofpolysubstituted4-oxocyclohexanecarbaldehydederivatives,TetrahedronLetters,2013,54,1405-1408.
6)X.B.Wang,W.Liu,L.Yang,Q.L.Guo,L.Y.Kong*,Investigationonthesubstitutioneffectsoftheflavonoidsaspotentanticanceragents:astructure-activityrelationshipsstudy,MedicinalChemistryResearch,2012,21,1833-1849.
7)L.B.Wang,X.B.Wang,L.Y.Kong*,AutomaticauthenticationanddistinctionofEpimediumkoreanumandEpimediumwushanensewithHPLCfingerprintanalysisassistedbypatternrecognitiontechniques,BiochemicalSystematicsandEcology,2012,40,138-145.
8)X.B.Wang,Y.Zhang,J.S.Wang,H.Q.Yao,H.B.Sun,L.Y.Kong*,Spectroscopiccharacterizations,X-raystudies,andelectroniccirculardichroismcalculationsoftwoalkaloidtriterpenoids,StructuralChemistry,2011,22,1241-1248.
9)C.S.Yang,X.B.Wang,J.S.Wang,J.G.Luo,J.Luo,L.Y.Kong*,A2+2CycloadditionDimerandaDiels-AlderAdductfromAlpiniakatsumadai,OrganicLetters,2011,13,3380-3383.
10)X.Wan,X.B.Wang,M.H.Yang,J.S.Wang,L.Y.Kong*,DimerizationofpiceatannolbyMomordicacharantiaperoxidaseandα-glucosidaseinhibitoryactivityofthebiotransformationproducts,Bioorganic&MedicinalChemistry,2011,19,5085-5092.
11)J.Jin,X.B.Wang,L.Y.Kong*,Design,synthesisandbiologicalevaluationofnewarylpiperazinederivativesbearingaflavonemoietyasα₁-adrenoceptorantagonists,Bioorganic&MedicinalChemistryLetters,2011,21,909-911.
12)Z.F.Guo,X.B.Wang,J.G.Luo,J.Luo,J.S.Wang,L.Y.Kong*,AnovelaporphinealkaloidfromMagnoliaofficinalis,Fitoterapia,2011,82,637-641.
13)Z.Xu^#,X.B.Wang^#,Y.Dai*,L.Y.Kong*,F.Y.Wang,H.A.Xu,D.Lu,J.Song,Z.G.Hou,(+/-)-PraeruptorinAenantiomersexertdistinctrelaxanteffectsonisolatedrataortaringsdependentonendotheliumandnitricoxidesynthesis,Chemico-BiologicalInteractions,2010,186,239-246.
14)X.B.Wang,S.Z.Hua,L.Y.Kong*,CrystalstructureofsumadainA4-bromobenzoate,C₃₇H₃₇BrO₅,ZeitschriftFurKristallographie-NewCrystalStructures,2010,225,713-714.
*Correspodingauthor

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